检索结果-南通市图书馆

Neoadjuvant hyperfractionated accelerated radiotherapy plus concomitant 5-fluorouracil infusion in locally advanced rectal cancer: A phase Ⅱ study

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Oncology 2018年第1期10卷 40-47页

作者： Zeynep Gural sezer Saglam Serap Yucel Esra Kaytan-Saglam Oktar Asoglu Cetin Ordu Hediye Acun Rasul Sharifov Semen Onder ahmet Kizir Ethem N Oral Department of Radiation Oncology Acibadem University Medical Faculty Department of Medical Oncology Istanbul Bilim University Department of Radiation Oncology Istanbul Medical FacultyIstanbul University Department of General Surgery Academia of Clinical Science of Bogazici Department of Medical Biophysics Harran University Medical Faculty Department of Radiology Bezm-i AlemUniversity Department of Pathology Istanbul Medical FacultyIstanbul University

AIM To evaluate the efficacy and tolerability of neoadjuvant hyperfractionated accelerated radiotherapy(HART)and concurrent chemotherapy in patients with locally advanced infraperitoneal rectal cancer. METHODS A total of 30 patients with histopathologically confirmed T2-3/N0+ infraperitoneal adenocarcinoma of rectum cancer patients received preoperative 42 Gy/1.5 Gy/18 days/bid radiotherapy and continuous infusion of 5-fluorouracil(325 mg/m^2). All patients were operated 4-8 wk after neoadjuvant concomitant therapy. RESULTS In the early phase of treatment, 6 patients had grade Ⅲ-Ⅳ gastrointestinal toxicity, 2 patients had grade Ⅲ-Ⅳ hematologic toxicity, and 1 patient had grade Ⅴ toxicity due to postoperative sepsis during chemotherapy. Only 1 patient had radiotherapy-related late side effects, i.e., grade Ⅳ tenesmus. Complete pathological response was achieved in 6 patients(21%), while near-complete pathological response was obtained in 9(31%). After a median follow-up period of 60 mo, the local tumor control rate was 96.6%. In 13 patients, distant metastasis occurred. Disease-free survival rates at 2 and 5 years were 63.3% and 53%, and corresponding overall survival rates were 70% and 53.1%, *** Although it has excellent local control and complete pathological response rates, neoadjuvant HART concurrent chemotherapy appears to not be a feasible treatment regimen in locally advanced rectal cancer, having high perioperative complication and intolerable side effects. Effects of reduced 5-fluorouracil dose or omission of chemotherapy with the aim of reducing toxicity may be examined in further studies.

关键词： Hyperfractionated accelerated radiotherapy Rectal cancer Neoadjuvant chemoradiotherapy

Respiratory Mechanics, Respiratory Muscle Strength, Control of Ventilation and Gas Exchange in Patients with Autoimmune Liver Disease

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

New testing methodology for the quantification of rock crushability:Compressive crushing value(CCV)

Open Journal of Respiratory Diseases（呼吸病期刊） 2024年第2期 25页

作者： ahmet Baydur Jacob Korula

来源：博看期刊评论

在线全文

博看期刊

学校读者我要写书评

暂无评论

International Journal of Minerals,Metallurgy and Materials 2018年第11期25卷 1227-1236页

作者： Ekin Koken ahmet Ozarslan Department of Mining Engineering Zonguldak Bülent Ecevit University67100ZonguldakTurkey

Crushing is a size reduction process that plays a key role in both mineral processing and crushing–screening plant design. Investigations on rock crushability have become an important issue in mining operations and the manufacture of industrial crusher equipment. The main objective of this research is to quantify the crushability of hard rocks based on their mineralogical and mechanical properties. For this purpose, the mineralogical, physical, and mechanical properties of various hard rocks were determined. A new compressive crushing value(CCV) testing methodology was proposed. The results obtained from CCV tests were compared with those from mineralogical inspections, rock strength as well as mechanical aggregate tests. Strong correlations were found between CCV and several rock and aggregate properties such as uniaxial compressive strength(UCS), the brittleness index(S_(20)), and aggregate impact value(AIV). Furthermore, the relationship between the mineralogical properties of the rocks and their CCVs were established. It is concluded that the proposed testing methodology is simple and highly repeatable and could be utilized as a pre-design tool in the design stage of the crushing process for rock quarries.

