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Open Journal of Pediatrics 2023年第6期13卷 831-837页

作者： Aichata Keita Bory Traoré adama dembélé Rokiatou Diarra Mariam Diarra Elmouloud M. Cissé Mariam Kané Bakary Coulibaly Hawa Konaré Reference Health Center of the Commune VI Bamako Mali Department of Paediatrics CHU Gabriel Touré Bamako Mali Bamako Dermatology Hospital Bamako Mali

Acrodermatitis enteropathica is a rare autosomal recessive genetic disorder characterised by periorificial dermatitis, alopecia and diarrhoea. It is caused by a mutation in the gene that codes for a membrane protein that binds zinc. We report a case in a 7-month-old girl, admitted with altered general condition and scaly, pustular erythematous lesions, initially located in the occipital and cervical regions, and secondarily inguinal and on the knees. Management and outcome in this patient? Genetic assay was not available to confirm this rare genetic disease. A delay in establishing the diagnosis and a disastrous outcome did not save the patient despite the administration of zinc.

关键词： Enteropathica Acrodermatitis Necrotizing Fasciitis Infant

Mode B Ultrasound in the Study of the Posterior Segment in the Medical Clinic “Marie Curie” in Bamako

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Open Journal of Medical Imaging 2022年第3期12卷 138-146页

作者： Traoré Ousmane Bagayoko Ousmane Lansenou Sanogo Souleymane dembélé Mamadou Diallo Ousmane Wélé Diallo Mahamadou Sidibé Siaka Keita adama Diaman Radiology Department of the Medical Clinic “Marie Curie” Bamako Mali Radiology Department of the Center Hospitalo-Universitaire “le Point G” Bamako Mali Radiology Department of the Mother-Child Hospital Center “Luxembourg” Bamako Mali Radiology Department of the Medical Clinic “Diafounou” Bamako Mali Radiology Department of the “Gabriel Toure” University Hospital Center Bamako Mali

Introduction: The study of the posterior segment of the eye has nowadays become one of the most frequent indications for diagnostic ultrasound in the ophthalmological field. The objective of this work is to contribute to the improvement of the diagnostic management of pathologies of the posterior segment of the eye in the radiology department of the medical clinic “Marie Curie” in Bamako. Material and Methods: This was a cross-sectional study carried out in the medical imaging department from January 2020 to January 2022. It concerned all patients who presented for the study of the ocular posterior segment on ultrasound. Results: Fifty-two (52) patients out of a total of 109 were included in the study, i.e. a frequency of 47.70%. The average age was 33.90 with the extremes ranging from 05 years to 75 years. The male sex dominated with a frequency of 69.23%. Ocular ultrasound was prescribed mainly by ophthalmologists (100%). In the study of the posterior segment, preoperative assessment represented the most frequent indications with respectively 55.76% and 23.10%. Retinal detachment and vitreous hemorrhage were the most found lesions on ultrasound with 50% and 34.61% respectively. Conclusion: Ocular ultrasound is accessible in Bamako and has allowed the study of the posterior segment of the eye. It occupies an important place in the study and management of ocular pathologies of the posterior segment.

关键词： Ultrasound Posterior Segment of the Eye Medical Clinic “Marie Curie” Bamako

COVID-19 and the Vascular Elderly Subject: Illustration of Therapeutic Management with Corticosteroids in an Elderly Diabetic Patient with COVID-19

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Open Journal of Clinical Diagnostics 2024年第1期14卷 1-6页

作者： Ibrahima Amadou demb.le Abrar-Ahmad Zulfiqar Romuald Nounga Nyanke Sékou Landoure Stéphane Loique Djeugoue adama Sinayoko Nouhoum Kone Paul Antoni Amadou Nouroudine Rosunee Ahsveen Yacouba Koné Aoua Diarra Tania Mekuiko Ngeupi Mamadou Cissoko Mamadou Mallé Keïta Kaly Djibril Sy Djénébou Traoré Didier Mukéba Tshialala Assétou Soukho Kaya Emmanuel Andres Internal Medicine Department Medical Clinic B University Hospital Center of Strasbourg Strasbourg France Internal Medicine Department University Hospital Center Point G Bamako Mali Faculty of Medicine and Odontostomatology University of Sciences Techniques and Technologies of Bamako Bamako Mali Faculty of Medicine Pharmacy and Public Health University of Mbuji-Mayi Democratic Republic of Congo

