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Does flexible small-diameter colonoscope reduce insertion pain during colonoscopy?

World Journal of Gastroenterology 2000年第5期6卷 659-663页

作者： Yoshiharu Uno akihiro munakata First Department of Medicine School of MedicineHirosaki University036- 8216Japan

AIM It is well known that colonoscopy can bedifficult due to abdominal pain induced duringcolonoscope insertion,if sedative agents are ***,an extra-flexible,small-diameter colonoscope(CF-SV,Olympus Inc.,Japan)was developed in order to improve safetyand *** aim of this study was toaccess the usefulness of the *** One hundred patients undergoingsigmoidoscopy were recruited and colonoscopywas performed by one ***,a routine-type colonoscope(CF-2301)was inserted into the colon *** the patient complained ofabdominal pain(even if mild),the scope wasnot advanced further and was withdrawn afterthe anatomic location of its tip was ***,the CF-SV was inserteduntil it reached the cecun or the site whereabdominal pain *** abdominalsurgery and abdominal disease were consideredas unfavorable factors(UF)and the relationshipbetween abdominal pain and UF,age and genderwere ***,the colonicinsertion pressures in 36 patients with abdominalpain were measured with a force *** Thirty-four cases(34%)felt no painwith the CF-2301 and successful pancolon-0scopies to the cecum were ***-six cases(66%)complained of abdominal *** procedure was painless for 47% of men and24% of women,*** CF-2301 scopefailed to reach the sigmoid-descending colon junctions in 59(89.4%)of the 66 patientscomplaining of abdominal ***,CF-SVreached proximal area in 94.9% of those whofailed with *** median pressure forpain-inducing was 700 g/cm^*** Unsedated patients with UFwere prone to complain of pain when thestandard-type CF-2301 scope was *** developed extra-flexible CF-SV is usefulfor the aged and for those with UF or being proneto suffer from abdominal *** agentsmay be unnecessary if this new type ofcolonoscope is used.

关键词： colonoscopy abdominal pain flexible colonoscope insertion pressure unfavorable factors sigmoidoscopy

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Relation of CagA seropositivity to cagPAI phenotype and histological grade of gastritis in patients with Helicobacter pylori infection

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World Journal of Gastroenterology 2005年第24期11卷 3751-3755页

作者： Tadashi Shimoyama Shinsaku Fukuda Fumika Nakasato Tetsuro Yoshimura Tatsuya Mikami akihiro munakata First Department of Internal Medicine

AIM: Infection with Helicobacter pylori(H pylori) possessing the cag pathogenicity island (PAI) has been associated with severe clinical outcome and CagA-antibody has been used to indicate cagPAI-positive infection. The aim of this study was to examine the accuracy of CagA seropositivity to indicate the virulence of the cagPAI in Japan. METHODS: Sixty isolates of H pylori cultured from gastric biopsies were examined by polymerase chain reaction assays for the presence of cagA, cagE and VirD4. Anti CagA IgG antibody in matching sera was tested by both ELISA and immunoblot assay. Histological grade of gastritis was graded according to the updated Sydney System. RESULTS: Amongst 53 patients infected with cagA+/cagE+/ VirD4+ strain, 38 were CagA seropositive. There were four patients infected with strains possessing incomplete cagPAI. Two out of three patients with cagA+/cagE-/VirD4- infection were CagA seropositive, while a patient with cagA-/cagE+/ VirD4+ infection was CagA seronegative. Accuracy of ELJSA to predict bacterial possession of cagA was 61.7% whereas 58.3% for cagE and VirD4. The immunoblot assay showed relatively higher sensitivity and showed better accuracy. The lower grade of gastric mucosal inflammatory infiltration was seen in false CagA-seronegative patients. CONCLUSION: Some serodiagnosis does not seem to have enough accuracy to indicate virulence of cagPAI, particularly in infection of strains with incomplete cagPAI. The degree of gastric mucosal inflammation may affect the results of CagA serodiagnosis.

关键词： CagA seropositivity cagPAI Gastric inflammation

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Withdrawing method of the stiffening tube incidentally inserted into the descending colon

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World Journal of Gastroenterology 2005年第34期11卷 5390-5391页

作者： Shinsaku Fukuda Tatsuya Mikami Tadashi Shimoyama Norihiro Hanabata Hideki Iwamura akihiro munakata First Department of Internal Medicine Hirosaki University School of Medicine Hirosaki Japan Tsugaru Center Hospital for Adult Tsugaru Japan

We experienced a very rare complication of colonoscopy,a migration of stiffening tube into the colorectum. We herein introduce a withdrawing method of migrating stiffening tube incidentally inserted into the colorectum.A 65-year-old Japanese woman underwent colonoscopy because of abdominal discomfort. We used stiffening tube to insert the scope to the proximal colon because of her redundant sigmoid colon. When withdrawing the scope,we realized that the tube was fully inside the *** could not remove the tube instantly, and it reached the splenic flexure, finally. We reinserted the scope through the migrating tube, straightened the scope, and withdrew it holding a slight angle of the scope over the proximal end of the tube. Then, we could safely remove the tube along with the scope through the anus.

关键词： Colonoscopy Complication Migration Stiffening tube

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Acute esophageal necrosis caused by alcohol abuse

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World Journal of Gastroenterology 2005年第35期11卷 5568-5570页

作者： Tetsu Endo Juichi Sakamoto Ken Sato Miyako Takimoto Koji Shimaya Tatsuya Mikami akihiro munakata Tadashi Shimoyama Shinsaku Fukuda First Department of Internal Medicine Hirosaki University School of Medicine 5 Zaifucho Hirosaki Aomori 036-8562 Japan

Acute esophageal necrosis (AEN) is extremely rare and the pathogenesis of this is still unknown. We report a case of AEN caused by alcohol abuse. In our case, the main pathogenesis could be accounted for low systemic perfusion caused by severe alcoholic lactic acidosis. After the healing of AEN, balloon dilatation was effective to manage the stricture.

