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Development of an ultrathin liquid sheet target for laser ion acceleration at high repetition rates in the kilohertz range

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High Power laser Science and Engineering 2024年第3期12卷 134-145页

作者： M.Füle A.P.Kovács T.gilinger M.Karnok P.gaál S.Figul g.Marowsky K.Osvay National laser-Initiated Transmutation laboratory University of SzegedSzegedHungary Department of Experimental Physics University of SzegedSzegedHungary ElI AlPS ELI-HU Non-Profit Ltd.SzegedHungary Department of Optics and Quantum Electronics University of SzegedSzegedHungary Advanced Microfluidic Systems gmbH GöttingenGermany

A colliding microjet liquid sheet target system was developed and tested for pairs of round nozzles of 10,11 and 18μm in *** sheet's position stability was found to be better than a few *** interaction with 50 mJ laser pulses,the 18μm jet has a resonance amplitude of 16μm at a repetition rate of 33 Hz,while towards 100 Hz it converges to 10μm for all nozzles.A white-light interferometric system was developed to measure the liquid sheet thickness in the target chamber both in air and in vacuum,with a measurement range of 182 nm±1μm and an accuracy of±3%.The overall shape and 3D shape of the sheet follow the Hasson±Peck model in *** vacuum versus air,the sheet gradually loses 10%of its thickness,so the thinnest sheet achieved was below 200 nm at a vacuum level of 10±4mbar,and remained stable for several hours of operation.

关键词： diagnostics laser ion acceleration nanometric liquid sheet targets vacuum test

Newly identified Au-Ag-Bi-Te mineralization in the Aydindere skarn Fe and Cu deposit， giresun， NE Turkey: implications of gold mineralization during retrograde skarn evolution

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Journal of Earth Science 2024年

作者： ahmet Sasmaz Vitaliy Sukach Serhiy Bondarenko Hryhorii Aleksiienko Hengameh Erfanian Kaseb Bilge Sasmaz Sergiy Kurylo Oleksandr Hrinchenko Volodymyr Somka Panagiotis Voudouris Department of geology， Firat University Faculty of geology and geoenvironment， National and Kapodistrian University of Athens Mineralogy and Ore Formation of National Academy of Science， M.P.Semenenko Institute of geochemistry 3. Department of Petroleum Engineering， Eqbal lahoori Institute of Higher Education

This study investigates the mineralogy and mineral-chemistry of a newly discovered Au-Ag-Bi-Te mineralization at the Aydindere Fe-Cu skarn deposit， within the Pontides Tectonic Unit， northeastern Turkey. The mineralization is developed in the skarn zone at the contact between Upper Cretaceous andesite-pyroclastic rocks and a Paleocene-Eocene I-type granitoid. The principal ore minerals of the Aydindere Fe-Cu deposit are oxides (magnetite)， sulfides (pyrite-chalcopyrite-galena-sphalerite)， tellurides/sulfotellurides (tetradymite， hessite)， sulfosalts (wittichenite， emplectite， aikinite) and native gold-electrum. Skarn minerals include anhydrous phases (garnet) formed in a prograde stage and hydrous phases (amphibole， epidote， chlorite)， which were formed in a retrograde stage in association with quartz， adularia， apatite and late calcite. Sulfides， tellurides and sulfosalts are introduced during the retrograde stage. The Au-Ag-Bi-Te mineralization was detected for the first time within the western ore body of the Aydindere deposit， and occurs in calcite-bearing sulfide bodies that cut magnetite-garnet-amphibole-epidote skarns with magnetite ores of different grade， including massive magnetite. Chlorite geothermometry indicates formation of the Au-Ag-Bi-Te mineralization at temperatures between 300 and 250 °C， during the retrograde skarn evolution. Assuming the temperature is ～275°C， logfS2= -10.5 to -13， logfO2= -37 to -33， and logfTe2values range from approximately -12 to -8.5 were estimated. The available mineralogical and geological data (presences of magnetite， oxidized-type tellurides/sulfotellurides， and andraditic garnets， and absence of pyrrhotite and arsenopyrite) suggest that Aydindere is an oxidized Au-bearing skarn deposit. The discovery of Au-Ag-Bi-Te mineralization at Aydindere increases its productivity and requires more detailed exploration in the deposit for precious (Au， Ag) and critical (Bi， Te) metals.