关键词： crushability jaw crusher hard rocks aggregate rock strength crushed stone

Finite Element Analysis of the Contact Mechanics of Ceramic-on-Ceramic Hip Resurfacing Prostheses

在线全文

学校读者我要写书评

暂无评论

Journal of Bionic Engineering 2010年第3期7卷 244-253页

作者： ahmet C.Cilingir Department of Mechanical Engineering Sakarya University

Ceramics are good alternative to metal as bearing couple materials because of their better wear resistance. A Finite Element(FE) study was performed to investigate the contact mechanics and stress distribution of Ceramic-on-Ceramic (COC) hip resurfacingprostheses. It was focused in particular on a parametric study to examine the effects of radial clearance, loading,alumina coating on the implants, bone quality, and fixation of cup-bone interface. It was found that a reduction in the radialclearance had the most significant effect on the predicted contact pressure distribution among all of the parameters considered inthis study. It was determined that there was a significant influence of non-metallic materials, such as the bone underneath thebearing components, on the predicted contact mechanics. Stress shielding within the bone tissue was found to be a major concernwhen regarding the use of ceramic as an alternative to metallic resurfacing prostheses. Therefore, using alumina implantswith a metal backing was found to be the best design for ceramic resurfacing prostheses in this study. The loading, bone quality,and acetabular cup fixation conditions were found to have only minor effects on the predicted contact pressure distribution alongthe bearing surfaces.

关键词： contact mechanics hip resurfacing ceramic finite element analysis

Effect of Rotational and Sliding Motions on Friction and Degeneration of Articular Cartilage under Dry and Wet Friction

在线全文

学校读者我要写书评

暂无评论

Journal of Bionic Engineering 2015年第3期12卷 464-472页

作者： ahmet C. Cilingir Department of Mechanical Engineering Sakarya University 54187 Sakatya Turkey

Understanding the tribological properties of articular cartilage allows scientists to evaluate degenerative joint diseases and develop new treatment techniques. The objectives of this study are to demonstrate the detrimental effect of rotational motion under both dry and wet friction and to evaluate the friction and wear behavior of bovine articular cartilage with sliding and rotational testing configurations that represent fluid film and boundary lubrication mechanisms, respectively. The articular cartilage pin and plate samples were harvested from healthy adult bovine and then tested on a self-made friction and wear simulator. Cartilage samples were subjected to sliding and rotational motions under constant load. Friction coefficients and wear factors were calculated under three conditions： using bovine serum, phosphate buffered saline and with no lubricant present. The friction coefficient and wear factor of the articular cartilage were significantly increased with rotational motion under both dry and wet friction. Using bovine serum as lubricant in the sliding testing configuration the friction coefficient and wear factor of articular cartilage were both decreased. A similar decrease in the tribological properties of cartilage was initially observed for the rotational testing configuration with bovine serum; however, the friction coefficient and wear factor were increased after 150,000 cycles. In the absence of lubricant, the articular cartilage was entirely worn on contact area in both sliding and rotational testing configurations. Bovine serum proved an effective fluid film lubricant for articular cartilage surfaces.

关键词： articular cartilage rotational motion sliding motion dry friction wet friction wear

Bright and dark soliton solutions for some nonlinear fractional differential equations

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Physics B 2016年第3期25卷 52-59页

作者： Ozkan Guner ahmet Bekir Cankiri Karatekin University Faculty of Economics and Administrative Sciences Department of International Trade CankiriTurkey Eskisehir Osmangazi University Art-Science Faculty Department of Mathematics-Computer Eskisehir Turkey

In this work, we propose a new approach, namely ansatz method, for solving fractional differential equations based on a fractional complex transform and apply it to the nonlinear partial space-time fractional modified Benjamin-Bona- Mahoney （mBBM） equation, the time fractional mKdV equation and the nonlinear fractional Zoomeron equation which gives rise to some new exact solutions. The physical parameters in the soliton solutions： amplitude, inverse width, free parameters and velocity are obtained as functions of the dependent model coefficients. This method is suitable and more powerful for solving other kinds of nonlinear fractional PDEs arising in mathematical physics. Since the fractional deriva- tives are described in the modified Riemann-Liouville sense.

