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Primary gastroduodenal tuberculosis presenting as gastric outlet obstruction:A case report and review of literature

World Journal of Clinical Cases 2024年第8期12卷 1536-1543页

作者： Abdihamid mohamed Ali Yahye Garad mohamed Abdirahman Ahmed Mohamud abdulkadir nor mohamed mohamed Rage Ahmed Ismail Mohamud Abdullahi Tuba Saydam Department of General Surgery Mogadishu Somali Turkey Recep Tayyip Erdogan Training and Research HospitalMogadishu 2526Somalia Department of Radiology Mogadishu Somali TurkeyTraining and Research HospitalMogadishu 2526Somalia Department of Pathology Mogadishu Somali Turkey Recep Tayyip Erdogan Training and Research HospitalMogadishu 2526Somalia

BACKGROUND Mycobacterium tuberculosis(TB)is the causative agent of TB,a chronic granulo-matous *** disease is prevalent in low-income countries,posing a significant global health *** TB is one of the three *** disease can mimic other intra-abdominal conditions,leading to delayed diagnosis owing to the absence of specific *** gastric outlet obs-truction(GOO)remains a frequent complication,its incidence has declined with the advent of proton pump inhibitors and Helicobacter pylori eradication *** TB can cause upper gastrointestinal hemorrhage,obstruction,and malignancy-like *** SUMMARY A 23-year-old male presented with recurrent epigastric pain,distension,nausea,vomiting,and weight loss,prompting a referral to a gastroenterologist *** examination revealed distorted gastric mucosa and signs of chronic ***,treatment was interrupted,possibly owing to vomiting or comorbidities such as human immunodeficiency virus infection or *** surgical intervention revealed a dilated stomach and diffuse thickening of the duodenal *** revealed gastric wall effacement with *** Primary gastric TB is rare,frequently leading to *** its rarity,suspicions should be promptly raised when encountering relevant symptoms,often requiring surgical intervention for diagnosis and treatment.

关键词： Tuberculosis Gastrointestinal tuberculosis Gastric outlet obstruction Gastroduodenal tuberculosis Case report

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Examining the Types and Consequences of Female Genital Mutilation in Somalia: A Cross-Sectional Study on the Burden and Impact of Acute and Long-Term Complications

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Open Journal of Obstetrics and Gynecology 2024年第9期14卷 1322-1334页

作者： Rahma Yusuf Haji Mohamud Nur Adam mohamed mohamed Yaqub Hassan Khadija Yusuf Ali Marian Muse Osman Amal nor Ali Ifrah Adan Hilowle Iftin mohamed Osman mohamed Farah Yusuf Mohamud Department of Nursing Mogadishu Somali Turkiye Recep Tayyip Erdogan Training and Research Hospital Mogadishu Somalia Department of Psychiatry and Behavioral Sciences Mogadishu Somali Turkiye Recep Tayyip Erdogan Training and Research Hospital Mogadishu Somalia Department of Pediatric Mogadishu Somali Turkiye Recep Tayyip Erdogan Training and Research Hospital Mogadishu Somalia Department of Obstetrics and Gynecology Mogadishu Somali Turkiye Recep Tayyip Erdogan Training and Research Hospital Mogadishu Somalia Research Department National Institute of Health Mogadishu Somalia Department of Pulmonology Mogadishu Somali Turkiye Recep Tayyip Erdogan Training and Research Hospital Mogadishu Somalia Department of Emergency Medicine Mogadishu Somali Turkiye Recep Tayyip Erdogan Training and Research Hospital Mogadishu Somalia

