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Potential of Plant Growth Regulators on Modulating Rooting of <i>Rosa centifolia</i>

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American Journal of Plant Sciences 2015年第5期6卷 659-665页

作者： Gulzar Akhtar Ahsan Akram Yasar Sajjad Rashad Mukhtar Balal Muhammad Adnan Shahid Hasan Sardar Kaleem naseem Shahid Masood Shah Department of Horticulture University College of Agriculture University of Sargodha Pakistan Department of Environmental Sciences COMSATS Institute of Information Technology Abbottabad Pakistan Institute of Horticultural Sciences University of Agriculture Faisalabad Pakistan

Rosa centifolia is grown for its flowers which are used for essential oil extraction. It is vegetatively propagated through its cuttings which are difficult to root. This study was designed to increase the rooting percentage of cuttings by applying plant growth regulators (PGRs) with different levels. In total 31 treatments with different concentrations (450 ppm, 700 ppm and 950 ppm) of indole butyric acid (IBA), indole acetic acid (IAA), naphthalene acetic acid (NAA) alone, in combination and with same concentrations of 6-benzylamino purine (BAP) were used. Healthy similar sized cutting of R. centifolia was treated in solution of PGRs by quick dip method and planted in polythene bags. The data for shoot length, shoot dry weight, number of roots, root length and root dry weight were recorded. All three levels (450 ppm, 700 ppm and 950 ppm) of IBA alone produced maximum results in case of all parameters as compared to all other treatments. Among three levels of IBA, 450 ppm concentration produced maximum shoot length (10.67 cm), shoot dry weight (3.02 g), number of roots (14.00), root length (11.90 cm) and root dry weight (0.50 g). Lower concentrations of plant growth regulators produced better results as compared to higher concentrations.

关键词： Growth Regulator Rosa centifolia Auxins Rooting Shooting

重组人眼晶状体醛脱氢酶1(ALDH1)的表达和酶动力学研究

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重组人眼晶状体醛脱氢酶1(ALDH1)的表达和酶动力学研究

Pharmacogenomics in colorectal cancer:current role in clinical practice and future perspectives

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作者：肖天林 Ansari H naseem 温州医学院附属眼视光医院德州大学加□斯顿医学分校

目的:醛脱氢酶(Aldehyde Dehydrogenase)可将脂质过氧化毒性代谢产物醛类氧化为相应的酸,从而参与抗脂质过氧化的代谢去毒过程。人眼晶状体主要为ALDH1,我们以前的研究表明ALDH1在晶状体的过氧化产物的代谢去毒中起一定的作用。故研究人...

目的:醛脱氢酶(Aldehyde Dehydrogenase)可将脂质过氧化毒性代谢产物醛类氧化为相应的酸,从而参与抗脂质过氧化的代谢去毒过程。人眼晶状体主要为ALDH1,我们以前的研究表明ALDH1在晶状体的过氧化产物的代谢去毒中起一定的作用。故研究人眼ALDH1的结构与功能学特点具有重要的意义。

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Journal of Cancer Metastasis and Treatment 2018年第1期4卷 146-170页

作者： Francesca Battaglin Alberto Puccini Madiha naseem Marta Schirripa Martin DBerger Ryuma Tokunaga Michelle McSkane Taline Khoukaz Shivani Soni Wu Zhang Heinz-Josef Lenz Division of Medical Oncology Norris Comprehensive Cancer CenterKeck School of MedicineUniversity of Southern CaliforniaLos AngelesCA 90033USA Medical Oncology Unit 1 Clinical and Experimental Oncology DepartmentVeneto Institute of Oncology IOV-IRCCSPadua 35128Italy Department of Medical Oncology University Hospital of BernBern 3010Switzerland

The treatment scenario of colorectal cancer(CRC)has been evolving in recent years with the introduction of novel targeted agents and new therapeutic strategies for the metastatic *** extensive effort has been directed to the identification of predictive biomarkers to aid patients selection and guide therapeutic *** represents an irreplaceable tool to individualize patients treatment based on germline and tumor acquired somatic genetic variations able to predict drugs response and risk of *** growing knowledge of CRC molecular characteristics and complex genomic makeup has played a crucial role in identifying predictive pharmacogenomic biomarkers,while supporting the rationale for the development of new drugs and treatment *** validation of promising biomarkers,however,is often an *** recently,a deeper understanding of resistance mechanisms and tumor escape dynamics under treatment pressure and the availability of novel technologies are opening new perspectives in this *** review aims to present an overview of current pharmacogenomic biomarkers and future perspectives of pharmacogenomics in CRC,in an evolving scenario moving from a single drug-gene interactions approach to a more comprehensive genome-wide approach,comprising genomics and epigenetics.

