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Environmental Assessment and Analysis of Chemical Properties of Drinking Water Using Geo-Spatial Technologies: Examples from Lahore Metropolitan

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Advances in Remote Sensing 2018年第3期7卷 259-275页

作者： Ali Imam Mirza Ali Iqtadar Mirza Tabasam Jamal Syed Shehzad Hassan Muhammad A. Butt Atif Ali Hafsa Batool Rashid Mahmood Attia Naz Azam sohail Imran Saddique Kaukab Sana Alvi Javed Ahmad Safeer Ali Muneeb Aamir Azeem Akhtar Arshad Javed Department of Geography GC University Lahore Pakistan Remote Sensing Group Department of Space Science University of the Punjab Lahore Pakistan

The contamination of drinking water in Pakistan is a serious threat to its citizens. Urbanization leads to an increased demand of drinking water supply that leads to excessive drawdown that further causes lowering of water table. The current WASA (Water and Sanitation Authority) supply network does not fulfill the demand of a growing metropolitan city of Lahore. The drawdown of Lahore is absolutely reliant on Water and Sanitation Authority (WASA) water supply network that causes numerous problems due to inappropriate management of groundwater capital and increased urbanization. This research investigates groundwater qualities: Alkalinity, Arsenic, Calcium, chloride, Total Hardness, Magnesium, Nitrate, pH and Total Dissolved solids using geographic information system (GIS). Residents of high concentrated towns, like Samnabad Town, Allama Iqbal Town, Gulberg, Data Ganj Bakhsh Town, Ravi Town and Wahga town witness cut-down of water supply mainly due to over burden on tube wells. Chemical properties of drinking water show that most of the parameters were within the allowable limits of WHO whereas the pH, and arsenic values are higher than the average. Arsenic is a carcinogenic element which causes cancer and is higher in the drinking water. Finally, this study identifies highly contaminated groundwater zones and makes it convenient to find actual pollutants. Therefore, plans are needed to protect the aquifer.

关键词： Water Contamination Urbanization Geographic Information System (GIS) Chemical Properties Carcinogenic Elements WHO WebGIS RS WASA DNA pH TDS

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Mechanisms mediating the effects of alcohol and HIV anti-retroviral agents on mTORC1,mTORC2 and protein synthesis in myocytes

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World Journal of Biological Chemistry 2012年第6期3卷 110-120页

作者： Ly Q Hong-Brown abid A Kazi Charles H Lang Department of Cellular and Molecular Physiology Penn State College of MedicineHersheyPA 17033United States

Alcoholism and acquired immune deficiency syndrome are associated with severe muscle *** impairment in nitrogen balance arises from increased protein degradation and a decreased rate of protein *** regulation of protein synthesis is a complex process involving alterations in the phosphorylation state and protein-protein interaction of various components of the translation machinery and mammalian target of rapamycin(mTOR) *** review describes mechanisms that regulate protein synthesis in cultured C2C12 myocytes following exposure to either alcohol or human immunodeficiency virus antiretroviral *** attention is given to the upstream regulators of mTOR complexes and the downstream targets which play an important role in *** a better understanding of these molecular mechanisms could have important implications for preventing changes in lean body mass in patients with catabolic conditions or illnesses.

关键词： AMP-activated protein kinase/tuberous sclerosis complex 2/Ras homolog enriched in brain Rag GTPases Phospholipase D Mitogen-activated protein kinase Translation initiation Elongation

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Adaptation of Artificial Intelligence to Predict Concrete Strength

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材料科学与工程（中英文B版） 2013年第10期3卷 661-669页

作者： Ali Laftaa Abbas Suhad Mohammad abid Jinan Laftaa Abbas Civil Engineering Department College of Engineering Diyala University Baqoubah Diyala Iraq

In past, different methods were used to predict the strength of concrete. Artificial intelligence in term of the fuzzy-logic system was used in this study. A new model was proposed and developed for the prediction of concrete compressive strength at different ages. The variables used in the prediction models were from the knowledge of the mix itself, i. e., mix proportion elements. The models providea good estimation of compressive strength and yielded good correlations with the data used in this study. Moreover, the proposed models proved to bea significant tool in predicting compressive strength of different concretes in spite of variations in the results.

