检索结果-南通市图书馆

Asian Pacific Journal of Tropical Biomedicine 2012年第10期2卷 774-781页

作者： Stephen adeniyi Adefegha Ganiyu Oboh Department of Biochemistry Federal University of TechnologyAkure

Objective:To investigate and compare the inhibitor)'properties)of free and bound phenolic extracts of clove bud against carbohydrate hydrolyzing enzymes(alpha-amylase&alphaglucosidase)and Fe^(2+)-induced lipid peroxidation in rat pancreas in ***:The free phenolics were extracted with 80%.(v/v)acetone,while bound phenolics were extracted from the alkaline and acid hydrolyzed residue with ethyl ***,the interaction of the extracts with alpha-amylase and alpha-glucosidase was subsequently ***,the total phenolic contents and antioxidant activities of the extracts were ***:The result revealed that both extracts inhibited alpha-amylase and alpha-glucosidase in a dose-dependent ***,the alpha-glucosidase inhibitory activity of the extracts were significantly(P<0.05)higher than their alpha-amylase inhibitory *** free phenolics(31.67 mg/g)and flavonoid(17.28 mg/g)contents were significantly(P<0.05)higher than bound phenolic(23.52 mg/g)and flavonoid(13.70 mg/g)*** extracts also exhibited high antioxidant activities as typified by their high reducing power,LI diphenyl-2-picrylhydrazyl(DPPH)and 2,2-azinobis-3-ethylbenzo-thiazoline-6-sulfonate(ABTS)radical scavenging abilities,as well as inhibition of Fe^(2+)-induced lipid peroxidation in rat pancreas in ***:This study provides a biochemical rationale by which clove elicits therapeutic effect on type 2 diabetes.

关键词： Alpha-amylase Alpha-glucosidase Fe2+-induced lipid peroxidation Pancrea Phenol Antioxidant

Genomic and transcriptomic analyses reveal selection of genes for puberty in Bama Xiang pigs

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Zoological Research 2018年第6期39卷 424-430页

作者： Yang Yang adeniyi C.Adeola Hai-Bing Xie Ya-Ping Zhang State Key Laboratory of Genetic Resources and Evolution Yunnan Laboratory of Molecular Biology of Domestic AnimalsKunming Institute of ZoologyChinese Academy of Sciences Kunming College of Life Science University of Chinese Academy of Sciences

The Bama Xiang pig （BMX） Chinese indigenous breed is a famous early-maturing with a two-end black coat To uncover the genetic basis of the BMX phenotype, we conducted comparative genomic analyses between BMX and East Asian wild boars and Laiwu pigs, respectively. Genes under positive selection were enriched in pathways associated with gonadal hormone and melanin synthesis, consistent with the phenotypic changes observed during development in BMX pigs. We also performed differentially expressed gene analysis based on RNA-seq data from pituitary tissues of BMX and Large White pigs. The CTTNBP2NL, FRS2, KANK4, and KATNAL1 genes were under selection and exhibited expressional changes in the pituitary tissue, which may affect BMX pig puberty. Our study demonstrated the positive selection of early maturity in the development of BMX pigs and advances our knowledge on the role of regulatory elements in puberty evolution in pigs.

关键词： Puberty Bama Xiang pig Pituitary Differentially expressed genes

High Fat Diet Alteration of Gut Microbiota Impacts Learning, Memory and Anxiety Response in Mice: Cannabidiol and Omega 3 Possible Remedies

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Advances in Alzheimer's Disease 2022年第1期11卷 1-9页

作者： Innocent Abi Moses Ashiekaa Eugenia Abi Olasupo Stephen adeniyi Linus Chia Saalu Department of Physiology College of Health Sciences Benue State University Makurdi Nigeria Department of Biochemistry Faculty of Science University of Agriculture Makurdi Nigeria Department of Human Anatomy College of Health Sciences Benue State University Makurdi Nigeria

