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Prognostic significance of peritoneal metastasis from colorectal cancer treated with first-line triplet chemotherapy

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World Journal of Clinical Cases 2022年第8期10卷 2429-2438页

作者： Shouki Bazarbashi Abdulrahman Alghabban mohamed Aseafan ali H Aljubran ahmed Alzahrani Tusneem AM Elhassan Oncology Center King Faisal Specialist Hospital&Research CenterRiyadh 11211RiyadhSaudi Arabia

BACKGROUND Peritoneal metastasis from colorectal cancer(CRC)carries a poor prognosis in most *** majority of those studies used either a single-agent or doublet chemotherapy regimen in the first-line *** To investigate the prognostic significance of peritoneal metastasis in a cohort of patients treated with triplet chemotherapy in the first-line *** We retrospectively evaluated progression-free survival(PFS)and overall survival(OS)in 51 patients with metastatic CRC treated in a prospective clinical trial with capecitabine,oxaliplatin,irinotecan,and bevacizumab in the first-line setting according to the presence and absence of peritoneal ***,univariate and multivariate analyses for PFS and OS were performed to assess the prognostic significance of peritoneal metastasis at the multivariate *** Fifty-one patients were treated with the above triplet *** had peritoneal *** patient characteristics of both groups showed a significant difference in the sidedness of the primary tumor(left-sided primary tumor in 60%of the peritoneal group vs 86%in the nonperitoneal group,P=0.03)and the presence of liver metastasis(40%for the peritoneal group vs 75%for the nonperitoneal group,P=0.01).Univariate analysis for PFS showed a statistically significant difference for age less than 65 years(P=0.034),presence of liver metastasis(P=0.046),lung metastasis(P=0.011),and those who underwent metastasectomy(P=0.001).Only liver metastasis and metastasectomy were statistically significant for OS,with P values of 0.001 and 0.002,*** analysis showed that age(less than 65 years)and metastasectomy were statistically significant for PFS,with P values of 0.002 and 0.001,*** the other hand,the absence of liver metastasis and metastasectomy were statistically significant for OS,with P values of 0.003 and 0.005,*** Peritoneal metastasis in patients with metastatic CRC tre

关键词： Colorectal cancer Peritoneal carcinomatosis Triplet chemotherapy Survival Prognostic factors Metastasectomy

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Using nanotechnology to prevent fines migration while production

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Petroleum 2021年第2期7卷 168-177页

作者： mohamed Mansour mohamed Eleraki ahmed Noah El-Abbas Moustafa Faculty of Science Zagazig UniversityEgypt Egyptian Petroleum Research Institute(EPRI) Egypt The British University Egypt

Formation damage due to fines migration is a major reason for well productivity decline for oil and gas *** fines are small enough to pass through pore throats causing pore plugging and permeability *** factors affect fines migration such as flow rate,salinity,pH value,reservoir temperature and oil polarity,as well as changes in chemical environment induced by Enhanced Oil Recovery(EOR)*** paper focuses on the effect of flow rates on fines detachment from the grain surfaces,which causing permeability *** the fluid inside the reservoir moves towards the wellbore,the fluid velocity increases,when the fluid reaches the critical flow rate these fines can be picked up into the *** fines captured by thinner pore throats causing pore plugging and permeability *** concentrations of nanoparticles were used to fix these fines on their sources and prevent their mobilization at high flow *** unique technique used in this study is changing the potential surfaces between fines and grain surfaces to prevent fines movement above the critical flow ***_(2)and MgO NPs used in this study can be adsorbed on the pore surfaces and reduce the repulsion forces between fines and pore ***_(2) and MgO nanoparticles at different concentrations(0.25,0.50 and 0.75 g/L)were used on treating the Abu-Rawash sandstone reservoir using Formation Damage System Cell *** experimental studies showed that using MgO NPs would prevent fines detachment from the pore surfaces and decrease the reduction of permeability at high flow rates more than SiO_(2) *** optimum concentration of MgO NPs was at 0.5 g/L as the permeability remediation at this concentration reaches to 64.83%.

关键词： Formation damage Fines migration Nanoparticles Zeta potential Permeability reduction Fluid flow rate

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Obstructive sleep apnea syndrome and fatty liver: Association or causal link?

