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Early Childho.d Develo.ment.(0 - 6 Years o.d) fro. Healt.y t.0}Pat.o.o.ic: A Review o. t.e Lit.rat.re

o.en Jo.rnal o. Medical Psycho.o.y 2020年第3期9卷 100-122页

作者： Chkirat. Meriem Mammad Khao.la Cht.bo. Ghizlane Mdaghri Alao.i Asmaa ahami o. t. ahmed Clinical Neuro.cience and Applied Nut.it.o. Unit Department of Biology Faculty of Sciences Kenitra Morocco Pediat.ic Service 2 Children’s Hospital University Hospital Center (UHC) Ibn Sina Rabat Morocco Research t.am in Co.genit.l Ano.alies Faculty of Medicine and Pharmacy Mohammed V University Rabat Morocco

Early childho.d develo.ment.invo.ves an appro.riat. glo.al int.rvent.o. co.cerning t.e different.areas o. develo.ment.such as: physical, co.nit.ve, language and so.io.emo.io.al [1]. Especially during t.e first.six ye... 详细信息

t.le="t.xt.align:just.fy;"> Early childho.d develo.ment.invo.ves an appro.riat. glo.al int.rvent.o. co.cerning t.e different.areas o. develo.ment.such as: physical, co.nit.ve, language and so.io.emo.io.al [1]. Especially during the first six years of life in an adequate environment rich in exchange and interaction. We will present in this article a review of the literature concerning normal early childhood development, focus firstly in normal development’s steps, the importance of first experiences and first aid with a stable and caring attachment figure. second, we will describe the various developmental disorders, occurring during this age group which extends from birth to 6 years and based on the DSM5 classification, namely that developmental delay may concern only one aspect of development (e.g. language delay or motor delay specifically) or concern the different aspects of development (overall development delay). The dynamics of development is also important to clarify because schematically we contrast the pathologies fixed to progressive pathologies (where we find the concepts of stagnation or regression in the development of the child). We will discuss in the third chapter, the interest of early detection as well as the multiple clinical and psychometric diagnostic tools, which aim to detect any delay or disorder in order to initiate appropriate care and minimize the long-term consequences.

关键词： Early Childho.d No.mal Develo.ment Develo.ment.l Diso.der Early Screening Remediat.o.

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Impact. o. mult.ple demand-side management.st.at.gies o. micro.rids planning:a lit.rat.re survey

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Clean Energy 2024年第1期8卷 36-54页

作者： Rasha Elazab ahmed t.Abdelnaby A.A.Ali Elect.ical Po.er and Machines Depart.ent Faculty of Engineering at Helwan UniversityCairoEgypt

Demand-side management.DSM)schemes play a crucial ro.e in managing renewable energy generat.o. and lo.d fluct.at.o.s by ut.-lizing demand-respo.se pro.rammes(DRPs).t.is paper aims t.0}pro.ide a det.iled o.erview o. DRPs t.at.help micro.rid o.erat.0}s t.0}keep co.t. and reliabilit. wit.in accept.ble ***,t.is review paper pro.ides a det.iled eco.o.ic lo.d mo.el fo. DRPs based o. init.al lo.d,demand-respo.se(DR)incent.ve,DR penalt. and elast.cit. *** art.cle also.aims t.0}guide researchers in ident.fying research gaps in DSM applicat.o.s in micro.rids by co.paring vario.s DSM schemes fro. different.co.nt.ies and regio.s in t.rms o. DSM st.at.gies,o.ject.ve funct.o.s and o.t.mizat.o. ***,t.is st.dy analyses t.e impact.o. DRPs o. micro.rid co.figurat.o. fro. t.e perspect.ve o. ut.lit.es and cust.0}ers,co.sidering t.chnical and eco.o.ic perfo.mance *** a result.it.can be co.cluded t.at.no.e o. t.e st.died cases pro.ides mo.els o. guidelines fo. cho.sing appro.riat. DSM schemes t.at.co.sider different.co.sumer int.rest. o. lo.d-t.pe ***,a few researchers have addressed t.e feat.res o. a mo.ern price-based DR st.at.gy,renewable generat.o.-based dynamic pricing DR,which o.fers higher cust.0}er sat.sfact.o. t.an t.adit.o.al DRPs.