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Degradation and resynthesis of chlorophyll during increased oxidative stress and prolonged darkness differ between annual and perennial flax(linum l.)

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Oil Crop Science 2024年第2期9卷 121-130页

作者： Kenyon J. Nisbett Abida Alokozai Su Hyun Elizabeth Ko g. Adam Mott Jason C.l. Browna Department of Biological Sciences University of Toronto ScarboroughTorontoONCanada Department of Cell&Systems Biology University of TorontoTorontoONCanada Centre for the Analysis of genome Evolution&Function University of TorontoTorontoONCanada

Among plants,there is considerable variation in lifespan:annuals live less than one year,whereas perennials live for several years,with the longest-living perennial having survived 43,600 *** proposed by the Disposable Soma Theory,this lifespan variation among plants likely reflects differential investment of limited energy and nutrient resources,with perennials investing more energy and nutrients into biomolecular maintenance compared to annuals in order to ensure persistence over multiple *** differential investment may be particularly important during periods of exogenous stress,which are known to accelerate biomolecular *** present study evaluated this hypothesis using annual and perennial flax(linum l.)subjected to two exogenous stressors—increased oxidative stress(i.e.,foliar H2O2spraying)and complete prolonged *** chlorophyll has been shown to exhibit degradation in response to changes in environmental conditions,we utilized changes in chlorophyll levels during and after periods of exogenous stress to evaluate our *** predicted that i)perennials would exhibit a slower rate of chlorophyll degradation during exposure to exogenous stressors compared to annuals,and ii)perennials would exhibit a faster rate of chlorophyll resynthesis following such exposure compared to *** levels before,during,and after exposure to both exogenous stressors were measured in two separate trails,once using image colour analysis and once using *** chlorophyll degradation rates in response to oxidative stress did not differ between annuals and perennials,contrary to our predictions,chlorophyll resynthesis rates following such exposure were significantly higher in perennials,as *** plants were subjected to complete prolonged darkness,chlorophyll degradation rates were significantly lower in perennials than annuals,as predicted;however,when plants were subsequently reintroduced to natural photoperiod,ch

关键词： Ageing life history Maximum lifespan Oxidative stress Somatic maintenance

Shell-model representations of the microscopic version of the Bohr-Mottelson collective model

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Communications in Theoretical Physics 2024年第8期76卷 79-90页

作者： H g ganev Joint Institute for Nuclear Research DubnaRussia Institute of Mechanics Bulgarian Academy of SciencesSofiaBulgaria

The structure of the irreducible collective spaces of the group Sp(12,R),which many-particle nuclear states are classified according to the chain Sp(12,R)⊃U(6)⊃SO(6)⊃SU_(pn)(3)⊗SO(2)⊃SO(3)of the proton-neutron symplectic model(PNSM),is considered in *** chain of the PNSM was recently shown to correspond to a microscopic shell-model version of the Bohr-Mottelson collective *** construction of the relevant shell-model representations of the Sp(12,R)group along this chain is considered for three nuclei with varying collective properties and from different mass *** is shown that the SU_(pn)(3)basis states of the Sp(12,R)representations belonging to the SO(6)irreps with seniorityυ≥υ0,withυ0 denoting the maximal seniority SO(6)irrep contained in the Sp(12,R)bandhead,are always Pauli allowed,but organized in a different way into different SO(6)*** is in contrast to the case of filling the levels of the standard three-dimensional harmonic oscillator and using the plethysm *** the SU_(pn)(3)multiplets withinυll Pauli forbidden,it is safe to discard *** results obtained in the present work are important for the practical application of the microscopic version of the Bohr-Mottelson collective model.