Background: In Africa, female genital mutilation (FGM) is a widespread and harmful practice, with Somalia having the highest incidence at 98%. This practice has severe and long-lasting physical and mental health consequences. The aim of the study was to evaluate the different types of FGM;immediate and long-term complications associated with the practice, and identify factors related to its prevalence. Method: In a one-year cross-sectional hospital-based study, data were collected from females aged 18 - 50 with a history of FGM. Face-to-face semi-structured questionnaires were used for data collection. Data analysis was performed using SPSS version 26, utilizing univariate and bivariate analyses to identify correlations between variables, which were presented in tables. Results: In a study involving 255 female participants, 65.5% were between 18 and 30 years old. The majority (82.7%) were married, while 47.1% were illiterate. FGM cases were more prevalent in rural areas (61.6%). Among the participants, 45.1% were employed. Type 3 FGM was the most common (44.3%), followed by Type 2 (32.2%) and Type 1 (23.9%). In terms of short-term complications experienced by circumcised women, the most common were bleeding, reported by 29.8% of participants, followed by infection (25.1%), and urinary retention (19.2%). Among the long-term complications observed, recurrent vaginal infections were the most prevalent, affecting 29.8% of the surveyed females. This was episiotomy during delivery (22.3%) and genital scarring (10.2%). Conclusion: The study reveals that Type 3 FGM is highly prevalent among the surveyed females, contributing to an increased risk of recurrent vaginal infections, prolonged second stage of labor, higher likelihood of episiotomy during delivery, and genital scarring. These findings emphasize the urgent need for effective preventive strategies and implementation from both international and local organizations to eliminate the harmful practice of FGM.

关键词： Female Genital Mutilation Women Obstetrics and Gynecology Somalia

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Spatial distribution and structure of benthic polychaete communities of Essaouira intertidal rocky shores(Atlantic coast of Morocco)

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Journal of Oceanology and Limnology 2020年第1期38卷 143-155页

作者： CHOUIKH nor-eddine GILLET Patrick LANGSTON WJ CHEGGOUR mohamed MAAROUF Abdelmalek MOUABAD Abdelfattah Laboratory“Aliments Environnement et santé”Faculty of Sciences and TechnicsB.P.549Cadi Ayyad UniversityMarrakech 40000Morocco Mer Molécules Santé Department of Biology EnvironmentFaculty of Sciences UCOAngers 49008France Marine Biological Association the LaboratoryCitadel HillPlymouth PL12PBUnited Kingdom Department of Biology Ecole Normale SupérieureB.P.2400Cadi Ayyad UniversityMarrakech 40000Morocco

Polychaetes are one of the most important groups ofmacrobenthic organisms in coastal and marine environments,in terms of diversity and abundance,and play an important role in the functioning of *** study aims to describe the structure and spatial distribution ofpolychaete communities along Essaouira's rocky shoreline(Atlantic coast of Morocco)in relation to the major environmental variables such as granulometry,salinity,temperature,pH,and intertidal *** sites from these intertidal rocky shores were sampled using a quadrat method during the summer 2016.A total of 4435 individuals belonging to 34 taxa were *** the families,Sabellaridae(24%)and Nereididae(23%)were ranked first in terms of abundance of *** alveolata(24%)and Perinereis cultrifera(13%)were the dominant ***(H')values varied from 2.28 to ***'s index(J')varied between 0.62 and *** was essentially due to the low dominance of few *** analysis was used to characterise Essaouira's rocky shores on the basis of benthic polychaete *** analysis confirmed the presence of three distinct *** to canonical correspondence analysis,the structure and distribution of faunal assemblages of benthic polychaetes was mainly related to topographical complexity,water temperature,hydrodynamic conditions and *** conclude that these rocky shores show typically high benthic polychaete diversity compared to the taxonomic list of other rocky *** addition,these results constitute a baseline data for the development of a sustainable network for long-term monitoring of benthic polychaete community changes due to ecological factor influences and anthropogenic activity impacts.

