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Prediction of Porous Media Fluid Flow with Spatial Heterogeneity Using Criss-Cross Physics-Informed Convolutional Neural Networks

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Computer Modeling in Engineering & Sciences 2024年第2期138卷 1323-1340页

作者： Jiangxia Han Liang Xue Ying Jia Mpoki Sam Mwasamwasa felix Nanguka Charles Sangweni Hailong Liu Qian Li State Key Laboratory of Petroleum Resources and Prospecting China University of PetroleumBeijing102249China Department of Oil-Gas Field Development Engineering College of Petroleum EngineeringChina University of PetroleumBeijing102249China Exploration Production Research Institute SinopecBeijing102249China Ministry of Energy Tanzania Petroleum Development CorporationTowerDar es Salaam2774Tanzania Ministry of Energy Building Petroleum Upstream Regulatory Authority in Tanzania(PURA)Dar es Salaam11439Tanzania

Recent advances in deep neural networks have shed new light on physics,engineering,and scientific *** the data-centered viewpoint with physical simulation is one of the research *** physicsinformedneural network(PINN)is currently the most general framework,which is more popular due to theconvenience of constructing NNs and excellent generalization *** automatic differentiation(AD)-basedPINN model is suitable for the homogeneous scientific problem;however,it is unclear how AD can enforce fluxcontinuity across boundaries between cells of different properties where spatial heterogeneity is represented bygrid cells with different physical *** this work,we propose a criss-cross physics-informed convolutionalneural network(CC-PINN)learning architecture,aiming to learn the solution of parametric PDEs with spatialheterogeneity of physical *** achieve the seamless enforcement of flux continuity and integration ofphysicalmeaning into CNN,a predefined 2D convolutional layer is proposed to accurately express transmissibilitybetween adjacent *** efficacy of the proposedmethodwas evaluated through predictions of several petroleumreservoir problems with spatial heterogeneity and compared against state-of-the-art(PINN)through numericalanalysis as a benchmark,which demonstrated the superiority of the proposed method over the PINN.

关键词： Physical-informed neural networks(PINN) flow in porous media convolutional neural networks spatial heterogeneity machine learning

Factors Affecting Cotrimoxazole Prophylactic Therapy Compliance in HIV Patients Attending a Care and Treatment Clinic at Bugando Medical Centre in Mwanza, Tanzania

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Advances in Infectious Diseases 2024年第2期14卷 456-468页

作者： Stanley Mwita felix Tarimo Rahma Mbalamla Department of Pharmaceutics and Pharmacy Practice Catholic University of Health and Allied Sciences Mwanza Tanzania Department of Biochemistry Catholic University of Health and Allied Sciences Mwanza Tanzania

Introduction: Cotrimoxazole Prophylactic Therapy (CPT) compliance lowers the risk of opportunistic infections and other Acquired Immune Deficiency Syndrome (AIDS)-related diseases. The aim of this study was to examine factors that influence compliance with CPT among HIV patients in the Care and Treatment Clinic (CTC) at Bugando Medical Centre (BMC) in Mwanza, Tanzania. Methods: A descriptive cross-sectional study was conducted at the BMC between April 1, 2021, and June 30, 2021. Data were collected using face-to-face interviews and a semi-structured questionnaire. Data are presented in frequency, percentages, and cross-tabulation tables. A P-value of less than 0.05 was considered statistically significant. Results: The prevalence of compliance with CPT by self-reported measurement was 158 (63.7%). Most CPT-compliant participants were more likely to have a spouse who is familiar with CPT, have a family member who is aware of their HIV status, and be aware of the benefits of CPT. The majority of participants who complied with CPT were more likely to have experienced counseling during refill, felt that the length of time spent seeing doctors for treatment was reasonable, and received accurate information from them. Conclusion: Most adult HIV patients attending CTC at BMC were reported to be in compliance with CPT. These findings suggest that improving social support and patient-provider communication may be effective strategies for improving compliance with CPT among HIV patients.