关键词： Colorectal cancer pharmacogenomics RAS BRAF microsatellite instability dihydropyrimidine dehydrogenase UDP-Glucuronosyltrasferase A1 epidermal growth factor receptor vascular endothelial growth factor DNA methylation

Etiology of Upper GI Bleeding on Endoscopy

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Neuroscience & Medicine 2018年第1期9卷 16-21页

作者： Junaid Khan Muhammad Ali Hareem Bakhsh Sobhi Sheikh Moazzam Waheed Ifrah Shahnawaz Muhammad Abdullah Sardar Muhammad Omer naseem Omer Kamal Farah Bashir Muhammad Nadeem University College of Medicine University of Lahore Lahore Pakistan King Edward Medical University Lahore Pakistan Liaquat University of Medical and Health Sciences Jamshoro Pakistan University at Buffalo Buffalo NY USA

Background: Several circumstances and conditions lead to UGIB. The commonest among them peptic ulcer to an approximation of 50% in cases. The second major cause may be esoghageal varices and third is mallory-weis tears. There are also other causes, which may include erosins, tumors and other malformations like arteriovenous. Methods: This was an observational retrospective study of all patients referred to endoscopy. The study exclusion criteria include all patients who had repeat endoscopies within one month of the previous endoscopy whereas all the patients with UGIB were included in this study. Results: We retrieved data of total 150 patients who had experienced upper gastrointestinal endoscopy during the selected time period covered in the study, March 2015 to February 2016. The mean age of the patients was 43.3 ± 13.80. 80 (53.3%) of the patients were male and 70 (46.7%) were females. Exploring more into UGIB causes the majority of patients were with esophageal varices 68 (45.3%) with male to female share was 2:1. The second most cause was esophagitis (n = 22, (14.67%)), the distribution of the cause was similar in male to female. Conclusion: We may conclude from our findings that the most common cause of UGIB is esophageal varices in our population.

关键词： Upper Gastrointestinal Endoscopy Esophageal Varices Upper Gastrointestinal Bleeding Peptic Ulcer

Mental Health Care in Saudi Arabia: Past, Present and Future

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Open Journal of Psychiatry 2014年第2期4卷 113-130页

作者： Harold G. Koenig Faten Al Zaben Mohammad Gamal Sehlo Doaa Ahmed Khalifa Mahmoud Shaheen Al Ahwal naseem Akhtar Qureshi Abdulhameed Abdullah Al-Habeeb Duke University Medical Center Durham USA King Abdulaziz University Jeddah KSA Ministry of Health Riyadh KSA

We review the past, present and future state of mental health care in the Kingdom of Saudi Arabia (KSA). The past is reviewed prior to the modern era, discussing early explanations and treatments for mental health illness up through the establishment of the first mental hospital in the 1950s, tracking advances in mental health care over the past 60 years. The present is explored in terms of the current need for mental health care based on the prevalence of mental health problems in KSA. We also discuss the role of the family in caring for the needs of the mentally ill today. Finally, we look forward into the future, discuss the current education system that will produce the next generation of mental health professionals, examine areas of mental health care that need improvement, and provide a research agenda to guide the continued development of the mental health care system in KSA. Our goal is to present a blue print for the development of a state-of-the-art mental health that may serve as a model for other countries in the Middle East, while taking into account the political, cultural and religious factors that are unique to this region of the world.

关键词： Mental Health Care Saudi Arabia Mental Health System Psychiatry Psychiatric Education Middle East Research

高负荷轴流压气机内以氦-氙混合气为工作介质的评估（英文）

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风机技术 2019年第2期61卷 10-15,I0006页

作者： Adil Malik Qun Zheng Hamza Fawzy naseem Ahmed Salman A.Ahmed College of Power and Energy Engineering Harbin Engineering University

本文评价了分子量为15g/mole 的氦-氙双项混合气体作为流动工质在核电厂轴流压气机的应用。由于纯氦具有普遍的传输特性,在很多情况下很难被压缩,因此是一种最佳的冷却剂。同时,纯氦工质在高温气冷堆(HTGR)的应用引起了涡轮机械的尺寸... 详细信息

本文评价了分子量为15g/mole 的氦-氙双项混合气体作为流动工质在核电厂轴流压气机的应用。由于纯氦具有普遍的传输特性,在很多情况下很难被压缩,因此是一种最佳的冷却剂。同时,纯氦工质在高温气冷堆(HTGR)的应用引起了涡轮机械的尺寸更大、质量越来越大、成本更高及叶轮机械的动力问题。为此,本文设计了一台高负荷氦氙压气机,并对其性能进行了分析。结果显示,只有18%的氦气压气机级需要在高负荷氦气-氙气压气机中将气体压缩至所需压力。通过设计分析,工作在闭式布雷顿循环(CBC)中高温气冷堆(HTGR)压气机,可由16 级减少到2 级。因此,在高温气冷堆电厂的涡轮压压气中,氦氙比纯氦更有优势。

