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Challenges to establishing and maintaining kidney transplantation programs in developing countries:What are the coping strategies?

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World Journal of Methodology 2024年第2期14卷 1-16页

作者： Rabea ahmed Gadelkareem Amr Mostafa Abdelgawad Nasreldin Mohammed Mohammed ali Zarzour Mahmoud Khalil ahmed Reda Hisham Mokhtar Hammouda Department of Urology Assiut Urology and Nephrology HospitalFaculty of MedicineAssiut UniversityAssiut 71515Egypt

Kidney transplantation(KT)is the optimal form of renal replacement therapy for patients with end-stage renal ***,this health service is not available to all patients,especially in developing *** deceased donor KT programs are mostly absent,and the living donor KT centers are ***-center studies presenting experiences from developing countries usually report a variety of *** review addresses these challenges and the opposing strategies by reviewing the single-center experiences of developing *** financial challenges hamper the infrastructural and material availability,coverage of transplant costs,and qualification of medical *** sociocultural challenges influence organ donation,equity of beneficence,and regular follow-up *** interests and motives for transplantation may result from high medicolegal responsibilities in KT practice,intense potential psychosocial burdens,complex qualification protocols,and low productivity or compensation for KT *** medical literacy about KT advantages is prevalent among clinicians,patients,and the *** inefficient organizational and regulatory oversight is translated into inefficient healthcare systems,absent national KT programs and registries,uncoordinated job descriptions and qualification protocols,uncoordinated on-site investigations with regulatory constraints,and the prevalence of commercial KT *** challenges resulted in noticeable differences between KT services in developed and developing *** coping strategies can be summarized in two main mechanisms:The first mechanism is maximizing the available resources by increasing the rates of living kidney donation,promoting the expertise of medical personnel,reducing material consumption,and supporting the establishment and maintenance of KT *** latter warrants the expansion of the public sector and the elimination of non-ethical KT *** second mechanism is recru

关键词： Challenges Coping strategies Developing countries Kidney transplantation Low resources Single-center

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Updates on management of gliomas in the molecular age

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World Journal of Clinical Oncology 2024年第2期15卷 178-194页

作者： ali ahmed Mohamed Rakan Alshaibi Steven Faragalla Youssef Mohamed Brandon Lucke-Wold Charles E.Schmidt College of Medicine Florida Atlantic UniversityBoca RatonFL 33431United States Herbert Wertheim College of Medicine Florida International UniversityMiamiFL 33199United States College of Osteopathic Medicine Kansas City UniversityJoplinMO 64804United States Department of Neurosurgery University of FloridaGainesvilleFL 32611United States

Gliomas are primary brain tumors derived from glial cells of the central nervous system,afflicting both adults and children with distinct characteristics and therapeutic *** developments have ushered in novel clinical and molecular prognostic factors,reshaping treatment paradigms based on classi-fication and grading,determined by histological attributes and cellular *** review article delves into the diverse treatment modalities tailored to the specific grades and molecular classifications of gliomas that are currently being discussed and used clinically in the year *** adults,the therapeutic triad typically consists of surgical resection,chemotherapy,and *** contrast,pediatric gliomas,due to their diversity,require a more tailored *** complete tumor excision can be curative based on the location and grade of the glioma,certain non-resectable cases demand a chemotherapy approach usually involving,vincristine and ***-tionally,if surgery or chemotherapy strategies are unsuccessful,Vinblastine can be *** recent advancements in treatment methodologies,there remains a need of exploration in the literature,particularly concerning the efficacy of treatment regimens for isocitrate dehydrogenase type mutant astrocytomas and fine-tuned therapeutic approaches tailored for pediatric *** review article explores into the therapeutic modalities employed for both adult and pediatric gliomas in the context of their molecular classification.