关键词： exact solutions ansatz method space-time fractional modified Benjamin-Bona-Mahoney equa-tion time fractional mKdV equation

Bound states resulting from interaction of the non-relativistic particles with the multiparameter potential

在线全文

学校读者我要写书评

暂无评论

Chinese Physics B 2017年第10期26卷 38-48页

作者： ahmet Tas Ali Havare Mersin University Department of Physics

In this study, we present the analytical solutions of bound states for the Schrodinger equation with the mulfiparameter potential containing the different types of physical potentials via the asymptotic iteration method by applying the Pekeristype approximation to the centrifugal potential. For any n and l （states） quantum numbers, we derive the relation that gives the energy eigenvalues for the bound states numerically and the corresponding normalized eigenfunctions. We also plot some graphics in order to investigate effects of the multiparameter potential parameters on the energy eigenvalues. Furthermore, we compare our results with the ones obtained in previous works and it is seen that our numerical results are in good agreement with the literature.

关键词： multiparameter potential Schrodinger equation bound states asymptotic iteration method

Adaptive Fault Detection Scheme Using an Optimized Self-healing Ensemble Machine Learning Algorithm

在线全文

学校读者我要写书评

暂无评论

CSEE Journal of Power and Energy Systems 2022年第4期8卷 1145-1156页

作者： Levent Yavuz ahmet Soran ahmetÖnen Xiangjun Li S.M.Muyeen Electrical and Computer Engineering Department in Abdullah Gül University Kayseri 38080Turkey Department of Electrical and Computer Engineering College of EngineeringSultan Qaboos UniversityAl-KhoudMuscat123Oman Department of Electrical Engineering Qatar UniversityDoha 2713Qatar State Key Laboratory of Control and Operation of Renewable Energy and Storage Systems China Electric Power Rescarch InstituteBeijing 100192China

This paper proposes a new cost-efficient,adaptive,and self-healing algorithm in real time that detects faults in a short period with high accuracy,even in the situations when it is difficult to *** than using traditional machine learning(ML)algorithms or hybrid signal processing techniques,a new framework based on an optimization enabled weighted ensemble method is developed that combines essential ML *** the proposed method,the system will select and compound appropriate ML algorithms based on Particle Swarm Optimization(PSO)*** this purpose,power system failures are simulated by using the PSCA D-Python *** of the salient features of this study is that the proposed solution works on real-time raw data without using any pre-computational techniques or pre-stored ***,the proposed technique will be able to work on different systems,topologies,or data *** proposed fault detection technique is validated by using PSCAD-Python co-simulation on a modified and standard IEEE-14 and standard IEEE-39 bus considering network faults which are difficult to detect.

关键词： Decision tree(DT) ensemble machine learning algorithm fault detection islanding operation k-Nearest Neighbor(kNN) linear discriminant analysis(LDA) logistic regression(LR) Naive Bayes(NB) self-healing algorithm

Comparative evaluation of different statistical tools for the prediction of uniaxial compressive strength of rocks

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Mining Science and Technology 2020年第6期30卷 785-797页

作者： ahmet Teymen Engin Cemal Mengüç Department of Mining Engineering Nigde Ömer Halisdemir University51240 NigdeTurkey Department of Electrical and Electronics Engineering Nigde Ömer Halisdemir University51240 NigdeTurkey

In this study,uniaxial compressive strength(UCS),unit weight(UW),Brazilian tensile strength(BTS),Schmidt hardness(SHH),Shore hardness(SSH),point load index(Is50)and P-wave velocity(Vp)properties were *** predict the UCS,simple regression(SRA),multiple regression(MRA),artificial neural network(ANN),adaptive neuro-fuzzy inference system(ANFIS)and genetic expression programming(GEP)have been *** obtained UCS values were compared with the actual UCS values with the help of various *** were modeled using different methods and compared with each *** the study where the performance indice PIat was used to determine the best performing method,MRA method is the most successful method with a small *** is concluded that the mean PIat equal to 2.46 for testing dataset suggests the superiority of the MRA,while these values are 2.44,2.33,and 2.22 for GEP,ANFIS,and ANN techniques,*** results pointed out that the MRA can be used for predicting UCS of rocks with higher capacity in comparison with *** to the performance index assessment,the weakest model among the nine model is P7,while the most successful models are P2,P9,and P8,respectively.

关键词： Uniaxial compressive strength Adaptive neuro-fuzzy inference system Multiple regression Artificial neural network Genetic expression programming