关键词：轴流压气机混合气体氦工质高负荷氙气工作介质高温气冷堆闭式布雷顿循环

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镁铝合金氢化物的催化共水解制氢

镁铝合金氢化物的催化共水解制氢

肥大细胞在哮喘发生发展中的作用机制及中医药调控作用

第十四届中国包头·稀土产业论坛、中国稀土学会2022学术年会

作者：钟浩 Kashif naseem 欧阳柳章朱敏华南理工大学材料科学与工程学院广东省先进储能材料重点实验室

氢气的储存是氢能规模化应用中亟待解决的关键技术,目前水解制氢等不可逆固态储氢方法有望打破储氢技术的瓶颈。但是,常用于水解制氢的铝、氢化镁等材料,正面临着水解副产物阻隔水解反应所带来的水解动力学方面的问题[1]。因此,本工作以... 详细信息

氢气的储存是氢能规模化应用中亟待解决的关键技术,目前水解制氢等不可逆固态储氢方法有望打破储氢技术的瓶颈。但是,常用于水解制氢的铝、氢化镁等材料,正面临着水解副产物阻隔水解反应所带来的水解动力学方面的问题[1]。因此,本工作以AlMg为原料,通过氢化和球磨制备了Al和MgH紧密结合的水解制氢材料（MHA-2%NaOH）,并测试了其水解放氢性能。结果表明,在NaOH溶液中,MHA-2%NaOH可在328K、60min内放出1488mL/g的氢气,氢气的转化率达97%,这主要归功于Al和MgH在NaOH中共水解产生了蓬松的MgAl（OH）,该副产物并未有阻碍后续水解反应传质。但强碱NaOH对容器的腐蚀仍是一大问题,故进一步以AlMg为原料经氢化和球磨制备了MHA-1.5wt%Mo-3.5wt%BO水解材料。水解测试结果表明,在1M的AlCl溶液中,该材料可在室温、50min内放出1420mL/g的氢气,氢气转化率高达98%,其中Mo、BO的催化作用和共水解副产物MgAlO的生成,均对Al和MgH水解动力学性能的改善起关键作用。

关键词：镁铝合金氢化物共水解制氢

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世界中医药 2024年第14期19卷 2203-2211页

作者：刘珈含袁星星吕健安妮玛·纳西姆杨炳友黑龙江中医药大学哈尔滨150040 黑龙江省中医药科学院哈尔滨150036 哈尔滨医科大学附属第一医院哈尔滨150007 费萨拉巴德农业大学费萨拉巴德38000

哮喘在中医学中属于哮病、喘症的范畴,是以气道平滑肌收缩、免疫细胞浸润和气道重塑等为特征的气道炎症疾病。肥大细胞为非特异性免疫细胞,在哮喘的形成和发展中扮演关键角色。中医药对哮喘的防治具有独特优势,但具体机制尚不明确。通... 详细信息

哮喘在中医学中属于哮病、喘症的范畴,是以气道平滑肌收缩、免疫细胞浸润和气道重塑等为特征的气道炎症疾病。肥大细胞为非特异性免疫细胞,在哮喘的形成和发展中扮演关键角色。中医药对哮喘的防治具有独特优势,但具体机制尚不明确。通过对相关研究综述后发现,肥大细胞活化后释放的组胺、蛋白酶、细胞因子等介质在哮喘气道损伤及重塑的病理过程中起重要作用。此外,中药复方制剂、单味中药及其活性成分、中成药及中医外治法等中医药方法可通过调节肥大细胞活化,抑制多种炎症介质和细胞因子的表达,进而发挥对哮喘的治疗作用。

关键词：支气管哮喘肥大细胞中医药气道慢性炎症反应气道损伤气道重塑免疫细胞生物活性介质

离体及温室培养的Artemisia amygdalina的自由基清除功能(英文)

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中国天然药物 2013年第4期11卷 377-384页

作者： R.Rasool B.A.Ganai S.Akbar A.N.Kamili Department of Biochemistry University of KashmirHazratbalSrinagar 190006Jammu and KashmirIndia Regional Research Institute of Unani Medicine Naseem baghSrinagar 190006Jammu and KashmirIndia Plant Tissue Culture Laboratory Centre of Research for DevelopmentUniversity of KashmirHazratbalSrinagar 190006Jammu and KashmirIndia

AIM:Artemisia amygdalina Decne.(Asteraceae) is a critically endangered and endemic herb of Kashmir Himalayan sub-alpine region and *** research throughout the world has evidence to support the tremendous medicinal utility of the genus *** natural resources of medicinal plants are being reduced day by *** study provides the alternative way for medicinal resource utilization and conservation of ***:In vitro-raised plants and greenhouse acclimatized plants were obtained by culturing wild explants on Murashige and Skoog's *** extracts were obtained and subjected to different antioxidant assays:DPPH assay,riboflavin photo-oxidation assay,deoxy ribose assay,ferric thiocyanate assay,thiobarbituric acid assay,post mitochondrial supernatant assay and DNA damage on agarose ***:In vitro grown plants,as well as those acclimatized in the greenhouse reveals antioxidant activity against hydroxyl,superoxide,and lipid peroxyl ***:This preliminary study revealed the free radical scavenging potential of tissue culture-raised plant extracts of ***.

关键词：实验药理学药理病理作用天然药物