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Botulinum Toxin Type A Satisfaction in Different Neurological Disorders

Neuroscience & Medicine 2022年第1期13卷 1-16页

作者： Jasem Yousef Al-Hashel Doaa Youssry Soliman Ismail Ibrahim Ismail Samar Farouk ahmed Department of Neurology Ibn Sina Hospital Kuwait City Kuwait Department of Medicine Faculty of Medicine Health Sciences Centre Kuwait University Kuwait City Kuwait Department of Neurology Cairo University Cairo Egypt Department of Neuropsychiatry Faculty of Medicine Minia University Minia Egypt

Background: The botulinum toxin type A (BoNT-A) is used in a wide range of neurological diseases. We aimed to study the overall patients/caregivers’ satisfaction with BoNT-A treatment in different neurological conditions. Methods: Prospective study included patients who had received at least two BoNT-A treatment sessions. They were asked to rate overall treatment satisfaction at the peak of treatment effect on a 1 to 10 scale (1 = not at all satisfied;10 = fully satisfied). Subjects with a rating of 1to3 were classified as not at all satisfied, those with a rating of 4 to7 as somewhat satisfied, and those with a rating of 8 to10 as very satisfied. Treatment satisfaction questionnaire for medicine (TSQM) was assessed at the end of observational period. Quality of life QOL was assessed before BoNT-A treatment and at the last visit. Results: The study was conducted from first April 2014 to August 2021. 548 patients were identified with mean age 43.66 ± 14.50. Most of participants 389 (71%) were female. At the end of observational period, the mean satisfaction was 7.28 ± 1.78. There was a highly significant difference (P P P = 0.001). Conclusion: Satisfaction with BoNT-A therapy for different neurological disorders is overall good. The highest patient satisfaction was observed with primary focal HH, and the least satisfaction was observed in writer’s cramp. BoNT-A therapy improved QOL.

关键词： Botulinum Toxin Type A Satisfaction Headache Dystonia Movement Disorders Hyperhidrosis

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Measuring Audit Firms＇ Intellectual Capital as a Determinant of Audit Quality： A Suggested Model

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Journal of Modern Accounting and Auditing 2014年第1期10卷 59-79页

作者： Amr N. Abdelrhman Khaled Z. Labib ahmed F. Elbayoumi Cairo University Cairo Egypt Cairo University Cairo EgyptThe American University in Cairo Cairo Egypt

The intellectual capital is a main source of competing advantage. Many studies developed measure（s） of intellectual capital of industrial and service firms. Few studies have tried to develop a reliable measure of intellectual capital in audit firms. This study extends the current models to provide more insight into the role of intellectual capital in audit firms. The aim of this study is to develop a quantitative model to measure audit firms＇ intellectual capital. The suggested model can be used to explore the relationship between the intellectual capital in audit firms and audit quality. The model combines the main components of intellectual capital （human capital, structural capital, and relational capital）. The suggested model provides a tool that may help to better manage the intellectual capital in audit firms. As this is a theoretical study, a number of hypotheses are presented for testing in the future.

关键词： intellectual capital human capital structural capital relational capital audit quality audit firms

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The Gravitomagnetic and Field Magnetic Centrifugal Force Using Force and Four-Dimensional Potential Concepts

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Natural Science 2022年第3期14卷 125-132页

作者： Mohamed Yahia Shirgawi Zoalnoon ahmed Abeid Allah Saad Mubarak Dirar Abd-Alla Yagoub Department of Physics Faculty of Art and Science at Al Muznab Al Qassim University Buraydah Saudi Arabia Department of Physics Faculty of Arts and Sciences at Dhahran Aljanoub King Khalid University Abha Saudi Arabia Department of Physics Faculty of Science Sudan University of Science and Technology Khartoum Sudan

Unification of fundamental forces is the dream of physics. Nevertheless, unfortunately gravitational force operators to be isolated in its geometrical content from other forces. This encourages some researchers to propose the so-called gravimagnetic field to unify gravity with other forces and to explain some cosmological problems at the early universe. This motivates to construct a new model to confirm the existence of gravitomagnetic and a corresponding magnetic field associated with any field. Using the formal Newton definition of force and considering the magnetic force to be related to the time varying mass, the magnetic force is shown to be equal to the centrifugal force. This equality is typical when treating a particle as string. Using also the definition of force in terms of potential and electric force only, energy is shown to be conserved. The Newton force can be defined also in terms of four-dimensional potential with the time varying part related to the magnetic potential. When the particle is treated as a string, energy conservation holds, while for ordinary particle, the Lagrangian is conserved. The energy conservation holds for special relativity also for energy per unit mass. The definition of acceleration for forces that obeys inverse square law shows also the magnetic force is equal to the centrifugal force.

