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Using nanotechnology to prevent fines migration while production

Petroleum 2021年第2期7卷 168-177页

作者： Mohamed Mansour Mohamed Eleraki ahmed Noah El-Abbas moustafa Faculty of Science Zagazig UniversityEgypt Egyptian Petroleum Research Institute(EPRI) Egypt The British University Egypt

Formation damage due to fines migration is a major reason for well productivity decline for oil and gas *** fines are small enough to pass through pore throats causing pore plugging and permeability *** factors affect fines migration such as flow rate,salinity,pH value,reservoir temperature and oil polarity,as well as changes in chemical environment induced by Enhanced Oil Recovery(EOR)*** paper focuses on the effect of flow rates on fines detachment from the grain surfaces,which causing permeability *** the fluid inside the reservoir moves towards the wellbore,the fluid velocity increases,when the fluid reaches the critical flow rate these fines can be picked up into the *** fines captured by thinner pore throats causing pore plugging and permeability *** concentrations of nanoparticles were used to fix these fines on their sources and prevent their mobilization at high flow *** unique technique used in this study is changing the potential surfaces between fines and grain surfaces to prevent fines movement above the critical flow ***_(2)and MgO NPs used in this study can be adsorbed on the pore surfaces and reduce the repulsion forces between fines and pore ***_(2) and MgO nanoparticles at different concentrations(0.25,0.50 and 0.75 g/L)were used on treating the Abu-Rawash sandstone reservoir using Formation Damage System Cell *** experimental studies showed that using MgO NPs would prevent fines detachment from the pore surfaces and decrease the reduction of permeability at high flow rates more than SiO_(2) *** optimum concentration of MgO NPs was at 0.5 g/L as the permeability remediation at this concentration reaches to 64.83%.

关键词： Formation damage Fines migration Nanoparticles Zeta potential Permeability reduction Fluid flow rate

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Validation of a serum microRNA panel as biomarkers for early diagnosis of hepatocellular carcinoma post-hepatitis C infection in Egyptian patients

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World Journal of Gastroenterology 2017年第21期23卷 3864-3875页

作者： moustafa Nouh Elemeery ahmed Noah Badr Marwa Anwar Mohamed Doaa ahmed Ghareeb Medical Biotechnology Laboratory Genetic Engineering and Biotechnology Research DivisionNational Research Centre Toxicology and Food Contaminant Laboratory Food Science and Nutrition Research DivisionNational Research Centre Department of Chemical Pathology Medical Research InstituteAlexandria University Molecular Biology Laboratory Faculty of ScienceAlexandria University

AIM To investigate the prospective importance of serum micro(mi)RNAs(mi R-125 b, mi R-138 b, mi R-1269, mi R-214-5p, mi R-494, mi R375 and mi R-145) as early biomarkers for the diagnosis of hepatitis C virus(HCV)-related hepatocellular carcinoma(HCC).METHODS Two-hundred and fifty HCV4 a patients, 224 HCV4 aHCC patients, and 84 healthy controls were enrolled in the study. Expression levels of mi R214-5p, mi R-125 b, mi R-1269 and mi R-375 were quantified using quantitative real-time *** Expression of the selected mi RNAs in serum wassignificantly lower in HCC patients than in the healthy controls, except for mi R-1269 and mi R-494. There was a significant difference between HCC and HCV patients, in particular for HCC and late stage fibrosis, rather than HCV patients and early fibrosis. It is obvious that mi R-1269 was significantly upregulated in HCC cases compared to hepatic fibrosis cases. Each mi RNA can show HCC progression. Multivariate logistic regression analysis indicated that the tested panel of mi RNAs(mi R214-5p, mi R-125 b, mi R-1269 and mi R-375) represent accurate and specific indictors of HCC *** This study presents a panel of mi RNAs with strong power as putative diagnostic and prognostic biomarkers for HCV-induced HCC. Moreover, mi R-214-5p and mi R-1269 could be considered as early biomarkers for tracking the progress of liver fibrosis to HCC.

