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Improved Manta Ray Foraging Optimizer-based SVM for Feature Selection Problems:A Medical Case Study

Journal of Bionic Engineering 2024年第1期21卷 409-425页

作者： Adel Got Djaafar Zouache Abdelouahab Moussaoui Laith Abualigah ahmed alsayat Faculty of informatics University of Science and Technology Houari BoumedieneAlgiersAlgeria LRIA Laboratory University of Science and Technology Houari BoumedieneAlgiersAlgeria Computer Science Department University of Mohamed El Bachir El IbrahimiBordj Bou ArreridjAlgeria Computer Science Department University of Ferhat AbbasSetifAlgeria Computer Science Department Prince Hussein Bin Abdullah Faculty for Information TechnologyAl al-Bayt UniversityMafraq 25113Jordan Department of Computer Science College of Computer and Information SciencesJouf UniversityJoufSaudi Arabia Department of Electrical and Computer Engineering Lebanese American University13-5053ByblosLebanon Hourani Center for Applied Scientific Research Al-Ahliyya Amman UniversityAmman 19328Jordan MEU Research Unit Middle East UniversityAmman 11831Jordan Applied science research center Applied science private universityAmman 11931Jordan School of Computer Sciences Universiti Sains Malaysia11800 PenangMalaysia School of Engineering and Technology Sunway University Malaysia27500 Petaling JayaMalaysia

Support Vector Machine(SVM)has become one of the traditional machine learning algorithms the most used in prediction and classification ***,its behavior strongly depends on some parameters,making tuning these parameters a sensitive step to maintain a good *** the other hand,and as any other classifier,the performance of SVM is also affected by the input set of features used to build the learning model,which makes the selection of relevant features an important task not only to preserve a good classification accuracy but also to reduce the dimensionality of *** this paper,the MRFO+SVM algorithm is introduced by investigating the recent manta ray foraging optimizer to fine-tune the SVM parameters and identify the optimal feature subset *** proposed approach is validated and compared with four SVM-based algorithms over eight benchmarking ***,it is applied to a disease Covid-19 *** experimental results show the high ability of the proposed algorithm to find the appropriate SVM’s parameters,and its acceptable performance to deal with feature selection problem.

关键词： Support vector machine Parameters tuning Feature selection Bioinspired algorithms Manta ray foraging optimizer

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Flavone improves liver damage in nicotine-exposed rats via the Nrf2/HO-1 pathway

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Asian Pacific Journal of Tropical Biomedicine 2024年第8期14卷 341-349页

作者： Nora A.Elsayed Fatma SM Moawed Esraa SA ahmed ahmed Hammad Omayma AR Abo-Zaid Biochemistry and Molecular Biology Department Faculty of Vet.Med.Benha UniversityBenha cityEgypt Health Radiation Research National Center for Radiation Research and TechnologyEgyptian Atomic Energy AuthorityCairoEgypt Radiation Biology Department National Center for Radiation Research and TechnologyEgyptian Atomic Energy AuthorityCairoEgypt

Objective:To assess the hepatoprotective effects of flavone on nicotine-induced liver ***:Thirty-six rats were allocated into six groups:the control group,the nicotine group,the flavone alone groups(10 and 25 mg/kg/body weight),and the nicotine groups treated with flavone(10 and 25 mg/kg/body weight).Liver function,oxidative stress,Nrf2 pathway(HO-1,Nrf2,and Keap-1),and inflammatory markers(IL-17,TNF-α,and NF-κB)were ***,a histopathological examination of liver tissues was ***:Nicotine increased liver damage,inflammation,and oxidative ***,flavone suppressed nicotine-induced liver enzymes,oxidative stress,and inflammation,as manifested by increased antioxidants and decreased malondialdehyde level,liver enzymatic activities,and inflammatory ***(10 and 25 mg/kg/body weight)also reduced the level of Keap-1 and increased HO-1 and Nrf2 levels in the liver of nicotine-exposed ***:Flavone has hepatoprotective properties and may slow the progression of liver injury by reducing oxidative stress,liver enzymes,and inflammation possibly via the Nrf2 pathway.