关键词： Gravitomagnetic Force Magnetic Force Newton Force Special Relativity Centrifugal Force Energy Lagrangian

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First-Order Studies of Nanometric Biferroic

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World Journal of Condensed Matter Physics 2012年第2期2卷 66-74页

作者： M. A. ahmed U. Seddik N. G. Imam Materials Science Lab.(1) Physics Department Faculty of Science Cairo University Giza Egypt Physics Department Nuclear Research Center Atomic Energy Authority Cairo Egypt

Magnetoelectric biferroic nanocomposite with composition 0.5Ni0.5Zn0.5Fe2O4 + 0.5BaTiO3 was synthesized by ceramic technique. The structural and electrical characterizations of the investigated nanocomposite are discussed and reported. The formation of nanosized composite with two separate phases was confirmed by X-ray diffraction, scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FT-IR). The variation of dielectric constant (ε'), dielectric loss factor (ε') and the ac conductivity (σac) of 0.5Ni0.5Zn0.5Fe2O4 + 0.5BaTiO3 was investigated as a function of both frequency and temperature. Thermal hysteresis (first-order transition) was obtained during heating (300 - 830 K) and cooling runs (830 - 300 K). The exact transition temperature and the amount area of the thermal hysteresis depend on applied ac electric field. The delay (lagging) time between heating and cooling processes was esti-mated from the hysteresis loop area versus frequency. The conduction mechanism in the investigated samples was explained according to different models. This study enhances the use of this prepared system in memory applications.

关键词： Biferroic Nanocomposite Nickel-Zinc Ferrite Barium Titanate Dielectric Hysteresis First-Order Transition

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Efficacy of therapeutic ultrasound vs sham ultrasound on pain and physical function in people with knee osteoarthritis: A meta-analysis of randomized controlled trials

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World Journal of Meta-Analysis 2014年第3期2卷 78-90页

作者： Norma J Mac Intyre ahmed Negm Adalberto Loyola-Sánchez Mohit Bhandari School of Rehabilitation Science Mc Master UniversityHamilton Department of Surgery Mc Master UniversityHamilton

AIM: To determine the efficacy of therapeutic ultrasound vs sham for improving pain and physical function immediately post-intervention in people with knee osteoarthritis(OA). METHODS: We hand searched meta-analyses on the topic published in 2010 and updated the search in three electronic databases(MEDLINE, EMBASE, CINAHL) January 1, 2009 to September 5, 2013 to identify relevant studies. The inclusion criteria were human randomized controlled trials published in the English language in which active therapeutic ultrasound was compared tosham ultrasound, data for people with knee OA were reported separately, participants were blinded to treatment allocation and outcomes assessed before and after treatment included pain, self-reported physical function and performance-based physical function. Two reviewers independently screened titles and abstracts retrieved in the search to identify trials suitable for full text review. Data extraction and risk of bias assessment of the identified trials were completed independently by two reviewers. Pooled analyses were conducted using inverse-variance random effects ***: We screened 1013 titles and abstracts. Meta-analysis of pain outcomes from 5 small trials(281 participants/OA knees) showed that, compared to sham ultrasound, therapeutic ultrasound improves pain [standardized mean difference(SMD)(95%CI) =-0.39(-0.70--0.08); P = 0.01] but not physical function [self-reported in 3 trials(130 participants/OA knees): SMD(95%CI) =-0.21(-0.55-0.14), P = 0.24; walking performance in 4 trials(130 participants/OA knees): SMD(95%CI) =-0.11(-0.59-0.37), P = 0.65). For the walking performance outcome, the dispersion of the estimated effects exceeded that expected due to sampling error(χ2 = 8.37, P = 0.04, I 2 = 64%). Subgroup analyses of three trials that administered high dose ultrasound improved the consistency(I2 = 28%) but the treatment effect remained ***: Meta-analyzed double-blind placebocontrolled rand

关键词： Ultrasonic therapy Physical therapy modalities Osteoarthritis Double-blind method Evidence-based medicine

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Study on Deformation of Lattice Sandwich Structure Subjected to Uniform Water Pressure

Study on Deformation of Lattice Sandwich Structure Subjected...