关键词： Factors Compliance Co-Trimoxazole Prophylactic Therapy HIV/AIDS Tanzania Bugando Medical Centre

Genome-wide association mapping and genomic prediction of stalk rot in two mid-altitude tropical maize populations

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The Crop Journal 2024年第2期12卷 558-568页

作者： Junqiao Song Angela Pacheco Amos Alakonya Andrea S.Cruz-Morales Carlos Muoz-Zavala Jingtao Qu Chunping Wang Xuecai Zhang felix San Vicente Thanda Dhliwayo College of Agronomy Henan University of Science and TechnologyLuoyang 471000HenanChina International Maize and Wheat Improvement Center(CIMMYT) El BatanMexico Anyang Academy of Agricultural Sciences Anyang 455000HenanChina CIMMYT-China Specialty Maize Research Center Crop Breedingand Cultivation Research InstituteShanghai Academy of Agricultural SciencesShanghai 201403China

Maize stalk rot reduces grain yield and *** about the genetics of resistance to maize stalk rot could help breeders design effective breeding strategies for the *** prediction may be a more effective breeding strategy for stalk-rot resistance than marker-assisted *** performed a genome-wide association study(GWAS)and genomic prediction of resistance in testcross hybrids of 677 inbred lines from the Tuxpe?o and non-Tuxpe?o heterotic pools grown in three environments and genotyped with 200,681 single-nucleotide polymorphisms(SNPs).Eighteen SNPs associated with stalk rot shared genomic regions with gene families previously associated with plant biotic and abiotic *** favorable SNP haplotypes traced to tropical than to temperate progenitors of the inbred *** genotype-by-environment(G×E)interaction increased genomic prediction accuracy.

关键词： Maize stalk rot Genome-wide association mapping Haplotype analysis Genomic prediction G×E interaction

Measuring Causal Effect with ARDL-BART: A Macroeconomic Application

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Applied Mathematics 2024年第4期15卷 292-312页

作者： Pegah Mahdavi Mohammad Ali Ehsani Daniel felix Ahelegbey Mehrnaz Mohammadpour Department of Economic and Administrative Sciences University of Mazandaran Babolsar Iran Department of Economics and Management Sciences University of Pavia Pavia Italy Department of Mathematical Sciences University of Mazandaran Babolsar Iran

Modeling dynamic systems with linear parametric models usually suffer limitation which affects forecasting performance and policy implications. This paper advances a non-parametric autoregressive distributed lag model that employs a Bayesian additive regression tree (BART). The performance of the BART model is compared with selection models like Lasso, Elastic Net, and Bayesian networks in simulation experiments with linear and non-linear data generating processes (DGP), and on US macroeconomic time series data. The results show that the BART model is quite competitive against the linear parametric methods when the DGP is linear, and outperforms the competing methods when the DGP is non-linear. The empirical results suggest that the BART estimators are generally more efficient than the traditional linear methods when modeling and forecasting macroeconomic time series.

关键词： BART Model Non Parametric Modeling Machine Learning Regression Trees Bayesian Network VAR

Interventional pulmonology for chronic inflammatory airway diseases

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Chinese Medical Journal Pulmonary and Critical Care Medicine 2024年第3期2卷 171-181页

作者： Han Yang Si Chen Jiayuan Sun felix J.F.Herth Department of Respiratory and Critical Care Medicine Shanghai Chest HospitalShanghai Jiao Tong University School of MedicineShanghai 200030China Department of Respiratory Endoscopy Shanghai Chest HospitalShanghai Jiao Tong University School of MedicineShanghai 200030China Shanghai Engineering Research Center of Respiratory Endoscopy Shanghai 200030China Pneumology and Critical Care Medicine ThoraxklinikUniversity of HeidelbergHeidelberg 69126Germany Translational Lung Research Center Heidelberg German Center for Lung ResearchHeidelberg 69126Germany

Chronic inflammatory airway diseases,such as chronic bronchitis,chronic obstructive pulmonary disease,emphysema,and bronchial asthma,pose significant healthcare *** treatments offer promise as valuable complements to the optimal medical therapy recommended by the Global Initiative for Chronic Obstructive Lung Disease guideline and the Global Initiative for Asthma *** directly accessing the airways,these minimally invasive procedures enable precise *** encompass a wide range of techniques including bronchial thermoplasty and targeted lung denervation for both chronic obstructive pulmonary disease and severe asthma,bronchoscopic lung volume reduction(including the use of endobronchial valves,coils,and bronchoscopic thermal vapor ablation),airway bypass and peripheral stent placement for emphysema,bronchial rheoplasty and spray cryotherapy for chronic bronchitis,and other emerging *** interventional treatments aim to improve patients’symptoms by reducing lung volume,alleviating hyperinflation,eliminating vagal innervation,disrupting hyperplastic goblet cells and thus reducing excessive mucus secretion,and weakening submucosal smooth *** review highlights the potential advantages of interventional treatments for chronic inflammatory airway diseases and discusses relevant techniques tailored to specific disease *** overall aim is to assist interventional pulmonologists in selecting the most appropriate techniques for individual patients.

