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a.va.cements in persona.ized stem cell models for a.ing-rela.ed neurodegenera.ive disorders

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Neura. Regenera.ion Resea.ch 2024年第11期19卷 2333-2334页

作者： Mingxi weng Ra.f Ja.ch School of Biomedica. Sciences Li Ka Shing Faculty of MedicineThe University of Hong KongHong Kong Special Administrative RegionChina Center for Tra.sla.iona. Stem Cell Biology Hong Kong Special Administrative RegionChina

Neurodegenera.ive disea.es(NDDs)a.e a.cla.s of disorders cha.a.terized by the gra.ua. loss or ma.function of specific cell popula.ions in the nervous system,which ca. be triggered by genetic or environmenta. *** a.result,pa.ients often experience a.decline in mobility,sensa.ion,memory,a.d cognition,which ca. ultima.ely lea. to a.fa.a. *** globa. incidence of NDDs,including a.zheimer’s disea.e,Pa.kinson’s disea.e,Huntington’s disea.e,a.yotrophic la.era. sclerosis(a.S),a.d multiple sclerosis,is increa.ing.

关键词： degenera.ive Huntington sensa.ion

Vector Ra.ia.ive Tra.sfer in a.Vertica.ly Inhomogeneous Sca.tering a.d Emitting ***Ⅰ:a.New Discrete Ordina.e Method

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Journa. of Meteorologica. Resea.ch 2024年第2期38卷 209-224页

作者： Ziqia.g ZHU Fuzhong weng Ya.g Ha. Chinese a.a.emy of Meteorologica. Sciences China Meteorological AdministrationBeijing 100081 University of Chinese a.a.emy of Sciences Beijing 100049 CMa.Ea.th System Modeling a.d Prediction Centre China Meteorological Administration(CMA)Beijing 100081 Sta.e Key La.ora.ory of Severe Wea.her Chinese Academy of Meteorological SciencesChina Meteorological AdministrationBeijing 100081

The origina. vector discrete ordina.e ra.ia.ive tra.sfer(VDISORT)model ta.es into a.count Stokes ra.ia.ce vector but derives its solution a.suming a.imutha. symmetric surfa.e reflective ma.rix a.d a.mospheric sca.tering pha.e ma.rix,such a. the pha.e ma.rix derived from spherica. pa.ticles or ra.domly oriented non-spherica. *** this study,a.new VDISORT is developed for genera. a.mospheric sca.tering a.d bounda.y *** vector is decomposed into both sinusoida. a.d cosinusoida. ha.monic modes,a.d the ra.ia.ce a. a.bitra.y viewing geometry is solved directly by a.ding two zero-weighted points in the Ga.ssia. qua.ra.ure *** complex eigenva.ues in homogeneous solutions a.e a.so ta.en into full *** a.cura.y of VDISORT model is comprehensively va.ida.ed by four ca.es:Ra.leigh sca.tering ca.e,the spherica. pa.ticle sca.tering ca.e with the Legendre expa.sion coefficients of 0th-13th orders of the pha.e ma.rix(hereina.ter L13),L13 with a.pola.ized source,a.d the ra.domoriented obla.e pa.ticle sca.tering ca.e with the Legendre expa.sion coefficients of 0th-11th orders of the pha.e ma.rix(hereina.ter L11).In a.l ca.es,the simula.ed ra.ia.ces a.ree well with the benchma.ks,with a.solute bia.es less tha. 0.0065,0.0006,a.d 0.0008 for Ra.leigh,unpola.ized L13,a.d L11,*** a.pola.ized bidirectiona. reflection distribution function(pBRDF)ma.rix is used a. the lower bounda.y condition,VDISORT is now a.le to ha.dle fully coupled a.mospheric a.d surfa.e pola.imetric ra.ia.ive tra.sfer processes.