Chronic intake of High Fat Diet (HFD) has the potential of causing a number of metabolic disorders. It is also theorized to be involved in perturbation of gut microbiota. Cannabididol (CBD) and omega 3 are known to possess a number of medicinal usefulness. Their combined use in experimental interventions is quite limited. A total of 15 mice were used for this research divided into three groups of five animals each. Group 1 was administered water and normal chow ad libidum. Group 2 had HFD and water ad libidum. Group 3 had HFD plus CBD (10 mg/kg) and omega 3 (200 mg/kg) all for a total of 12 weeks. They were tested on the elevated plus maze (EPM) and average entry time into the closed arm was recorded. They were also tested on the Y-maze and spontaneous alternations were measured. Thereafter animals were sacrificed and faecal content in the caecum was collected in sterile bottles and cultured for E. coli count. It was found that HFD group at p value E. coli count (2.4 × 106 ± 4.5) compared to group 1 (1.4 × 106 ± 5.6) and group 3 (1.42 × 106 ± 6.3). The findings revealed that HFD enhanced gut E. coli overgrowth which was reduced by CBD and Omega 3. The memory impairment and anxiety induction by HFD was also significantly ameliorated by CBD and omega 3. E. coli known to be implicated in dementia induction was suppressed by the interventions. Possible mechanisms proposed are actions of CBD and omega 3 on CB1, TRVP and 5HT receptors in reducing anxiety and their antioxidant/anti-inflammatory actions in mitigating the neuro-inflammatory effect of HFD and immune hyperstimulation of E. coli via the gutbrain-axis.

关键词： HFD Learning Memory CBD Omega 3 Anxiety EPM

Omega 3 Fatty Acid and Cannabidiol Prolong Lifespan and Ameliorates Brain Ischaemia in Mice Fed Chronic High Fat Diet

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Behavioral and Brain Science 2022年第7期12卷 335-341页

作者： Innocent Abi Aver Maria Yongu Ugbudu George Tersoo Olasupo Stephen adeniyi Linus Chia Saalu Department of Physiology College of Health Sciences Benue State University Makurdi Nigeria Department of Anatomy College of Health Sciences Benue State University Makurdi Nigeria

Diets these days contain more fats. High fat diet (HFD) is a model of unhealthy eating in experimental animals. It is known to induce inflammatory responses and oxidative stress. Cannabidiol (CBD), the non-psychoactive component of Cannbis sativa has been legalized for medicinal use in many countries of the world. Omega 3 fatty acid, commonly found in fish oil is medicinal and necessary for brain development. The antioxidant and neuroprotective functions of CBD and omega 3 have made them relevant in many researches. In this study, 45 mice were used and divided into three groups of 15 animals each: Group 1 (normal feed and water ad libidum);Group 2 (HFD ad libidum);Group 3 (HFD + CBD + Omega 3) for 16 weeks. Thereafter, five animals from each group were selected and their frontal lobes were harvested for histological analyses using H and E staining. The remaining mice were allowed to feed on normal diet and observed till death. At the end, HFD significantly reduced life span (57.4 ± 0.3) when compared to control (78.9 ± 1.6) and HFD + CBD + omega 3 group (74.5 ± 0.8) at p < 0.05. HFD also caused significant brain ischemic damage, neuronophagia and significant perivascular oedema. CBD + Omega 3 induced significant astrocytosis compared to control and HFD group. The immune stimulation by the CBD + Omega 3 could be responsible for tissue survival and longevity by protection from inflammatory and oxidative injuries. Ischaemic tissue death could have been prevented by amelioration of artheroma formation due to HFD. Further studies will be required to ascertain other possible mechanisms behind these findings.

关键词： Omega 3 CBD HFD Lifespan Astrocytosis

Assessment of two persistent bioaccumulative toxicants in the UNESCO protected river of Osun-Osogbo, Nigeria

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Ecological Processes 2017年第1期6卷 323-330页

作者： Emmanuel O.Akindele Godwin O.Olutona Oyeshina G.Oyeku Akinkunle V.adeniyi Department of Zoology Obafemi Awolowo UniversityIle-IfeNigeria Department of Chemistry and Industrial Chemistry Bowen UniversityIwoNigeria Department of Biological Sciences Bowen UniversityIwoNigeria Institute of Ecology and Environmental Studies Obafemi Awolowo UniversityIle-IfeNigeria

Introduction:Osun River dissecting the Osun-Osogbo Sacred Grove,though inscribed on the World Heritage List,has been rarely assessed for biodiversity values or *** this study,we investigated the concentrations of Cu and Zn in the benthic sediments and two dominant gastropod species(Melanoides tuberculata and Lanistes varicus)of the Osun *** sediment and gastropod samples were collected on quarterly basis from June 2015 to March 2016 along the longitudinal stretch of the *** samples were digested and analysed for Cu and Zn using the atomic absorption ***:With the exception of September sampling period,the two metals recorded higher values in the animals than in the ***(1.23±0.81μg/g)was much lower(p<0.01)than zinc(6.29±2.15μg/g)in the benthic *** the same vein,Cu was significantly lower(p<0.01)than Zn in both *** metals recorded much lower values than their average concentrations in the Earth’s crust as well as the recommended limits for freshwater ***,*** recorded higher bioaccumulation factor than ***:Findings from this study suggest that both metals posed no toxicological risk to the freshwater system of Osun *** of both metals in the sediments as well as their accumulation factors in both gastropod species were indicative of an unimpacted freshwater system.