关键词： Chronic inflammatory airway disease Chronic obstructive pulmonary disease Asthma Emphysema Bronchoscopic lung volume reduction Targeted lung denervation

Management of a Huge Ovarian Cyst in Pregnancy at the Douala General Hospital, Cameroon: A Case Report and Review of the Literature

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Advances in Reproductive Sciences 2024年第3期12卷 165-178页

作者： Fidelia Mbi Kobenge felix-Adolphe Elong Emenguele Pascale Mpono Thomas Obinchemti Egbe Department of Obstetrics and Gynecology Douala General Hospital Douala Cameroon Faculty of Health Sciences University of Bamenda Bamenda Cameroon Faculty of Health Sciences University of Buea Buea Cameroon Faculty of Medicine and Biomedical Sciences University of Yaound 1 Yaound Cameroon Department of Obstetrics and Gynecology CHRACERH Yaound Cameroon

Background: Ovarian cysts in pregnancy are common and are usually small benign functional cysts (corpus luteum and theca-lutein cysts) that usually resolve spontaneously between 14 and 16 weeks of gestation. However, large ovarian cysts are rare in pregnancy, with an incidence of 0.2% - 2%, and most of them are benign. The first-line diagnostic modality is ultrasonography. Complications of ovarian cysts in pregnancy include miscarriage, ovarian torsion, cyst rupture, etc. Laparotomy is the treatment modality commonly used in our setting, and histopathologic diagnosis is important for the prognosis of the treatment. Case Presentation: MC is a 32-year-old G3P2002 married housewife of the Bakweri tribe who was referred to our department because of progressive abdominal discomfort and shortness of breath for 1 month’s duration. Her medical history is consistent with two normal vaginal deliveries at term and the use of implants (for contraception) until one month prior to the index pregnancy. Her booking visit was at 16 weeks gestation at a primary (missionary) healthcare facility, and she underwent ultrasonography and was diagnosed with a singleton viable intrauterine pregnancy and a simple septate cystic mass measuring 17 cm situated on top of the uterus, appearing to originate from the left ovary. She was referred to seek the expertise of an obstetrician-gynecologist, but she came to our department at 35 weeks gestation and underwent cesarean birth at 37 weeks gestation. In the pathological review, serous cystadenoma was diagnosed, and there were no positive findings in peritoneal cytology. Conclusion: The ultrasonographic diagnosis of the huge ovarian cyst in the index case was after 16 weeks gestation because of her late booking visit at 16 weeks gestation. The index case deferred referral to the obstetrician because of a lack of finances, came to our department at 35 weeks gestation because of abdominal pain that may have resulted from a torsion of the ovarian cyst

关键词： Ovarian Cyst Ultrasonography Magnetic Resonance Imaging Histopathology Pregnancy Cesarean Section

Effect of Tillage Practices on Hydro-Physical Properties of Soils in a Rice-Grown Environment in North Central Nigeria

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Journal of Environmental Protection 2024年第5期15卷 527-536页

作者： Ebierni Akpoebidimiyen Otuaro John Jiya Musa felix Oguche Abayomi Ibrahim Kuti Abubakar Ndaman Civil Engineering Department Maritime University Okerenkoko Nigeria Department of Agricultural and Bioresources Engineering Federal University of Technology Minna Nigeria Institute of Water and Environmental Management Faculty of Agricultural and Food Sciences and Environmental Management University of Debrecen Boszormenyi St Hungary

This study details soil’s physical and chemical properties in a rice-grown environment in Minna environs Niger State, Nigeria, under different soil and water conservation practices. Soil samples were collected at 0 - 10 cm, 10 - 20 cm and 20 - 30 cm, respectively, using a soil auger to determine their physical and chemical properties such as moisture content, particle size, bulk density, particle density, porosity and organic matter. The textural classification determined the percentage dominance of the soil types in each study site location. The moisture content of site 1 ranged between 14.3% to 13.7%, site 2 ranged between 13.2% to 10.2%, site 3 ranged between 15.4% to 13.2%, site 4 ranged between 15.6% to 13.6% and site 5 ranged between 16.1% to 10.9%. The clay content of sites 3, 4 and 5 is higher than that of sites 1 and 2, while the silt contents of sites 1, 2 and 3 are higher than that of sites 4 and 5. The mean value of soil organic carbon from each study location was 2.37%, 2.03%, 2.43%, 2.07% and 2.17% for sites 1, 2, 3, 4, and 5, respectively. Therefore, site 1 is susceptible to erosion because of poor infiltration rate and well-ploughed or cultivated land by the tractor (harrowed). The particle sizes analysis indicated that the soil type in Site 1 and Site 2 is mainly sandy loam, while Site 3 and Site 5 are mainly loamy and predominantly clay loam in Site 4.