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World Journal of Gastroenterology 2010年第34期16卷 4243-4252页

作者： mohamed H ahmed Christopher D Byrne Chemical Pathology Department Southampton University Hospital NHS Trust Southampton SO16 6YD United Kingdom Endocrinology and Metabolism DOHaD Division University of Southampton and Southampton University Hospitals Trust Southampton SO16 6YD United Kingdom

Obstructive sleep apnea (OSA) is a complex disorder that consists of upper airway obstruction, chronic intermittent hypoxia and sleep fragmentation. OSA is well known to be associated with hypoxia, insulin resistance and glucose intolerance, and these factors can occur in the presence or absence of obesity and metabolic syndrome. Although it is well established that insulin resistance, glucose intolerance and obesity occur frequently with non-alcoholic fatty liver disease (NAFLD), it is now becoming apparent that hypoxia might also be important in the development of NAFLD, and it is recognized that there is increased risk of NAFLD with OSA. This review discusses the association between OSA, NAFLD and cardiovascular disease, and describes the potential role of hypoxia in the development of NAFLD with OSA.

关键词： Sleep apnea syndrome Hyperlipidemia Non-alcoholic fatty liver disease Insulin resistance

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Contralateral eye study of refractive,topographic and aberrometric outcomes after femtosecond assisted Myo Ring implantation and DALK for management of keratoconus

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International Journal of Ophthalmology(English edition) 2018年第10期11卷 1621-1630页

作者： mohamed Omar Yousif Azza mohamed ahmed Said Department of Ophthalmology Faculty of Medicine Ain Shams University

AIM：To evaluate the efficacy of femtosecond laser assisted MyoRing intrastromal corneal implant and deep anterior lamellar keratoplasty （DALK） for management of moderate to advanced keratoconus regarding the degree of changes in visual acuity, refraction, corneal asphericity and ***：A prospective non comparative interventional case study was conducted in Ophthalmology Department,Ain Shams University Hospital in the period from January 2015 to February 2017. The study included 30 eyes of moderate to advanced keratoconus. MyoRing was implanted in one eye （Group Ⅰ） and DALK operation was performed in the contralateral eye of the same patient （Group Ⅱ）.Preoperative and 6mo post-operative uncorrected visual acuity（UCVA）, corrected distance visual acuity （CDVA）, spherical equivalent （SE）, corneal and refractive astigmatisms,keratometry and Q-value using topography images were acquired. Quality of vision was assessed in all eyes including total corneal, anterior corneal high order aberrations analysis at 5 mm pupil size and the Strehl ratio of point spread function （PSF） as an objective measure of ***：Mean postoperative UCVA, CDVA, SE, refractive astigmatism,keratometryreadingsandasphericity were statistically improved compared to preoperative parameters in both groups （P〈0.05）. Significant reduction of all corneal aberrations following both techniques（P〈0.05） was achieved except mean trefoil and mean PSF in Group Ⅰ （P〉0.05）. Postoperative corneal aberrations were significantly lower in Group Ⅱ compared to Group Ⅰ.A statistically significant negative correlation was found in Group Ⅰ between the mean change in CDVA （logMAR）and the mean preoperative and mean postoperative total corneal aberrations root mean square （RMS; r=-0.78,P=0.04）. Also a statistically significant negative correlation was found between mean preoperative coma RMS and mean post PSF （r=-0.86, P=0.01）. In Group Ⅱ, there was a statistically significant positive correlation between m

关键词： aberrations deep anterior lamellar keratoplasty femtosecond laser keratoconus MyoRing

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Finding an optimization of the plate element of Egyptian research reactor using genetic algorithm

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Nuclear Science and Techniques 2008年第5期19卷 314-320页

作者： WAHED mohamed IBRAHIM Wesam EFFAT ahmed Mathematics Department Faculty of ScienceZagazic UniversityEgypt Atomic Energy Authority CairoEgypt

The second Egyptian research reactor ET-RR-2 went critical on the 27th of November *** National Center of Nuclear Safety and Radiation Control (NCNSRC) has the responsibility of the evaluation and assessment of the safety of this *** purpose of this paper is to present an approach to optimization of the fuel element plate. For an efficient search through the solution space we use a multi objective genetic algorithm which allows us to identify a set of Pareto optimal solutions providing the decision maker with the complete spectrum of optimal solutions with respect to the various *** aim of this paper is to propose a new approach for optimizing the fuel element plate in the *** fuel element plate is designed with a view to improve reliability and lifetime and it is one of the most important elements during the shut *** this present paper,we present a conceptual design approach for fuel element plate,in conjunction with a genetic algorithm to obtain a fuel plate that maximizes a fitness value to optimize the safety design of the fuel plate.