关键词： :Accumulation Benthic sediments Contamination Ecotoxicology Heavy metals Freshwater gastropods

Associations of autozygosity with economic important traits in a cross of Eurasian pigs

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Genetics and Genomics 2023年第3期50卷 216-220页

作者： Lin Tao Li-Gang Wang adeniyi C.Adeola Long-Chao Zhang Lian-Wei Li Qing-Long Li Dao-Ji Cen Chen Yan Zhan-Shan Ma Li-Xian Wang Hai-Bing Xie Ya-Ping Zhang State Key Laboratory of Genetic Resources and Evolution&Yunnan Laboratory of Molecular Biology of Domestic Animals Kunming Institute of ZoologyChinese Academy of SciencesKunmingYunnan 650223China Kunming College of Life Science University of Chinese Academy of SciencesKunmingYunnan 650204China Institute of Animal Science Chinese Academy of Agricultural SciencesBeijing 100193China Computational Biology and Medical Ecology Lab State Key Laboratory of Genetic Resources and EvolutionKunming Institute of ZoologyChinese Academy of SciencesKunmingYunnan 650223China State Key Laboratory for Conservation and Utilization of Bioresource in Yunnan School of Life ScienceYunnan UniversityKunmingYunnan 650091China

Inbreeding depression(ID)refers to the undesirable effects of inbreeding(mating of relatives)on fitness-associated phenotypes(Charlesworth and Willis,2009).ID on production,reproduction,and health traits is relevant to industrial profitability,making it important in animal *** of homozygosity(ROH)is a good measure of inbreeding and autozygosity(the inheritance of two copies of an ancestral allele)(Alkuraya,2013).

关键词： Eurasian profit reproduction

Nanomaterial-based biosorbents:Adsorbent for efficient removal of selected organic pollutants from industrial wastewater

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Emerging Contaminants 2022年第1期8卷 46-58页

作者： Hussein.K.Okoro Sadanand Pandey Clement O.Ogunkunle Catherine J.Ngila C.Zvinowanda Ismaila Jimoh Isiaka A.Lawal Muyiwa M.Orosun Adewale George adeniyi Analytical-Environmental Research Group Department of Industrial ChemistryFaculty of Physical SciencesP.M.B.1515University of IlorinPostal Code 240003IlorinNigeria Department of Chemistry College of Natural ScienceYeungnam University280 Daehak-RoGyeongsanGyeongbuk38541Republic of Korea Environmental Botany Unit Department of Plant BiologyUniversity of IlorinIlorinNigeria Analytical-Environmental and Membrane Nanotechnology Research Group Department of Chemical SciencesFaculty of ScienceUniversity of JohannesburgP.O.Box 17011Doornfontein2028JohannesburgSouth Africa Psychometrics Department JAMBNigeria Chemistry Department Faculty of Applied and Computer ScienceVaal University of Technology1900VanderbijlparkSouth Africa Health and Environmental Physics Research Group Physics DepartmentUniversity of IlorinIlorinNigeria The African Academy of Sciences P.O.Box 24916-00502 NairobiKenya Physical Address:8 Miotoni LaneKarenNairobiKenya Department of Chemical Engineering Faculty of EngineeringUniversity of IlorinPMB1515IlorinNigeria

The contamination of the environment by organic pollutants is a major risk factor,particularly for developing *** organic pollutants(SOPs)like the phenolic compounds,polyaromatic hydrocarbons(PAHs),pesticides,and herbicides pose serious environmental and health issues owing to their toxic characteristics and poor *** from their potential mutagenicity,carcinogenicity,tetragenicity and high body accumulation,these pollutants have become an increase concern *** is a promising alternative strategy for removing organic pollutants during water purification *** have several advantages such as simplicity of operation,good sorption capacity,high recoverability and *** a result,the focus and novelty of this review is on recent trends in the use of biosorbents,with a particular emphasis on the removal of SOPs from *** also cover use of bacteria biosorbents,fungal,algae and chitosan/chitin *** from that,we have also reviewed various classes of SOPs,their levels in the environment,classification and available characteristics techniques suitable for the adsorption experiments of these nanocomposites *** addition,we have provided comprehensive explanations and conclusions on possible future application of biosorbents and the mechanism of adsorption of these materials for removal of these SOPs from wastewater during water purification processes.

