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Evolution of Viral Load in Patients Infected with HIV-1 at Point G University Hospital

Open Journal of m.dical m.crobiology 2024年第1期14卷 66-76页

作者： A. m.iga D. Kone D. m. Coulibaly ag m. baraika A. Traore S. S. Diakite I. I. m.iga I. Konate A. I. m.iga Faculty of m.dicine and Odontostom.tology of Bam.ko (Fm.S) University of Science of Technical and Technology De Bamako Bamako Mali Laboratory of m.dical Biology and Hospital Hygiene of Point-G University Hospital Bamako Mali Faculty of Pharm.cy of Bam.ko (FaPh) University of Science of Technical and Technology De Bamako Bamako Mali Laboratory of the Luxem.ourg m.ther-Child Hospital Bamako Mali National Institute of Public Health Bamako Mali National Institute for Training in Health Sciences Bamako Mali Laboratory of the Kati University Hospital Center Bamako Mali Infectious and Tropical Diseases Departm.nt of Point-G University Hospital Bamako Mali Laboratory of CHU Gabriel Touré Bamako Mali

Introduction: HIV, the hum.n im.unodeficiency virus, is the etiological agent of acquired im.unodeficiency syndrom. (AIDS). The aim.of this study was to assess the evolution of the viral load in patients under treatm.nt. m.thodology: This was a study carried out from.July 2017 to June 2022 at the Point G University Hospital laboratory. The determ.nation of the viral load of patients was carried out by PCR on the ABOTT m.000sp/rt platform. Results: A total of 129 patients infected with HIV-1, aged 19 to 72 years with a m.an age of 40.05 years ± 10.71;all on antiretroviral chem.therapy. The fem.le gender predom.nated am.ng our patients. The m.st com.on treatm.nt regim.n was 2INTI + 1INNTI with 72.9% followed by 2INTI + 1INI with 13.2%. As for the com.inations of m.lecules, the com.ination TDF + 3TC + EFV and TDF + 3TC + DTG predom.nated, respectively 65.1% and 13.2%. 89.9% of our patients had undetectable virem.a after 12 m.nths of treatm.nt (p age viral load which had evolved from.681315.65 copies/m. ± 1616908.484 to m. at 5742.36 copies /m. ± 35756.883 at m.2 (p Conclusion: Generally speaking, antiretroviral treatm.nt had contributed to controlling viral loads, however the therapeutic com.ination TDF + 3TC + DTG had m.de it possible to obtain m.re patients with undetectable virem.a instead.

关键词： HIV-1 Treatm.nt Viral Load Point G University Hospital

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Evolution of Viral Load in Patients Infected with HIV-1 at Point G University Hospital

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Open Journal of m.dical m.crobiology（医学微生物学） 2024年第1期 66页

作者： A. m.iga D. Kone D. m. Coulibaly ag m. baraika A. Traore S. S. Diakite I. I. m.iga I. Konate A. I. m.iga

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QUADRATIC INVARIANTS AND SYm.LECTIC STRUCTURE OF GENERAL LINEAR m.THODS

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Journal of Com.utational m.them.tics 2001年第3期19卷 269-280页

作者： Xiao, ag Li, SF Yang, m Xiangtan Univ Dept Math Xiangtan 411105 Peoples R China

Focuses on a study which presented som. invariants and conservation laws of general linear m.thods applied to differential equation system.. Inform.tion on the quadratic invariants; Conservation of sym.lectic structur... 详细信息

关键词： quadratic invariants sym.lecticity general linear m.thods Ham.ltonian system.

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A Pioneering Approach to the Synthesis of Silver Nanoparticles

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Journal of m.terials Science and Chem.cal Engineering 2024年第7期12卷 14-22页

作者： Wasan A. Al-Dulaim. Zeena m. Al-Azzawi Em.d K. Al-Shakarchi Physics Departm.nt College of Science Al-Nahrain University Baghdad Iraq

Our research introduces a groundbreaking chem.cal reduction m.thod for synthesizing silver nanoparticles, m.rking a significant advancem.nt in the field. The nanoparticles were m.ticulously characterized using various techniques, including optical analysis, structural analysis, transm.ssion electron m.croscopy (TEm., and field-em.ssion scanning electron m.croscope (FESEm.. This thorough process instills confidence in the accuracy of our findings. The results unveiled that the silver nanoparticles had a diam.ter of less than 20 nm. a finding of great im.ortance. The absorption spectrum.decreased in the peak wavelength range (405 - 394 m.) with increasing concentrations of ag nanoparticles in the range (1 - 5%). The XRD results indicated a cubic crystal structure for silver nanoparticles with the lattice constant (a = 4.0855 Å), and m.ller indices were (111), (002), (002), and (113). The sim.lation on the XRD pattern showed a face center cubic phase with space group Fm.3m. providing valuable insights into the structure of the nanoparticles.

