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Transcriptome analysis reveals immune-related genes in tissues of Vibrio anguillarum-infected turbot Scophthalmus maximus

第十三届全国植物基因组学大会

作者： aijaz ahmed soomro Institute of Crop Sciences/national Key Facility For Crop Gene Resources & Genetic Improvement Chinese Academy of Agricultural Sciences

Rice grows in acid soils is easily subject to zinc toxicity which harms the growth of rice *** aim of this study was to identify quantitative trait loci(QTL) underlying zinc toxicity tolerance(ZTT) of rice using the 194 advanced backcross introgression lines which were derived from a cross between Lemont(japonica) and Teqing(indica) in Lemont background,and 384 evenly distributed single nucleotide

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Journal of Oceanology and Limnology 2024年第1期42卷 332-344页

作者： Yuting SONG Maqsood ahmed soomro Xianzhi DONG Guobin HU College of Marine Life Sciences Ocean University of ChinaQingdao 266003China Institute of Evolution&Marine Biodiversity Ocean University of ChinaQingdao 266003China Institute of Biophysis Chinese Academy of SciencesBeijing 100101China

Turbot Scophthalmus maximus is an important mariculture fish species with high economic ***,the bacterial diseases caused by Vibrio anguillarum infection bring huge economic losses to the turbot aquaculture *** understand the immune response of the turbot against *** infection and to explore novel immune-related genes,the transcriptome analysis of turbot spleen and gills were conducted after *** *** expressed genes(DEGs)were identified in spleen and gill of the turbot amounted to 17261 and 16436,respectively.A large number of immunerelated DEGs were enriched in cytokine-cytokine receptor interaction signaling pathway,and the others by the kyoto encyclopedia of genes and genomes(KEGG)*** gene ontology(GO)classification analysis revealed that *** infection had the greatest effect on biological processes and cellular *** immune-related DEGs were identified in the spleen(cstl.1,egfl6,lamb21,v2rx4,calcr,and gpr78a)and gills(ghra,sh3gl2a,cst12,inhbaa,cxcl8,and il-1b)by heat *** proteinprotein interaction(PPI)networks were constructed to analyze the immune *** results demonstrate that the maturation and antigen processing of major histocompatibility complex(MHC)class II molecule,and calcitonin-or adrenomedullin-regulated physiological activity were important events in the immunity of turbot against *** *** the gills,the protein interactions in TGF-βsignaling pathway,production of inflammatory factors,and endocytosis regulation were most *** research laid a foundation for discovering novel immune-related genes and enriching the knowledge of immune mechanisms of turbot against *** infection.

关键词： Scophthalmus maximus Vibrio anguillarum transcriptome differentially expressed genes immune mechanism

利用双向回交导入系定位水稻苗期耐亚铁毒和锌毒的QTL

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作物学报 2013年第10期39卷 1754-1765页

作者：张建 aijaz ahmed soomro 柴路崔彦茹王小倩郑天清徐建龙黎志康中国农业科学院作物科学研究所/农作物基因资源与基因改良国家重大科学工程北京100081

铁和锌是水稻生长必需的微量元素,但在低洼或酸性土壤中,过量的二价铁和锌对水稻生长具毒害作用,最终造成生物量和产量下降。为探讨水稻苗期耐亚铁毒、锌毒的遗传机制,利用优质粳稻品种Lemont和高产籼稻品种特青为亲本构建的高代双向回... 详细信息

铁和锌是水稻生长必需的微量元素,但在低洼或酸性土壤中,过量的二价铁和锌对水稻生长具毒害作用,最终造成生物量和产量下降。为探讨水稻苗期耐亚铁毒、锌毒的遗传机制,利用优质粳稻品种Lemont和高产籼稻品种特青为亲本构建的高代双向回交导入系和308个在染色体上均匀分布的SNP标记剖析耐亚铁毒、锌毒相关的QTL。从双向导入系共检测到42个影响耐亚铁毒、锌毒相关性状如苗高、苗干重、根干重以及胁迫与对照相对值的QTL,多数位点增强亚铁毒、锌毒抗性的有利等位基因来自Lemont。其中同时在2个背景下表达的QTL有4个,占定位QTL总数的9.52%,说明大多数QTL的表达具有明显的遗传背景效应。同一遗传背景下同时影响耐亚铁毒和锌毒的QTL有9个,其中QSdw5在2个背景中均被检测到,其效应大小和方向一致,说明水稻苗期耐亚铁毒、锌毒之间存在遗传重叠位点。因此,通过分子标记辅助选择从Lemont中导入或聚合有利的遗传重叠区域,可以提高特青对亚铁毒、锌毒的抗性水平。