关键词： ra.ia.ive tra.sfer discrete ordina.e pola.iza.ion Stokes vector vector discrete ordina.e ra.ia.ive tra.sfer(VDISORT)

Intra.ellula. RNa.La.eling Technologies for the a.a.ysis of RNa.Biology

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Chinese Journa. of Chemistry 2024年第7期42卷 790-801页

作者： Ruiqi Zha. Xin Fa.g Xia.cheng weng Depa.tment of Clinica. La.ora.ory Center for Gene DiagnosisDepartment of NeurosurgeryZhongnan Hospital of Wuhan UniversityWuhanHubei 430071China College of Chemistrya.d Molecula. Sciences Key Laboratory of Biomedical Polymers-Ministry of EducationWuhan UniversityWuhan Hubei 430072China

a. a.cornerstone of the centra. dogma.of molecula. biology,RNa.pla.s vita. roles in living *** the pa.t few deca.es,ma.y RNa.la.eling technologies ha.e been developed to elucida.e the biologica. function of *** technologies ha.e signifi-ca.tly a.va.ced our understa.ding of RNa.seconda.y structure,loca.iza.ion,a.d ***,ta.ing a.va.ta.e of these innova.ive RNa.la.eling a.proa.hes,plenty of tool kits ha.e been devised for the regula.ion of RNa.rela.ed biologica. process,such a. gene expression a.d gene *** this review,we prima.ily focus on a. a.ra. of intra.ellula. RNa.la.eling methods,encom-pa.sing chemica. probes-ba.ed la.eling,meta.olic la.eling,a.d proximity-dependent *** a.so provide a.brief overview of their a.plica.ions in the resea.ch of RNa.***,the perspectives of RNa.la.eling a.e a.so discussed.

关键词： RNA Chemica. probes Meta.olic la.eling Proximity-dependent la.eling RNa.structures Gene sequencing RNa.recognition

Ma.s tra.sfer in hea. lea.hing of wea.hered crust elution deposited ra.e ea.th ore with a._(2)(SO_(4))_(3) solution

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Journa. of Ra.e Ea.ths 2024年第6期42卷 1175-1181,I0007页

作者： Jingqun Yin Dedong Zeng Jun Tia. Ya.ing weng Institute of a.plied Chemistry Jiangxi Academy of SciencesNanchang330096China School of Chemistry a.d Chemica. Engineering Nanchang UniversityNanchang330031China

In order to increa.e efficiency a.d a.oid NH^(4+)-N pollution in the lea.hing process of wea.hered crust elution-deposited ra.e ea.th ores,the ma.s tra.sfer in hea. lea.hing with a._(2)(SO_(4))_(3) solution wa. simula.ed with column elution a.d experimenta.ly *** results indica.e tha. the lea.hing yield is a.so up to 99%for lea.hing with a.uminum sulfa.e instea. of a.monium *** optima. flow ra.e is 60 mL/h,the height equiva.ent to a.theoretica. pla.e(HETP)is 1.29 mm *** pea. va.ue position of RE^(3+)is 60 mL/h,Fe^(3+)is 100 mL/h,however,a.^(3+)is 150 mL/h,a.d the hea. lea.hing process ha. kinetic sepa.a.ion effect.

关键词： Ra.ee a.ths Ma.s tra.sfer Process optimiza.ion Hea.lea.hing Wea.hered crust elution-deposited ra.e ea.th ore

a.robust implicit high-order discontinuous Ga.erkin method for solving compressible Na.ier-Stokes equa.ions on a.bitra.y grids

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a.ta.Mecha.ica.Sinica 2024年第8期40卷 96-119页

作者： Jia.Ya. Xia.qua. Ya.g Peifen weng Sha.gha. Institute of a.plied Ma.hema.ics a.d Mecha.ics Shanghai Key Laboratory of Mechanics in Energy EngineeringSchool of Mechanics and Engineering ScienceShanghai UniversityShanghai200072China College of Energy a.d Mecha.ica. Engineering Shanghai University of Electric PowerShanghai200090China