关键词： Esophagus Lactic acidosis Alcohol drinking Balloon dilatation

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In-Tube Rocket Propulsion Using Repetitive Laser Pulses

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Journal of Thermal Science 2011年第3期20卷 201-204页

作者： akihiro Sasoh Department of Aerospace Engineering Nagoya UniversityFuro-choChikusa-kuNagoya 464-8603Japan

In 'in-tube propulsion,' that is the combination of conventional rocket propulsion and ballistic range operation,propulsion performance can be enhanced with increases in thrust due to spatial confinement and in payload capa-bility because propellant can be placed off board a *** paper describes proofed concepts of in-tube propulsion by using repetitive laser pulses.

关键词： Propulsion Laser Thrust Blast wave Ablation

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Flow Structure Around the Intake of a Vertical Pump

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Journal of Thermal Science 2006年第2期15卷 121-125页

作者： akihiro WADA Research and Development Dept. Torishima Pump MFG. Co. Ltd. 1-1-8 Miyata-cho Takatsuki Osaka 569-8660 Japan

The flow structure around the intake of a vertical pump is investigated experimentally and numerically in order to obtain a guideline in designing the optimum shape of the intake of vertical pumps, in which their installation area is demanded to be minimum without losing the high performance. We concentrate our attention on the expansion ratio of the intake as a representative characteristic of the shape of the pumps and investigate the effect of the expansion ratio on pump performance. It is concluded that the optimum expansion ratio ranges in 1.1-1.2 if we take into consideration that the area needed for the installation of the pump should be minimum.

关键词： vertical pump shape of intake flow structure around the intake

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Screening of functionalized self-assembling peptide nanofiber scaffolds with angiogenic activity for endothelial cell growth

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Progress in Natural Science:Materials International 2011年第2期21卷 111-116页

作者： akihiro HORII Olympus America Inc. 3500 Corporate ParkwayCenter ValleyPA 18034USA

Promotion of angiogenesis in tissue engineering is of vital significance to the survival of transplants,which leads the way of tissue *** this study,we screened six short peptides with potentially angiogenic activities to functionalize self-assembling peptide nanofiber scaffolds RADA16-I(Ac-(RADA)4-CONH2).Fluorescence microscopy images of endothelial cells morphology on peptide scaffolds exhibited good cell attachments and Survivals on these six functionalized peptide scaffolds, especially on peptide scaffolds RAD/KLT and RAD/*** proliferation examination also confirmed the excellent cell growth on these two functionalized peptide *** peptide motifs KLT(KLTWQELYQLKYKGI) and PRG(PRGDSGYRGDS) had positive effects on endothelial cell survival and growth,which implied that these two peptides might have great promise for promoting angiogenesis in vitro and in vivo.

关键词： self-assembling peptide angiogenesis tissue engineering endothelial cell

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New microscopic wave function of α-condensation

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Frontiers of physics 2011年第3期6卷 320-336页

作者： akihiro TOHSAKI Research Center for Nuclear Physics Osaka University Ibaraki-shi Osaka 567-0047 Japan

We explain how to treat a microscopic wave function of α-condensation taking a 3α-nucleus as a typical example. The wave function has been originally proposed ten years before by Horiuehi, Ropke, Schuck and the present author （Phys. Rev. Lett., 2001, 87： 192501）. The microscopic model, which fully takes into account the Pauli principle between all the constituent nucleons, effective inter- nucleon forces and the Coulomb force, can play an important role in reproducing an α-gas nature thanks to α-condensation as an excited state of α-like nuclei. An essential point of the wave function is to describe their ground state simultaneously. We study its typical features by giving an analytical formula of the norm kernel and the kernel concerning the one-body operator for 3α-condensation.

关键词： α-cluster model analytical formula α-condensation

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Krein Parameters of Fiber-Commutative Coherent Configurations

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Algebra Colloquium 2020年第1期27卷 1-10页

作者： Keiji Ito akihiro Munemasa Research Center for Pure and Applied Mathematics Graduate School of Information SciencesTohoku UniversitySendaiJapan

For fiber-commutative coherent configurations,we show that Krein parameters can be defined essentially *** a consequence,the general Krein condition reduces to positive semidefiniteness of finitely many matrices determined by the parameters of a coherent *** mention its implications in the coherent configuration defined by a generalized *** also simplify the absolute bound using the matrices of Krein parameters.

关键词： coherent configuration association scheme Krein parameter Krein condition generalized quadrangle absolute bound

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Effect of a Curved Duct Upstream on Performance of Small Centrifugal Compressors for Automobile Turbochargers

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Journal of Thermal Science 2013年第1期22卷 92-96页

作者： Shigeta Kikuchi Nobuhiko Yamasaki akihiro Yamagata Department of Aeronautics and Astronautics Kyushu University Products Development Center IHI Corporation

Since the automobile turbochargers are installed in an engine compartment with limited space, the ducts upstream of the turbocharger compressor may be curved in a complex manner. In the present paper, the effect of a curved duct upstream on performance of small centrifugal compressors for automobile turbochargers is discussed. The computational fluid dynamics (CFD) analysis of a turbocharger compressor validated for the compressor model with the straight pipe applied to the compressor with the curved pipe are executed, and the deterioration of the performance for the curved pipe is confirmed. It is also found that the deterioration of compressor performance is caused by the interaction of the secondary flow and the impeller.

关键词： Cartesian grid cylindrical grid validation calculation

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