关键词： Micro RNA Hepatocellular carcinoma Fibrosis progression

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Antifouling evaluation of extracts from Red Sea soft corals against primary biofilm and biofouling

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Asian Pacific Journal of Tropical Biomedicine 2017年第11期7卷 991-997页

作者： Yosry Abdel Aziz Soliman ahmed Mohammed Brahim ahmed Hussein moustafa Mohamed Abdel Fattah Hamed Marine Chemistry Lab. Marine Environment DivisionNational Institute of Oceanography and FisheriesSuezEgypt Department of Chemistry Faculty of ScienceZagazig UniversityZagazigEgypt

Objectives: To evaluate antifouling property of extracts from Red Sea soft corals against primary biofilm and ***: Seven species of soft corals Sarcophyton glaucum(a), Sinularia compressa,Sinularia cruciata(a), Heteroxenia fuscescens(a), Sarcophyton glaucum(b), Heteroxenia fuscescens(b) and Sinularia cruciata(b) were chosen to test their extracts as antibacterial and antifouling agents in Eastern Harbour of Alexandria, Mediterranean *** compounds of soft corals were extracted by using methanol and concentrated under vacuum. The residues of extracts were mixed in formulation of inert paint which consisted of rosin, chlorinated rubber and ferrous oxide against micro and macro fouling organisms. The formulated paints were then applied on PVC panels twice by brush,hanged in a steel frame and immersed in Eastern Harbour of Alexandria Mediterranean Sea followed by visual inspection and photographic ***: After 185 days of immersion in seawater, the antifouling results agreed with the antibacterial results where extracts of Sinularia compressa and Heteroxenia fuscescens(b) gave the best activity against marine fouling tubeworms and barnacles. The inhibition activity was correlated with the major functional groups(hydroxyl, amino, carbonyl,aliphatic(fatty acids), C]C of alkene or aromatic rings and CeC l of aryl halides) of the ***: The strong antifouling activity makes them promising candidates for new antifouling additives. After the screening and application of natural organic compounds from soft corals, marine organisms show activity against micro and macro fouling organisms.

关键词： Antibacterial Antifouling Paints Seawater Marine Organisms

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MicroRNA signature in patients with hepatocellular carcinoma associated with type 2 diabetes

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World Journal of Gastroenterology 2019年第42期25卷 6322-6341页

作者： moustafa Nouh Elemeery Marwa Anwar Mohamed Marwa ahmed Madkour Mohammed Mohammed Shamseya Noha Mahmoud Issa ahmed Noah Badr Doaa ahmed Ghareeb Cheol-Ho Pan Département de Neurosciences CRCHUMUniversitéde MontréalMontréalQuebec H2X 3E4Canada Medical Biotechnology Laboratory Genetic Engineering and Biotechnology Research DivisionNational Research CentreCairo 12622Egypt Natural Product Informatics Research Center KIST Gangneung Institute of Natural ProductsGangneung 25451South Korea Division of Bio-Medical Science and Technology KIST SchoolKorea University of Science and TechnologySeoul 02792South Korea Department of Chemical Pathology Medical Research InstituteAlexandria UniversityAlexandria 21511Egypt Experimental and Clinical Internal Medicine Department Medical Research InstituteAlexandria UniversityAlexandria 21511Egypt Human Genetics Department Medical Research InstituteAlexandria UniversityAlexandria 21511Egypt Food Toxicology and Contaminates Department National Research CentreDokkiCairo 12622Egypt Bioscreening and preclinical trial lab Biochemistry DepartmentFaculty of ScienceAlexandria UniversityAlexandria 12522Egypt Pharmaceutical and fermentation industries development center the city of scientific research and technological applicationsAlexandria 26411Egypt

BACKGROUND Nonalcoholic steatohepatitis-related cirrhosis is one of the liver complications in type 2 diabetes mellitus(T2DM)and reported to be a risk factor for developing hepatocellular carcinoma(HCC).A reliable screening biomarker of liver cirrhosis(LC)and HCC among T2DM patients is important to reduce the morbidity and mortality of this ***(miRNA)is considered a key player in HCC and T2DM,and it might be a hidden culprit in diabetes-associated HCC,making it a promising reliable prognostic *** To investigate the signature of serum miRNAs as early biomarkers for the screening of HCC among diabetic *** Expression profiles of miRNAs in serum samples of diabetic LC and diabetic HCC patients were assessed using Illumina sequencing;then,RT-qPCR was used to validate significantly altered miRNAs between the two *** miRNAs were tested in serum samples of 200 T2DM patients,270 LC patients,200 HCC patients,and 225 healthy control ***,receiver operating characteristic(ROC)analysis,with area under the curve(AUC),was performed to assess the diagnostic performance of the screened miRNAs for discriminating HCC from LC and nonmalignant patients(LC+T2DM).RESULTS Expression of the sequenced miRNAs in serum was different in HCC vs LCpositive T2DM *** miRNAs(miR-34a,miR-221)were significantly upregulated and five miRNAs(miR-16,miR-23-3p,miR-122-5p,miR-198,miR-199a-3p)were significantly down-regulated in HCC compared to LC *** of ROC curve demonstrated that the combination of these seven miRNAs can be used as a reliable biomarker for detection of HCC in diabetic patients,as it could identify HCC with high diagnostic accuracy in diabetic LC patients(AUC=0.993)and in diabetic nonmalignant patients(AUC=0.961).CONCLUSION This study validates a panel of serum miRNAs that can be used as a reliable noninvasive screening biomarker of HCC among T2DM cirrhotic and noncirrhotic *** study recommends furt