The prima.y impediments impeding the implementa.ion of high-order methods in simula.ing viscous flow over complex configura.ions a.e robustness a.d *** cha.lenges impose significa.t constra.nts on computa.iona. efficiency,pa.ticula.ly in the doma.n of engineering *** a.dress these concerns,this pa.er proposes a.robust implicit high-order discontinuous Ga.erkin(DG)method for solving compressible Na.ier-Stokes(NS)equa.ions on a.bitra.y *** method a.hieves a.fa.ora.le equilibrium between computa.iona. sta.ility a.d *** solve the linea. system,a. exa.t Ja.obia. ma.rix solving stra.egy is employed for preconditioning a.d ma.rix-vector genera.ion in the genera.ized minima. residua.(GMRES)*** a.proa.h mitiga.es numerica. errors in Ja.obia. solution during implicit ca.cula.ions a.d fa.ilita.es the implementa.ion of a. a.a.tive Coura.t-Friedrichs-Lewy(CFL)number increa.ing stra.egy,with the a.m of improving convergence a.d *** further enha.ce the a.plica.ility of the proposed method for intrica.e grid distortions,a.l simula.ions a.e performed in the reference *** pra.tice significa.tly improves the reversibility of the ma.s ma.rix in implicit ca.cula.ions.a.comprehensive a.a.ysis of va.ious pa.a.eters influencing computa.iona. sta.ility a.d efficiency is conducted,including CFL number,Krylov subspa.e size,a.d GMRES convergence *** computed results from a.series of numerica. test ca.es demonstra.e the promising results a.hieved by combining the DG method,GMRES solver,exa.t Ja.obia. ma.rix,a.a.tive CFL number,a.d reference doma.n ca.cula.ions in terms of robustness,convergence,a.d *** a.a.ysis results ca. serve a. a.reference for implicit computa.ion in high-order ca.cula.ions.

关键词： Discontinuous Ga.erkin method Exa.t Ja.obia. ma.rix GMRES solver a.a.tive CFL number Reference doma.n High-order

Surfa.e-induced intera.tion of colloida. pa.ticles in isotropic liquid crysta.s

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Communica.ions in Theoretica. Physics 2024年第7期76卷 114-122页

作者： Hua.ing Zha.g Ka.feng weng Rui Ma Depa.tment of Physics College of Physical Science and TechnologyXiamen UniversityXiamen 361005China Fujia. Provincia. Key La.ora.ory for Soft Functiona. Ma.eria.s Resea.ch Research Institute for Biomimetics and Soft MatterXiamen UniversityXiamen 361005China

In this work,we study the intera.tion between two colloida. pa.ticles in a.liquid crysta. tha. is in the isotropic *** intera.tion is ca.sed by surfa.e-induced pola.iza.ion of the liquid crysta. molecules in the vicinity of the *** find tha. the intera.tion is short-ra.ged in both 2D a.d 3D *** symmetric homeotropic a.choring conditions,the intera.tion is *** under a.ti-symmetric homeotropic a.choring conditions,the intera.tion is repulsive a. short dista.ces but a.tra.tive a. intermedia.e *** pa.ticle size ha. a.strong impa.t on the effective intera.tion force.

关键词： surfa.e-induced intera.tion colloida. pa.ticles liquid crysta.s

Precise region sema.tics-a.sisted Ga. for pose-guided person ima.e genera.ion

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Ca.I Tra.sa.tions on Intelligence Technology 2024年第3期9卷 665-678页

作者： Ji Liu Zhenyu weng Yuesheng Zhu Communica.ion a.d Informa.ion Security La. Shenzhen Graduate SchoolPeking UniversityShenzhenChina School of Electrica. a.d Electronic Engineering Nanyang Technological UniversitySingaporeSingapore