关键词： Biosorbents Adsorption Organic pollutants Biosorption Wastewater

Yohimbine in the treatment of orgasmic dysfunction

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asian Journal of Andrology 2007年第3期9卷 403-407页

作者： Ade A. adeniyi Giles S. Brindley John P. Pryor David J. Ralph Institute of Urology and Nephrology London W1P 7EY UK I02 Ferdene Road London SE24 OAA UK

Aim： To study the effect of yohimbine in the treatment of men with orgasmic dysfunction. Methods： A 20-mg dose of yohimbine was first given to 29 men with orgasmic dysfunction of different aetiology in the clinic. Patients were then allowed to increase the dose at home （titration） under more favourable circumstances. The outcome and side effects were subsequently assessed. Results： The patients were classified into three groups of orgasmic dysfunction： primary complete （13）, primary incomplete （8） and secondary （8）. Nocturnal emissions were present in 75%, 40% and 50% of patients in the above groups, respectively （overall average 62%）. The men presented because of fertility problems （52%） or because they wanted to experience the pleasure of orgasm （48%）. Of the 29 patients who completed the treatment, 16 managed to reach orgasm and were able to ejaculate either during masturbation or sexual intercourse. A further three achieved orgasm, but only with the additional stimulation of a vibrator. A history of preceding nocturnal emissions was present in 69% of the men in whom orgasm was induced but only 50% who failed treatment. Of the patients, two have subsequently fathered children （one set of twins） and another 3 men were also cured. Side effects were not sufficient to cause the men to cease treatment. Conclusion： Yohimbine is a useful treatment option in orgasmic dysfunction.

关键词： Yohimbine anorgasmia orgasm orgasmic dysfunction impotence ejaculation

Students＇ Self-Concept, Knowledge of Verbal Reasoning Skill and Learning Readiness as Correlate of Achievement in Civic in Senior Secondary Schools in Osun State, Nigeria

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Psychology Research 2017年第1期7卷 50-56页

作者： Babatunde adeniyi Adeyemi Obafemi Awolowo University Ile Ife Osun State Nigeria

Thermochemical recycling of waste disposable facemasks in a non‑electrically powered system

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Low-carbon Materials and Green Construction 2023年第1期1卷 146-156页

作者： Kingsley O.Iwuozor Ebuka Chizitere Emenike Agbana Abiodun Stephen Otoikhian Shegun Kevin Joy Adeleke Adewale George adeniyi Department of Pure and Industrial Chemistry Nnamdi Azikiwe UniversityP.M.B.5025AwkaNigeria Department of Chemical Engineering University of IlorinP.M.B.1515IlorinNigeria Edo State University UzairueNigeria Chemical Engineering Department Landmark UniversityOmu‑AranNigeria.

2019年新冠病毒肆虐,为更好的防护和疫情管理,人们使用了大量的塑料基个人防护用品(PPE)。然而,大量生产和使用个人防护用品给环境造成巨大的压力,特别对发展中国家和不发达国家。因此,许多科研人员研究如何有效且低成本回收这些废弃材... 详细信息

2019年新冠病毒肆虐,为更好的防护和疫情管理,人们使用了大量的塑料基个人防护用品(PPE)。然而,大量生产和使用个人防护用品给环境造成巨大的压力,特别对发展中国家和不发达国家。因此,许多科研人员研究如何有效且低成本回收这些废弃材料的技术,例如针对一次性口罩。以前的研究聚焦于使用电力反应堆进行热化学转换,然而这些反应堆不能在电力供应不足的地区使用。在本文中,作者利用生物质动力反应器将废弃的一次性口罩和杏树叶转化为混合生物炭。该反应器由生物质提供燃料动力,相对便宜、使用简单、环保,并可经过改造后制备生物炭。持续100分钟的共同燃烧碳化过程可得到46%的生物炭产率,高于其他研究人员获得的生物炭产率。随后,对得到的生物炭进行表征以确定其性能。红外光谱分析表明,生物炭中含有烯烃、炔烃、羟基、胺、羰基等官能团。能量色散X射线光谱分析表明,生物炭主要由碳、碲、氧和钙组成,其含量分别为57%、19%、9%和7%。加入废弃的一次性口罩共同燃烧制备生物炭,能有效降低制备而成的生物炭材料的表面积和孔隙率。

关键词：生物炭生物质 Covid-19 口罩热化学转换