关键词： MicroRNA Hepatocellular carcinoma Type 2 diabetes Nonalcoholic fatty liver disease

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Antibacterial activity of various honey types of Algeria against Staphylococcus aureus and Streptococcus pyogenes

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Asian Pacific Journal of Tropical Medicine 2012年第10期5卷 773-776页

作者： ahmed moussa Djebli Noureddine Hammoudi Si Mohamed Meslem Abdelmelek Aissat Saad Institute of Veterinary Sciences University Ibn-khadoun Tiaret(14000) Algeria Departments of Biology Faculty of SciencesMostaganem UniversityAlgeria

Objective:To assess the in vitro antibacterial activity of honey from different geographical location on Gram negative ***:Different concentrations(Undiluted honey,10%, 30%,50%and 70%wt/vol) of honey were studied in vitro using Staphylococcus aureus(***) and Streptococcus pyogenes(***),briefly,two-fold dilutions of honey solutions were tested to determine the minimum inhibitory concentration(MIC) against each type of microorganism,followed by more assays within a narrower dilution range to obtain more precise MIC *** were determined by both visual inspection and spectrophotometric assay at 620 *** honey samples were compared with standard antibiotics like ampicillin,penicillin G,amoxicillin,gentamycin,tobramycin,erythromycin and chloramphenicol was determined by the disc diffusion ***:The diameter of zone of the inhibition(ZDI) of honey has various concentrations tested for the isolates ranged 0-46 mm for ***,0-44 mm for *** the MIC(%) ranged 12%-95%,25%-73%***:Algeria honey,in-vitro,possess antibacterial activity.

关键词： Honey Antibacterial activity Staphylococcus aureus Streptococcus pyogenes

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Numerical and experimental analyses of rock failure mechanisms due to microwave treatment

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Journal of Rock Mechanics and Geotechnical Engineering 2023年第10期15卷 2483-2495页

作者： Haitham M.ahmed Adel Ahmadihosseini Ferri Hassani Mohammed A.Hefni HussinA.M.ahmed Hussein A.Saleem Essam B.moustafa Agus P.Sasmito Mining Engineering Department King Abdulaziz UniversityJeddah21589Saudi Arabia Department of Mining and Materials Engineering McGill UniversityMontrealQCH3A0E8Canada Mechanical Engineering Department King Abdulaziz UniversityJeddah21589Saudi Arabia

Despite the extensive studies conducted on the effectiveness of microwave treatment as a novel rock preconditioning method,there is yet to find reliable data on the rock failure mechanisms due to microwave *** addition,there is no significant discussion on the energy efficiency of the method as one of the important factors among the mining and geotechnical engineers in the *** study presents a novel experimental method to evaluate two main rock failure mechanisms due to microwave treatment without applying any mechanical forces,*** and concentrated *** result shows that the existence of a small and concentrated fraction of a strong microwave absorbing mineral will change the failure mechanism from the distributed heating to the concentrated heating,which can increase the weakening over microwave efficiency(WOME)by more than 10 *** observation is further investigated using the developed coupled numerical *** is shown that at the same input energy,the existence of microwave absorbing minerals can cause major heat concentration inside the rock and increase the maximum temperature by up to three times.