关键词： Gliomas Chemotherapy Radiotherapy Isocitrate dehydrogenase type mutant Pediatric gliomas Astrocytoma Oligodendroglioma 1p/19q-codeleted

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Acute Transverse Myelitis in Pregnancy—A Case Report and a Literature Review

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Open Journal of Obstetrics and Gynecology 2024年第9期14卷 1512-1521页

作者： Huda Abbas ali Isa Fatema Hasan Zainab Mohd Al Aswad Naeema ahmed Abdulkareem Salmaniya Medical Complex Manama Bahrain Ob Gyn Faculty Arabian Gulf University Manama Bahrain

Purpose: This case report highlights a rare instance of a 26-week pregnant woman presenting with limb numbness, diagnosed with acute transverse myelitis (ATM) following COVID-19 vaccination. Notably, she tested positive for neuromyelitis optica (NMO) but did not exhibit the typical symptoms of blurred vision. Methods: Data were collected from I Seha in governmental hospitals in Bahrain, providing a comprehensive overview of the patient’s clinical journey. Results: The patient was treated with carbamazepine, steroids, and clexane, leading to the successful delivery of a healthy baby at 34 weeks. However, two years postpartum, she reported new episodes of blurred vision and numbness. Subsequent treatment with Rituximab resulted in significant improvement, with a diagnosis of Devic’s disease established. Conclusion: Acute transverse myelitis is a rare condition, particularly during pregnancy, and in this case, symptoms of Devic’s disease were masked by the absence of blurred vision. This condition predominantly affects females in their 20s during childbearing years and can lead to complications such as premature delivery. Effective management includes steroids and antiepileptic drugs, with clexane playing a crucial role in preventing embolisms. A delivery mode may vary based on obstetric factors, and MRI remains the gold standard for diagnosis. Close follow-up is essential for optimal patient outcomes.

关键词： Acute Transverse Myelitis (ATM) COVID-19 Devic’s Syndrome Neuromyelitis Optica (NMO) Obstetric Management of ATM

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Impact of non-alcoholic fatty liver disease on coronavirus disease 2019: A systematic review

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World Journal of Hepatology 2024年第8期16卷 1185-1198页

作者： Abdul Moeed Muhammad Omar Larik Muhammad ahmed ali Fahim Hafsah alim Ur Rahman Lubna Najmi Mah I Kan Changez Muhammad Moiz Javed Md Al Hasibuzzaman Department of Internal Medicine Dow University of Health SciencesKarachi 74200SindhPakistan Department of Internal Medicine Dow International Medical CollegeKarachi 74200SindhPakistan Department of Internal Medicine Ziauddin UniversityKarachi 75000SindhPakistan Department of Research Yale UniversityNew Haven 06520CTUnited States Department of Internal Medicine King Edward Medical UniversityLahore 54000PunjabPakistan Institute of Nutrition and Food Science University of DhakaDhaka 1000Bangladesh Department of Medicine The Affiliated Hospital of Medical School of Ningbo UniversityNingbo 315211Zhejiang ProvinceChina

BACKGROUND Many studies have revealed a link between non-alcoholic fatty liver disease(NA-FLD)and coronavirus disease 2019(COVID-19),making understanding the relationship between these two conditions an absolute *** To provide a qualitative synthesis on the currently present data evaluating COVID-19 and *** This systematic review was conducted in accordance with the guidelines pro-vided by preferred reporting items for systematic reviews and meta-analyses and the questionnaire utilized the population,intervention,comparison,and outcome *** search strategy was run on three separate databases,PubMed/MEDLINE,Scopus,and Cochrane Central,which were systematically searched from inception until March 2024 to select all relevant *** addition,***,***,and Google Scholar were searched to identify grey *** After retrieval of 11 studies,a total of 39282 patients data were *** was found in 11.5%and 9.4%of people in NAFLD and non-NAFLD *** all,23.2%of NAFLD patients and 22%of non-NAFLD admissions diagnosed with COVID-19 were admitted to the intensive care unit,with days of stay *** support ranged from 5%to 40.5%in the NAFLD cohort and from 3.1%to 20%in the non-NAFLD *** incidence of acute liver injury showed *** improvement on days 7 and 14 between the two classifications was *** stay ranged from 9.6 days to 18.8 days and 7.3 days to 16.4 days in the aforementioned cohorts respectively,with 73.3%and 76.3%of patients being *** rates *** Clinical outcomes except mortality consistently showed a worsening trend in patients with NAFLD and concomitant *** research in conducting prospective longitudinal studies is essential for a more powerful conclusion.