关键词： polychaetes taxonomic diversity Essaouira rocky shore faunal assemblage

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The protective effects of procyanidin C-1 on bisphenol A-induced testicular dysfunction in aged mice

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Food Science and Human Wellness 2022年第4期11卷 965-974页

作者： Mastura Abd Malek Razif Dasiman nor-Ashikin mohamed Noor Khan Sofee mohamed-Akhlak Mohd-Hafi zi Mahmud Maternofetal and Embryo Research Group(MatE) Faculty of MedicineUniversiti Teknologi MARASelangor BranchSungai Buloh Campus47000 Sungai BulohSelangorMalaysia Faculty of Health Sciences Universiti Teknologi MARASelangor BranchPuncak Alam Campus42300 Puncak AlamSelangorMalaysia

The number and quality of sperm are decreased due to bisphenol A(BPA) exposure, an endocrine-disrupting chemical on the male reproductive system, especially in advanced paternal age(APA). Procyanidin C-1(PCY-1), an antioxidant from grape seed(Vitis vinifera L.), has demonstrated anti-viral, anti-melanogenic and immunostimulatory effects. Therefore, this study aims to determine the effects of PCY-1 intervention on sperm parameters, testis morphological changes, serum testosterone, oestradiol, and luteinizing hormone(LH) concentrations and the expression of apoptotic(Bax and Bcl-2) and mitochondria-related(Mfn1 and Opa1) genes in BPA-exposed aged mice. Results revealed that PCY-1 intervention improves aged male fertility in BPA-exposed conditions by decreasing abnormal sperms percentage and increasing spermatogenic cell diameter and epithelial height. PCY-1 also decreased oestradiol, and increased LH and testosterone levels. The gene expression of Bax was significantly down-regulated by PCY-1 intervention. In contrast, Bcl-2 was substantially up-regulated. Expression of Mfn1 and Opa1 genes were also significantly up-regulated in the PCY intervention group. Hence, it is demonstrated that PCY-1 was able to mitigate the adverse effects of BPA on reproductive parameters of aged mice. Collectively, we postulated that PCY-1 has a potential role in protecting the ageing male reproductive system against the damaging impacts of BPA.

关键词： Apoptosis Bisphenol A Procyanidin Mitochondrial dynamics Testis

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Fenofibrate for the prevention of progression of non-proliferative diabetic retinopathy:review,consensus recommendations and guidance for clinical practice

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International Journal of Ophthalmology(English edition) 2022年第12期15卷 2001-2008页

作者： nor Fariza Ngah nor Asiah Muhamad Roslin Azni Abdul Aziz Shelina Oli mohamed nor Azita Ahmad Tarmizi Azian Adnan Zalifah Zakiah Asnir Zanariah Hussein Hui Foo Siew Masni mohamed Noor Aliza Lodz Vijayamala Valayatham Institute for Clinical Research National Institutes of HealthSetia AlamSelangor 40790Malaysia Hospital Shah Alam Selangor 40000Malaysia Sector for Evidence-Based Healthcare National Institutes of HealthSetia AlamSelangor 40790Malaysia Hospital Kuala Lumpur Wilayah Persekutuan Kuala Lumpur 50586Malaysia Hospital Selayang Selangor 68100Malaysia Hospital Ampang Selangor 68000Malaysia Hospital Putrajaya Wilayah Persekutuan Putrajaya 62250Malaysia Institute for Public Health National Institutes of HealthSetia AlamSelangor 40790Malaysia

The prevalence of diabetic retinopathy(DR),and associated morbidity is high in the Asia-Pacific *** evidence suggests a potential role for fenofibrate in the prevention of progression of DR,especially in patients with cardiovascular risk,and pre-existing mild-to-moderate *** has also been found to reduce maculopathy,and the need for laser treatment in these *** these benefits of fenofibrate,a group of experts from the fields of endocrinology and ophthalmology convened in May 2017,to discuss on the the mechanism of action,and clinical efficacy of fenofibrate in *** findings from key clinical studies on fenofibrate in DR were reviewed by the experts,and consensus statements were derived to define the role of fenofibrate in the prevention and treatment of *** statements were rated based on the GRADE *** algorithm was also developed for the screening and treatment of DR in patients with type 2 diabetes(T2D),and the place of fenofibrate was defined in the *** expert recommendations,and the algorithm provided in this review will serve as a guide to the clinicians to reconsider the adjunctive use of fenofibrate for preventing the progression of DR in selected T2D patients.