关键词： Microwave treatment Numerical modeling Failure mechanism Energy efficiency Rock pre-conditioning

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Association of anxiety- depressive disorders with irritable bowel syndrome among patients attending a rural family practice center: a comparative cross- sectional study

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General Psychiatry 2021年第6期34卷 16-23页

作者： Alaa Adel Mohammed Heba ahmed moustafa Hebatallah Nour-Eldein Rabab Atta Saudi Family Medicine Department Suez Canal UniversityIsmailiaEgypt

Background Comorbidity of irritable bowel syndrome(IBS)and psychiatric disorders is common,and the prevalence of at least one psychiatric disorder has been reported as high as 80%among patients with *** To explore the association of anxiety-depressive disorders with IBS and its different subtypes,and to evaluate the associations of lifestyle habits,dietary habits and sleeping quality with *** A comparative cross-sectional study was conducted at the AL-Mahsama Family Practice Center,Ismailia,*** was carried out between October 2019 and October *** were categorised into 175 patients with IBS,diagnosed using the Rome IV criteria,and 175 patients without IBS.A semistructured questionnaire was used to collect data on sociodemographic characteristics,lifestyle habits,dietary habits and sleep quality from both *** Hamilton Anxiety Rating Scale was used to assess anxiety symptoms,whereas the Beck Depression Inventory Second Edition was used to assess depression *** There was a high statistically significant difference between both groups with regard to age,education,occupation and socioeconomic status(SES),being a smoker,being physically inactive,having sleep disturbance and having irregular meals;being either obese or overweight was more reported in the IBS *** was a high statistically significant difference in the rate of anxiety and depression between patients with and without ***,moderate and severe anxiety were reported in 37.1%,42.9%and 20.0%of patients with IBS while most(80.0%)of the patients without IBS reported mild *** depression,mild,moderate and severe depression were reported in 60.0%,14.3%and 25.7%of the patients with IBS while most(82.9%)of the non-IBS participants reported mild *** The study shows a significant association between anxiety-depressive disorders and IBS,but no significant associations between anxiety-depressive disorders and IBS subtypes.

关键词： patients disorders sectional

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Shadow Extraction and Elimination of Moving Vehicles for Tracking Vehicles

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Computers, Materials & Continua 2023年第11期77卷 2009-2030页

作者： Kalpesh Jadav Vishal Sorathiya Walid El-Shafai Torki Altameem moustafa HAly Vipul Vekariya Kawsar ahmed Francis MBui Department of Electronics&Communication Engineering Faculty of Engineering and TechnologyParul Institute of Engineering and TechnologyParul UniversityVadodaraGujarat391760India Department Electronics and Electrical Communications Engineering Faculty of Electronic EngineeringMenoufia UniversityMenouf32952Egypt Computer Science Department Community CollegeKing Saud UniversityRiyadh11362Saudi Arabia Electronics and Communications Engineering Department College of Engineering and TechnologyArab Academy for ScienceTechnology and Maritime TransportAlexandria1029Egypt Department of Computer Engineering Faculty of Engineering and TechnologyParul Institute of Engineering and TechnologyParul UniversityVadodaraGujarat391760India Department of Electrical and Computer Engineering University of Saskatchewan57 Campus DriveSaskatoonSK S7N5A9Canada

Shadow extraction and elimination is essential for intelligent transportation systems(ITS)in vehicle tracking *** shadow is the source of error for vehicle detection,which causes misclassification of vehicles and a high false alarm rate in the research of vehicle counting,vehicle detection,vehicle tracking,and *** of the existing research is on shadow extraction of moving vehicles in high intensity and on standard datasets,but the process of extracting shadows from moving vehicles in low light of real scenes is *** real scenes of vehicles dataset are generated by self on the Vadodara–Mumbai highway during periods of poor illumination for shadow extraction of moving vehicles to address the above *** paper offers a robust shadow extraction of moving vehicles and its elimination for vehicle *** method is distributed into two phases:In the first phase,we extract foreground regions using a mixture of Gaussian model,and then in the second phase,with the help of the Gamma correction,intensity ratio,negative transformation,and a combination of Gaussian filters,we locate and remove the shadow region from the foreground *** to the outcomes proposed method with outcomes of an existing method,the suggested method achieves an average true negative rate of above 90%,a shadow detection rate SDR(η%),and a shadow discrimination rate SDR(ξ%)of 80%.Hence,the suggested method is more appropriate for moving shadow detection in real scenes.