关键词：耐亚铁毒害耐锌毒害 QTL SNP 水稻

The surveillance of arsenic levels in the drinking water of primary schools and the assessment of the potential cancer-related health risks of children in Multan, Pakistan

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Emerging Contaminants 2024年第1期10卷 17-23页

作者： Hidayatullah Mahar Abdul Rehman Memon Aqsa Ishfaq Suhail ahmed soomro Mehran University of Engineering&Technology JamshoroPakistan NFC Institute of Engineering&Technology MultanPakistan

To investigate the levels of arsenic(As)in the groundwater and drinking water of primary schools and their potential impact on human health is main objective of this *** assess risk,the following parameters i.e.,carcinogenic indices(CI),hazardous indexes(HI),carcinogenic risk(CR),and hazardous quotient(HQ)have been measured for both dermal and oral arsenic *** study has been focused on primary schools located in four tehsils of Multan,where water samples were *** levels,with concentrations ranging from 3.31 to 191 mg/l,exceeding the safe limit set by the World Health Organization(WHO)have been detected in 99.9%of the *** results show that arsenic content ranged from 3.31 to 191 mg/l,with 99.9%of the samples exceeding the World Health Organization's safe limit of 10 mg/*** CR and CI exceeded the USEPA limit of 10–6 in all four tehsils ranged from 2.6×10^(-6) to 9.4×10^(-6) and 0.00023 to 0.0009 respectively in both dermal and oral cases.,Multan Sadar(1.51,1.39)and Multan City(1.76,1.71)exhibited HI and HQ values that surpassed the threshold of 1.0,signaling a significant likelihood of chronic and cancer-causing health consequences for individuals who are exposed to polluted water causing *** findings suggest that the groundwater in the Multan district poses a significant health risk to humans due to high levels of arsenic *** contamination is associated with an increased risk of mortality from internal cancers(including liver,kidney,lung,and bladder),as well as a higher HI&CI incidence of skin ***,pregnancy outcomes are affected,with associations found between arsenic exposure and lower birth weight,and infant *** researchers propose that water supply organizations and educational institutions promptly take measures to ensure that the affected areas have access to arsenic-free drinking water for the well-being of students and residents.

关键词： Risk assessment Drinking water contamination Arsenic Primary school Pakistan

Contrast Normalization Strategies in Brain Tumor Imaging:From Preprocessing to Classification

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Computer Modeling in Engineering & Sciences 2024年第8期140卷 1539-1562页

作者： Samar M.Alqhtani Toufique A.soomro Faisal Bin Ubaid ahmed Ali Muhammad Irfan Abdullah A.Asiri Department of Information Systems College of Computer Science and Information SystemsNajran UniversityNajran61441Saudi Arabia Department of Electronic Engineering The University of LarkanoLarkanaSindh75660Pakistan Computer Science Department Sukkur IBA UniversitySukkurSindh65200Pakistan Eletrical Engineering Department Sukkur IBA UniversitySukkurSindh65200Pakistan Electrical Engineering Department College of EngineeringNajran UniversityNajran61441Saudi Arabia Radiological Sciences Department College of Applied Medical SciencesNajran UniversityNajran61441Saudi Arabia

