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Seroprevalence of brucellosis among exposed agro-pastoral communities in southern Saudi Arabia

Asian Pacific Journal of Tropical medicine 2019年第12期12卷 545-551页

作者： ahmed m.al-hakami Abdulah J.alqahtani Riyad A.moosa Sultan K.Kadasah Talal Y.Gofashe Amer F.Binzafrah Abdulrahman m.almobty Ihab Abdulrahim Abdullah m.alkahtani Shehata F.Shehata mohamed E.Hamid Department of microbiology and Clinical Parasitology College of MedicineKing Khalid UniversityAbhaSaudi Arabia Level 12 mBBS Students College of MedicineKing Khalid UniversityAbhaSaudi Arabia Family and Community medicine College of MedicineKing Khalid UniversityAbhaSaudi Arabia Department of Biostatistics High Institute of Public healthAlexandria UniversityEgypt Center of Tropical Diseases College of MedicineKing Khalid UniversityAbhaSaudi Arabia

Objective: To investigate the prevalence and risk factors of brucellosis in human and animal’s communities in southern Saudi ***: A cross-sectional sero-epidemiological study was conducted in Aseer and Jazan, Saudi Arabia(October 2017-October 2018). Human serum samples(n=339) were initially screened for Brucella antibodies and positive samples were further titrated for Brucella antibodies by immunocapture assay(titer of ≥1:320 as positive). Animal samples(n=828) were screened using the Rose Bengal test. Relationship status was dichotomized to measure and predict independent contributions to variations in human using univariate and multivariate stepwise binary logistic regression model. Results: The rate of brucellosis among the 339 human samples in the two regions was 33.9%, and the rate of acute brucellosis was 12.4%. The rate of brucellosis in animals was 4.7%. Human brucellosis among the target groups was higher in northwestern Aseer(53.3%) compared to Southeastern Aseer(25.9%) and Jazan region(20.6%). The disease was more prevalent among non-Saudi nationals(35.2%) compared to Saudis(30.5%). The rate of brucellosis among butchers and shepherds was 37.5% and 37.2%, respectively. The rate of brucellosis was 37.8% in people over 30 years of age. Our univariate analysis showed that residing in Aseer region(OR: 2.60, 95% CI: 1.50-4.40), especially residing in northwestern Aseer region(OR: 4.40, 95% CI: 2.40-7.90), frequent consumption of raw meat(OR: 2.90, 95% CI: 1.50-5.50), shepherds(OR: 2.10, 95% CI: 0.80-5.30), owning sheep(OR: 2.20, 95% CI: 1.10-4.40), daily contact with animals(OR: 2.10, 95% CI: 0.75-5.80), and those > 30-year-old(OR: 1.50, 95% CI: 1.00-2.40) were significantly associated with increased risks of brucellosis. Our multivariate analysis further showed that residing in northwestern Aseer(OR: 9.16, 95% CI: 3.39-24.76) and having sheep(OR: 1.16, 95% CI: 1.00-1.35) were significant and independent risks of brucellosis while residing in agric

关键词： Undulant fever Zoonosis Serological assays Brucellosis Aseer

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Efficient ECG classification based on Chi-square distance for arrhythmia detection

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Journal of Electronic Science and Technology 2024年第2期22卷 1-15页

作者： Dhiah al-Shammary mustafa Noaman Kadhim ahmed m.mahdi Ayman Ibaida Khandakar ahmedb College of Computer Science and Information Technology University of Al-QadisiyahAl Diwaniyah58001Iraq Intelligent Technology Innovation Lab Victoria UniversityMelbourne3011Australia

This study introduces a new classifier tailored to address the limitations inherent in conventional classifiers such as K-nearest neighbor(KNN),random forest(RF),decision tree(DT),and support vector machine(SVm)for arrhythmia *** proposed classifier leverages the Chi-square distance as a primary metric,providing a specialized and original approach for precise arrhythmia *** optimize feature selection and refine the classifier’s performance,particle swarm optimization(PSO)is integrated with the Chi-square distance as a fitness *** synergistic integration enhances the classifier’s capabilities,resulting in a substantial improvement in accuracy for arrhythmia *** results demonstrate the efficacy of the proposed method,achieving a noteworthy accuracy rate of 98% with PSO,higher than 89% achieved without any previous *** classifier outperforms machine learning(mL)and deep learning(DL)techniques,underscoring its reliability and superiority in the realm of arrhythmia *** promising results render it an effective method to support both academic and medical communities,offering an advanced and precise solution for arrhythmia detection in electrocardiogram(ECG)data.