关键词： Non-alcoholic fatty liver disease Coronavirus disease 2019 Mechanical ventilation Intensive care unit Acute liver injury

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Evaluation of the Strategy and Efficacy of Treatment of Chronic Viral Hepatitis C with the Sofosbuvir/Daclatasvir Combination in a Resource-Limited Country

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Open Journal of Gastroenterology 2024年第7期14卷 233-240页

作者： Mayanna Habkreo ali Mahamat Moussa Adama ahmed Ngare Abdraman Kossou Tahir Mahamat Saleh Maire Dehainsala Mahamat ali Hachim Mahamat ali Bolti Oumaima Djarma Joseph Madtoingue Service de Gastroentrologie/Mdecine Interne du Centre Hospitalier Universitaire la Rfrence Nationale NDjamena Chad Service de Gastroentrologie du Centre Hospitalier Universitaire la Renaissance NDjamena Chad Service de Maladies Infectieuses du Centre Hospitalier Universitaire la Renaissance NDjamena Chad Service de Maladies Infectieuses du Centre Hospitalier Universitaire la Rfrence Nationale NDjamena Chad

Introduction: The treatment of viral hepatitis C (HCV), a major public health problem, has evolved considerably since the introduction of direct-acting anti-virals (DAAs). The aim of this study was to evaluate the strategy for initiating treatment with Sofosbuvir/Daclatasvir, and also to assess its efficacy. Patients and Methods: Included were patients aged at least 15 years, with detectable hepatitis C viremia and treated with a pan-genotypic Sofosbuvir/Daclatasvir regimen at the Centre “Hospitalier Universitaire la Référence Nationale de N’Djamena” between October 2019 and October 2023. The APRI score was used to assess fibrosis. Cure was defined by an undetectable viral load 12 weeks after the end of treatment. Results: A total of 835 patients were included (sex ratio 1.55, mean age 50.5 ± 13.73, extremes 20 and 84 years). The 60 - 69 age group was the most represented. The mean APRI score was 0.42 ± 0.29, with extremes of 0.019 and 1.84. The mean viral load was 2,316,193.086 IU/mL. All subjects had good renal function. Cytolysis was absent in 70% of cases. Without genotyping, a pan-genotypic regimen was used in all patients: Sofosbuvir (400 mg)/Daclatasvir (60 mg). The cure rate was 99.4%, with good tolerability. However, four cases of failure were recorded out of the 668 patients who underwent follow-up HCV-PCR testing after 12 weeks of treatment. Conclusion: The Sofosbuvir/Daclatasvir regimen is highly effective, with an excellent safety profile. However, the still high cost of these molecules limits their accessibility to a large proportion of patients.

关键词： Efficacy Tolerance Sofosbuvir/Daclatasvir HCV Chad

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Mapping lineaments using Landsat 8 OLI and SRTM data;a case study of the eastern part of the Ouarzazate Basin,Morocco

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Journal of Mountain Science 2024年第3期21卷 987-1003页

作者： MOUJANE Said ALGOUTI ahmed ALGOUTI Abdellah FARAH Abdelouahed ABOULFARAJ Abdelfatah NAFOURI Imane Geoscience Geotourism Natural Hazards and Remote Sensing Laboratory(2GRNT) Department of GeologyFaculty of Sciences SemlaliaUniversity of Cadi AyyadBP 239040000MarrakechMorocco

The integration of remote sensing and geographic information system(GIS)was employed in this study to delineate the structural lineaments within the eastern section of the Ouarzazate Basin,situated between the southern front of the Central High Atlas and the northern slopes of the Eastern Anti-Atlas(also known as the Saghro Massif).To achieve this objective,Landsat 8 Operational Land Imager(OLI)and Shuttle Radar Topography Mission(SRTM)data were *** Component Analysis(PCA)was computed and a directional filter was applied to the first PCA and the panchromatic band(B8).Additionally,shading was applied to the SRTM data in four directions;N0°,N45°,N90°,N135°.After removing of the non-geological linear structures,the results obtained,using the automatic extraction method,allowed us to produce a synthetic map that included 1251 lineaments with an average length of 1331 m and was dominated by NE-SW,ENE-WSW and E-W directions,***,the high lineament density is clearly noted in the Anti-Atlas(Saghro Massif)and at the level of the northern part,extending from the Ait Ibrirne to Arg-ali Oubourk *** lineament density can always be found around the major faults affecting this *** data collected during the field investigations and from geological maps show that the major direction of the faults and structural accidents range mostly between N45°,N70°and N75°.The correlation of remote sensing results with those collected in the field shows a similarity and coincidence with each *** these results,it is possible to consider the automatic extraction method as a supplementary kind that can serve classical geology by quickly enriching it with additional *** shown in this work,this method provides more information when applied in arid areas where the fields are well outcropped.

