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特区经济 2008年第10期 88-89页

作者：常爱新焦作师范高等专科学校

建国至今,我国的黄金管理体制经历了一个从"统购统配"到逐步放开黄金市场的过程。在这个过程中,黄金管理体制经历了一系列的改革,并且对社会发展和人民生活产生了重要影响。

关键词：黄金管理体制统购统配开放

In vivo degradation and endothelialization of an iron bioresorbable scaffold

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Bioactive Materials 2021年第4期6卷 1028-1039页

作者： Wenjiao Lin Hongjie Zhang Wanqian Zhang Haiping Qi Gui Zhang jie Qian xin Li Li Qin Haifeng Li Xiang Wang Hong Qiu Xiaoli Shi Wei Zheng Deyuan Zhang Runlin Gao Jiandong Ding College of Materials Science and Chemical Engineering Harbin Engineering UniversityHarbin 150001China Biotyx Medical(Shenzhen)Co. LtdShenzhen 518109China State Key Laboratory of Molecular Engineering of Polymers Department of Macromolecular ScienceFudan UniversityShanghai 200438China Shenzhen Advanced Medical Services Co. LtdShenzhen518000GuangdongChina Department of Cardiology Fuwai HospitalNational Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100037China Key Laboratory of Advanced Technology for Materials of Education Ministry School of Materials Science and EngineeringSouthwest Jiaotong UniversityChengdu 610031China

Detection of in vivo biodegradation is critical for development of next-generation medical devices such as bioresorbable stents or scaffolds(BRSs).In particular,it is urgent to establish a nondestructive approach to examine in vivo degradation of a new-generation coronary stent for interventional treatment based on mammal experiments;otherwise it is not available to semi-quantitatively monitor biodegradation in any clinical ***,we put forward a semi-quantitative approach to measure degradation of a sirolimus-eluting iron bioresorbable scaffold(IBS)based on optical coherence tomography(OCT)images;this approach was confirmed to be consistent with the present weight-loss measurements,which is,however,a destructive *** IBS was fabricated by a metal-polymer composite technique with a polylactide coating on an iron *** efficacy as a coronary stent of this new bioresorbable scaffold was compared with that of a permanent metal stent with the name of trade mark Xience,which has been widely used in *** endothelial coverage on IBS was found to be greater than on Xience after implantation in a rabbit model;and our well-designed ultrathin stent exhibited less individual *** further examined degradation of the IBSs in both minipig coronary artery and rabbit abdominal aorta *** present result indicated much faster iron degradation of IBS in the rabbit model than in the porcine *** semi-quantitative approach to detect biodegradation of IBS and the finding of the species difference might be stimulating for fundamental investigation of biodegradable implants and clinical translation of the next-generation coronary stents.

关键词： Iron bioresorbable scaffold Species difference Endothelialization In vivo biodegradation Optical coherence tomography

Optimization of sgRNA expression strategy to generate multiplex gene-edited pigs

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Zoological Research 2022年第6期43卷 1005-1008页

作者： Ju-Qing Zhang Jian-Xiong Guo Xiao-jie Wu Yu Wang Wei Yue Zhuo-Hui Li Wei Wang xin-Fang Wei Xiao-Long Wu Qiao-Yan Shen An-Min Lei Hong-Jiang Wei Jin-Lian Hua College of Veterinary Medicine Shaanxi Centre of Stem Cells Engineering&TechnologyNorthwest A&F University State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan Yunnan Agricultural University College of Animal Sciences&Technology Northwest A&F University National Institute of Biological Sciences

DEAR EDITOR,The use of CRISPR/Cas9 technology to breed polygenicmodified animals with desired traits holds great promise in agriculture and biomedicine. However, as most studies are based on human and mouse models, whether different single guide RNA(sg RNA) expression strategies affect multiplex gene-editing efficiency in domestic animals remains elusive.

关键词： CRISPR/Cas9 holds desired

ADOMN： Asymmetric-Path Delay Optimization in Mobile Network for multi-homing SCTP multimedia transport

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通讯和计算机（中英文版） 2007年第7期4卷 27-32页

作者： LIU jie-min Bai Yu DOU Jing-xin ZOU Hong-xing GAO Yuan Department of Computer Engineering Northeastern University at Qinhuangdao Qinhuangdao 066004 China

Multimedia applications, in particular real-time conversations with voice or video are very demanding of network quality parameters, especially in a mobile wireless scenario. End-to-End delay is a primary concern for mobile multi-homed SCTP multimedia transport, especially asymmetric path selection based on lowest delay. Using the emulated application of bulk data transfer, existing transport schemes based on asymmetric path delay selection are investigated and a new approach called Asymmetric-path is presented Delay Optimization in Mobile Network (ADOMN) based on lowest delay path taking into account the dynamic asymmetric over the available routes to reduce the limitation of existing scheme and to further improve the performance of mobile multi-homed SCTP multimedia transport. An example is provided to show how a mutlimedia application in mobile network could benefit from this approach