关键词： Flavone Nicotine Liver Nrf2 HO-1 NF-κB

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Evaluation of hybrid closed-loop insulin delivery system in type 1 diabetes in real-world clinical practice:One-year observational study

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World Journal of Diabetes 2024年第3期15卷 455-462页

作者： ahmed Eldib Shilton Dhaver Karim Kibaa Astrid Atakov-Castillo Tareq Salah Marwa al-Badri Abdelrahman Khater Ryan McCarragher Omnia Elenani Elena Toschi Osama Hamdy Department of Clinical Behavioral&Outcomes ResearchJoslin Diabetes CenterBostonMA 02215United States Department of Medicine Harvard Medical SchoolBostonMA 02115United States

BACKGROUND In 2016,the Food and Drug Administration approved the first hybrid closed-loop(HCL)insulin delivery system for adults with type 1 diabetes(T1D).There is limited information on the impact of using HCL systems on patient-reported outcomes(PROs)in patients with T1D in real-world clinical *** this independent study,we evaluated glycemic parameters and PROs over one year of continuous use of Medtronic’s 670G HCL in real-world clinical *** To assess the effects of hybrid closed loop system on glycemic control and quality of life in adults with *** We evaluated 71 patients with T1D(mean age:45.5±12.1 years;59%females;body weight:83.8±18.7 kg,body mass index:28.7±5.6 kg/m2,A1C:7.6%±0.8%)who were treated with HCL at Joslin Clinic from 2017 to *** measured A1C and percent of glucose time-in-range(%TIR)at baseline and 12 *** measured percent time in auto mode(%TiAM)for the last two weeks preceding the final visit and assessed PROs through several validated quality-of-life surveys related to general health and diabetes *** At 12 mo,A1C decreased by 0.3%±0.1%(P=0.001)and%TIR increased by 8.1%±2.5%(P=0.002).The average%TiAM was only 64.3%±32.8%and was not associated with A1C,%TIR or ***,provided at baseline and at the end of the study,showed that the physical functioning submodule of 36Item Short-Form Health Survey increased significantly by 22.9%(Pale decreased significantly by 24.9%(Pal burden submodules of dietary diversity score reduced significantly by-44.7%(P=0.001).Furthermore,analysis of Clarke questionnaire showed no increase in awareness of hypoglycemic ***-5 showed no improvements in subject’s wellbeing among participants after starting the 670G HCL ***,analysis of Pittsburgh Sleep Quality Index showed no difference in sleep quality,sleep latency,or duration o

关键词： Artificial pancreas Continuous blood glucose monitor Type 1 diabetes Hybrid closed-loop insulin delivery Quality of life

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Analysis of Progressively Type-Ⅱ Inverted Generalized Gamma Censored Data and Its Engineering Application

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Computer Modeling in Engineering & Sciences 2024年第10期141卷 459-489页

作者： Refah alotaibi Sanku Dey ahmed Elshahhat Department of Mathematical Sciences College of SciencePrincess Nourah bint Abdulrahman UniversityP.O.Box 84428Riyadh11671Saudi Arabia Department of Statistics St.Anthony’s CollegeShillong793001India Faculty of Technology and Development Zagazig UniversityZagazig44519Egypt

A novel inverted generalized gamma(IGG)distribution,proposed for data modelling with an upside-down bathtub hazard rate,is *** many real-world practical situations,when a researcher wants to conduct a comparative study of the life testing of items based on cost and duration of testing,censoring strategies are frequently *** this point of view,in the presence of censored data compiled from the most well-known progressively Type-Ⅱ censoring technique,this study examines different parameters of the IGG *** a classical point of view,the likelihood and product of spacing estimation methods are *** Fisher information and the deltamethod are used to obtain the approximate confidence intervals for any unknown parametric function of the *** the Bayesian paradigm,the same traditional inferential approaches are used to estimate all unknown ***-Chain with Monte-Carlo steps are considered to approximate all Bayes’*** numerical comparisons are presented to examine the performance of the proposed methodologies using various criteria of ***,using several optimality criteria,the optimumprogressive censoring design is *** highlight how the proposed estimators can be used in practice and to verify the flexibility of the proposed model,we analyze the failure times of twenty mechanical components of a diesel engine.