关键词： microscopic shell-model version of the Bohr-Mottelson model proton-neutron symplectic model Sp(12,R)dynamical algebra shell-model representations

Dynamics and cytokinic regulation of immune cell infiltration in genetically engineered mouse models of pancreatic cancer dictate the sensitivity to immunotherapy

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Cancer Communications 2024年第1期44卷 178-182页

作者： Okan Safak Shenghan Wang Carmen Mota Reyes Ibrahim Halil gürcinar Sergey Tokalov Nedim Can Cevik Kivanc görgülü Bengi Su Yilmaz Emre Erdogan linhan Ye Qiaolin li Elif Arik Sever SamedÖzer güldal Süyen Helmut Friess güralp Onur Ceyhan Rouzanna Istvanffy Hana Algül Ihsan Ekin Demir Department of Surgery Klinikum rechts der IsarTechnical University of MunichSchool of MedicineMunichBavariaGermany Department of general Surgery HPB-UnitSchool of MedicineAcibadem Mehmet Ali Aydinlar UniversityIstanbulIstanbulTurkey Comprehensive Cancer Center München Klinikum rechts der IsarTechnical University of MunichSchool of MedicineMunichBavariaGermany Department of Hematology Oncology and Tumor ImmunologyCharitéUniversity Medicine BerlinCampus Virchow ClinicBerlinBerlinGermany graduate School of Health Sciences Acibadem Mehmet Ali Aydinlar UniversityIstanbulIstanbulTurkey Department of Physiology Acibadem Mehmet Ali Aydinlar UniversityIstanbulIstanbulTurkey Else Kröner Clinician Scientist Professorship for Translational Pancreatic Surgery MunichGermany Neural Influences in Cancer(NIC)International Research Consortium MunichGermany

Dear Editor,Targeting the immune compartment in pancreatic duc-tal adenocarcinoma(PDAC)holds promise for prognostic improvement,yet our knowledge on the spatial and tem-poral dynamics and the molecular modulators of t... 详细信息

关键词： immune adenocarcinoma immunotherapy

Harmonics in the Squirrel Cage Induction Motor Analytic Calculation Part III: Influence on the Torque-speed Characteristic

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CES Transactions on Electrical Machines and Systems 2024年第1期8卷 86-102页

作者： g.Kovács the ganz Electric Works BudapestHungary

The harmonics that appear in the squirrel cage asynchronous machine have been discussed in great detail in the literature for a long time. However, the systematization of the phenomenon is still pending, so we made an attempt to fill this gap in the previous parts of our study by elaborating formulas for calculation of parasitic torques. It was a general demand among those who work in this field towards the author to verify his formulas with measurements. In the literature, it seems,only one detailed, purposeful series of measurements has been published so far, the purpose of which was to investigate the effect of the number of rotor slots on the torque-speed characteristic curve of the machine. The main goal of this study is to verify the correctness of the formulas by comparing them with the referred series of measurements. Relying on this, the expected synchronous parasitic torques were developed for the frequently used rotor slot numbers-as a design guide for the ***, together with our complete table for radial magnetic pull published in our previous work, the designer has all the principles, data and formulas available for the right number of rotor slots for his given machine and for the drive system. This brings this series of papers to an end.

关键词： Asynchronous parasitic torques Induction motor Squirrel cage rotor Space harmonics Synchronous parasitic torques

On the functions of astrocyte-mediated neuronal slow inward currents

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Neural Regeneration Research 2024年第12期19卷 2602-2612页

作者： Balázs Pál Department of Physiology Faculty of MedicineUniversity of DebrecenDebrecenHungary