关键词：移动网络不对称路径延迟最优化多媒体应用 SCTP

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身体功能训练团队的实践探索及发展反思

体育科学 2014年第2期34卷 79-86页

作者：王雄刘爱杰国家体育总局训练局体能训练中心北京100061 清华大学体育部北京100084 国家体育总局竞技体育司北京100061

在当前世界竞技体育职业化和商业化的深刻背景下,高强度、密集型的赛制模式对运动员的体能水平提出了新要求,促进了传统体能训练方法的发展和演变。近年来,美国职业体育的繁荣催生出体能训练理论和实践领域的新发展,中国奥委会在备战伦... 详细信息

在当前世界竞技体育职业化和商业化的深刻背景下,高强度、密集型的赛制模式对运动员的体能水平提出了新要求,促进了传统体能训练方法的发展和演变。近年来,美国职业体育的繁荣催生出体能训练理论和实践领域的新发展,中国奥委会在备战伦敦奥运会周期与美国具有代表性的AP训练机构合作,进行了身体功能训练团队工作的实践,给中国国家队带来了新的训练理念和方法体系。介绍了团队工作中FMS测试、物理治疗、身体功能训练三项主体实践内容,对其中揭示的问题进行重点解析,对国家队的整体实践探索过程进行述评;对当前国内体能训练领域的阶段定位、人才培养机制及行业协会发展、批判继承和创建自主特色的训练体系等方面进行反思,并提出相关针对性建议。

关键词：身体功能训练团队 AP 训练体系实践探索发展反思

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郏县红牛线粒体全基因组测序及结构特征分析

河南城建学院学报 2024年第4期33卷 114-119页

作者：陈艳艳郭婧郭银龙艾付镇高瑞阳李梦婷赵萌臻白钢锋叶延欣河南城建学院生命科学与工程学院河南平顶山467036 平顶山市瑞宝红牛有限公司河南平顶山467036

郏县红牛是我国八大优良黄牛品种之一,是当地一个役肉兼用的优良品种。利用高通量测序技术对郏县红牛全线粒体基因组进行测序,并对其特征进行分析。结果显示:郏县红牛全线粒体基因组全长16 339 bp,共注释到37个基因(包含13个蛋白编码基... 详细信息

郏县红牛是我国八大优良黄牛品种之一,是当地一个役肉兼用的优良品种。利用高通量测序技术对郏县红牛全线粒体基因组进行测序,并对其特征进行分析。结果显示:郏县红牛全线粒体基因组全长16 339 bp,共注释到37个基因(包含13个蛋白编码基因、22个tRNA、2个rRNA)和一个控制区域(D-loop),无内含子区域,但有重叠基因,A+T含量为60.6%,存在明显的AT偏向性。基因组序列中共存在13个基因间隔区域,最长为16 bp,位于NADH5与NADH6之间;同时存在4个基因重叠,最长为33 bp,位于tRNA-Gln与tRNA-Met之间。其中9个基因位于轻链,26个基因位于重链。郏县红牛线粒体基因组序列的解析有助于丰富其线粒体基因组资源,同时为郏县红牛的种质资源保护和遗传育种提供重要的基础。

关键词：郏县红牛全线粒体DNA 高通量测序基因

有质动力和静电分离场对激光等离子体流体力学状态的影响

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物理学报 2005年第2期54卷 812-817页

作者：苍宇鲁欣武慧春张杰中国科学院物理研究所光物理重点实验室北京100080

利用建立在欧拉坐标系上的一维电子_离子双流双温流体力学程序 ,模拟了超短脉冲强激光 (1× 10 1 5W cm2 ,15 0fs)与线性密度梯度等离子体相互作用的流体力学过程 .模拟结果显示 ,入射激光与临界密度面的反射光叠加 ,在临界密度以下区... 详细信息

利用建立在欧拉坐标系上的一维电子_离子双流双温流体力学程序 ,模拟了超短脉冲强激光 (1× 10 1 5W cm2 ,15 0fs)与线性密度梯度等离子体相互作用的流体力学过程 .模拟结果显示 ,入射激光与临界密度面的反射光叠加 ,在临界密度以下区域形成局域驻波 ,产生的强有质动力在低密区驱动电子形成周期性密度结构———Bragg光栅 ,激光的反射被增强 .临界密度处有质动力将等离子体分成向内和向外运动的两部分 .由于离子所受的有质动力和热压强的梯度力远小于电子 ,体系产生了强静电分离场 ,离子的运动主要由该静电分离场决定 .对双流双温模型和单流双温模型的模拟结果进行了比较 .当有质动力和热压强梯度力较大时 ,两种模型对等离子体流体力学状态的描述有明显差异 ,单流双温模型无法描述此时的流体力学状态 .