关键词： Change illuminations ImageJ software intelligent traffic systems mixture of Gaussian model National Institute of Health vehicle tracking

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Real-Time Multi-Class Infection Classification for Respiratory Diseases

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Computers, Materials & Continua 2022年第11期73卷 4157-4177页

作者： ahmed El.Shafee Walid El-Shafai Abdulaziz Alarifi Mohammed Amoon Aman Singh moustafa H.Aly Department of Electrical Engineering Faculty of EngineeringAhram Canadian UniversityGizaEgypt Department of Electronics and Electrical Communications Engineering Faculty of Electronic EngineeringMenoufia UniversityMenouf32952Egypt Department of Computer Science Community CollegeKing Saud UniversityRiyadh11437Saudi Arabia Higher Polytechnic School Universidad Europea del AtlánticoSantander39011Spain Electronics and Communications Engineering Department College of Engineering and TechnologyArab Academy for ScienceTechnology and Maritime TransportAlexandria1029Egypt

Real-time disease prediction has emerged as the main focus of study in the field of computerized *** disease identification framework can assist medical practitioners in diagnosing disease in a way that is reliable,consistent,and timely,successfully lowering mortality rates,particularly during endemics and *** prevent this pandemic’s rapid and widespread,it is vital to quickly identify,confine,and treat affected *** need for auxiliary computer-aided diagnostic(CAD)systems has *** recent studies have indicated that radiological pictures contained critical information regarding the COVID-19 *** advanced convolutional neural network(CNN)architectures in conjunction with radiological imaging makes it possible to provide rapid,accurate,and extremely useful susceptible *** research work proposes a methodology for real-time detection of COVID-19 infections caused by the Corona *** purpose of this study is to offer a two-way COVID-19(2WCD)diagnosis prediction deep learning system that is built on Transfer Learning Methodologies(TLM)and features customized fine-tuning on top of fully connected layered pre-trained CNN architectures.2WCD has applied modifications to pre-trained models for better *** is designed and implemented to improve the generalization ability of the classifier for binary and multi-class *** with the ability to differentiate COVID-19 and No-Patient in the binary class model and COVID-19,No-Patient,and Pneumonia in the multi-class model,our framework is augmented with a critical add-on for visually demonstrating infection in any tested radiological image by highlighting the affected region in the patient’s lung in a recognizable color *** proposed system is shown to be extremely robust and reliable for real-time COVID-19 diagnostic *** can also be used to forecast other lung-related *** the system can assist medical practitioner

关键词： COVID-19 real-time computerized disease prediction intelligent disease identification framework CAD systems X-rays CT-scans CNN real-time detection of COVID-19 infections

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Isolation, purification and structure elucidation of three newbioactive secondary metabolites from Streptomyces lividans AM

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BIOCELL 2021年第5期45卷 1263-1271页

作者： MOHAMMAD EL-METWALLY MAMDOUH ABDEL-MOGIB MANAL ELFEDAWY GAAD SOHSAH ahmed REZK MAHMOUD moustafa MOHAMED SHAABAN Botany and Microbiology Department Faculty of ScienceDamanhour UniversityDamanhour22511Egypt Chemistry Department Faculty of ScienceMansoura UniversityEl-Mansoura35516Egypt Bioprocess Development Department Genetic Engineering and Biotechnology Research InstituteCity of Scientific Research and Technological Applications(SRTA-City)New Borg El-Arab CityAlexandria21934Egypt Biology Department College of ScienceKing Khalid UniversityAbha9004Saudi Arabia Chemistry of Natural Compounds Department Division of Pharmaceutical IndustriesNational Research CentreDokki-Cairo12622Egypt Organic and Bioorganic Chemistry Department of ChemistryBielefeld UniversityBielefeld33615Germany

Microorganisms are a huge mine of bioactive metabolites,and actinomycetes are one of the very active groups in this *** this article,we are concerned about the full taxonomical characterization of Streptomyces lividans AM,isolated from Egyptian *** isolate produced three new bioactive metabolites,namely:1-Nona-decanoyl,4-oleyl disuccinate(1),filoboletic acid;(9Z,11E)-8,13-dihydroxy octadeca-9,11-dienoic acid(2),and sitosteryl-3β-D-glucoside(3).Extensive 1D and 2D NMR and HR-mass spectrometry were used to elucidate the structures of the three ***,ten known compounds were also *** antimicrobial activity of the producing organism and newly reported compounds(1–3)was investigated against a selected group of pathogenic microorganisms.A full taxonomical characterization of the strain was described as well.

关键词： Bioactive metabolites Streptomyces sp. Taxonomy Biological activity

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