关键词： demand-side management o.t.mal sizing demand-respo.se st.at.gies renewable generat.o.-based dynamic pricing

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Engineering nano.edicines fo. immuno.enic eradicat.o. o. cancer cells:Recent.t.ends and synergist.c appro.ches

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Act. Pharmaceut.ca Sinica B 2024年第6期14卷 2475-2504页

作者： ahmed o.Elzo.hby o.ar Samir Hagar E.Emam ahmed So.iman Riham M.Abdelgalil Yo.na M.Elmo.shedy Kadria A.Elkho.airy Mahmo.d L.Nasr Divisio. o. Engineering in Medicine and Divisio. o. Renal Medicine Department of MedicineBrigham and Women's HospitalHarvard Medical SchoolBoston 02115MAUSA Cancer Nano.echno.o.y Research Labo.at.0}y(CNRL) Faculty of PharmacyAlexandria UniversityAlexandria 21521Egypt

Resist.nce t.0}cancer immuno.herapy is mainly at.ribut.d t.0}po.r t.mo. immuno.enicit. as well as t.e immuno.uppressive t.mo. micro.nviro.ment.t.E)leading t.0}failure o. immune *** t.erapeut.c st.at.gies including chemo.herapy,radio.herapy,pho.o.ynamic,pho.o.hermal,magnet.c,chemo.ynamic,so.o.ynamic and o.co.yt.c t.erapy,have been develo.ed t.0}induce immuno.enic cell deat.(ICD)o. cancer cells and t.ereby elicit.immuno.enicit. and bo.st.t.e ant.t.mo. immune ***,many challenges hamper t.e clinical applicat.o. o. ICD inducers result.ng in mo.est.immuno.enic ***,we o.t.ine t.e current.st.t. o. using nano.edicines fo. bo.st.ng ICD o. cancer ***,synergist.c appro.ches used in co.binat.o. wit. ICD inducing nano.edicines fo. remo.eling t.e t.E via t.rget.ng immune checkpo.nt.,phago.yt.0}is,macro.hage po.arizat.o.,t.mo. hypo.ia,aut.0}hagy and st.o.al mo.ulat.o. t.0}enhance immuno.enicit. o. dying cancer cells were *** furt.er highlight.t.e emerging t.ends o. using nano.at.rials fo. t.iggering amplified ICD-mediat.d ant.t.mo. immune *** ret.culum lo.alized ICD,fo.used ult.aso.nd hypert.ermia,cell membrane camo.flaged nano.edicines,amplified react.ve o.ygen species(Ro.)generat.o.,met.llo.immuno.herapy,io. mo.ulat.0}s and engineered bact.ria are amo.g t.e mo.t.inno.at.ve *** challenges,merit. and demerit. o. ICD inducer nano.edicines were also.discussed wit. shedding light.o. t.e fut.re ro.e o. t.is t.chno.o.y in impro.ing t.e o.t.o.es o. cancer immuno.herapy.

关键词： Immuno.enic cell deat. Immuno.enic eradicat.o. Nano.edicines Drug delivery Cancer immuno.herapy Ant.t.mo. immunit. t.cells t.mo. asso.iat.d ant.gens Synergist.c immune respo.se

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t.e impact.o. chemo.herapy-naïve o.en radical cyst.ct.0}y delay and perio.erat.ve t.ansfusio. o. t.e recurrence-free survival: A perio.erat.ve paramet.rs-based no.o.ram

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Asian Jo.rnal o. Uro.o.y 2024年第2期11卷 294-303页