关键词： Inverted generalized gamma censoring spacing function likelihood Bayesian optimal plan

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Evaluating mechanism of banana pseudo-stem retting using seawater:A cost-effective surface pre-treatment approach

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Journal of Bioresources and Bioproducts 2024年第3期9卷 322-335页

作者： Prince Hotor ahmed H.Hassanin Osbert Akatwijuka Mohamed A.H.Gepreel Mitsuo Yamamoto Yukie Saito ahmed Abdel-Mawgood Egypt-Japan University of Science and Technology Biotechnology ProgramAlexandria GovernorateNew Borg Al Arab 21934Egypt alexandria University Department of Textile EngineeringAlexandria GovernorateBab Sharqi 5424041Egypt Egypt-Japan University of Science and Technology Material Science and EngineeringAlexandria GovernorateNew Borg Al Arab 21934Egypt Graduate School of Agricultural and Life Sciences The University of TokyoBunkyo-KuTokyo 113-8657Japan

Retting has been employed to extract natural fibers from agricultural wastes as a biological and cost-effective approach for *** its global abundance,banana pseudo-stem is a promising agro-waste for lignocellulosic fiber *** this study,fibers were extracted from the pseudo-stems after being pre-treated under four conditions using seawater at room temperature for up to 35 d Bacterial isolation from the fresh seawater sample and screening for ligninolytic ability were *** load as well as laccase and manganese peroxidase enzyme activity profile assay during the retting duration were *** transform infrared(FT-IR)and X-day diffraction(XRD)analyses were also examined for both pre-treated and untreated extracted *** results shows that six out of the eight bacterial isolates had the ability to degrade *** treatments(Raw stem+Raw seawater)and(Autoclaved stem+Raw seawater)recorded the highest viable bacterial load of 9.24×102 and 4.46×102 CFU,respectively,on the 14th day of the retting ***,the highest laccase and manganese peroxidase enzymes activity was recorded for(Raw stem+Raw seawater)and(Autoclaved stem+Raw seawater)treatments in the second to the third *** FT-IR spectra of the pre-treated fibers revealed relative reductions in peaks attributed to polysaccharides and other amorphous substances for all retting *** XRD diffractogram revealed that the crystallinity index(CI)of pre-treated fibers increased in all seawater retting treatment ***,the CI for fibers pre-treated under enzymatic conditions were enhanced even after five *** analysis for selected bacterial isolates showed homology to sequences of Bacillus velezensis,Shewanella sp.L8–5,and Citrobacter amalonaticus and Bacillus subtilis j8 *** these findings,it was suggested that physical,biological,and chemical actions were collectively involved in the seawater retting process of banana ps

关键词： Seawater retting Banana pseudo-stem Natural fiber Enzyme activity Colony forming unit

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Sodium-Glucose Cotransporter-2 Inhibitors: Who, When & How? Guidance for Use from a Multidisciplinary Practical Approach

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International Journal of Clinical Medicine 2024年第9期15卷 413-435页

作者： Khalifa abdullah Magdy ElSharkawy Emad R. Issak ahmed Shawky ElSerafy Samah Idris ahmed Bendary Haytham Reda Badr May Shehata Ashraf Reda Internal Medicine Department Diabetes & Metabolism Unit Faculty of Medicine Alexandria University Alexandria Egypt Nephrology Department Faculty of Medicine Ain Shams University Cairo Egypt Internal Medicine Department Faculty of Medicine Ain Shams University Cairo Egypt Cardiology Department Faculty of Medicine Ain Shams University Cairo Egypt Internal Medicine and Nephrology Department Faculty of Medicine Alexandria University Alexandria Egypt Cardiology Department Faculty of Medicine Benha University Benha Egypt Internal Medicine Department Diabetes and Endocrinology Unit Faculty of Medicine Menoufia University Menoufia Egypt Product Manager Al-Esraa Pharma Cairo Egypt Cardiology Department Faculty of Medicine Menoufia University Menoufia Egypt

Sodium-glucose cotransporter-2 inhibitors (SGLT-2 inhibitors) have transformed diabetes management by targeting renal glucose reabsorption. Designed initially as antidiabetic agents, their ability to lower blood glucose levels independently of insulin is well-documented. Beyond glycemic control, emerging research has unveiled their profound cardiorenal benefits. By inhibiting SGLT-2 protein, these drugs enhance glucose excretion in urine, reducing blood glucose levels. This mechanism has translated into significant cardiovascular and renal protection, establishing SGLT-2 inhibitors as pivotal in managing not only diabetes but also cardiovascular and renal diseases. Recent studies have illuminated the broader therapeutic potential of SGLT-2 inhibitors beyond diabetes. Evidence indicates their efficacy in managing heart failure, chronic kidney disease (CKD), and cardiovascular complications in individuals with or without diabetes. This expanded therapeutic landscape has catalyzed a paradigm shift in SGLT-2 inhibitor use, positioning them as key agents in the cardiorenal metabolic continuum. Moreover, their role in the secondary prevention of cardiovascular events and slowing CKD progression in T2DM patients has garnered considerable attention. This consensus-based review aims to offer practical guidance in an algorithmic approach to primary care healthcare professionals to optimize SGLT-2 inhibitors utilization and maximize their benefits. The review seeks to empower clinicians to effectively manage patients who may benefit from SGLT-2 inhibitor therapy by addressing common initiation barriers and optimizing treatment strategies. Additionally, it aims to raise awareness among primary care physicians regarding the multifaceted benefits of these medications and overcome clinical inertia in their adoption into routine clinical practice.