关键词： Remote sensing GIS Landsat 8 OLI SRTM Ouarzazate Basin Central High Atlas

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Prevalence of Occupational Injury and Knowledge of Post-Exposure Prophylaxis Accessibility among Healthcare Workers in Mogadishu, Somalia

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Occupational Diseases and Environmental Medicine 2024年第3期12卷 172-198页

作者： Yonis Abdullahi ahmed Anshur Abdishakur Mohamud Sheik Miski Abdullahi Roble Abdullahi Mohamed Yasin Abdullahi ali Mohamed Fardowso ali Mohamud Abdimalik Dahir Abdi Ikran Abdullahi Isse Warda Adan Ibrahim Mohamed Jimale Adan Ugbad ahmed Daud ahmed Aweis Abdullahi Mohamed Hassan Fujeyra College of Medicine and Health Science Abrar University Mogadishu Somalia Directorate of Health-Banadir Regional Administration Mogadishu Somalia Mogadishu Somali Trkiye Training and Research Hospital Mogadishu Somalia Department Faculty of Medicine and Surgery Zamzam University of Science and Technology Mogadishu Somalia Banadir Maternity and Childhood Hospital Mogadishu Somalia Department Faculty of Medicine and Surgery Banadir University Mogadishu Somalia Faculty of Medicine & Surgery Somali National University Mogadishu Somalia

Introduction: Healthcare workers in Mogadishu, Somalia face significant occupational injury risks, particularly needle stick injuries, with 61.1% reporting incidents. This poses a serious threat to their health, leading to infections such as hepatitis B, hepatitis C, and HIV. Despite the high prevalence of injuries, awareness of Post-Exposure Prophylaxis (PEP) accessibility is relatively high, with 84.0% of respondents aware of it. However, there are gaps in knowledge and implementation, as evidenced by variations in availability of PEP. Improving workplace safety measures, providing comprehensive training on injury prevention and PEP protocols, and ensuring consistent availability of PEP in healthcare facilities are crucial steps to safeguard the well-being of healthcare workers in Mogadishu, Somalia. Methods: A cross-sectional study was conducted among hospital workers in Mogadishu, Somalia, focusing on professionals from various healthcare facilities. The study targeted nurses, doctors, laboratory personnel, and pharmacists. Purposive sampling was employed, resulting in a sample size of 383 calculated using Fisher’s sample size formula. Data were collected using coded questionnaires entered into Microsoft Excel 2019 and analyzed with SPSS software to generate frequencies and proportions, presented through frequency tables and pie figures. Results: The study in Mogadishu, Somalia, examined the prevalence of occupational injuries and knowledge of Post-Exposure Prophylaxis (PEP) accessibility among healthcare workers. Findings indicate a high prevalence of injuries, with 61.1% reporting incidents, predominantly needle stick injuries (60.6%). Despite the majority seeking prompt medical attention (72.0%), work-related illnesses affected 53.2% of respondents, notably work-related stress (59.5%). While most received training on injury and illness prevention (68.9%), gaps exist in PEP awareness, with 16.0% unaware of it. Nonetheless, 84.0% were aware, predominantly throu

关键词： Prevalence of Occupational Injury Post-Exposure Prophylaxis (PEP) Accessibility Healthcare Workers Needle Stick Injuries Infections (Hepatitis B Hepatitis C HIV) Awareness Knowledge Workplace Safety PEP Availability Blood-Borne Diseases Personal Protective Equipment (PPE) HIV PEP (Post-Exposure Prophylaxis)

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Endoscopic Transcanal Excision of Glomus Tympanicum: A Case Report and Literature Review

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International Journal of Otolaryngology and Head & Neck Surgery 2024年第5期13卷 305-310页

作者： Mohammed Atiah Alzahrani Yahia Dhafer Alahmari ali Jaber Asiry Ibrahem Hamad Erwe Ghada ahmed Bin Abbas Department of Otorhinolaryngology Aseer Central Hospital Abha Saudi Arabia College of Medicine University of King Khalid Abha Saudi Arabia

Glomus tumors are extremely rare tumors that arise from paraganglionic cells, which are derived from neural crest cells. These tumors are benign, slow-growing, locally invasive, and destructive. Glomus tumors are the most common tumor of the middle ear cavity and the second most common tumor of the temporal bone. We present a case of a 49-year-old healthy female who, following diagnostic tools, received surgical intervention resulting in an excellent outcome. Our case report includes a comprehensive analysis of published cases in the literature.