作者： ahmed M.Harraz ahmed Elkart. Mo.amed H.Zahran ahmed Mo.bah At.llah A.Shaaban Hassan Abo.-Enein Uro.o.y and Nephro.o.y Cent.r Mansoura UniversityEgypt

o.ject.ve: t.0}develo. and int.rnally validat. a no.o.ram t.0}predict.recurrence-free survival (RFS) including t.e t.me t.0}radical cyst.ct.0}y (RC) and perio.erat.ve blo.d t.ansfusio. (PBt. as po.ent.al ***: Pat.ent. who.underwent.o.en RC and ileal co.duit.bet.een January 1996 t.0}December 2016 were split.int.0}develo.ing (n=948) and validat.ng (n=237) co.o.t.. t.e t.me t.0}radical cyst.ct.0}y (t.C) was defined as t.e int.rval bet.een t.e o.set.o. sympt.0}s and RC. t.e regressio. co.fficient. o. t.e independent.predict.0}s o.t.ined by Co. regressio. were used t.0}co.st.uct.t.e no.o.ram. Discriminat.o., validat.o., and clinical usefulness in t.e validat.o. co.o.t.were assessed by t.e area under t.e curve, t.e calibrat.o. plo., and decisio. curve ***: In t.e develo.ing dat.set. t.e 1-, 5-, and 10-year RFS were 83.0%, 47.2%, and 44.4%, respect.vely. o. mult.variat. analysis, independent.predict.0}s were t.C (hazards rat.o.[HR] 1.07, 95% co.fidence int.rval [CI] 1.05-1.08, pt.(o.e unit. HR 1.40, 95% CI 1.03-1.90, p=0.03;t.o.o. mo.e unit.: HR 1.72, 95% CI 1.29-2.29, pt.ral hydro.ephro.is (HR 1.54, 95% CI 1.21-1.97, po.s cell carcino.a (HR 0.60, 95% CI 0.45-0.81, p=0.001), pt.-t. (HR 1.77, 95% CI 1.41-2.22, po.e st.t.s (HR 1.53, 95% CI 1.21-1.95, po.ascular invasio. (HR 1.28, 95% CI 1.01-1.62, p=0.044). t.e areas under t.e curve in t.e validat.o. dat.set.were 79.3%, 69.6%, and 76.2%, fo. 1-, 5-, and 10-year RFS, respect.vely. Calibrat.o. plo.s sho.ed co.siderable co.respo.dence bet.een predict.d and act.al survival pro.abilit.es. t.e decisio. curve analysis revealed a bet.er net.benefit.o. t.e ***: A no.o.ram wit. go.d discriminat.o., validat.o., and clinical ut.lit. was co.st.uct.d ut.lizing t.C and PBt.in addit.o. t.0}st.ndard pat.o.o.ical crit.ria.

关键词： Radicalcyst.ct.0}y Blo.d t.ansfusio. t.me t.0}radical cyst.ct.0}y Survival No.o.ram

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Rhizo.ium Ino.ulat.o. and Micro.ut.ient.Addit.o. Influence t.e Gro.t.,Yield,Qualit. and Nut.ient.Upt.ke o. Garden Peas(Pisum sat.vum L.)

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Phyt.0}-Int.rnat.o.al Jo.rnal o. Experiment.l Bo.any 2024年第5期93卷 901-922页

作者： MdAbdul Quddus MdAt.ur Rahman Razu ahmed Mo.ammad Eyakub Ali Kho.an Kumer Sarker MdAlamgir Siddiky Mo.ibur Rahman Lamya ahmed Alkeridis Samy Sayed ahmed Gaber Akbar Ho.sain Ho.t.cult.re Research Cent.e Bangladesh Agricultural Research InstituteGazipur1701Bangladesh So.l Science Divisio. Bangladesh Agricultural Research InstituteGazipur1701Bangladesh Irrigat.o. and Wat.r Management.Divisio. Bangladesh Agricultural Research InstituteGazipur1701Bangladesh Regio.al Agricult.ral Research St.t.o. Bangladesh Agricultural Research InstituteCumilla3500Bangladesh Depart.ent.o. Bio.o.y College of SciencePrincess Nourah Bint Abdulrahman UniversityP.O.Box 84428Riyadh11671Saudi Arabia Depart.ent.o. Science and t.chno.o.y University College‑RanyahTaif UniversityP.O.Box 11099Taif21944Saudi Arabia Depart.ent.o. Eco.o.ic Ent.0}o.o.y and Pest.cides Faculty of AgricultureCairo UniversityGiza12613Egypt Depart.ent.o. Genet.cs Faculty of AgricultureCairo UniversityGiza12613Egypt Depart.ent.o. Bio.o.y College of ScienceTaif UniversityTaif21944Saudi Arabia Divisio. o. So.l Science Bangladesh Wheat and Maize Research InstituteDinajpur5200Bangladesh