Introduction: The severity of Sars-Cov-2 infection is associated with the development of acute respiratory distress syndrome (ARDS). The progression to ARDS appears to be driven by a major inflammatory mechanism potentially sensitive to corticosteroids. Observation: This article describes the case of an elderly patient was admitted to emergency departments for intense asthenia, accompanied by motor diarrhoea, dyspnoea with desaturation in ambient air, in a context of strong suspicion of infection linked to COVID-19. The article also reviews the existing literature on the diagnosis and treatment of this severe form of the disease. Conclusion: Corticosteroids, and in particular dexamethasone, have been shown to be effective in the management of patients with COVID-19, an oxygen-releasing disease.

关键词： COVID-19 Diabetes Mellitus Elderly person Corticosteroids Internal Medicine

Refractive State and Macular Abnormalities at Oct in Albino at Chu Iota

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Open Journal of Ophthalmology 2023年第3期13卷 267-272页

作者： Assiatou Simaga Mohamed Kolé Sidibé Ibrahima Conaré Nana Wangara Seydou Diallo Founè Keïta adama dembélé Nephthali Gnangourou Nouhoum Guirou Seydou Bakayoko Kalilou Ibrahim Gakou Hamidou Ibrahim Diepkilé Jeremy dembélé Institute of Ophthalmology and Tropical Africa (IOTA) Bamako Mali

Introduction: A rare genetic disease, albinism is globally characterized by specific deficits of the visual system associated with a variable hypopigmentation phenotype depending on the disruption of melanin production [1]. It is linked to a hereditary defect in the biosynthesis of melanin. Disease results in a generalized decrease in the pigmentation of the appendages, skin and eyes [2]. The aim of this study is to determine the different refractive errors and the different macular anomalies during the OCT examination in oculocutaneous albinism at the CHU-IOTA. Patients and Method: We conducted a prospective study in patients over 10 years of age with oculocutaneous or ocular albinism who consulted at the CHU-IOTA between July 1, 2020, and September 30, 2021. Results: Over the period, 105 cases of oculocutaneous albinism were collected out of a total of 42,024 consultations, which corresponds to a frequency of 0.2%. The average age was 26.2 years, (11 years to 48 years). The sex ratio was 1.6. Astigmatism was the most found refractive error in 50.48% of cases, followed by myopia in 29.52% of cases and farsightedness in 20% of cases. The macular thickness between 251 - 350 was the most commonly found in both eyes, i.e. 47.25% on the right and 53.55% on the left. The bulging macula was the most frequent pathology on the OCT at the level of the two eyes, i.e. 41.42% on the right and 50.6% on the left. Conclusion: Following the visual impairments linked to albinism, early optical care and access to OCT are necessary. Thus the accompaniment of a subject with albinism and associations of albinism must be global and meet specific needs, in order to prevent or avoid ocular complications.

关键词： Refractive Defects Macula OCT Albinos CHU-IOTA

Self-Medication during Eye Affections among Consultant Patients at Chu-Iota

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Open Journal of Ophthalmology 2023年第2期13卷 256-262页

作者： Assiatou Simaga Mohamed Kolé Sidibé Nana Wangara Seydou Diallo Ibrahima Conaré Founè Keïta adama dembélé Nouhoum Guirou Seydou Bakayoko Institute of Ophthalmology and Tropical Africa (IOTA) Bamako Mali

Introduction: According to the World Health Organization (WHO), self-medication consists in the fact that an individual resorts to a drug, on his own initiative or that of a loved one, with the aim of treating an ailment or a symptom that he identified himself without having recourse to a health professional. Self-medication involves the use of medicinal products by the consumer to treat self-recognized disorders or symptoms, or the intermittent or continued use of a medication prescribed by a physician for chronic or recurring diseases or symptoms. The aim of this study is to determine the different characteristics of ophthalmic self-medication at the CHU-IOTA. Patients and Method: We conducted a prospective study in patients of any age who resorted to ophthalmological self-medication before the first consultation or during the ophthalmological care of consulting patients at the CHU-IOTA between January 1 and July 31, 2021. Results: Over the period, 521 cases of ophthalmological self-medication were collected out of a total of 24,512 consultations, which corresponds to a frequency of 2.12%. The average age was 37.7 years, [2 months - 78]. The sex ratio was 0.50. Economic factors were the main factor mentioned, 66.79%. Corticosteroids accounted for 45.26% of the pharmacological class with dexamethasone/neomycin eye drops being the most widely used, i.e. 22.94%. The most common complication was corticosteroid-induced ocular hypertension on ametropia, i.e. 15.54%. Our patients were 68.13% educated. Among his educated patients 53.35% had no knowledge of the products. Conclusion: Given the harm associated with this practice, awareness and information campaigns aimed at the population, caregivers and pharmacists or pharmacy vendors are necessary in order to reduce the frequency of the practice of self-medication.