关键词：混凝土强度预测模型人工智能混凝土抗压强度模糊逻辑系统模型预测配合比 BEA

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高分子基因载体在胶质瘤治疗中的应用

高分子基因载体在胶质瘤治疗中的应用

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2015年全国高分子学术论文报告会

作者：田华雨高世乾 Yousra Saeed Malik Muhammad abid Sheikh 陈学思中国科学院长春应用化学研究所生态环境高分子材料重点实验室

高分子基因载体在胶质瘤临床治疗中面临的主要问题是其肿瘤靶向性低、血脑屏障穿透能力弱,无法有效携带治疗基因到达脑部胶质瘤发生部位。间充质干细胞（MSCs）具有良好的肿瘤趋向性,我们以聚赖氨酸改性的聚乙烯亚胺高分子聚合物（PEI-... 详细信息

高分子基因载体在胶质瘤临床治疗中面临的主要问题是其肿瘤靶向性低、血脑屏障穿透能力弱,无法有效携带治疗基因到达脑部胶质瘤发生部位。间充质干细胞（MSCs）具有良好的肿瘤趋向性,我们以聚赖氨酸改性的聚乙烯亚胺高分子聚合物（PEI-PLL）作为载体将自杀基因（HSV-TK）瞬转至MSCs,得到了可以高效表达自杀基因蛋白并且保留原有肿瘤细胞归巢特性的MSCs,这种新型干细胞在体内体外胶质瘤模型中可以显著抑制肿瘤细胞增殖能力,并促进肿瘤细胞凋亡。我们将Angiopep-2靶向多肽和聚乙二醇（PEG）接枝到聚乙烯亚胺（PEI）上,开发了具有血脑屏障穿透能力的高分子载体,该载体具有良好的基因转染效率,并且可以携带自杀基因显著杀伤胶质瘤细胞。体内实验结果也表明通过尾静脉注射该载体可以明显促进报告基因在裸鼠脑部的蓄积。高分子基因载体结合肿瘤趋向性间充质干细胞以及血脑屏障靶向多肽的研究有望在胶质瘤临床治疗中获得进一步应用。

关键词：基因载体间充质干细胞基因治疗胶质瘤

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Yield and Profit from New and Old Wheat Varieties Using Certified and Farmer-Saved Seeds

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Journal of Agricultural Science and Technology(B) 2016年第3期6卷 141-150页

作者： Krishna Dev Joshi Attiq Ur Rehrnan Ghulam Ullah Amanullah Baloch Makhdoom Hussain Javed Ahmad Mohammad Ishaq Gulzar Ahmad Nadeem Abroad Syed Haider Abbas Maqsood Qamar Mumtaz Abroad abid Ilyas Dar Badar-uddin Khokhar Muhammad Sajid Akhlaq Hussain Muhammad Imtiaz International Maize and Wheat Improvement Center (CIMMYT) Islamabad 44000 Pakistan Wheat Research Institute Faisalabad 38000 Pakistan Cereal Crops Research Institute Nowshera 24100 Pakistan Barani Agricultural Research Institute Chakwa148800 Pakistan National Agriculture Research Centre lslamabad 44000 Pakistan Engro Fertilizers Limited Lahore 54000 Pakistan Wheat Research Institute Sakrand 67210 Pakistan Pride Seed Company Mardan 23200 Pakistan

Wheat is a strategic crop for food security in Pakistan with predominance of smallholder farmers. Farmer-saved seed （FSS） is used nearly by 75% of farmers for wheat production. Frequent variety or seed replacement is uncommon even among large-scale farmers, and certified seed （CS） is mostly bought to verify the value of new varieties. Replacing old and obsolete varieties by new high yielding disease resistant varieties is key to transferring new genetic gains to farmers. For the first time in Pakistan, on-farm factorial experiments involving seven new and five old wheat varieties and their corresponding CS and FSS were conducted. A total of 49 farmers representing major wheat cropping patterns throughout the country participated in these trials in the 2014 and 2015 wheat growing seasons. Analysis of variance revealed that there was highly significant difference between wheat varieties and between seed classes. New variety ＋ CS gave 33.8% more grain yield as well as higher marginal return over farmers＇ variety ＋ FSS. Grain yield and returns from new variety ＋ FSS and farmers＇ variety ＋ CS were at par. Scientific knowledge generated in this research demonstrated that use of CS ＆new wheat varieties is best option, while growing new varieties with FSS is a second choice for the advantages accruing from their built-in genetic traits of economic importance over growing CS of old and obsolete varieties. Having more flexible seed system will help accelerate the delivery of new genetic gains to farmers＇ fields.