Garden pea pro.uct.vit. and qualit.es are hampered in zinc(Zn),bo.o.(B),and mo.ybdenum(Mo.deficient.***,t.e co.binat.o. o. micro.ut.ient.(i.e.,Zn,B,and Mo.and rhizo.ium is necessary t.0}increase t.e pro.uct.vit. and qualit. o. garden peas,since t.is management.fo. garden peas is neglect.d in ***,t.e present.st.dy was made t.0}assess t.e effect.veness o. rhizo.ium ino.ulant.singly o. in co.binat.o. wit. t.e micro.ut.ient.(i.e.,Zn,B,and Mo.o. gro.t.,yield,nut.ient.upt.ke,and qualit. o. garden *** were:t.(1)=Co.t.o.,t.(2)=Rhizo.ium ino.ulat.o. at.50 g/kg seed,t.(3)=t.(2)+Zn_(3)Mo.,t.(4)=t.(2)+B_(2)Mo.,t.(5)=t.(2)+Zn_(3)B_(2),t.(6)=t.(2)+Zn_(3)B_(2)Mo. and t.(7)=Zn_(3)B_(2)*** t.eat.ent. were arranged in a rando.ized co.plet. blo.k design and repeat.d all t.eat.ent. in t.ree *** applicat.o. o. 3 kg Zn,2 kg B,and 1 kg Mo.ha^(−1)wit. ino.ulat.o. o. Rhizo.ium at.50 g kg^(−1)seed(t.(6))facilit.t.d t.0}increase o. 44.8%in t.e green po. and 29.7%seed yield o.er *** same t.eat.ent.co.t.ibut.d t.0}at.aining t.e maximum no.ulat.o.(25.3 plant.(−1)),Vit.min C(43.5 mg 100 g^(−1)),pro.ein co.t.nt.22.2%),and nut.ient.upt.ke as well as accumulat.o. in garden *** all t.eat.ent.co.binat.o.s,t.eat.ent.t.(6)was fo.nd superio. t.0}o.hers based o. micro.ial act.vit.es,so.l fert.lit.,and *** result. o. t.e st.dy fo.nd t.at.t.e applicat.o. o. 3 kg Zn,2 kg B,and 1 kg Mo.ha^(−1)in co.binat.o. wit. Rhizo.ium ino.ulat.o.(50 g kg^(−1)seed)can impro.e t.e yield and qualit. o. garden *** result. o. t.e st.dy have t.e po.ent.al fo. t.e areas,where t.ere is no.use o. Rhizo.ium ino.ulant.o. Zn,B,and Mo.fert.lizer fo. cult.vat.o. o. garden pea.

关键词： No.ulat.o. nut.ient.co.t.nt Pisum sat.vum L. pro.it.bilit. rhizo.ium Zn B Mo

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Remo.eling t.mo. Immune Micro.nviro.ment.by Using Po.ymer-Lipid-Manganese Dio.ide Nano.art.cles wit. Radiat.o. t.erapy t.0}Bo.st.Immune Respo.se o. Cast.at.o.-Resist.nt.Pro.t.t. Cancer

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Research 2024年第3期2023卷 83-96页

作者： Abdulmo.t.leb E.Zet.ini Ho.in Lip Azhar Z.Abbasi Ibrahim Alradwan t.ksim ahmed Chunsheng He Jeffrey t.Henderso. Andrew M.Raut. Xiao.Yu Wu Advanced Pharmaceut.cs and Drug Delivery Labo.at.0}y Leslie Dan Faculty of PharmacyUniversity of TorontoM5S 3M2TorontoONCanada. Depart.ent. o. Medical Bio.hysics and Radiat.o. o.co.o.y University of TorontoM5G 1L7TorontoONCanada.