关键词： Degradation Erosion Fertility Irrigation Management

Aurora B promotes the CENP-T–CENP-W interaction to guide accurate chromosome segregation in mitosis

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Journal of Molecular Cell Biology 2024年第2期16卷 11-23页

作者： Wei Liu Zhen Dou Chunyue Wang Gangyin Zhao Fengge Wu Chunli Wang felix Aikhionbare Mingliang Ye Divine Mensah Sedzro Zhenye Yang Chuanhai Fu Zhikai Wang Xinjiao Gao Xuebiao Yao Xiaoyu Song Xing Liu MOE Key Laboratory for Cellular Dynamics Center for Advanced Interdisciplinary Science and Biomedicine of IHMUniversity of Science and Technology of China School of Life SciencesHefei 230027China Keck Center for Cellular Dynamics and Organoids Plasticity AtlantaGA 30310USA Anhui Key Laboratory for Cellular Dynamics and Chemical Biology Hefei National Research Center for Interdisciplinary Sciences at the MicroscaleHefei 230026China National Chromatographic Research and Analysis Center Chinese Academy of SciencesDalian 116023China

Accurate chromosome segregation in mitosis depends on kinetochores that connect centromeric chromatin to spindle *** are captured by individual microtubules via a kinetochore constitutive centromere-associated network(CCAN)during chromosome *** contains 16 subunits,including CENP-W and ***,the molecular recognition and mitotic regulation of the CCAN assembly remain ***,we revealed that CENP-W binds to the histone fold domain and an uncharacterized N-terminal region of *** B phosphorylates CENP-W at threonine 60,which enhances the interaction between CENP-W and CENP-T to ensure robust metaphase chromosome alignment and accurate chromosome segregation in *** findings delineate a conserved signaling cascade that integrates protein phosphorylation with CCAN integrity for the maintenance of genomic stability.

关键词： mitosis kinetochore Aurora B CENP-T CENP-W phosphorylation

Factors Impacting Benefits of Participatory Forest Management in Upper Imenti Forest, Meru County, Kenya

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Open Journal of Forestry 2024年第3期14卷 183-196页

作者： Josephine Kamene Musyoki Lamech felix Mogambi Ming’ate Joseph Muriithi Mbuvi Tito Edward Musingo Joram Kagombe Kenya Forestry Research Institute Nairobi Kenya Department of Environmental Studies and Community Development Kenyatta University Nairobi Kenya

This study focused on identifying factors affecting the benefits of Participatory Forestry Management (PFM) income generating activities in Upper Imenti Forest and whether they are dependent on status of participation in forest management through membership of Community Forest Association (CFA) or not. Cross-sectional survey research design was applied for collecting quantitative data using a semi-structured questionnaire administered to 384 households stratified on the basis of PFM participation status. Qualitative data was collected through focused group discussions using a checklist and key informant interviews using an interview schedule. Using Statistical Package for Social Sciences version 25, Binomial regression with Wald Chi-square was analyzed to identify factors perceived to be significantly influencing benefits for PFM participants and Pearson Chi-square to compare factors perceived to be affecting PFM and non-PFM participants. CFA members participation in PFM was significantly and positively affected by benefits of PFM income generating activities and forest products accessed in the forest. Benefits linked to Plantation Establishment for Livelihood Improvement System (PELIS) for CFA members were significantly reduced by enforcement of moratorium policy since February 2018, diseases and pests, poor PELIS guideline adherence and animal damage. Benefits related to state forest access for firewood by the CFA members were negatively influenced by the moratorium policy. Diseases and pests affected benefits associated with bee keeping significantly. Comparing factors under different PFM participation status, crop production was significantly affected by policy changes, pest and diseases, animal damage and PELIS guideline adherence for CFA members than for Non-CFA members. Policy changes also affected the CFA members significantly in firewood collection and access to fodder in the state forest than the Non-CFA members. Hence, sustainable community participation

关键词： Participatory Forest Management Community Forest Association Sustainable Community Participation Access to Forest Products Moratorium Policy Income Generating Activities