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中国神经科学学会第十二届全国学术会议

作者： ak guo Ke Zhang Haifeng SU Institute of Neuroscience State Key Laboratory of Neuroscience CAS Center for Excellence in Brain Science and Intelligence TechnologyShanghai Institutes for Biological Sciences Chinese Academy of Sciences Institute of Biophysics State Key Laboratory of Brain and Cognitive Science Chinese Academy of Sciences

"Nothing in neurobiology makes sense except in the light of behaviour"（***, 1994）. "Action selection is the main task of the brain"（***,2013）. How can we generate the right behavior at the right moment and the right place? Decision making is essential for the behaviorselection. We have designeda ‘color/position’ dilemma in the visual flight simulator to study the value–based decision-makingin Drosophila. Individual flies were conditioned to choose a flight path in accordance with the color（green and blue） and position（upper and lower） cues and then confronted with choice test with color and position cues reversed after *** results revealed that wild-type flies are able to resolve this paradoxical situation by evaluating the ‘relative value’ of the current information and making a nonlinear ‘winner-takes-all’ *** decision curve exhibited a clear-cut and sigmoid-like function（Tang and guo, 2001）. We found that flies with defective dopamine system or MBs（mushroom bodies, a part of fly’s central brain, as a centerof free will or intelligent control） functionhave trouble in deciding between the two conflicting visual features（Zhang et al,2007）.Lastly we have found thata pair of APLneuron（the anterior paired lateral GABAergic inhibitory neuron）（Liu and Davis,2009）, which densely innervate the MB, is also involved in the salience-based decision-making that genetic silencing of APL neurons turns the nonlinear choice behavior into linear one（Su et al., in preparation）. This effect was mediated by ionotropic GABAA receptors, RDL, which is highly expressed in all lobes of the MB（Liu et al., 2009）.Together, we suggest a Gain-Gating Mechanism of decision making that during decision making process the one option（"winner"）will be inflated by the Dopamine Gain Mechanism, while the alternative one（"loser"） will be rejected by GABA Inhibition Gating resulting in "Winner takes all".We believe that our Gain-Gating framework may provide a template for

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Reducing subspaces of tensor products of weighted shifts

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Science China Mathematics 2016年第4期59卷 715-730页

作者： guo KunYu WANG XuDi School of Mathematical Sciences Fudan University School of Sciences Xi'an University of Technology

A unilateral weighted shift A is said to be simple if its weight sequence {α_n} satisfies ▽~3(α_n^2)≠0for all n≥*** prove that if A and B are two simple unilateral weighted shifts,then AI+IB is reducible if and only if A and B are unitarily *** also study the reducing subspaces of A^kI+IB^l and give some *** an application,we study the reducing subspaces of multiplication operators Mzk+αωl on function spaces.

关键词： unilateral weighted shifts reducing subspaces multiplication operators von Neumann algebra

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Vacancy defect MoSeTe embedded in N and F co-doped carbon skeleton for high performance sodium ion batteries and hybrid capacitors

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Journal of Energy Chemistry 2024年第3期90卷 652-664,I0014页

作者： Dehui Yang Wentao guo Fei guo Jiaming Zhu Gang Wang Hui Wang Guanghui Yuan Shenghua Ma Beibei Wang State Key Laboratory of Photon-Technology in Western China Energy International Collaborative Center on Photoelectric Technology and Nano Functional MaterialsInstitute of Photonics&Photon-TechnologyNorthwest UniversityXi’an 710127ShannxiChina Key Laboratory of Synthetic and Natural Functional Molecule Chemistry(Ministry of Education) College of Chemistry&Materials ScienceNorthwest UniversityXi’an 710127ShannxiChina School of Chemistry and Chemical Engineering Ankang Research Centre of New Nano-materials Science and TechnologyShaanxi University Innovation Research Institute of Advanced Energy Storage Materials and Battery Technology for Future IndustrializationAnkang UniversityAnkang 725000ShannxiChina