关键词： Sodium-Glucose Cotransporter-2 Inhibitors Cardiorenal Benefits Therapeutic Potential Cardiovascular Protection Primary Care Optimization

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The impact of chemotherapy-naïve open radical cystectomy delay and perioperative transfusion on the recurrence-free survival: A perioperative parameters-based nomogram

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Asian Journal of Urology 2024年第2期11卷 294-303页

作者： ahmed M.Harraz ahmed Elkarta Mohamed H.Zahran ahmed Mosbah Atallah A.Shaaban Hassan Abol-Enein Urology and Nephrology Center Mansoura UniversityEgypt

Objective: To develop and internally validate a nomogram to predict recurrence-free survival (RFS) including the time to radical cystectomy (RC) and perioperative blood transfusion (PBT) as potential ***: Patients who underwent open RC and ileal conduit between January 1996 to December 2016 were split into developing (n=948) and validating (n=237) cohorts. The time to radical cystectomy (TTC) was defined as the interval between the onset of symptoms and RC. The regression coefficients of the independent predictors obtained by Cox regression were used to construct the nomogram. Discrimination, validation, and clinical usefulness in the validation cohort were assessed by the area under the curve, the calibration plot, and decision curve ***: In the developing dataset, the 1-, 5-, and 10-year RFS were 83.0%, 47.2%, and 44.4%, respectively. On multivariate analysis, independent predictors were TTC (hazards ratio [HR] 1.07, 95% confidence interval [CI] 1.05-1.08, pal hydronephrosis (HR 1.54, 95% CI 1.21-1.97, palidation dataset were 79.3%, 69.6%, and 76.2%, for 1-, 5-, and 10-year RFS, respectively. Calibration plots showed considerable correspondence between predicted and actual survival probabilities. The decision curve analysis revealed a better net benefit of the ***: A nomogram with good discrimination, validation, and clinical utility was constructed utilizing TTC and PBT in addition to standard pathological criteria.

关键词： Radicalcystectomy Blood transfusion Time to radical cystectomy Survival Nomogram

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Boosted photocatalytic removal of NO using direct Z-scheme UiO-66-NH_(2)/Bi_(2)MoO_(6) nanoflowers heterojunction:mechanism insight and humidity effect

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Rare Metals 2024年第8期43卷 3758-3770页

作者： Jiang-Yu-Shan Liang Hai-Tao Ren Abdelkader Labidi Qiu-Hui Zhu Qi-Bing Dong ahmed A.allam ahmed Rady Chuan-Yi Wang School of Environmental Science and Engineering Shaanxi University of Science and TechnologyXi'an 710021China Zoology Department Faculty of ScienceBeni-Suef UniversityBeni-Suef 6251lEgypt Department of Zoology College of ScienceKing Saud University11451 RiyadhSaudi Arabia

In practical applications,relative humidity in the air is a key factor affecting the photocatalytic removal of NO,which is often overlooked in previous ***,we developed a direct Z-scheme UiO-66-NH_(2)/Bi_(2)MoO_(6)heterojunction with a nanoflower-like structure to systematically investigate the effect of relative humidity on photocatalytic removal of *** optimized heterojunction for the removal efficiency of NO was 71.6%at1.07 mg·m^(-3)NO concentration(relative humidity=10%),and the generation of NO_(2) was only 1.1%.Interestingly,with the increase in relative humidity,it showed a higher inhibition effect on NO_(2),while the removal of NO decreased slightly(8%),which might be attributed to the affinity effect of NO_(2) with water molecules and the competitive adsorption of H_(2)O and NO on the surface of the heterojunction ***,the reaction pathways of NO removal at the developed heterojunctions were revealed by in situ DRIFTS *** work provides a novel vision for the development of direct Z-scheme heterojunction photocatalysts to effectively remove NO and inhibit the formation of toxic intermediate NO_(2) under different humidities.