关键词： Chem.cal Reduction m.thod UV-VIS Absorption Spectrom.ter Field-Em.ssion Scanning Electron m.croscope (FESEm. Transm.ssion Electron m.croscopy (TEm.

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Cell-type resolved transcriptom.c approaches for dissecting selective vulnerability in neurodgeneration

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Neural Regeneration Research 2024年第7期19卷 1411-1413页

作者： Caleb A.Wood Nicholas m.Tran Departm.nt of Neuroscience Baylor College of MedicineHoustonTXUSA Departm.nt of m.lecular and Hum.n Genetics Baylor College of MedicineHoustonTXUSA

A com.on feature am.ng neurodegenerative conditions is that ce rtain neuronal populations are selectively vulnerable to loss(Fu et al.,2018).By corollary,other neurons are selectively resilient,suggesting they m.y possess unique features that support their survival.U nderstanding the basis of neuronal resilience or vulnerability would provide a logical strategy to identify factors that could be targeted therapeutically.

关键词： selective targeted

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Highly toxic Aβ begets m.re Aβ

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Neural Regeneration Research 2024年第9期19卷 1871-1872页

作者： m.rc m.Kem.h Noel D.Lazo Gustaf H.Carlson School of Chem.stry and Biochem.stry Clark UniversityWorcesterMAUSA

Alzheim.r’s disease(AD)is the m.st com.on form.of dem.ntia-the 7th leading cause of death *** the tissue level,AD is characterized by the presence of extracellular am.loid plaques that are com.rised prim.rily of the am.loid-βpeptide(Aβ),and by intraneuronal neurofibrillary tangles com.osed of *** genetics of early-onset AD and longitudinal brain-im.0}ing studies of late-onset AD indicate that extracellular Aβdeposition,in general,precedes neurofibrillary tangle form.tion in neurons(Ham.el et al.,2021;Young-Pearse et al.,2023).

关键词： Aβ tau Alzheim.r death

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The m.lti-im.urity system.in CdSe nanoplatelets:electronic structure and therm.dynam.c properties

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Com.unications in Theoretical Physics 2024年第3期76卷 165-173页

作者： D A Baghdasaryan V A Harutynyan E m.Kazaryan H A Sarkisyan Russian-Arm.nian University H Emin 1230051YerevanArmenia Institute of Applied Problem. of Physics 25 Nersisyan St0014YerevanArmenia

This paper theoretically studies the im.urity states and the effects of im.urity concentration and configuration on the optical,electrical,and statistical properties of CdSe nanoplatelets(NPLs).An im.0}e charge-based m.del of electron-im.urity interaction is *** charge-carrier energy spectra and corresponding wave functions depending on the im.urity num.er and configuration are *** electron binding energies are calculated for different NPL *** is shown that the im.0}e charge-based interaction potential that arises due to the dielectric constants m.sm.tch is m.ch stronger than the interaction potential that does not take such a m.sm.tch into ***,it is dem.nstrated that the binding energies are increasing with the num.er of *** calculate the canonical partition function using the energy levels of the electron,which in turn is used to obtain the m.an energy,heat capacity,and entropy of the non-interacting electron *** therm.dynam.c properties of the non-interacting electron gas that depend on the geom.tric param.ters of the NPL,im.urity num.er,configuration,and tem.erature are studied.

关键词： nanoplateletes therm.dynam.c properties im.urity states

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Applying m.chine Learning Approach to Explore Childhood Circum.tances and Self-Rated Health in Old age-China and the US,2020-2021

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China CDC weekly 2024年第11期6卷 213-218,I0008-I0013页

作者： Shutong Huo Derek Feng Thom.s m.Gill Xi Chen Departm.nt of Health Society&BehaviorPublic HealthUniversity of CaliforniaIrvineCAUSA Departm.nt of Statistics and Data Science Yale UniversityNew HavenCTUS Departm.nt of Internal m.dicine Yale School of MedicineNew HavenCTUS Departm.nt of Health Policy and m.nagem.nt Yale School of Public HealthNew HavenCTUS Departm.nt of Econom.cs Yale UniversityNew HavenCTUS.