关键词： diabetic retinopathy fenofibrate consensus recommendations

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Glutathione (GSH) improves sperm quality and testicular morphology in streptozotocin-induced diabetic mice

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Asian Journal of Andrology 2021年第3期23卷 281-287页

作者： Fathiah Abdullah mohamed Noor Khan nor-Ashikin Renu Agarwal Yuhaniza Shafinie Kamsani Mastura Abd Malek nor Salmah Bakar Aqila-Akmal Mohammad Kamal Mimi-Sophia Sarbandi nor-Shahida Abdul Rahman Nurul Huda Musa Maternofetal and Embryo Research Group(MatE) Faculty of MedicineUniversiti Teknologi MARASelangor BranchSungai Buloh CampusSungai Buloh 47000SelangorMalaysia Faculty of Applied Sciences Universiti Teknologi MARAPerak BranchTapah CampusTapah Road 35400PerakMalaysia Faculty of Medicine Universiti Teknologi MARASelangor BranchSungai Buloh CampusSungai Buloh 47000SelangorMalaysia School of Medicine International Medical UniversityBukit JalilKuala Lumpur 57000Malaysia Faculty of Health Sciences Universiti Teknologi MARASelangor BranchPuncak Alam CampusBandar Puncak Alam 42300SelangorMalaysia Centre of Foundation Studies Universiti Teknologi MARASelangor BranchDengkil CampusDengkil 43800SelangorMalaysia

Diabetes mellitus(DM)is known to cause reproductive *** men,it has been linked to altered sperm quality and testicular *** stress(OS)plays a pivotal role in the development of DM ***(GSH)is a part of a nonenzymatic antioxidant defense system that protects lipid,protein,and nucleic acids from oxidative ***,the protective effects of exogenous GSH on the male reproductive system have not been comprehensively *** study determined the impact of GSH supplementation in ameliorating the adverse effect of type 1 DM on sperm quality and the seminiferous tubules of diabetic C57BL/6NTac *** at the doses of 15 mg kg^(-1)and 30 mg kg^(-1)was given intraperitoneally to mice weekly for 6 consecutive *** mice were then weighed,euthanized,and had their reproductive organs *** diabetic(D Group)showed significant impairment of sperm quality and testicular histology compared with the nondiabetic(ND Group).Diameters of the seminiferous lumen in diabetic mice treated with 15 mg kg^(-1) GSH(DGSH15)were decreased compared with the D *** motility was also significantly increased in the DGSH15 *** in testicular morphology might be an early indication of the protective roles played by the exogenous GSH in protecting sperm quality from effects of untreated type 1 DM or diabetic *** investigation using different doses and different routes of GSH is necessary to confirm this suggestion.

关键词： diabetes mellitus glutathione mice sperm quality testis histology

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Toxic effects of Litsea elliptica Blume essential oil on red blood cells of Sprague-Dawley rats

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2009年第11期10卷 813-819页

作者： Izatus Shima TAIB Siti Balkis BUDIN Seri Maseran SITI nor AIN Jamaludin mohamed Santhana Raj LOUIS Srijit DAS Sulaiman SALLEHUDIN nor Fadilah RAJAB Othman HIDAYATULFATHI Department of Biomedical Sciences Faculty of Allied Health SciencesUniversiti Kebangsaan MalaysiaJalan Raja Muda Abdul Aziz50300 Kuala LumpurMalaysia Unit of Electron Microscope Institute for Medical ResearchJalan Pahang50588 Kuala LumpurMalaysia Department of Anatomy Universiti Kebangsaan MalaysiaJalan Raja Muda Abdul Aziz50300 Kuala LumpurMalaysia