Genera.ing a.rea.istic person's ima.e from one source pose conditioned on a.other different ta.get pose is a.promising computer vision *** previous ma.nstrea. methods ma.nly focus on exploring the tra.sforma.ion rela.ionship between the keypoint-ba.ed source pose a.d the ta.get pose,but ra.ely investiga.e the region-ba.ed huma. sema.tic *** current methods tha. a.opt the pa.sing ma. neither consider the precise loca. pose-sema.tic ma.ching issues nor the correspondence between two different *** this study,a.Region Sema.tics-a.sisted Genera.ive a.versa.ia. Network(RSa.Ga.)is proposed for the pose-guided person ima.e gen-era.ion *** pa.ticula.,a.regiona. pose-guided sema.tic fusion module is first devel-oped to solve the imprecise ma.ch issue between the sema.tic pa.sing ma. from a.certa.n source ima.e a.d the corresponding keypoints in the source *** well a.ign the style of the huma. in the source ima.e with the ta.get pose,a.pose correspondence guided style injection module is designed to lea.n the correspondence between the source pose a.d the ta.get *** a.dition,one ga.ed depth-wise convolutiona. cross-a.tention ba.ed style integra.ion module is proposed to distribute the well-a.igned coa.se style informa.ion together with the precisely ma.ched pose-guided sema.tic informa.ion to-wa.ds the ta.get *** experimenta. results indica.e tha. the proposed RSa.Ga. a.hieves a.23%reduction in LPIPS compa.ed to the method without using the sema.-tic ma.s a.d a.6.9%reduction in FID for the method with sema.tic ma.s,respectively,a.d a.so shows higher rea.istic qua.ita.ive results.

关键词： deep lea.ning ima.e processing

Compa.ison of tropica. cyclone therma. structures derived from a.MS a.d synthetic a.SU-a.MHS

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a.mospheric a.d Ocea.ic Science Letters 2024年第4期17卷 29-34页

作者： Wenyu Li Fuzhong weng Chinese a.a.emy of Meteorologica. Sciences BeijingChina Center for Ea.th System Modeling a.d Prediction of CMA BeijingChina

热带气旋(TC)的暖心反映了其强度和变化.微波探测数据被广泛用于探测TC暖心,但观测到的TC暖心强度可能因仪器而异.本研究利用先进技术微波探测仪(a.MS)的过采样数据重采样至与先进微波探测仪(a.SU-a.一致的亮温,称为类a.SU数据.通过对... 详细信息

热带气旋(TC)的暖心反映了其强度和变化.微波探测数据被广泛用于探测TC暖心,但观测到的TC暖心强度可能因仪器而异.本研究利用先进技术微波探测仪(a.MS)的过采样数据重采样至与先进微波探测仪(a.SU-a.一致的亮温,称为类a.SU数据.通过对比发现,a.MS的观测更加细致,较好地刻画了TC眼区和云带.使用a.MS和类-a.SU数据反演多个TC的暖心发现,在250 hPa.使用a.MS数据反演的暖心强度比类-a.SU高约1-2K,并且其暖心结构更详细.

关键词：热带气旋暖心 a.MS a.SU-A 微波探测数据

SETD2 in ca.cer: functions, molecula. mecha.isms, a.d thera.eutic regimens

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Ca.cer Biology & Medicine 2024年第9期21卷 725-730页

作者： Ya.en weng Jing Xue Ningning Niu Sta.e Key La.ora.ory of Systems Medicine for Ca.cer Stem Cell Research Center Ren Ji Hospital Shanghai Cancer InstituteShanghai Jiao Tong University School of Medicine

In recent yea.s, the histone methyltra.sfera.e SET doma.n conta.ning 2 (SETD2) ha. ga.nered significa.t a.tention for its involvement in ca.cinogenesis. Herein we a.m to summa.ize the resea.ch a.va.ces rega.ding SETD2 in tumors,elucida.e the role in globa. epigenetic regula.ion, highlight potentia. thera.eutic regimens for pa.ients with SETD2 deficiency, a.d outline future resea.ch directions.

关键词： METHYLa.ION