关键词： Self-Medication Conditions Eye CHU-IOTA

Prediction of selected biodiesel fuel properties using artificial neural network

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Frontiers in Energy 2015年第4期9卷 433-445页

作者： Solomon O. GIWA Sunday O. ADEKOMAYA Kayode O. adama Moruf O. MUKAILA Department of Agricultural and Mechanical Engineering College of Engineering and Environmental Studies Olabisi Onabanjo University lbogun Campus Ifo Ogun State Nigeria

Biodiesel is an alternative fuel to replace fossil- based diesel fuel. It has fuel properties similar to diesel which are generally determined experimentally. The experimental determination of various properties of biodiesel is costly, time consuming and a tedious process. To solve these problems, artificial neural network （ANN） has been considered as a vital tool for estimating the fuel properties of biodiesel, especially from its fatty acid （FA） composition. In this study, four ANNs have been designed and trained to predict the cetane number （CN）, flash point （FP）, kinematic viscosity （KV） and density of biodiesel using ANN with logsig and purelin transfer functions in the hidden layer of all the networks. The five most prevalent FAs from 55 feedstocks found in the literature utilized as the input parameters for the model are palmitic, stearic, oleic, linoleic and linolenie acids except for density network with a sixth parameter （temperature）. Other FAs that are present in the biodiesels have been considered based on the number of carbon atom chains and the level of saturation. From this study, the prediction accuracy and the average absolute deviation of the networks are CN （96.69%; 1.637%）, KV （95.80%; 1.638%）, FP （99.07%; 0.997%） and density （99.40%; 0.101%）. These values are reasonably better compared to previous studies on empirical correlations and ANN predictions of these fuel properties found in literature. Hence, the present study demonstrates the ability of ANN model to predict fuel properties of biodiesel with high accuracy.

关键词： biodiesel fuel properties artificial neuralnetwork fatty acid prediction

Petrology of lherzolite xenoliths of HosséréSédévolcano(adamawa plateau,Ngaoundéréarea,Cameroon)

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地球化学学报(英文) 2023年第5期42卷 817-831页

作者： O.F.Nkouandou J.M.Bardintzeff Fagny Mefire Njankouo Ndassa A.A.Sahabo H.adama Department of Earth Sciences Faculty of SciencesUniversity of NgaoundereP.O.Box.454NgaoundereCameroon Univ Paris-Saclay Sciences de la TerreVolcanologie-PlanetologieUMR CNRS 8148 GEOPSBat.50491405 OrsayFrance Laboratoire de volcanologie Institut de Recherches Geologique et Minie`reB.P.370BueaCameroon

Numerous mantle xenoliths 6–12 cm in size and sub-angular to rounded in shape occur within Mio-Pliocene basanite lavas of the monogenic volcano of HosséréSédé in the adamawa *** of spinel lherzolite exhibit protogranular,equigranular or porphyroclastic *** chemical analyses show that olivine is highly magnesian(Fo_(88-90)),clinopyroxene crystals are diopside and augite(Wo_(41.6–49.6)En_(45.3–53.7)Fs_(4.2–6.2)),orthopyroxene crystals are enstatite(Wo 1.4–1.5 En_(88.6–89.0)Fs_(9.6–9.9))and spinel crystals are mainly Al-spinel associ-ated to minor *** temperatures and pressures through empirical formulas show that HosséréSédé noliths have equilibrated between 1085 and 1204℃and 1.08 to 1.57 GPa,corresponding to sampling depths of 36 and 52 *** petrographical and mineral chemistry of HosséréSédénoliths evidences the com-plex nature and composition of the subcontinental lithosphere under the adamawa *** may involve a probable uplift of the whole area after a limited exten-sional event,possible metasomatism through melt infiltration during shearing of the lithospheric mantle along the Pan African strike-slip fault system.