Litsea elliptica Blume leaves have been traditionally used as medicinal herbs because of its antimutagenicity,chemopreventative and insecticidal properties. In this study,the toxic effects of L. elliptica essential oil against Sprague-Dawley rat’s red blood cells (RBCs) were evaluated. L. elliptica essential oil was given by oral gavage 5 times per week for 3 treated groups in the doses of 125,250,and 500 mg/(kg body weight),respectively,and the control group received distilled water. Full blood count,RBC osmotic fragility,RBC morphological changes,and RBC membrane lipid were analyzed 28 d after the treatment. Although L. elliptica essential oil administration had significantly different effects on hemoglobin (Hb),mean cell hemoglobin concentration (MCHC),mean cell volume (MCV),and mean cell hemoglobin (MCH) in the experimental groups as compared to the control group (Pnormal range. L. elliptica induced morphological changes of RBC into the form of echinocyte. The percentage of echinocyte increased significantly among the treated groups in a dose-response manner (P0.05). It is concluded that structural changes in the RBC membrane due to L. elliptica essential oil administration did not cause severe membrane damage.

关键词： Litsea elliptica Toxicity Red blood cells Morphology Cell membrane Echinocyte

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Influence of urban air pollution on the population in the Klang Valley,Malaysia:a spatial approach

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Ecological Processes 2022年第1期11卷 126-141页

作者： Siti Haslina Mohd Shafie Mastura Mahmud Suzani Mohamad nor Lita Fadilah Rameli Ramdzani Abdullah Ahmad Fariz mohamed Centre for Research in Development Social and Environment(SEEDS)Faculty of Social Sciences and HumanitiesUniversiti Kebangsaan MalaysiaBangiSelangorMalaysia Department of Environment Faculty of Forestry and Envi-ronmentUniversiti Putra MalaysiaSerdangSelangorMalaysia Institute for Environment and Development(LESTARI) Universiti Kebangsaan MalaysiaBangiSelangorMalaysia.

Background:Urban air pollution resulting from economic growth as well as urbanization impacts the health of *** study aims to examine the spatial distribution of particulate matter(PM_(10))and the risk of exposure for the population in the Klang Valley,an urban conglomeration centred in Kuala Lumpur,***:The inverse distance weighted(IDW)interpolation technique in the ArcGIS platform was used to map the air quality from five air monitoring *** statistics of the Global Moran’s I Spatial Autocorrelation and Optimized Hot Spot Analysis were used to estimate the spatial clustering of PM_(10).The population-weighted exposure level(PWEL)technique was used to calculate the population density susceptible to PM_(10)and the AirQ+model was applied to estimate the proportion of the adult population at risk of chronic bronchitis due to long-term exposure to PM_(10)concentrations in the Klang ***:The highest annual mean PM_(10)concentrations at the Klang station ranged between 80 and 100μg/m^(3)from 2000 to 2009 and exceeded the New Malaysia Ambient Air Quality Standard(NMAAQS)and the World Health Organi-zation Air Quality Guidelines(WHOAQG)levels of 40 and 20μg/m^(3),*** Moran’s I results indicated that the statistically significant clusters of high PM_(10)in Klang present a health risk to the local *** PWEL results showed that levels of PM_(10)in Petaling Jaya exceeded the WHOAQG limits,potentially posing a health risk to the high-density *** AirQ+model found Klang to be a significantly high-risk area for chronic bronchitis among the adult population with 804,240 people(with a relative risk of 1.85)in ***:These high-risk values are due to rapid urbanization and high motor vehicle usage in the Klang Valley and therefore the impact of PM_(10)on the population needs to be *** situation should be taken seriously by the Department of Environment and Kuala Lumpur City Hall in addre

关键词： Population Urban air pollution Spatial distribution PM_(10) Adult chronic bronchitis risk

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Trichomonas vaginalis infection in a low-risk women attended in Obstetrics and Gynaecology Clinic, Universiti Kebangsaan Malaysia Medical Centre