关键词：埃及核反应堆遗传算法燃料元件核技术

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Improving low-voltage ride-through capability of a multimegawatt DFIG based wind turbine under grid faults

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Protection and Control of Modern Power Systems 2020年第1期5卷 390-402页

作者： mohamed Nadour ahmed Essadki Tamou Nasser Research Center of Engineering and Health Science and Technologies(STIS) High Normal School of Technical Education(ENSET)Mohammed V UniversityRabatMorocco Research Center of Engineering and Health Science and Technologies Higher National School of Computer Science and Systems Analysis(ENSIAS)Mohammed V UniversityRabatMorocco

Large integration of doubly-fed induction generator(DFIG)based wind turbines(WTs)into power networks can have significant consequences for power system operation and the quality of the energy supplied due to their excessive sensitivity towards grid *** voltage dips,the resulting overcurrent and overvoltage in the rotor circuit and the DC link of a DFIG,could lead to the activation of the protection system and WT *** potentially results in sudden loss of several tens/hundreds of MWs of energy,and consequently intensifying the severity of the *** paper aims to combine the use of a crowbar protection circuit and a robust backstepping control strategy that takes into consideration of the dynamics of the magnetic flux,to improve DFIG’s Low-Voltage Ride Through capability and fulfill the latest grid code *** the power electronic interfaces are protected,the WTs also provide large reactive power during the fault to assist system voltage *** results using Matlab/Simulink demonstrate the effectiveness of the proposed strategy in terms of dynamic response and robustness against parametric variations.

关键词： Wind turbine DFIG Grid faults Crowbar protection Backstepping control Low-voltage ride through

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Investigating energy policies to boost grid-connected rooftop solar PV in Sudan

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Clean Energy 2023年第5期7卷 994-1005页

作者： Tarig Z.ahmed Ayah mohamed Mawahib Eltayeb ahmed ahmed Osman Elamin Abdalgader mohamed G.Hassan-Sayed Cambridge Institute for Sustainability Leadership(CISL) University of CambridgeCambridgeCB21QAUK Energy and Climate Change Division Faculty of Engineering and Physical ScienceThe University of SouthamptonSouthamptonSO171BJUK Institute of Engineering Research and Material Technology National Centre for ResearchKhartoumSudan/University of KhartoumSudan University of California Davis1 Shields AveDavisCA 95616USA School of Chemistry Faculty of Engineering and Physical SciencesThe University of SouthamptonSouthamptonSO171BJUK

Grid-connected rooftop solar photovoltaic(PV)systems can reduce the energy demand from the grid and significantly increase the power available to ***,rooftop solar PV has not yet been widely adopted in many sub-Saharan African countries,such as Sudan,although they are endowed with high solar radiation and in dire need of additional *** paper investigates risks and policies to increase grid-connected rooftop solar PV adoption in Sudan.A simplified United Nations Development Program Derisking Renewable Energy Investment framework is adopted to investigate this over three *** Stage 1,a list of risks and barriers was produced based on a literature review of solar PV studies in Sudan and interviews with nine *** was the risk most often mentioned(eight times from nine interviewees),followed by concerns about poor utility grid *** Stage 2,policy de-risking instruments and financial de-risking instruments were listed to overcome the *** include the intro-duction of net metering,the use of a third-party organization to monitor policy implementation,upgrade of the grid infrastructure,public awareness campaigns and energy-saving *** Stage 3,the levelized cost of electricity was estimated for a typical 2-kW rooftop PV system without policies(0.11$/kWh)and with a net-metering policy(0.07$/kWh).