关键词： Glomus Tympanicum Paragangliomas Endoscopic Transcanal

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An Electrical Impedance Imaging System Towards Edge Intelligence for Non-Destructive Testing of Concrete

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Tsinghua Science and Technology 2024年第3期29卷 883-896页

作者： Abolfazl Roshanpanah Mahdi Abbasi Hani Attar Ayman Amer Mohammad R.Khosravi ahmed A.Solyman Department of Electrical Engineering Islamic Azad UniversityScience and Research BranceTehran ***Iran Department of Computer Engineering Bu-Ali Sina UniversityHamedan ***Iran Department of Energy Engineering Zarqa UniversityZarqa 13110Jordan Department of Computer Engineering Persian Gulf UniversityBushehr ***Iran Department of Electrical and Electronics Engineering Faculty of Engineering and ArchitectureNişantaşıUniversityIstanbul 34398Turkey

In the construction industry,to prevent accidents,non-destructive tests are necessary and *** impedance tomography is a new technology in non-invasive imaging in which the image of the inner part of conductive bodies is reconstructed by the arrays of external electrodes that are connected on the periphery of the *** equipment is cheap,fast,and edge *** this imaging method,the image of electrical conductivity distribution(or its opposite;electrical impedance)of the internal parts of the target object is *** image reconstruction process is performed by injecting a precise electric current to the peripheral boundaries of the object,measuring the peripheral voltages induced from it and processing the collected *** an electrical impedance tomography system,the voltages measured in the peripheral boundaries have a non-linear equation with the electrical conductivity *** paper presents a cheap Electrical Impedance Tomography(EIT)instrument for detecting impurities in the concrete.A voltage-controlled current source,a micro-controller,a set of multiplexers,a set of electrodes,and a personal computer constitute the structure of the *** conducted tests on concrete with impurities show that the designed EIT system can reveal impurities with a good accuracy in a reasonable time.

关键词： non-destructive testing system concrete electrical impedance tomography

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Analyzing the Impact of Scene Transitions on Indoor Camera Localization through Scene Change Detection in Real-Time

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Intelligent Automation & Soft Computing 2024年第3期39卷 417-436页

作者： Muhammad S.Alam Farhan B.Mohamed ali Selamat Faruk ahmed AKM B.Hossain Department of Emergent Computing School of ComputingUniversiti Teknologi MalaysiaJohor Bahru81310Malaysia Malaysia-Japan International Institute of Technology(MJIIT) Universiti Teknologi MalaysiaKuala Lumpur54100Malaysia Media and Game Innovation Centre of Excellence(MaGICX) Universiti Teknologi MalaysiaJohor Bahru81310Malaysia Department of Engineering Technology University of MemphisMemphisTN38152USA Department of Computer Science and Artificial Intelligence College of Computing and Information TechnologyUniversity of BishaBisha61922Saudi Arabia School of Computing Faculty of EngineeringUniversiti Teknologi MalaysiaJohor Bahru81310Malaysia Department of Information System and Cyber Security College of Computing and Information TechnologyUniversity of BishaBisha61922Saudi Arabia

Real-time indoor camera localization is a significant problem in indoor robot navigation and surveillance *** scene can change during the image sequence and plays a vital role in the localization performance of robotic applications in terms of accuracy and *** research proposed a real-time indoor camera localization system based on a recurrent neural network that detects scene change during the image *** annotated image dataset trains the proposed system and predicts the camera pose in *** system mainly improved the localization performance of indoor cameras by more accurately predicting the camera *** also recognizes the scene changes during the sequence and evaluates the effects of these *** system achieved high accuracy and real-time *** scene change detection process was performed using visual rhythm and the proposed recurrent deep architecture,which performed camera pose prediction and scene change impact ***,this study proposed a novel real-time localization system for indoor cameras that detects scene changes and shows how they affect localization performance.

关键词： Camera pose estimation indoor camera localization real-time localization scene change detection simultaneous localization and mapping(SLAM)

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