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Asian Pacific Journal of Tropical Biomedicine 2016年第8期6卷 702-705页

作者： norhayati Moktar nor Liyana Ismail Phoy Cheng Chun Mohamad Asyrab Sapie nor Farahin Abdul Kahar Yusof Suboh noraina Abdul Rahim nor Azlin mohamed Ismail Tengku Shahrul Anuar Department of Parasitology and Medical Entomology Universiti Kebangsaan Malaysia Medical Centre Department of Obstetrics and Gynaecology Universiti Kebangsaan Malaysia Medical Centre Department of Medical Laboratory Technology Faculty of Health Sciences Universiti Teknologi MARAPuncak Alam Campus

Objective: To investigate the presence of trichomoniasis among women attending the Obstetrics and Gynaecology Clinic, Universiti Kebangsaan Malaysia Medical ***: A total of 139 high vaginal swabs were taken from the subjects and sent to the laboratory in Amies gel transport media. The specimens were examined for the presence of Trichomonas vaginalis using wet mount, Giemsa staining and cultured in Diamond's medium. Sociodemographic characteristics and gynaecological complaints were obtained in private using structured questionnaire applied by one ***: The median age was 32 years, with an interquartile interval of 9.96. Most of the subjects were Malays(76.9%) and the remaining were Chinese(15.1%), Indians(2.2%)and other ethnic groups(5.8%). One hundred and thirty eight(99.3%) of the women were married and 98.6% had less than 6 children. More than half(75.5%) of the women's last child birth was less than 6 years ago. Forty seven percent of them were involved in supporting administrative work and 64.7% of the women gave a history of previous or current vaginal ***: The present study reported zero incidence rate of trichomoniasis. The low incidence rate was postulated due to all women who participated in this study were categorized into a low-risk group.

关键词： Trichomoniasis Incidence rate Wet mount Giemsa staining Culture

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Laboratory efficacy of mycoparasitic fungi(Aspergillus tubingensis and Trichoderma harzianum) against tropical bed bugs(Cimex hemipterus)(Hemiptera:Cimicidae)

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Asian Pacific Journal of Tropical Biomedicine 2017年第4期7卷 288-293页

作者： Zulaikha Zahran Nik Mohd Izham mohamed nor Hamady Dieng Tomomitsu Satho Abdul Hafiz Ab Majid Household and Structural Urban Entomology Laboratory Vector Control Research UnitSchool of Biological SciencesUniversiti Sains Malaysia Plant Pathology Laboratory School of Biological SciencesUniversiti Sains Malaysia Institute of Biodiversity and Environmental Conservation Universiti Malaysia Sarawak Department of Microbiology Faculty of Pharmaceutical SciencesFukuoka University

Objective: To test the effectiveness of conidial spore formulations [Aspergillus tubingensis(***) and Trichoderma harzianum(***)] against tropical bed bugs, Cimex ***: Spore formulations were made from two fungal strains, *** and *** bed bugs were exposed to the conidial spores placed soaked onto a fabric cloth for 1 h and the mortality counts were recorded daily until 14 ***: Mean survival times based on Kaplan–Meier survival analysis showed no significant differences between all the concentrations in both the fungal isolates:*** and ***, the evaluation of both the isolates in terms of virulence resulted in low lethal hours in all the concentrations except for the high concentration of ***(LT_(50)= 44.629 h) at the conidial exposure of 1 × 10~6 spores/*** mortality of the bed bugs was observed from Day 6 to Day 12, ranging from 13% to 90% in all three concentrations of *** reference to the *** exposure, the concentration of 1 × 10~4 spores/mL displayed a gradual increase in the percentage mortality of 90 on Day ***: Approaches to the bed bugs treatment should be explored in-depth using a natural biological agent like fungus especially *** to reduce this pest population, in order to replace chemical methods.

关键词： Tropical bed bug Mycoparasitic fungi Aspergillus tubingensis Trichoderma harzianum Bio-control

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