Sodium-ion batteries(SIBs) and hybrid capacitors(SIHCs) have garnered significant attention in energy storage due to their inherent advantages,including high energy density,cost-effectiveness,and enhanced ***,developing high-performance anode materials to improve sodium storage performa nce still remains a major ***,a facile one-pot method has been developed to fabricate a hybrid of MoSeTe nanosheets implanted within the N,F co-doped honeycomb carbon skeleton(MoSeTe/N,F@C).Experimental results demonstrate that the incorporation of large-sized Te atoms into MoSeTe nanosheets enlarges the layer spacing and creates abundant anion vacancies,which effectively facilitate the insertion/extraction of Na^(+) and provide numerous ion adsorption sites for rapid surface capacitive ***,the heteroatoms N,F co-doped honeycomb carbon skeleton with a highly conductive network can restrain the volume expansion and boost reaction kinetics within the *** anticipated,the MoSeTe/N,F@C anode exhibits high reversible capacities along with exceptional cycle *** coupled with Na_(3)V_(2)(PO_(4))_(3)@C(NVPF@C) to form SIB full cells,the anode delivers a reversible specific capacity of 126 mA h g^(-1) after 100 cycles at 0.1 A g^(-1).Furthermore,when combined with AC to form SIHC full cells,the anode demonstrates excellent cycling stability with a reversible specific capacity of50 mA h g^(-1) keeping over 3700 cycles at 1.0 A g^(-1).In situ XRD,ex situ TEM characterization,and theoretical calculations(DFT) further confirm the reversibility of sodium storage in MoSeTe/N,F@C anode materials during electrochemical reactions,highlighting their potential for widespread practical *** work provides new insights into the promising utilization of advanced transition metal dichalcogenides as anode materials for Na^(+)-based energy storage devices.

关键词： MoSeTe N F co-doped honeycomb carbon skeleton Sodium-ion batteries Sodium-ion hybrid capacitor

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Finite groups with systems of Σ-embedded subgroups

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Science China Mathematics 2011年第9期54卷 1909-1926页

作者： guo WenBin SKIBA Alexander N Department of Mathematics University of Science and Technology of China Hefei 230026 China Department of Mathematics Francisk Skorina Gomel State University Gomel 246019 Belarus

In recent years,a series of papers about cover-avoiding property of subgroups appeared and all the studies were connected with chief factors of a finite ***,about the cover-avoiding property of subgroups for non-chief factor,there is no study up to *** purpose of this paper is to build the *** A be a subgroup of a finite group G and Σ:G0≤G1≤…≤Gn some subgroup series of *** that for each pair(K,H) such that K is a maximal subgroup of H and G i 1 K < H G i for some i,either A ∩ H = A ∩ K or AH = *** we say that A is Σ-embedded in *** this paper,we study the finite groups with given systems of Σ-embedded *** basic properties of Σ-embedded subgroups are established and some new characterizations of some classes of finite groups are given and some known results are generalized.

关键词： finite group ∑-embedded subgroups ∑p-embedded subgroup soluble group supersoluble group p-nilpotent group saturated formation

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Tsai Chiao:The founder of physiology and aviation,aerospace and navigation medicine in China

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Protein & Cell 2022年第11期13卷 779-784页

作者： Yalan Wang Zijian Li Yanyan Qian Benyu guo Psychology College Nanjing Normal UniversityNanjing 210097China Social and Behavioural Sciences Faculty Leiden University2333 AK LeidenNetherlands

On February 16th,2019,Tsai Academician Museum held a launch ceremony of a minor planet(207681)'s settling in Jieyang County,Guangdong *** minor planet was given a new name Cai Qiao(Fig.1)on October 14th,*** Qiao was discovered at Xu Yi Station in the Purple Hills Observatory of the Chinese Academy of Sciences on August 16th,*** who is the planet named after?

关键词： Academician planet aviation

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Obtaining the best possible predictions of habitat selection for wintering Great Bustards in Cangzhou, Hebei Province with rapid machine learning analysis

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Chinese Science Bulletin 2014年第32期59卷 4323-4331页

作者： Chunrong Mi Falk Huettmann Yumin guo College of Nature Conservation Beijing Forestry University EWHALE Laboratory Department of Biology and WildlifeInstitute of Arctic Biology University of Alaska Fairbanks Biology Fairbanks AK 99775 USA