关键词： Arrhythmia classification Chi-square distance Electrocardiogram(ECG)signal Particle swarm optimization(PSO)

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Appropriate Combination of Crossover Operator and mutation Operator in Genetic algorithms for the Travelling Salesman Problem

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Computers, materials & Continua 2024年第5期79卷 2399-2425页

作者： Zakir Hussain ahmed Habibollah Haron Abdullah al-Tameem Department of mathematics and Statistics College of ScienceImam Mohammad Ibn Saud Islamic University(IMSIU)Riyadh11432Kingdom of Saudi Arabia Faculty of Computing Universiti Teknologi MalaysiaJohor Bahru81310Malaysia College of Computer and Information Sciences Imam Mohammad Ibn Saud Islamic University(IMSIU)Riyadh11432Kingdom of Saudi Arabia

Genetic algorithms(GAs)are very good metaheuristic algorithms that are suitable for solving NP-hard combinatorial optimization *** a set of solutions represented by a population of chromosomes and then uses the idea of survival of the fittest in the selection process to select some fitter *** uses a crossover operator to create better offspring chromosomes and thus,converges the ***,it uses a mutation operator to explore the unexplored areas by the crossover operator,and thus,diversifies the GA search space.A combination of crossover and mutation operators makes the GA search strong enough to reach the optimal ***,appropriate selection and combination of crossover operator and mutation operator can lead to a very good GA for solving an optimization *** this present paper,we aim to study the benchmark traveling salesman problem(TSP).We developed several genetic algorithms using seven crossover operators and six mutation operators for the TSP and then compared them to some benchmark TSPLIB *** experimental studies show the effectiveness of the combination of a comprehensive sequential constructive crossover operator and insertion mutation operator for the *** GA using the comprehensive sequential constructive crossover with insertion mutation could find average solutions whose average percentage of excesses from the best-known solutions are between 0.22 and 14.94 for our experimented problem instances.

关键词： Travelling salesman problem genetic algorithms crossover operator mutation operator comprehensive sequential constructive crossover insertion mutation

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macrophage modulation with dipeptidyl peptidase-4 inhibitors:A new frontier for treating diabetic cardiomyopathy?

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World Journal of Diabetes 2024年第9期15卷 1847-1852页

作者： Saeed mohammadi ahmed al-Harrasi Natural and medical Sciences Research Center University of NizwaNizwa 616Oman Department of Biological Sciences and Chemistry University of NizwaNizwa 616Oman

This editorial introduces the potential of targeting macrophage function for diabetic cardiomyopathy(DCm)treatment by dipeptidyl peptidase-4(DPP-4)*** et al studied teneligliptin,a DPP-4 inhibitor used for diabetes management,and its potential cardioprotective effects in a diabetic mouse *** suggested teneligliptin administration may reverse established markers of DCm,including cardiac hypertrophy and compromised *** also inhibited the NLRP3 inflammasome and reduced inflammatory cytokine production in diabetic *** play crucial roles in DCm *** hyperglycemia disturbs the balance between pro-inflammatory(m1)and antiinflammatory(m2)macrophages,favoring a pro-inflammatory state contributing to heart ***,we highlight the potential of DPP-4 inhibitors to modulate macrophage function and promote an anti-inflammatory *** compounds may achieve this by elevating glucagon-like peptide-1 levels and potentially inhibiting the NLRP3 *** studies on teneligliptin in combination with other therapies targeting different aspects of DCm could be suggested for developing more effective treatment strategies to improve cardiovascular health in diabetic patients.