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第十二届武汉地区船舶与海洋工程研究生学术论坛

作者： Tauhid ahmed Zhang Zhenhua Deng Bo Huang Xiufeng Naval University of Engineering College of naval architecture and ocean engineering

Sandwich panels composed of pyramidal cellular cores and solid face plates are presented to high hydrostatic pressure. The performance of this hybrid composite structure under high hydrostatic pressure is numerically studied, considering the geometric variations of the lattice core. The panels were assumed to be made from marine grade ductile stainless steel. Different design parameters were considered, including material properties, thickness of face plate, and diameter of the unit cell strut member. The structures responses were compared to those of monolithic solid plates of equivalent weight. The hydrostatic pressure given to the sandwich panels was varied up to 10 MPa s by changing the operating water depth of the structure. A decoupled finite element model has been used to computationally study the quasi-static response of the structures. The model predicts structural deformations quite well and is used to identify the deformation sequence during changing depth and the face plate and core failure mechanisms. Optimally designed sandwich plates can sustain hydrostatic pressures with two to three times smaller deformations than the monolithic plates of the same mass and material. The model is used to discuss several issues relevant to the design of effective pyramidal sandwich plates, including differing radius and thickness of plates and core materials, the role of core strength, and the relation between sandwich plates and same weight monolithic solid plates.

关键词： Lattice materials Finite element analysis Plastic buckling Sandwich panels Hydrostatic pressure

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De novo glomerular diseases after renal transplantation:How is it different from recurrent glomerular diseases?

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World Journal of Transplantation 2017年第6期7卷 285-300页

作者： Fedaey Abbas Mohsen El Kossi Jon Kim Jin Ajay Sharma ahmed Halawa Department of Nephrology Jaber El Ahmed Military Hospital Faculty of Health and Science University of LiverpoolInstitute of Learning and TeachingSchool of Medicine Doncaster Royal Infirmary Nottingham Children Hospital Royal Liverpool University Hospitals Department of Transplantation Surgery Sheffield Teaching Hospitals

The glomerular diseases after renal transplantation can occur de novo,i.e.,with no relation to the native kidney disease,or more frequently occur as a recurrence of the original disease in the native *** may not be any difference in clinical features and histological pattern between de novo glomerular disease and recurrence of original glomerular ***,structural alterations in transplanted kidney add to dilemma in *** changes in architecture of histopathology can happen due to:(1) exposure to the immunosuppression specifically the calcineurin inhibitors(CNI);(2) in vascular and tubulointerstitial alterations as a result of antibody mediated or cellmediated immunological onslaught;(3) post-transplant viral infections;(4) ischemia-reperfusion injury; and(5) hyperfiltration *** pathogenesis of the de novo glomerular diseases differs with each *** of B-cell clones with subsequent production of the monoclonal Ig G,particularly Ig G3 subtype that has higher affinity to the negatively charged glomerular tissue,is suggested to be included in PGNMID *** novo membranous nephropathy canbe seen after exposure to the cryptogenic podocyte *** role of the toxic effects of CNI including tissue fibrosis and the hemodynamic alterations may be involved in the de novo FSGS *** well-known deleterious effects of HCV infection and its relation to MPGN disease are frequently *** new concepts have emerged that demonstrate the role of dysregulation of alternative complement pathway in evolution of MPGN that led to classifying into two subgroups,immune complex mediated MPGN and complement-mediated *** latter comprises of the dense deposit disease and the C3 GN *** novo C3 disease is rather *** of de novo diseases varies with each type and their management continues to be empirical to a large extent.

关键词： De novo glomerulonephritis Renal transplantation New concepts of therapy

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Presentation and Management of Wilm’s Tumour in Sudan (Three Centre Experience from 2014-2016)

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Open Journal of Urology 2021年第10期11卷 358-366页

作者： ahmed Mohammed Atiaallah Mutaz Ogeal Osman Aamir Abdallah Hamza Mawadda Farah Omer Alamin Faculty of Medicine Red Sea University Port Sudan Sudan Faculty of Medicine University of Bahri Khartoum Bahri Sudan Sudan Medical Specializations Board Khartoum Sudan National Elribat University Hospital Khartoum Sudan