Great Bustards(Otis tarda dybowskii)are one of the world’s heaviest flying birds,occupying grassland habitats in Eastern *** study is located at the most eastern Chinese wintering site in Cangzhou,Hebei Province,where approximately 100 individuals are concentrated in a small area(17.53 km2).Solid information is still lacking about the wintering areas for this subspecies in its eastern range and specifically for *** study area consists of intensely used farmland in proximity to humans and is lacking conservation areas and wild,open ***,we present our results from two years of field data collection on habitat *** choose a machine learning model approach based on a rapid assessment methodology for the winter habitat of the Great *** is based on a spatial analysis of the best available environmental data,which were collected relatively *** relatively new methods in ecology are based on an ensemble of decision trees and include algorithms such as TreeNet,Random Forest and CART used in *** this study,we collected bustard droppings(presence only)from 48 locations between December 2011 and January 2012 and used the sites as training *** from 23 locations were collected in November 2012,and those sites were used as test *** used eight environmental variables as predictor layers for the response variable of bustard presence/*** employed a Geographic Information System(ArcGIS 10.1and Geospatial Modelling Environment)and Google *** with the other three models,we found that predictions from Random Forest obtained a significant difference between presence and *** to this model,the three most important factors for wintering Great Bustards are distance to residential area,distance to water pools,and farmland *** model shows that wintering Great Bustards prefer locations that are over 400 m away from residential areas,within 900 m of water pools and on areas of farmland smal

关键词：河北省沧州市栖息地选择机器学习越冬地大鸨预测地理信息系统野外数据采集

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Maize orthologs of rice GS5 and their transregulator are associated with kernel development

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Journal of Integrative Plant Biology 2015年第11期57卷 943-953页

作者： Jie Liu Min Deng Huan guo Sharif Raihan Jingyun Luo Yuancheng Xu Xiaofei Dong Jianbing Yan National Key Laboratory of Crop Genetic Improvement Huazhong Agricultural University

Genome information from model species such as rice can assist in the cloning of genes in a complex genome, such as maize. Here, we identified a maize ortholog of rice GS5 that contributes to kernel development in maize. The genome- wide association analysis of the expression levels of ZmGSs, and 15 of its 26 paralogs, identified a trans-regulator on chromosome 7, which was a Bak1-1ike gene. This gene that we named as ZmBak1-7 could regulate the expression of ZmGS5 and three of the paralogs. Candidate-gene association analyses revealed that these five genes were associated with maize kernel development-related traits. Linkage analyses also detected that ZINGS5 and ZmI3ak1-7 co-localized with mapped QTLs. A transgenic analysis of ZINGS5 in Arabidopsis thaliana L. showed a significant increase in seed weight and cell number, suggesting that 2mG55 may have a conserved function among different plant species that affects seed development.

关键词： Association analysis kernel development maize ZmBak1-7 ZmGS5

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Sinucrassins A-K, Casbane-type Diterpenoids from the South China Sea Soft Coral Sinularia crassa

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Chinese Journal of Chemistry 2021年第9期39卷 2367-2376页

作者： Meng-Jun Wu Jiao Liu Jian-Rong Wang Juan Zhang Hong Wang Cheng-Shi Jiang Yue-Wei guo Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals and College of Pharmaceutical Science Zhejiang University of TechnologyHangzhouZhejiang 310014China State Key Laboratory of Drug Research Shanghai Institute of Materia MedicaChinese Academy of Sciences555 Zu Chong Zhi RoadZhangjiang Hi-Tech ParkShanghai 201203China School of Biological Science and Technology University of JinanJinanShandong 250022China

A detailed chemical study on the Hainan soft coral Sinularia crass has resulted in the isolation and characterization of eleven cas-bane-type diterpenoids,named sinucrassins A-K(1-11),along with six known related ones(12-17).Their structures were elucidated by extensive spectroscopic analyses and comparison with the reported *** absolute configurations of new compounds were determi ned by the X-ray diffracti on analysis and computer-assisted structural elucidati on in eluding 13C NMR data calculati on and time-dependent density functional theory/electronic circular dichroism calculation.

关键词： Sinularia crassa Casbane-type diterpenoid Configuration determination X-ray diffraction NMR spectroscopy

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Biological productivity and carbon cycling in the Arctic Ocean

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Chinese Science Bulletin 2002年第12期47卷 1037-1040页

作者： CHEN Min HUANG Yipu guo Laodong CAI Pinghe YANG Weifeng LIU Guangshan QIU Yusheng Department of Oceanography Xiamen UniversityXiamen 361005China International Arctic Research Center University of AlaskaFairbanksAK 99775USA