Despit. subst.nt.al pro.ress in t.e t.eat.ent.o. cast.at.o.-resist.nt.pro.t.t. cancer (CRPC), including radiat.o. t.erapy and immuno.herapy alo.e o. in co.binat.o., t.e respo.se t.0}t.eat.ent.remains po.r due t.0}t.e hypo.ic and immuno.uppressive nat.re o. t.e t.mo. micro.nviro.ment. Herein, we explo.t.d t.e bio.eact.vit. o. no.el po.ymer–lipid manganese dio.ide nano.art.cles (PLMDs) t.0}remo.el t.e t.mo. immune micro.nviro.ment.(t.ME) by increasing t.e lo.al o.ygen levels and ext.acellular pH and enhancing radiat.o.-induced immuno.enic cell deat.. t.is st.dy demo.st.at.d t.at.PLMD t.eat.ent.sensit.zed hypo.ic human and murine CRPC cells t.0}radiat.o., significant.y increasing radiat.o.-induced DNA do.ble-st.and breaks and ult.mat.ly cell deat., which enhanced t.e secret.o. o. damage-asso.iat.d mo.ecular pat.erns, at.ribut.ble t.0}t.e induct.o. o. aut.0}hagy and endo.lasmic ret.culum st.ess. Reo.ygenat.o. via PLMDs also.po.arized hypo.ic murine RAW264.7 macro.hages t.0}ard t.e M1 pheno.ype, enhancing t.mo. necro.is fact.0} alpha release, and t.us reducing t.e viabilit. o. murine CRPC t.AMP-C2 cells. In a syngeneic t.AMP-C2 t.mo. mo.el, int.aveno.s inject.o. o. PLMDs suppressed, while radiat.o. alo.e enhanced recruit.ent.o. regulat.0}y t.cells and myelo.d-derived suppresso. cells. Pret.eat.ent.wit. PLMDs fo.lo.ed by radiat.o. do.n-regulat.d pro.rammed deat.-ligand 1 and pro.o.ed t.e infilt.at.o. o. ant.t.mo. CD8+ t.cells and M1 macro.hages t.0}t.mo. sit.s. t.ken t.0}et.er, t.ME mo.ulat.o. by PLMDs plus radiat.o. pro.o.ndly delayed t.mo. gro.t. and pro.o.ged median survival co.pared wit. radiat.o. alo.e. t.ese result. suggest.t.at.PLMDs plus radiat.o. is a pro.ising t.eat.ent.mo.alit. fo. impro.ing t.erapeut.c efficacy in radio.esist.nt.and immuno.uppressive so.id t.mo.s.

关键词： RAW264.7 alo.e t.eat.ent

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Effect.veness o. ext.rnal prest.essing in enhancing t.e no.-duct.le hanger failure mechanism in reinfo.ced co.cret. invert.d t.beams

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Fro.t.ers o. St.uct.ral and Civil Engineering 2024年第7期18卷 1050-1065页

作者： ahmed M.At.A Reda N.BEHIRY Mo.ammed I.HARAZ St.uct.ral Engineering Depart.ent Faculty of EngineeringTanta UniversityTanta 33511Egypt Nile Higher Inst.t.t. fo. Engineering and t.chno.o.y Mansoura 11001Egypt

Recent.y,invert.d t.beams have been used in reinfo.ced co.cret.(RC)bridges t.0}suppo.t.t.ansverse precast.*** t.beams,co.t.ary t.0}pract.ce wit. co.vent.o.al beams,are lo.ded o. t.e flanges upper *** lo.ding co.figurat.o. causes hanger failure due t.0}t.e generat.o. o. vert.cal t.nsile st.esses near t.e bo.t.0} o. t.e *** key purpo.e o. t.is st.dy is t.0}invest.gat. t.e efficiency o. vert.cal ext.rnal prest.essing st.inless-st.el bars in mit.gat.ng no.-duct.le hanger failure in reinfo.ced co.cret. invert.d *** experiment.l st.dy o. six invert.d-t.beams,including t.o.un-st.engt.ened specimens,was carried *** st.dy sho.ed t.at.t.e value o. t.e prest.essing level had a co.siderable impact.o. t.e perfo.mance o. hanger mechanism in relat.o. t.0}crack pat.ern,ult.mat. lo.ds,cracking behavio.,lo.d-deflect.o.,st.ains,and *** experiment.l result. indicat.d t.at.t.e suggest.d met.o. fo. st.engt.ening invert.d t.beams had efficacy in reducing t.e serio.sness o. t.e no.-duct.le hanger failure and result.d in a st.engt. increase o. up t.0}53% when co.pared t.0}t.at.o. t.e un-st.engt.ened ***,t.o.analyt.cal mo.els fo. est.mat.ng t.e hanger capacit. and t.e average crack widt. o. t.e st.engt.ened RC invert.d t.beams were *** mo.els t.at.were pro.o.ed exhibit.d a high degree o. agreement.wit. t.e experiment.l result..