Background: Wilm’s tumour is a cancer of the kidneys that typically occurs in children younger than fifteen years of age and rarely in adults. With an early diagnosis and proper management of Wilm’s tumour by Multi-modal approach, excellent outcome can be obtained. This study was designed to reflect the clinical presentations and focus on different management modalities with an outcome of Wilm’s tumour in Sudan. Patients and methods: This descriptive, retro-prospective analytic study included all patients of Wilm’s tumour at Soba University Hospital, Gezira national paediatric surgery centre and Khartoum teaching Hospital from January 2014 to January 2016. Results: Thirty patients (pts) were included. Females were predominant in a ratio of 3: 1 to males. The mean age was 3.0 - 5.9 years. Those who came from central and western of Sudan were more affected. Most patients presented with abdominal mass 28 pts (93.3%), followed by abdominal distension in 16 pts (53.3%), while the less frequent presentation was haematuria seen only in 2 pts (6.7%). The multimodal approach: surgery and chemotherapy used in 21 pts (70%) and single modality was used in nine patients: surgery alone in 6 pts (20%), or chemotherapy alone in 3 pts (10%). The patients discharged uneventfully 23 pts (76%). Morbidity was seen in two patients. Deaths were occurred in five patients in the study (16.7%). Conclusion: The finding of this study reflected that Wilm’s tumour has an excellent outcome when patient was managed by multimodal approach.

关键词： Wilm’s Tumour Multi-Modal Approach Nephrectomy Chemotherapy Outcome

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Estimating the severity levels of road traffic crashes in Bahrain with crash costs estimated with different approaches

Digital Transportation and Safety

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Digital Transportation and Safety 2023年第4期2卷 278-283页

作者： Uneb Gazder Ashar ahmed Bashayer Habib Abdulhusain Asrar Hassan Mohamed Nedal Ratrout Department of Civil Engineering College of EngineeringUniversity of BahrainBahrainPO Box 32038 Isa TownKingdom of Bahrain Department of Urban and Infrastructure Engineering NED University of Engineering and TechnologyKarachi75270Pakistan Department of Civil Engineering King Fahd University of Petroleum and MineralsDhahran31261Kingdom of Saudi Arabia

An important issue in analyzing accident blackspots is the estimation of severity levels of different types of *** study aims to estimate the severity level of accidents in Bahrain using crash *** crash costs were calculated by the Human Capital Approach(HCA)and total reported costs from the *** data was collected from the General Directorate of Traffic,insurance companies,Ministry of Works(MoW)and Ministry of *** was found,from the survey responses,that there was no significant effect of victim characteristics on the total cost of the *** severity levels were found to be higher than those found in previous literature or adopted by local authorities which could be attributed to the economic conditions of ***,the weights found by both approaches were different from each ***,it is recommended to use the HCA approach due to its comprehensive calculations involving future costs.

关键词： Crash severity levels Cost of accidents Human capital approach Reported costs

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Characterisation for <i>Radioelements</i>over an Escarpment Feature(S): A Case Study of the Duku-Tarasa Gwandu Ridge Area of Birnin Kebbi NW Nigeria

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International Journal of Geosciences 2020年第8期11卷 529-543页

作者： A. Adamu O. Ologe A. L. ahmed A. Y. Sunusi Department of Applied Geophysics Federal University Birnin Kebbi Birnin Kebbi Nigeria Department of Physics Ahmadu Bello University Zaria Nigeria Department of Physics Usmanu Danfodio University Sokoto Nigeria

The paper presents results of radiometric investigations of an area (Duku-Tarasa) near the capital city of the State of Birnin Kebbi, NW Nigeria. The area of study is about 440 m × 420 m and encloses an Escarpment Feature/Structure on a sedimentary rock generally referred to as the Gwandu Formation. The Gwandu Formation (though not described in the paper) consists of continental lacustrine sediments and is the youngest Palaeogene Formation present in the Sokoto sector of the larger Iullemmeden Basin. The study measured, along some selected profiles across this escarpment feature, radiometric signatures using a Sim-Max G411 portable field gamma-ray spectrometer (giving counts for U, Th and K relative to the background values over the area), the ground total-field magnetic data (using the proton precession magnetometer) along those profiles and collected some (5) rock samples for flame photometry and AAS analyses towards the target proposition. Activity concentration levels due to potassium (K), uranium (U) and thorium (Th) were measured in the area along the five established profiles spaced at 50 metres. The results from these measurements and analyses were displayed (in Tables/histograms and gray level maps/images of concentrations of Uranium, Thorium and Potassium prospects) and interpreted (dismissing the magnetic data as seemingly passive as no filter was applied to the mapped data).

关键词： Gwandu Ridge Iso-Radiometric Contour Map Gamma Activity Gamma-Ray Spectrometry and Radioelements

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