Primary production, bacterial production, par-ticulate organic carbon fluxes and organic carbon burial rates were quantified during the summer period of 1999 in the Arctic Ocean via 14C uptake, 3H uptake, 234Th/238U disequilibrium and 210Pbex dating, respectively. The integrated primary production in the water column was as high as 197 mmolC/(m2·d) in the Chukchi shelf and was 3.8 mmolC/(m2·d) in the Canada Basin. These rates are higher than those reported previously. The ratios of bacterial production to primary production in the study region were higher than 0.5, indicating that microbial activity is not depressed but important in cold Arctic waters. 234Th/238U dis-equilibria were evident at the station in the Canada Basin. The presence of significant 234Th deficiency suggested that scavenging and removal processes are also important to bio-geochemical cycles of trace elements in the Arctic Ocean. Particulate organic carbon export flux was estimated to be 1.0 mmolC/(m2·d). Measurements of sediment

关键词： Arctic Ocean primary production bacterial production POC export flux organic carbon burial rate isotopic tracer.

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温肾通督方促进小鼠脊髓损伤的修复

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中国组织工程研究 2025年第6期29卷 1118-1126页

作者：赵瑞华陈思娴郭杨石磊吴承杰吴毛杨光露张昊恒马勇南京中医药大学中医学院·中西医结合学院江苏省南京市210023 南京中医药大学骨伤修复与重建新技术实验室江苏省南京市210023 南京中医药大学无锡附属医院江苏省中医退行性骨关节病临床医学创新中心江苏省无锡市214071

背景:前期研究证实,温肾通督方可通过抑制脾脏B细胞焦亡、促进微血管内皮细胞吞噬髓鞘碎片、影响小胶质细胞迁移和浸润、促进受损神经元恢复、降低脊髓损伤后神经元凋亡等促进脊髓损伤恢复,但其机制尚不明确。目的:探讨温肾通督方对脊... 详细信息

背景:前期研究证实,温肾通督方可通过抑制脾脏B细胞焦亡、促进微血管内皮细胞吞噬髓鞘碎片、影响小胶质细胞迁移和浸润、促进受损神经元恢复、降低脊髓损伤后神经元凋亡等促进脊髓损伤恢复,但其机制尚不明确。目的:探讨温肾通督方对脊髓损伤小鼠髓系细胞触发受体2(triggering receptor expressed on myeloid cells 2,TREM2)及PI3K/akt信号通路的影响。方法:取36只C57BL/6小鼠,采用随机数字表法分为假手术组、模型组、温肾通督方组,每组12只。模型组与温肾通督方组采用改良Allen’s法制备小鼠T10脊髓损伤模型,造模后第1天,温肾通督方组灌胃给予温肾通督方,假手术组、模型组灌胃给予生理盐水,每天1次,连续给药28 d。给药期间,通过BMS评分和斜板实验评价各组小鼠运动功能;造模后第7,28天,采用苏木精-伊红染色观察各组小鼠脊髓组织病理变化,免疫荧光染色双标法检测脊髓组织离子化钙结合适配分子1(ionized calcium binding adaptor molecule 1,IBA1)、TREM2蛋白表达,Western blot检测脊髓组织TREM2、PI3K、p-PI3K、akt、p-akt、Bcl2、Bax、Caspase3蛋白表达。结果与结论:①BMS评分和斜板实验结果表明,脊髓损伤造模后小鼠后肢运动功能下降,而经过温肾通督方治疗后,脊髓损伤小鼠后肢运动功能明显提升。②苏木精-伊红染色结果显示,与模型组比较,温肾通督方小鼠脊髓组织病理结构明显改善,表现为背侧白质和神经元萎缩程度、细胞质空泡化降低及炎性细胞浸润减少等。③免疫荧光染色结果显示,造模后第7天,模型组IBA1、TREM2蛋白表达均低于假手术组(Pakt蛋白表达及Bcl2/Bax比值降低(Pakt、Bax蛋白表达及p-akt/akt比值升高(Pakt、p-akt、Bcl2蛋白表达及p-PI3K/PI3K、p-akt/ak、Bcl2/Bax比值升高(Pakt、p-akt、Bcl2蛋白表达及Bcl2/Bax比值降低(Pakt、p-akt、Bcl2蛋白表达及Bcl2/Bax比值升高(Pakt信号通路,抑制神经元凋亡发挥神经保护作用,进而促进脊髓损伤的修复。

关键词：脊髓损伤温肾通督方小胶质细胞髓系细胞触发受体2 PI3K/akt信号通路

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