关键词： Certified seed farmer-saved seed variety and seed replacement smallholder farmers yield return varietal popularization.

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巴基斯坦棉花主要害虫及其综合治理

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植物保护 2023年第1期49卷 82-88页

作者：阿比德·阿里王巧杨龙臧红岩吕昭智费萨拉巴德农业大学昆虫学系巴基斯坦旁遮普省费萨拉巴德38040 沈阳师范大学生命科学学院沈阳110000 中国农业科学院植物保护研究所植物病虫害生物学国家重点实验室北京100193 兰州大学政治与国际关系学院兰州730000 青岛农业大学植物医学学院青岛266109

棉花是巴基斯坦重要的经济作物,棉花产品出口是该国外汇收入的主要来源。在过去10年中巴基斯坦棉花种植面积大幅减少,棉花产量也从2011年的261万t下降至2021年的154万t。烟粉虱Bemisia tabaci及其传播的棉花曲叶病和棉红铃虫Pectinophor... 详细信息

棉花是巴基斯坦重要的经济作物,棉花产品出口是该国外汇收入的主要来源。在过去10年中巴基斯坦棉花种植面积大幅减少,棉花产量也从2011年的261万t下降至2021年的154万t。烟粉虱Bemisia tabaci及其传播的棉花曲叶病和棉红铃虫Pectinophora gossypiella等有害生物危害是棉花产量下降的主要原因之一。目前,棉花害虫的防治主要依靠背负式喷雾器或机车式喷雾器喷施杀虫剂,无人机施药的政策及大规模推广应用尚处于起始阶段。害虫对杀虫剂抗性上升是目前害虫治理的主要问题。由于信德省和旁遮普省等传统植棉区棉花害虫发生比较严重,巴基斯坦政府计划在俾路支省和开伯尔-普赫图赫瓦省扩大棉花种植面积。为了恢复棉花的生产,政府制定了一系列计划来提高害虫综合治理水平,如研发生物杀虫剂、转基因品种等。针对当前棉花生产过程中所面临的虫害问题,未来应更新害虫治理策略,加强对农业部门技术人员的培训,为巴基斯坦棉花的可持续生产提供技术支持。

关键词： Bt棉花棉红铃虫杀虫剂害虫综合治理

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Unusual Presentation of a Large Multi-Septated Cystic Hygroma: A Case Report and Comprehensive Literature Review

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Surgical Science 2023年第7期14卷 486-495页

作者： Md. Abir Tazim Chowdhury sohail Ahmed Md. Zulfiqur Haider Niaz Ahmed A. K. M. Fazlul Haque Nasrin Aktar Arup Khan Md. Abdullah-Al-Mahammud Kabir Md. Sifat Uddin Abrar Bin Ahsan Trishna Sarker Md. Khaled Hossain Munama Magdum Department of Cardiothoracic and Vascular Surgery Evercare Hospital Dhaka Dhaka Bangladesh Department of Cardiothoracic Anesthesia Evercare Hospital Dhaka Dhaka Bangladesh Department of Plastic and Reconstructive Surgery Evercare Hospital Dhaka Dhaka Bangladesh Department of Community Medicine Shahid Monsur Ali Medical College Dhaka Bangladesh

Background: Cystic hygromas are primarily found in the cervicofacial, thoracic, and abdominal regions, with limited occurrences in other areas. Despite existing literature on this condition, comprehensive descriptions and MRI findings of cystic hygromas in the extremities are rare. Aim: This case report aims to present a unique instance of a cystic hygroma in the left thigh. The objective is to provide detailed insights into the characteristics of this atypical presentation. Case Presentation: The case involves a 2-year-10 month-old girl with a cystic hygroma in her left thigh. The report includes a comprehensive description of the lesion’s clinical features and diagnostic evaluation, emphasizing the MRI findings to enhance understanding of this rare occurrence. Conclusion: This case report highlights the rarity of cystic hygromas outside the cervicofacial, thoracic, and abdominal regions, explicitly focusing on the occurrence in the left thigh. By presenting detailed insights into the clinical features, MRI findings, histopathological findings, and the surgical approach employed, this report contributes to the existing knowledge on this condition in atypical locations and informs future treatment strategies.