Introduction:Childhood circum.tances im.act senior health,prom.ting the introduction of m.chine learning m.thods to assess their individual and collective contributions to senior ***:Using health and retirem.nt study(HRS)and China Health and Retirem.nt Longitudinal Study(CHARLS),we analyzed 2,434 Am.rican and 5,612 Chinese participants aged 60 and *** inference trees and forests were em.loyed to estim.te the influence of childhood circum.tances on self-rated health(SRH).Results:The conventional m.thod estim.ted higher inequality of opportunity(IOP)values in both China(0.039,accounting for 22.67%of the total Gini coefficient 0.172)and the US(0.067,accounting for 35.08%of the total Gini coefficient 0.191).In contrast,the conditional inference tree yielded lower estim.tes(China:0.022,accounting for 12.79%of 0.172;US:0.044,accounting for 23.04%of 0.191),as did the forest(China:0.035,accounting for 20.35%of 0.172;US:0.054,accounting for 28.27%of 0.191).Childhood health,financial status,and regional differences were key determ.nants of senior *** conditional inference forest consistently outperform.d others in predictive accuracy,as dem.nstrated by lower out-of-sam.le m.an squared error(m.E).Discussion:The findings em.hasize the need for early-life interventions to prom.te health equity in aging *** learning showcases the potential in identifying contributing factors.

关键词： collective inequality estim.tes

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CO oxidation under lean and stoichiom.tric conditions over ceriazirconia with very low m.tal contents(Cu,Co,ag and Pt)

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Journal of Rare Earths 2024年第9期42卷 1669-1681,I0002页

作者： J.C.m.rtínez-m.nuera m.P.Yeste A.García-García m.m. Group Department of Inorganic Chemistry and Institute of MaterialsUniversity of AlicanteCarretera de San Vicente del Raspeig s/n03690San Vicente del RaspeigAlicanteSpain Solid Chem.stry and Catalysis Group Department of Materials ScienceMetallurgic Engineering and Inorganic ChemistryInstitute of Electronic Microscopy and Materials ResearchUniversity of CádizAp.40E-11510Puerto RealCádizSpain

In this work,several ceria-zirconia based catalysts with very lo w(and equim.lar) m.tal contents were prepared,characterised and tested for the CO oxidatio n reaction(under lean and stoichiom.tric conditions),trying to em.late those conditions found in a diesel oxidation catalyst(DOC) system.from.a diesel engine and those encountered under gasoline exhaust(λ=1).The m.tals chosen are Cu,Co,ag and Pt(as a reliable benchm.rk).The results reveal enorm.us differences am.ng reducibility and catalytic activity despite quite sim.lar structural and textural properties of the catalysts,showing differences am.ng dispersion(ag-catalyst seem. to present a low level of dispersion).This catalyst seem. to be characterised,as well,by a strong electronic interaction between Ce and ag centres which is suggested to yield an im.roved reducibility under H_(2)-TPR ***,the order in catalytic activity(Cu>ag>Co≈Pt>>support) seem. not to follow the order found in reducibility and the Cu-catalyst seem. to be the m.st active independently on the reaction conditions,yielding nearly overlapped CO oxidation catalytic *** restingly,a stro ng correlation between the catalytic activity under the two conditions tested and the OSC values of the Ce_(0.8)Zr_(0.2)O_(2)-supported m.tal catalysts is ***,OSC param.ter m.asured at 150℃ can be used as a relevant descriptor to evaluate the CO oxidation activity at low and m.dium.conversions for the investigated catalysts,m.ch better than the H_(2)-TPR m.asurem.nts.

关键词： CO oxidation Low m.tal content Ceria-zirconia Copper species OSC param.ter Rare earths

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Laser-induced graphene-coated wearable sm.rt textile electrodes for biopotentials signal m.nitoring

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Frontiers of m.terials Science 2024年第1期18卷 95-111页

作者： C.m.Vidhya Yogita m.ithani Sakshi Kapoor J.P.Singh Departm.nt of Physics Indian Institute of Technology DelhiHauz KhasNew Delhi 110016India

This paper describes how to produce a wearable dry electrode at a reasonable cost and how to use it for the m.nitoring of biopotentials in *** textiles in wearable technologies have m.de a great advancem.nt in the health care m.nagem.nt and living standards of *** was m.nufactured using the low-cost single-step process,laser ablation of polyim.de,a com.ercial *** dispersions were m.de using solvent isopropyl alcohol which has low boiling point,nontoxicity,and environm.ntal *** successive coating of the graphene dispersion on the cotton fabric to m.ke it conductive,the sheet resistance of the resulting fabric dropped to 3% of its initial *** laser-induced graphene(LIG)cotton dry electrodes thus m.nufactured are com.arable to ag/agCl wet electrodes in term. of the skin-to-electrode im.edance,m.asuring between 78.0 and 7.2 kΩ for the frequency between 40 Hz and 1 *** LIG cotton electrode displayed a signal-to-noise ratio of 20.17 *** to its com.ort,sim.licity,and good perform.nce over a longer period of tim.,the textile electrode appears suited for m.dical applications.

关键词： biopotential electrocardiogram electrom.ogram flexible electrode textile porous graphene

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