Cancer-related to the nervous system and brain tumors is a leading cause of mortality in various *** resonance imaging(MRI)and computed tomography(CT)are utilized to capture brain *** plays a crucial role in the diagnosis of brain tumors and the examination of other brain ***,manual assessment of MRI images by radiologists or experts is performed to identify brain tumors and abnormalities in the early stages for timely ***,early diagnosis of brain tumors is intricate,necessitating the use of computerized *** research introduces an innovative approach for the automated segmentation of brain tumors and a framework for classifying different regions of brain *** proposed methods consist of a pipeline with several stages:preprocessing of brain images with noise removal based on Wiener Filtering,enhancing the brain using Principal Component Analysis(PCA)to obtain well-enhanced images,and then segmenting the region of interest using the Fuzzy C-Means(FCM)clustering technique in the third *** final step involves classification using the Support Vector Machine(SVM)*** classifier is applied to various types of brain tumors,such as meningioma and pituitary tumors,utilizing the Contrast-Enhanced Magnetic Resonance Imaging(CE-MRI)*** proposed method demonstrates significantly improved contrast and validates the effectiveness of the classification framework,achieving an average sensitivity of 0.974,specificity of 0.976,accuracy of 0.979,and a Dice Score(DSC)of ***,this method exhibits a shorter processing time of 0.44 s compared to existing *** performance of this method emphasizes its significance when compared to state-of-the-art methods in terms of sensitivity,specificity,accuracy,and *** enhance the method further in the future,it is feasible to standardize the approach by incorporating a set of classifiers to increase the robustness of the brain classi

关键词： Brain tumor magnetic resonance imaging principal component analysis fuzzy c-clustering support vector machine

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影响MAX相合成及其性能的因素（英文）

Science China Materials 2024年第11期67卷 3427-3455页

作者： Maaz Ullah Khan Sumair ahmed soomro Muhammad Irfan Jahanger 周延春楚珑晟冯庆国胡春峰 Key Laboratory of Advanced Technologies of Materials Ministry of EducationSchool of Materials Science and EngineeringSouthwest Jiaotong University School of Materials Science and Engineering Zhengzhou University

MAX相是一类三元化合物,具有层状晶体结构和混合化学键性质(共价-离子-金属键),因而其同时具有陶瓷和金属的特性.MAX相陶瓷展现出与其他传统陶瓷不同的独特性能.在本综述中,我们重点介绍了一些代表性的MAX相合成方法,这些方法具有成本... 详细信息

MAX相是一类三元化合物,具有层状晶体结构和混合化学键性质(共价-离子-金属键),因而其同时具有陶瓷和金属的特性.MAX相陶瓷展现出与其他传统陶瓷不同的独特性能.在本综述中,我们重点介绍了一些代表性的MAX相合成方法,这些方法具有成本效益和节能潜力.MAX相的纯度、杂质相的形成、微观结构和性能在制备过程中受到许多参数的影响.因此,我们特别强调了各种因素的影响,这些因素会交替削弱材料的制备效率和最终性能.本文总结了起始材料、化学计量比、温度、压力、粒度、孔隙率、微观结构、机械合金化、机械活化、离子辐照和掺杂等多个参数的影响,以揭示它们对MAX相合成和性能的影响.最后,我们探讨了MAX相在商业上的潜在应用,并展望其在工业领域的发展前景.

关键词： MAX phase ceramics synthesis route properties applications

Effects of Velocity-slip on the Flow and Heat Transfer of a Two- Dimensional Stagnation-point Flow Towards a Porous Stretching Sheet with Heat Generation/absorption

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Effects of Velocity-slip on the Flow and Heat Transfer of a ...

作者： soomro Feroz ahmed（苏莫）南京大学

学位级别：硕士

本文研究了作用在流上的两种速度滑移线(一阶速度滑移线及二阶速度滑移线)效应以及作用在不同可延展表面上二维滞点流的热传输效应。针对该问题的研究在工程应用领域具有重要意义,并已成为近期的热门研究方向。本文工作可分为四个部分... 详细信息

本文研究了作用在流上的两种速度滑移线(一阶速度滑移线及二阶速度滑移线)效应以及作用在不同可延展表面上二维滞点流的热传输效应。针对该问题的研究在工程应用领域具有重要意义,并已成为近期的热门研究方向。本文工作可分为四个部分。其中,第一部分用于介绍背景知识以及已有的基础研究文献。在第二部分,我们引入了描述该问题的数学模型,根据速度滑移线以及延展表面类型的不同,可将该问题分为三种场景。第三部则介绍离散方法及数值求解过程。数值结论和相关细节讨论在放在第四部分。本文引用的所有文献则见于文章末尾的附录部分。

关键词：可伸展板多孔介质相似变化打靶法部分滑移

Bioinspired Multi-material Polyjet-printed Frog Robot for Synchronous and Asynchronous Swimming