关键词： Cystic Hygroma Lymphangioma Multi-Septated Cystic Hygroma Unusual Presentation Vascular Tumors Benign Soft Tissue Tumors

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Myosin X is involved in N-cadherin-mediated neuronal radial migration

Myosin X is involved in N-cadherin-mediated neuronal radial ...

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中国神经科学学会第十届全国学术会议

作者： Ming-Ming Lai Ye Guo Xing-Da Ju Dong-Dong Zhao Wen-Qiang Fan Hua-Li Yu Jian-Hua Zhang Muhammad abid Sheikh Yousra Saeed Malik Wen-Cheng Xiong Xiao-Juan Zhu Key Laboratory of Molecular Epigenetics Ministry of Education and Institute of Cytology and GeneticsNortheast Normal University Department of Neurology Medical College of Georgia

Myosin X（MyolO）,an uncharacteristic member of the myosin family,is an important regulator of cytoskeleton that modulates cell motihties in many different cellular *** research has established that MyolO is also required for axon outgrowth and neuronal morphological transition in the developing cerebral cortex,but the mechanism is still largely ***,we provide evidence for the involvement of MyolO in N-cadherin mediated cell adhesion and its participation in the neuronal *** show that MyolO is co-localized with N-cadherin at the cell *** and glutathion-S-transferase（GST）-pulldown assays confirm that Myol0 interacts with N-cadherin cytoplasmic domain through a band 4.1-ezrin-radixin-moesin（FERM） *** of Myo10 decreases the surface-associated fraction of N-cadherin and impairs the N-cadherin-mediated neuron ***,it affects the neuron-glial interaction and disturbs neuronal migration in vivo,and some neurons exhibit miss-oriented guiding processes in the radial migration ***,N-cadherin can partially rescue the migration deficiency caused by *** results suggest that Myol0 plays a role in the regulation of N-cadherin-mediated adhesion during neuronal migration in cortical development.

关键词： cortical radial migration cell adhesion in utero electroporation Myosin X N-cadherin

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Is it time to replace propranolol with carvedilol for portal hypertension?

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世界胃肠内镜杂志：英文版（电子版） 2015年第5期7卷 532-539页

作者： Shahab abid Saadat Ali Muhammad Asif Baig Anam Akbar Waheed Section of Gastroenterology Department of Medicine Aga Khan University

Beta-adrenergic receptor antagonists(β-blockers) have been well established for use in portal hypertension for more than three decades. Different Non-selective β-blockers like propranolol, nadolol, timolol, atenolol, metoprolol and carvedilol have been in clinical practice in patients with cirrhosis. Carvedilol has proven 2-4 times more potent than propranolol as a beta-receptor blocker in trials conducted testing its efficacy for heart failure. Whether the same effect extends to its potency in the reduction of portal venous pressures is a topic of on-going debate. The aim of this review is to compare the hemodynamic and clinical effects of carvedilol with propranolol, and attempt assess whether carvedilol can be used instead of propranolol in patients with cirrhosis. Carvedilol is a promising agent among the beta blockers of recent time that has shown significant effects in portal hypertension hemodynamics. It has also demonstrated an effective profile in its clinical application specifically for the prevention of variceal bleeding. Carvedilol has more potent desired physiological effects when compared to Propranolol. However, it is uncertain at the present juncture whether the improvement in hemodynamics also translates into a decreased rate of disease progression and complications when compared to propranolol. Currently Carvedilol shows promise as a therapy for portal hypertension but more clinical trials need to be carried out before we can consider it as a superior option and a replacement for propranolol.

关键词： Portal hypertension Chronic liver disease Non-selective beta-blockers Propranolol Carvedilol

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3-(Tetrazol-5-yl)-2-imino-coumarins Derivatives:Synthesis, Characterization, and Evaluation on Tumor Cell Lines

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International Journal of Organic Chemistry（有机化学国际期刊） 2021年第1期

作者： Ali Bouattour Mehdi Fakhfakh Souhir abid El-Gharbi Majdi abid Ludovic Paquin Rémy Le Guevel Thierry Charlier Houcine Ammar Jean-Pierre Bazureau

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