关键词： Diabetic cardiomyopathy macrophage Dipeptidyl peptidase-4 inhibitor Teneligliptin NLRP3 inflammasome Glucagon-like peptide-1

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A Novel Layered Double Hydroxide and Dodecyl alcohol Assisted PCm Composite with High Latent Heat Storage Capacity and Thermal Conductivity

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Journal of Thermal Science 2024年第2期33卷 537-547页

作者： al-ahmed Amir SARI Ahmet KHAN Firoz al-RASHEIDI masoud Hekimoğlu Gökhan AFZAal mohammad A.alSULAmI ahmed DAFalLA Hatim SalHI Billel A.alSULAImAN Fahad Interdisciplinary Research Center for Renewable Energy and Power Systems(IRC-REPS) King Fahd University of Petroleum&MineralsDhahran31261Saudi Arabia Department of metallurgical and material Engineering Karadeniz Technical UniversityTrabzon61080Turkey maths and Natural Sciences Division Higher Colleges of TechnologyP.O.Box 7947SharjahUnited Arab Emirates Department of mechanical Engineering King Fahd University of Petroleum&MineralsDhahran31261Saudi Arabia Core Research Facilities King Fahd University of Petroleum&MineralsDhahran31261Saudi Arabia Interdisciplinary Research Center for membranes and Water Security King Fahd University of Petroleum&MineralsDhahran31261Saudi Arabia

Dodecyl alcohol(DDA) is a promising solid-liquid phase change material(PCm) due to its favorable latent heat storage(LHS) ***,the leakage issue of PCm in a melted state during the heating period and low thermal conductivity restricts its utilization potential in thermal energy storage(TES) *** the same context,the present work aims to overcome the leakage issue and improve the thermal conductivity of the *** this in mind,a novel leak-proof layered double hydroxide(LDH)/DDA composite PCm is proposed through a solution-based impregnation *** leak-proof impregnation ratio of the DDA impregnated within the cavities of the synthesized al/Fe-LDH was determined to be 60%.Detailed morphological,physicochemical,and thermal properties of the fabricated composite were studied by scanning electron microscopy(SEm),Fourier transforms infrared(FTIR) spectroscopy,X-ray diffraction(XRD)spectroscopy,differential scanning calorimetry(DSC),thermalgravimetric analysis(TGA),and thermal cycling *** results show that the LDH/DDA composite has a suitable phase change temperature(about 20℃) for passive solar thermal management of building *** composite PCm showed high LHS enthalpy(about136 J/g),good thermal stability,and cycling LHS *** also showed nearly 152% higher thermal conductivity compared to that of pure DDA,ultimately reducing the melting and solidification time of the pure DDA by 44.9% and 45.5%,respectively.

关键词： dodecyl alcohol layered double hydroxide composite PCm thermal conductivity thermal energy storage(TES)

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Interplay of serum biomarkers bilirubin andγ-glutamyltranspeptidase in predicting cardiovascular complications in type-2 diabetes mellitus

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World Journal of Diabetes 2024年第6期15卷 1074-1078页

作者： Ebtesam Abdullah al-Suhaimi Abdullah ahmed al-Rubaish Scientific Research and Innovation Imam Abdulrahman Bin Faisal UniversityDammam 31441Saudi Arabia King Abdulaziz and his Companions Foundation for Giftedness and Creativity“mawhiba” Riyadh 11372Saudi Arabia College of medicine Imam Abdulrahman Bin Faisal UniversityDammam 31441Saudi Arabia