关键词： RC bridges invert.d t.beams st.engt.ening hanger failure ext.rnal prest.essing

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Cerebral veno.s sinus t.ro.bo.is:changing t.ends in t.e incidence,age and gender(findings fro. t.e CMC Vello.e CVt.regist.y)

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St.o.e & Vascular Neuro.o.y 2024年第3期9卷 252-257页

作者： Angel Miraclin t.Jo.n Davis Prasad Geo.ge Abraham Ninan Mahasampat. Go.ri Deept. Bal At.f Iqbal ahmed Shaikh Ro.it.N Benjamin Appaswamy t.irumal Prabhakar Ajit. Sivadasan Vivek Mat.ew Sanjit. Aaro. Depart.ent.o. Neuro.o.ical Sciences Christian Medical CollegeVelloreTamil NaduIndia Depart.ent.o. Bio.t.t.st.cs Christian Medical CollegeVelloreTamil NaduIndia

Backgro.nd Mult.ple cerebral veno.s sinus t.ro.bo.is(CVt.regist.ies fro. vario.s geo.raphical regio.s indicat. t.at.female gender,t.e use o. co.t.acept.ve pills,pregnancy and puerperium are impo.t.nt.risk *** t.is st.dy,we repo.t.t.e changes in t.e epidemio.o.y o. pat.ent. wit. CVt.managed o.er t.e past.26 *** t.e CMC Vello.e CVt.regist.y is a pro.pect.vely maint.ined dat.base at.t.e Christ.an Medical Co.lege,Vello.e since January *** so.t.are was used t.0}analyse t.e dat. and assess t.e changes in t.e incidence,age and gender dist.ibut.o. o.er t.e previo.s 26 *** Amo.g 1701 pat.ent. t.eat.d during t.e st.dy perio.,908(53%)were wo.en and 793(47%)were *** mean incidence o. CVt.was 49 per 100000 admissio.s befo.e 2010,which increased t.0}96 per 100000 aft.r *** gender had a higher o.ds o. develo.ing CVt.o.–2.07(CI 1.68 t.0}2.55,pt.is co.ld be at.ribut.d t.0}t.e declining incidence o. po.t.art.m CVt.aft.r 2010 co.pared wit. t.e decade befo.e 2010(50%vs 20%).t.e mean age at.present.t.o. had increased fro. 24.5 t.0}33.2 years in t.e last.*** t.ere was a clear change in t.e gender pat.ern fro. being a co.dit.o. wit. female prepo.derance,t.0}o.e where equal o. mo.e men are being *** incidence o. po.t.art.m CVt.cases co.ld be t.e driving *** increase in t.e o.erall incidence o. CVt.cases was no.ed,pro.ably due t.0}a higher index o. clinical suspicio. and bet.er diagno.t.c imaging mo.alit.es.

关键词： CVt driving maint.ined

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Enhancing Dat. Fo.warding Efficiency in SIo. wit. Mult.dimensio.al So.ial Relat.o.s

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Co.put.rs, Mat.rials & Co.t.nua 2024年第1期78卷 1095-1113页

作者： Fang Xu So.ghao.Jiang Yi Ma Manzo.r ahmed Zenggang Xio.g Yuanlin Lyu Scho.l o. Co.put.r and Info.mat.o. Science Hubei Engineering UniversityXiaogan432000China Scho.l o. Co.put.r Science and Info.mat.o. Engineering Hubei UniversityWuhan430062China Art.ficial Int.lligence Indust.ial t.chno.o.y Research Inst.t.t. Hubei Engineering UniversityXiaogan432000China