Slow inward currents are known as neuronal excitatory currents mediated by glutamate release and activation of neuronal extra synaptic N-met hyl-D-aspartate receptors with the contribution of *** events are significantly slower than the excitatory postsynaptic *** of slow inward currents are determined by seve ral factors including the mechanisms of astrocytic activation and glutamate release,as well as the diffusion pathways from the release site towards the extra synaptic recepto *** are stimulated by neuronal network activity,which in turn excite neurons,forming an astrocyte-neuron feedback *** as a consequence of brain edema,astrocytic swelling can also induce slow inward currents under pathological *** is a growing body of evidence on the roles of slow inward currents on a single neuron or local network *** events often occur in synchro ny on neurons located in the same astrocytic *** synchronization of neuronal excitability,slow inward currents also set synaptic strength via eliciting timing-dependent synaptic *** addition,slow inward currents are also subject to non-synaptic plasticity triggered by long-la sting stimulation of the excitatory *** note,there might be important regionspecific differences in the roles and actions triggering slow inward *** greater networks,the pathophysiological roles of slow inward currents can be better understood than physiological *** inward currents are identified in the pathophysiological background of autism,as slow inward currents drive early hypersynchrony of the neural *** inward currents are significant contributors to paroxysmal depolarizational shifts/interictal *** events are related to epilepsy,but also found in Alzheimer's disease,Parkinson's disease,and stroke,leading to the decline of cognitive *** with features overlapping with slow inward currents(excitatory,N-methyl-Dasp

关键词： astrocyte cortical spreading depolarization gliotransmission glutamate neural synchronization NMDA receptor paroxysmal depolarizational shift slow inward current

On calculating glacial isostatic adjustment

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geodesy and geodynamics 2024年第5期15卷 441-452页

作者： l.M.Cathles Cornell University IthacaNY 14853USA

Modeling the earth's fluid and elastic response to the melting of the glaciers of the last ice age is the most direct way to infer the earth's radial viscosity ***,we compare two methods for calculating the viscoelastic response to surface *** one,the elastic equation of motion is converted to a viscoelastic equation using the Correspondence *** the other,elastic deformation is added to the viscous flow as isostatic adjustment *** two modeling methods predict adjustment histories that are different enough to potentially impact the interpretation of the observed glacial isostatic adjustment(gIA).The differences arise from buoyancy and whether fluid displacements are subjected to hydrostatic *** methods agree if they use the same equations and boundary *** origin of the differences is determined by varying the boundary conditions and pre-stress application.

关键词： glacial isostatic adjustment Viscoelastic normal modes Hydrostatic pre-stress Elastic buoyancy Correspondence principle

Neuroimaging in atypical normal tension glaucoma:debating routine implementation in the absence of classic neurological findings

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International Journal of Ophthalmology(English edition) 2024年第3期17卷 509-517页

作者： Umay güvenç gülizar Demirok güner Üney Selma Uzman Ophthalmology Department Ankara Training and Research HospitalAnkara 06230Turkey

●AIM:To assess the necessity of neuroimaging in patients with neurological or atypical findings of normal tension glaucoma(NTg)who do not exhibit typical glaucoma manifestations.●METHODS:A retrospective analysis was conducted on 90 atypical NTg patients who underwent cranial magnetic resonance imaging(MRI)due to atypical *** demographic characteristics,clinical parameters,and radiological findings were recorded.●RESUlTS:Among the patients,66.7%had abnormal radiology results,with the most common findings being gliosis(34.4%),sequelae of cerebrovascular events and vascular malformations(14.4%),and benign intracranial mass lesions(11%).Non-glaucomatous visual field defects were more frequently observed in patients with abnormal neuroimaging ***,there were no significant differences in intraocular pressure,optic disc parameters,retinal nerve fiber layer thickness,and visual field indices between patients with normal and abnormal radiological *** mean age of the patients was ***,there was a significant age difference,with the abnormal radiology group having a higher median age(P=0.021).●CONClUSION:The study highlights the importance of cranial imaging in older NTg patients to detect underlying pathologies and prevent *** suggests that neuroimaging may be warranted in NTg patients with atypical visual field defects incompatible with ***,routine neuroimaging in all NTg patients without classic neurological signs may not be necessary.

关键词： normal tension glaucoma neuroimaging atypical visual field defects