This editorial synthesizes insights from a series of studies examining the interplay between metabolic and oxidative stress biomarkers in cardiovascular disease(CVD),focusing particularly on type-2 diabetes mellitus(T2Dm)and acute coronary syndrome(ACS).The central piece of this synthesis is a study that investigates the balance between oxidative stress and antioxidant systems in the body through the analysis of serum bilirubin andγ-glutamyltranspeptidase(γ-GGT)levels in T2Dm patients with *** study highlights serum bilirubin as a protective antioxidant factor,while elevatedγ-GGT levels indicate increased oxidative stress and correlate with major adverse cardiovascular *** to this,other research contributions revealγ-GGT’s role as a risk factor in ACS,its association with cardiovascular mortality in broader populations,and its link to metabolic syndrome,further elucidating the metabolic dysregulation in *** collective findings from these studies underscore the critical roles ofγ-GGT and serum bilirubin in cardiovascular health,especially in the context of T2Dm and *** providing a balanced view of the body’s oxidative and antioxidative mechanisms,these insights suggest potential pathways for targeted interventions and improved prognostic assessments in patients with T2Dm and *** synthesis not only corroborates the pivotal role ofγ-GGT in cardiovascular pathology but also introduces the protective potential of antioxidants like bilirubin,illuminating the complex interplay between T2Dm and heart *** studies collectively underscore the critical roles of serum bilirubin andγ-GGT as biomarkers in cardiovascular health,particularly in T2Dm and ACS contexts,offering insights into the body’s oxidative and antioxidative *** synthesis of research supports the potential of these biomarkers in guiding therapeutic strategies and improving prognostic assessments for patients with T2Dm and some CVD.

关键词： Type-2 diabetes mellitus Acute coronary syndrome Serum biomarkers γ-glutamyltranspeptidase Bilirubin Cardiovascular disease

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Quantitative and Qualitative Responses of Hydroponic Tomato Production to Different Levels of Salinity

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Phyton-International Journal of Experimental Botany 2024年第6期93卷 1311-1323页

作者： Khalid A.al-Gaadi ahmed m.Zeyada ElKamil Tola Abdullah m.alhamdan Khalid A.m.ahmed Rangaswamy madugundu mohamed K.Edrris Department of Agricultural Engineering College of Food and Agriculture SciencesKing Saud UniversityRiyadh11451Saudi Arabia Precision Agriculture Research Chair Deanship of Scientific ResearchKing Saud UniversityRiyadh11451Saudi Arabia Chair of Dates Industry&Technology Deanship of Scientific ResearchKing Saud UniversityRiyadh11451Saudi Arabia Agricultural Research Centre Agricultural Engineering Research Institute(AEnRI)Giza12619Egypt

From economic and nutritional points of view,tomato is,historically,considered one of the most important *** signiﬁcant yield reduction,most commercial cultivars of tomato crops are sensitive to moderate levels of ***,high levels of salt stress can negatively affect the yield and quality of tomato ***,this study was conducted to evaluate the yield and fruit quality of three tomato cultivars(Forester,Ghandowra-F1,and Feisty-Red)cultivated hydroponically,under three different levels of nutrient solution *** of tomato fruits was performed based on quantity(number and weight of fruits,and total fruit yield),physical quality(color andﬁrmness),and chemical quality(refractometric index“Brix”,pH,EC,K^(+),Na^(+),and NO_(3)-).Experiments were conducted using three salinity levels of the nutrient solution with electrical conductivity values(dSm^(-1))of 2.5(control),6.0,and *** showed that the studied tomato cultivars were signiﬁcantly inﬂuenced by high salinity(9.5 dSm^(-1))in comparison to the low(2.5 dSm^(-1))and medium(6.0 dSm^(-1))levels of *** average,the highest fruit weight per plant of 1944.84 g and total fruit yield of 4.42 kgm^(-2) were observed at the low salinity level;however,no signiﬁcant differences were obtained in the two yield factors(single fruit weight and total fruit yield)for the low and medium salinity *** the other hand,a signiﬁcant reduction in tomato yield(31%)was associated with the high salinity level compared to the yield at low and medium salinity *** of physical quality parameters showed highly signiﬁcant differences among all salinity *** average,the maximum value of color change(1.72)was associated with the medium salinity level,and the maximum value ofﬁrmness(9.61 Ncm^(-1))was recorded at the high salinity *** levels and tomato cultivars introduced signiﬁcant differences in chemical quality parameters;however,no signiﬁcant differences in these

关键词： Quality cultivars yield color ﬁrmness brix

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A Hybrid Classification and Identification of Pneumonia Using African Buffalo Optimization and CNN from Chest X-Ray Images

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Computer modeling in Engineering & Sciences 2024年第3期138卷 2497-2517页