关键词：有质动力临界密度流体力学静电分离电子激光等离子体梯度力 Bragg光栅超短脉冲强激光状态

Characteristics and Degradation Mechanism of Fomesafen

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Journal of Northeast Agricultural University(English Edition) 2018年第1期25卷 9-15页

作者： Tao Bo Qiao Yu-xin Ma Cheng-yi Shao Bai-hui jie Bai College of Agricultural Northeast Agricultural University

High performance liquid chromatography(HPLC) was used to determine the degradation efficiency of bacteria 2 strain(B2 S) under different conditions, the optimum cultivation conditions for fomesafen degradation bacterium B2 S were as the followings: temperature 35℃; inoculation quantity 5%; p H 5.0; glucose content 0.5% and fomesafen concentration 10 mg · L-1. Under optimal conditions, B2 S degraded fomesafen within 72 h of fomesafen application, with a degradation rate of nearly 100%. High performance liquid chromatography-mass spectrometry(HPLC-MS) was used to analyze fomesafen degradation into microbial products. A more thorough understanding of microbial fomesafen degradation mechanisms was discussed. The pathway of fomesafen degradation by B2 S was also inferred herein.

关键词： fomesafen bacteria 2 strain(B2S) degradation rate degradation product

新文化运动到抗日战争爆发前河北省女性教育的发展特征

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河北师范大学学报（教育科学版） 2010年第11期12卷 72-75页

作者：徐爱新河北大学教育学院河北保定071002

20世纪二三十年代,河北省的女性教育迎来了一个稳定发展时期,妇女解放思想教育成为这一时期女性思想教育的主题。女子学校在层次和类别上呈多样性发展,形成了较完整的教育体系;兴起了有组织、较规范的女子社会教育;留法勤工俭学活动促... 详细信息

20世纪二三十年代,河北省的女性教育迎来了一个稳定发展时期,妇女解放思想教育成为这一时期女性思想教育的主题。女子学校在层次和类别上呈多样性发展,形成了较完整的教育体系;兴起了有组织、较规范的女子社会教育;留法勤工俭学活动促使河北女性迈出了走出国门的第一步。

关键词：女子教育河北省女性教育女子学校

XB130 Knockdown Inhibits the Proliferation, Invasiveness, and Metastasis of Hepatocellular Carcinoma Cells and Sensitizes them to TRaiL-Induced Apoptosis

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Chinese Medical Journal 2018年第19期131卷 2320-2331页

作者： Guang-Ming Li Chao-jie Liang Dong-xin Zhang Li-Jun Zhang Ji-Xiang Wu Ying-Chen Xu Department of General Surgery Beijing Tongren Hospital Capital Medical University Beijing 100730 China Department of General Surgery First Hospital/First Clinical Medical College of Shanxi Medical University Taiyuan Shanxi 030001 China

Background：XB 130 is a recently discovered adaptor protein that is highly expressed in many malignant tumors,but few studies have investigated its role in hepatocellular carcinoma （HCC）.Therefore,this study explored the relationship between this protein and liver cancer and investigated its molecular mechanism of ***：The expression of XB 130 between HCC tissues and adjacent nontumor tissues was compared by real-time polymerase chain reaction,immunochemistry,and Western ***130 silencing was performed using small hairpin *** effect of silencing XB130 was examined using Cell Counting Kit-8,colony assay,wound healing assay,and cell cycle ***：We found that XB 130 was highly expressed in HCC tissues （cancer tissues *** tissues：0.23 ± 0.02 vs.0.17 ± 0.02,P 〈 0.05） and liver cancer cell lines,particularly MHCC97H and HepG2 （MHCC97H and HepG2 *** liver cell line LO-2：2.35 ± 0.26 and 2.04 ± 0.04 vs.1.00 ± 0.04,respectively,all P 〈 0.05）.The Cell Counting Kit-8 assay,colony formation assay,and xenograft model in nude mice showed that silencing XB130 inhibited cell proliferative ability both in vivo and in vitro,with flow cytometry demonstrating that the cells were arrested in the G0/G1 phase in HepG2 （HepG2 XB130-silenced group [shA] ***2 scramble group [NA]：74.32 ± 5.86% vs.60.21 ± 3.07%,P 〈 0.05） and that the number of G2/M phase cells was decreased （HepG2 shA ***2 NA：8.06 ± 2.41% vs.18.36 ± 4.42%,P 〈 0.05）.Furthermore,the cell invasion and migration abilities were impaired,and the levels of the epithelial-mesenchymal transition-related indicators vimentin and N-cadherin were decreased,although the level of E-cadherin was increased after *** blotting showed that the levels of phosphorylated phosphoinositide 3-kinase （PI3K） and phospho-protein kinase B （p-Akt） also increased,although the level of phosphorylated phosphatase and tensin homolog increased,indicating that XB 130 activated the PI3K/ Akt pa

关键词： Apoptosis Hepatocellular Carcinoma PI3K/Akt TRaiL XB 130