关键词： Cameroon adamawa HosséréSédé Subcontinental lithosphere Xenolith Peridotite Lherzolite

Molecular Epidemiology of High-Risk Human Papilloma Virus Infection in Sexually Active Women at Bobo-Dioulasso University Teaching Hospital

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Open Journal of Obstetrics and Gynecology 2019年第8期9卷 1178-1188页

作者： Souleymane Ouattara Der Adolphe Somé adama dembélé Salif Sanfo Théodorat Zohoncon Abdoul-Karim Ouattara Moussa Bambara Blami Dao Jacque Simporé Université Nazi Boni Bobo-Dioulasso Burkina Faso Laboratoire de Biologie Moléculaire et de Génétique (LABIOGENE) Université de Ouagadougou Université Ouaga I professeur Joseph Ki Zerbo Ouagadougou Burkina Faso CHU Souro Sanou Bobo-Dioulasso Burkina Faso

The objective of this study was to determine the prevalence of HPV-HR genotypes in the population of sexually active women in Bobo-Dioulasso, Burkina Faso. Methods: This study took place at Souro Sanou Teaching Hospital in Bobo-Dioulasso from September to June 2017. A total of 234 women in the gynecological period and also sexually active were enrolled after they gave an individual consent. Swabbing of the endocervical canal was done. From the sample stored at -20°C, the viral DNA was extracted using the “DNA-Sorb-A” kit from SACACE biotechnologies®. Amplification of the PCR of the extracted DNA was made, using the “HPV Genotypes 14 Real-TM Quant” V67-100 FRT kit. Data were analyzed with SPSS software version 17.0 and Epi Info 6. Chi-square and Fisher’s tests were used to compare proportions and averages;a link was significant when p 0.05. Results: The mean age was 30.7 ± 7.3 years (median: 30 years);84.5% of them were married, 43.5% had a socio-professional activity and 61% were schooled. A total of 20.6% of women were positive for at least one of the following HPV-HR genotypes: HPV 18, 31, 35, 39, 45, 51, 52, 56, 58, 59, 66, and 68. Genotypes the most frequently found were HPV 52 with 11 cases (17.2%) and 66 with 10 cases (15.6%). Conclusion: Our results show a predominance of HPV-HR genotypes not covered by available vaccines. Mapping genotypes are needed to fully understand viral ecology at the national level. But for instance, the nonavalent vaccine, which has a better coverage of the predominant genotypes, is to be promoted.

关键词： HPV-HR Epidemiology Genotypes Bobo-Dioulasso

Palpebral Reconstruction in a Secondary Ophthalmology Center in Mali: About a Case

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Surgical Science 2023年第2期14卷 97-103页

作者： dembélé adama Sidibe Moro Sidibe Oumar demb.le Ahmadou Poma Hachimi Amadou Abdoulaye Konaté Oumar Diallo Djonny Jonas demb.le Mamadou adama Togo Kadiatou Ba Koita Abdoulaye Nouhoum Coulibaly Cheick Fantamady Tounkara Nouhoum Touré Napo Abdoulaye Régional Hospital of Sikasso Sikasso Mali Alliance for the Development of Community Ophthalmology (ADOC) Bamako Mali Center Médical Jean Marie Cissé Sikasso Mali

Introduction: Significant trauma to the periocular region can seriously damage ocular structures and their adnexa. The eyelids can be damaged during these traumas. The most frequent lesions are lacerations, the surgical treatment of which is generally simple. In some cases, there are complex traumas where there is a loss of tissue, which is difficult to treat. We report the case of a 26-year-old young man, farmer with no medical and surgical history, referred by the odontostomatology and maxillofacial surgery department for burns to the left hemi face by the exhaust pipe of his motorbike which occurred following a public road accident (AVP). Observation: A 26-year-old young man with no medical-surgical history, visual acuity was 5/10 with good mobility of the globe. In collaboration with the maxillofacial surgeon, a graft of the hemi face was performed using a flap from the inner side of the thigh first. In the second time we carried out a recovery by a flap which consisted in taking a supra-superciliary flap and suturing it at the level of the palpebral edges which, in spite of a fragile vitality of the tissues. Conclusion: The reconstruction of the eyelid is a real problem in our service because of the technical platform and the availability of consumables, which limits us in the choice of the operating technique.

关键词： Road Accident Hemi-Face Burn Eyelid Reconstruction

An Application of Machine learning Methods to Detect Mango Varieties

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