作者： Nasser alalwan ahmed I.Taloba Amr Abozeid ahmed Ibrahim.alzahrani ali H.al-Bayatti Computer Science Department Community CollegeKing Saud UniversityRiyadh11437Saudi Arabia Information System Department Faculty of Computers and InformationAssiut UniversityAssiutEgypt mathematics Department Faculty of ScienceAl-Azhar UniversityCairoEgypt Cyber Technology Institute(CTI) De Montfort UniversityLeicesterUK

An illness known as pneumonia causes inflammation in the *** there is so much information available fromvarious X-ray images,diagnosing pneumonia has typically proven *** improve image quality and speed up the diagnosis of pneumonia,numerous approaches have been *** date,several methods have been employed to identify *** Convolutional Neural Network(CNN)has achieved outstanding success in identifying and diagnosing diseases in the fields of medicine and ***,these methods are complex,inefficient,and imprecise to analyze a big number of *** this paper,a new hybrid method for the automatic classification and identification of Pneumonia from chest X-ray images is *** proposed method(ABOCNN)utilized theAfrican BuffaloOptimization(ABO)algorithmto enhanceCNNperformance and *** Weinmed filter is employed for pre-processing to eliminate unwanted noises from chest X-ray images,followed by feature extraction using the Grey Level Co-Occurrence matrix(GLCm)*** features are then selected from the dataset using the ABO algorithm,and ultimately,high-performance deep learning using the CNN approach is introduced for the classification and identification of *** results on various datasets showed that,when contrasted to other approaches,the ABO-CNN outperforms them.all for the classification *** proposed method exhibits superior values like 96.95%,88%,86%,and 86%for accuracy,precision,recall,and F1-score,respectively.

关键词： African buffalo optimization convolutional neural network pneumonia X-ray

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Numerical Treatments for Crossover Cancer model of Hybrid Variable-Order Fractional Derivatives

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Computer modeling in Engineering & Sciences 2024年第8期140卷 1619-1645页

作者： Nasser Sweilam Seham.al-mekhlafi Aya ahmed Ahoud alsheri Emad Abo-Eldahab mathematics Department Faculty of ScienceCairo UniversityGiza12613Egypt mathematics Department Faculty of EducationSana’a UniversitySana’a1247Yemen mathematics Department Faculty of ScienceHelwan UniversityCairo11795Egypt Department of mathematics College of ScienceUniversity of BishaAl Namas67398-5644Saudi Arabia

In this paper,two crossover hybrid variable-order derivatives of the cancer model are ***ünwald-Letnikov approximation is used to approximate the hybrid fractional and variable-order fractional *** existence,uniqueness,and stability of the proposed model are *** Bashfourth’s fifth-step method with a hybrid variable-order fractional operator is developed to study the proposed *** studies with generalized fifth-order Runge-Kutta method are *** examples and comparative studies to verify the applicability of the used methods and to demonstrate the simplicity of these approximations are *** have showcased the efficiency of the proposed method and garnered robust empirical support for our theoretical findings.

关键词： Cancer diseases hybrid variable-order fractional derivatives adams bashfourth fifth step generalized fifth order Runge-Kutta method

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EDSUCh:A robust ensemble data summarization method for effective medical diagnosis

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Digital Communications and Networks 2024年第1期10卷 182-189页

作者： mohiuddin ahmed A.N.m.Bazlur Rashid School of Science Edith Cowan UniversityPerthAustralia

Identifying rare patterns for medical diagnosis is a challenging task due to heterogeneity and the volume of *** summarization can create a concise version of the original data that can be used for effective *** this paper,we propose an ensemble summarization method that combines clustering and sampling to create a summary of the original data to ensure the inclusion of rare *** the best of our knowledge,there has been no such technique available to augment the performance of anomaly detection techniques and simultaneously increase the efficiency of medical *** performance of popular anomaly detection algorithms increases significantly in terms of accuracy and computational complexity when the summaries are ***,the medical diagnosis becomes more effective,and our experimental results reflect that the combination of the proposed summarization scheme and all underlying algorithms used in this paper outperforms the most popular anomaly detection techniques.

关键词： Data summarization Ensemble medical diagnosis Sampling

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