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Journal of Bionic Engineering 2023年第3期20卷 923-933页

作者： Afaque Manzoor soomro Jae-Wook Lee Fida Hussain Memon Faheem ahmed Kashif Hussain Kyung Hyun Choi Department of Mechatronics Engineering Jeju National UniversityJeju63243South Korea Department of Electrical Engineering Sukkur IBA UniversitySukkur65200Pakistan

This paper proposes the bioinspired soft frog robot. All printing technology was used for the fabrication of the robot. Polyjet printing was used to print the front and back limbs, while ultrathin filament was used to print the body of the robot, which makes it a complete soft swimming robot. Dual thrust generation approach has been proposed by embedding the main muscle and antagonistic muscle in all the limbs, which enables it to attain high speed (18 mm/s), significant control to swim in dual mode (synchronous and asynchronous modes). To achieve the swimming motion of frog, four SMA (BMF 300) muscle wires were used. The frog robot is named as (FROBOT). The hind limbs are 60 mm long and 10 mm thick on average, while the front limbs are 35 mm long and 7 mm thick. Model-based design and rigorous analysis of the dynamics of real frogs have allowed FROBOT to be developed to swim at a level that is remarkably consistent with real frogs. Electrical and mechanical characteristics have been performed. In addition, the test data were further processed using TRACKER to analyze angle, displacement and velocity. FROBOT (weighs 65 g) can swim at different controllable frequencies (0.5–2 Hz), can rotate in any direction on command from custom built LabVIEW software allowing it to swim with speed up to 18 mm/s on deep water surface (100 cm) with excellent weight balance.

关键词： Bioinspired Soft robotics Frog FROBOT Asynchronous swimming

Optimization of chanterelle mushroom drying kinetics under heat pump dryer using Taguchi design method

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International Journal of Agricultural and Biological Engineering 2023年第6期16卷 273-279页

作者： Peter Mecha Rui Zhu Jiayu Zhang Emmanuel Awuah Shakeel ahmed soomro Kunjie Chen College of Engineering Nanjing Agricultural UniversityNanjing 210031China Department of Farm Structures Sindh Agriculture UniversityTandojam 70060Pakistan

The optimum drying conditions with regard to minimum color changes, high rehydration ratio and drying rate for chanterelle mushrooms is inadequately known. To address this problem, drying kinetics for chanterelle mushroom samples with sizes of 20 mm×20 mm×20 mm cube, 20 mm×20 mm×30 mm cuboid, and Ø40 mm×20 mm cylindrical shape were experimented. Drying air temperatures of 40℃, 48℃, and 56℃ at superfluous humidity and velocity of 2.2 m/s were used. Initial color pixels for each sample were determined using Note 8 Pro Xiaomi smartphone camera and image processing tool in Matlab R2019a. Triplicate experimentation was done based on L9 Taguchi orthogonal arrays with drying rate, specific moisture extraction rate, color change, and rehydration ratio being the response parameters. The drying rate increased from 1.1174 g/g∙min to 1.3478 g/*** as the temperature rose from 40℃ to 56℃. The mushroom cube had the highest drying rate of 1.2860 g/g∙min while the cylindrical shape had the lowest rate of 1.1764 g/g∙min. Similarly, SMER increased from 0.006 326to 0.013 27 g/kWh with the temperature rise. Contrary, SMER decreased from 0.006 92 to 0.013 63 g/kWh in cylinder to cube respectively. Color change was highest at 40℃ (13.49) and lowest at 56℃ (11.94). The mushroom cube had the lowest color change of 9.28 on average when compared to other shapes. Rehydration ratio was highest at 56℃ (3.824) as compared to 48℃ and 40℃. Additionally, the mushroom cube had the highest rehydration ratio of 4.55 on average as compared to other shapes. Temperature variation significantly influenced the drying rate and SMER. However, temperature variation had insignificant differences in color change and rehydration ratio. Mushroom shape variation had a significant difference in all the response variables tested. Conclusively, mushroom cubes at the drying temperature of 56℃ gave optimized drying conditions for chanterelle mushrooms with minimal quality deviations. Thus, chanterelle mushrooms can be

关键词： optimization chanterelle mushrooms drying kinetics heat pump dryer Taguchi design