关键词： NO removal Relative humidity Direct Z-scheme Bismuth molybdate Visible-light photocatalysis

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A Novel Fractional Dengue Transmission Model in the Presence of Wolbachia Using Stochastic Based Artificial Neural Network

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Computer Modeling in Engineering & Sciences 2024年第5期139卷 1217-1238页

作者： Zeshan Faiz Iftikhar ahmed Dumitru Baleanu Shumaila Javeed Department of Mathematics COMSATS University IslamabadIslamabad45550Pakistan Department of Mathematics Cankaya UniversityAnkara06790Turkey Institute of Space Sciences Magurele-Bucharest077125Romania Department of Medical Research China Medical University HospitalChina Medical UniversityTaichung40402Taiwan Department of Computer Science and Mathematics Lebanese American UniversityBeirut135053Lebanon Department of Mathematics Mathematics Research CenterNear East UniversityNicosia/Mersin99138Turkey

The purpose of this research work is to investigate the numerical solutions of the fractional dengue transmission model(FDTM)in the presence of Wolbachia using the stochastic-based Levenberg-Marquardt neural network(LM-NN)*** fractional dengue transmission model(FDTM)consists of 12 *** human population is divided into four compartments;susceptible humans(S_(h)),exposed humans(E_(h)),infectious humans(I_(h)),and recovered humans(R_(h)).Wolbachia-infected and Wolbachia-uninfected mosquito population is also divided into four compartments:aquatic(eggs,larvae,pupae),susceptible,exposed,and *** investigated three different cases of vertical transmission probability(η),namely when Wolbachia-free mosquitoes persist only(η=0.6),when both types of mosquitoes persist(η=0.8),and when Wolbachia-carrying mosquitoes persist only(η=1).The objective of this study is to investigate the effectiveness of Wolbachia in reducing dengue and presenting the numerical results by using the stochastic structure LM-NN approach with 10 hidden layers of neurons for three different cases of the fractional order derivatives(α=0.4,0.6,0.8).LM-NN approach includes a training,validation,and testing procedure to minimize the mean square error(MSE)values using the reference dataset(obtained by solving the model using the Adams-Bashforth-Moulton method(ABM).The distribution of data is 80% data for training,10% for validation,and,10% for testing purpose)results.A comprehensive investigation is accessible to observe the competence,precision,capacity,and efficiency of the suggested LM-NN approach by executing the MSE,state transitions findings,and regression *** effectiveness of the LM-NN approach for solving the FDTM is demonstrated by the overlap of the findings with trustworthy measures,which achieves a precision of up to 10^(-4).

关键词： Wolbachia dengue neural network vertical transmission mean square error Levenberg-Marquardt

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Caching Strategies in NDN Based Wireless Ad Hoc Network:A Survey

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Computers, Materials & Continua 2024年第7期80卷 61-103页

作者： ahmed Khalid Rana Asif Rehman Byung-Seo Kim Department of Computer Science FAST School of ComputingNational University of Computer and Emerging SciencesLahore54000Pakistan Department of Software and Communications Engineering Hongik UniversitySejong City30016Republic of Korea

Wireless Ad Hoc Networks consist of devices that are wirelessly *** Ad Hoc Networks(MANETs),Internet of Things(IoT),and Vehicular Ad Hoc Networks(VANETs)are the main domains of wireless ad hoc *** is used in wireless ad hoc *** is based on Transmission Control Protocol(TCP)/Internet Protocol(IP)network where clients and servers interact with each other with the help of IP in a pre-defined *** fetches data from a fixed *** redundancy,mobility,and location dependency are the main issues of the IP network *** these factors result in poor performance of wireless ad hoc *** main disadvantage of IP is that,it does not provide in-network ***,there is a need to move towards a new network that overcomes these *** Data Network(NDN)is a network that overcomes these *** is a project of Information-centric Network(ICN).NDN provides in-network caching which helps in fast response to user *** NDN in wireless ad hoc network provides many benefits such as caching,mobility,scalability,security,and *** considering the certainty,in this survey paper,we present a comprehensive survey on Caching Strategies in NDN-based Wireless *** cachingmechanism-based results are also *** the last,we also shed light on the challenges and future directions of this promising field to provide a clear understanding of what caching-related problems exist in NDN-based wireless ad hoc networks.

关键词： Content centric network Internet of Things mobile ad hoc network named data network vehicular ad hoc network

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