Effect.ve dat. co.municat.o. is a crucial aspect.o. t.e So.ial Int.rnet.o. t.ings(SIo.)and co.t.nues t.0}be a significant.research *** paper pro.o.es a dat. fo.warding algo.it.m based o. Mult.dimensio.al So.ial Relat.o.s(MSRR)in SIo. t.0}so.ve t.is *** pro.o.ed algo.it.m separat.s message fo.warding int.0}int.a-and cro.s-co.munit. fo.warding by analyzing int.rest.t.ait. and so.ial co.nect.o.s amo.g *** new met.ics are defined:t.e int.nsit. o. no.e so.ial relat.o.ships,no.e act.vit.,and co.munit. *** t.e co.munit.,messages are sent.by det.rmining which no.e is mo.t.similar t.0}t.e sender by weighing t.e st.engt. o. so.ial co.nect.o.s and no.e *** a no.e perfo.ms cro.s-co.munit. fo.warding,t.e message is fo.warded t.0}t.e mo.t.reaso.able relay co.munit. by measuring t.e no.e act.vit. and t.e co.nect.o. bet.een *** pro.o.ed algo.it.m was co.pared t.0}t.ree exist.ng ro.t.ng algo.it.ms in simulat.o. *** indicat. t.at.t.e pro.o.ed algo.it.msubst.nt.ally impro.es message delivery efficiency while lessening net.o.k o.erhead and enhancing co.nect.vit. and co.rdinat.o. in t.e SIo. co.t.xt.

关键词： SIo. dat. fo.warding so.ial at.ribut.s so.ial relat.o.s co.munit.

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Gast.o.so.hageal reflux aft.r per-o.al endo.co.ic myo.o.y:Management.lit.rat.re

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Wo.ld Jo.rnal o. Gast.o.nt.ro.o.y 2024年第23期30卷 2947-2953页

作者： ahmed t.wheed Ibrahim Halil Bahcecio.lu Mehmet.Yalniz Mo.amed El-Kassas Depart.ent.o. Endemic Medicine Faculty of MedicineHelwan UniversityCairo 11795Egypt Depart.ent.o. Gast.o.nt.ro.o.y Faculty of MedicineFirat UniversityElazig 23119Türkiye Liver Disease Research Cent.r College of MedicineKing Saud UniversityRiyadh 7805Saudi Arabia

In t.is edit.0}ial,we respo.d t.0}a review art.cle by Nabi et.al,in which t.e aut.o.s discussed gast.o.so.hageal reflux(GER)fo.lo.ing pero.al endo.co.ic myo.o.y(Po.M).Po.M is present.y t.e primary t.erapeut.c o.t.o. fo. achalasia,which is bo.h safe and effect.ve.A few adverse effect. were do.ument.d aft.r Po.M,including *** diagno.t.c crit.ria were no. clear eno.gh because appro.imat.ly 60%o. pat.ent. have a lo.g acid expo.ure t.me,while o.ly 10%experience reflux *** predict.0}s o. high disease incidence have been ident.fied,including o.d age,female sex,o.esit.,and a baseline lo.er eso.hageal sphinct.r pressure o. less t.an 45 *** t.chnical st.ps during t.e pro.edure,such as a lengt.y o. full-t.ickness myo.o.y,may furt.er enhance t.e *** pump inhibit.0}s are current.y t.e first.line o. *** vo.ces are increasingly advo.at.ng fo. t.e ro.t.ne co.bining o. Po.M wit. an endo.co.ic fundo.licat.o. met.o.,such as pero.al endo.co.ic fundo.licat.o. o. t.anso.al incisio.less ***,mo.e research is necessary t.0}det.rmine t.e safet. and effect.veness o. t.ese pro.edures in t.e lo.g t.rm fo. pat.ent. who.have undergo.e t.em.

关键词： Achalasia Per-o.al endo.co.ic myo.o.y Gast.o.so.hageal reflux disease t.anso.al incisio.less fundo.licat.o. Pero.al endo.co.ic fundo.licat.o.

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