关键词： energy policy rooftop solar PV Sudan energy poverty sustainable development photovoltaics

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Composite Solid Rocket Propellant Based on GAP Polyurethane Matrix with Different Binder Contents

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火炸药学报 2020年第4期43卷 362-367页

作者： Islam KBoshra ahmed Elbeih GUO Lin mohamed GZaki School of Chemistry and Environment Beihang UniversityBeijing 100191China Military Technical College Kobry ElkobbahCairoEgypt

Different GAP-based CSRP samples with different binder contents were prepared and compared with that of conventional HTPB *** crosslinker mixture of trimethylol propane(TMP)and butane diol(BD)was used in the GAP matrix beside the addition of dibutyltin dilaurate(DBTDL)to ensure cross-linking and curing completion of the prepared *** viscosity and hardness of all prepared formulations were monitored continuously during the curing *** mechanical characteristics of cured samples were *** burning rate at operating pressure and specific impulse were measured,while the theoretical specific impulse(I sp)was calculated by ICT code and compared with the measured *** to the results,DOA was found to be a suitable plasticizer for GAP when using in *** mechanical properties of CSRP with 25%GAP can produce the optimum mechanical behavior,which is close to that of HTPB-based *** optimum GAP-based formulation is one candidate to replace the traditional HTPB-based CSRP with high burning rate for some applications.

关键词： physical chemistry glycidyl azide polymer(GAP) hydroxyl terminated polybutadiene(HTPB) cross-linker mechanical properties

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Standard precaution measurements during ophthalmology practice in the pandemic stage of COVID-19

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International Journal of Ophthalmology(English edition) 2020年第7期13卷 1017-1022页

作者： ahmed mohamed Reda Wael M.ahmed Department of ophthalmology Faculty of MedicineAin Sham UniversityCairo 11566Egypt Dar Eloyoun Eye Laser Centers Muscat 118Oman

AIM:To take specific precautions and keep a safe practice during providing ophthalmology health services without compromising the patient’s safety as well as the team workers and the community in the pandemic stage of corona virus disease 2019(COVID-19).METHODS:Applying patient circulation scheme implemented in our ophthalmology centers with the guidance of ministry of health infection control guidelines star ted from the moment that we receive a call or Whats App message or Facebook inquiry from patients until 21 d after patients first visit if *** directions were ***,community awareness of the disease and the ophthalmology related advices in how eye can transfers the infection and how to protect our eyes not to be infected through videos interviews of our consultants and distribution in social media like Instagram,Facebook,Whats App pages radio and TV interviews as well as leaflet health awareness for distribution for ***,scheduling of patients’appointments to prevent overcrowdings and cross ***,protective measurements tools in the center to detect and prevent any exposure of the patients to patients and to protect medical staff,COVID-19 scoring system was set up to identify patients with fever,respiratory symptoms,acute conjunctivitis or recent travel to outbreak areas and to encourage these individuals to postpone their appointments for at least 21 *** use of personal protective equipment was *** all the elective surgeries keeping only the emergency types advised by fourth:how to deal with our patients if they need an urgent ophthalmological intervention and how to deal with suspected cases of corona if any cases ***:Our measures helped our colleagues to try to keep providing ophthalmology health services without increasing the incidence of infection for COVID-19 until this pandemic is ***:In our practice,ophthalmologists should work with new aura of social media to facilitate the

关键词： corona virus COVID-19 Instagram Facebook WhatsApp personal protective equipment

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Nickel-titanium shape memory alloys made by selective laser melting:a review on process optimisation

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Advances in Manufacturing 2022年第1期10卷 24-58页

作者： Omar ahmed mohamed Syed Hasan Masood Wei Xu School of Engineering Deakin UniversityGeelongVIC 3216Australia Department of Mechanical Engineering The Higher Institute of Engineering TechnologyBani WaledLibya Department of Mechanical and Product Design Engineering Swinburne University of TechnologyHawthornVIC 3122Australia

Selective laser melting(SLM)is a mainstream powder-bed fusion additive manufacturing(AM)process that creates a three-dimensional(3D)object using a high power laser to fuse fine particles of various metallic powders such as copper,tool steel,cobalt chrome,titanium,tungsten,aluminium and stainless *** the past decade,SLM has received significant attention due to its capability in producing dense parts with superior mechanical *** a premier shape memory alloy,the nickel-titanium(NiTi)shape memory alloy is attractive for a variety of biomedical applications due to its superior mechanical properties,superelasticity,corrosion resistance and *** paper presents a comprehensive review of the recent progress in NiTi alloys produced by the SLM process,with a particular focus on the relationship between processing parameters,resultant microstructures and *** research gaps,challenges and suggestions for future research are also addressed.

关键词： Additive manufacturing(AM) Selective laser melting(SLM) Microstructure NiTi alloy Mechanical properties

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