检索结果-南通市图书馆

Enteric neuropathy in diabetes:Implications for gastrointestinal function

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2024年第22期30卷 2852-2865页

作者： mona mohamed Ibrahim.abdalla Department of Human Biology School of MedicineInternational Medical UniversityBukit Jalil 57000Kuala LumpurMalaysia

Diabetes,commonly known for its metabolic effects,also critically affects the enteric nervous system(ENS),which is essential in regulating gastrointestinal(GI)motility,secretion,and *** development of diabetes-induced enteric neuropathy can lead to various GI dysfunctions,such as gastroparesis and irregular bowel habits,primarily due to disruptions in the function of neuronal and glial cells within the ENS,as well as oxidative stress and *** editorial explores the pathophysiological mechanisms underlying the development of enteric neuropathy in diabetic ***,it discusses the latest advances in diagnostic approaches,emphasizing the need for early detection and intervention to mitigate GI complications in diabetic *** editorial also reviews current and emerging therapeutic strategies,focusing on pharmacological treatments,dietary management,and potential neuromodulatory ***,this editorial highlights the necessity of a multidisciplinary approach in managing enteric neuropathy in diabetes,aiming to enhance patient quality of life and address a frequently overlooked complication of this widespread disease.

关键词： Diabetic neuropathy Gastrointestinal Insulin resistance Diabetes Enteric nervous system Enteric neuropathy

Insulin resistance as the molecular link between diabetes and Alzheimer's disease

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Diabetes 2024年第7期15卷 1430-1447页

作者： mona mohamed Ibrahim.abdalla Department of Human Biology School of MedicineInternational Medical UniversityBukit Jalil 57000Kuala LumpurMalaysia

Diabetes mellitus(Dm)and Alzheimer's disease(AD)are two major health concerns that have seen a rising prevalence *** studies have indicated a possible link between Dm and an increased risk of developing ***,while primarily known for its role in regulating blood sugar,also plays a vital role in protecting brain *** resistance(IR),especially prevalent in type 2 diabetes,is believed to play a significant role in AD's *** insulin signalling becomes dysfunctional,it can negatively affect various brain functions,making individuals more susceptible to AD's defining features,such as the buildup of beta-amyloid plaques and tau protein *** research suggests that addressing insulin-related issues might help reduce or even reverse the brain changes linked to *** review aims to explore the relationship between Dm and AD,with a focus on the role of *** also explores the molecular mechanisms by which IR might lead to brain changes and assesses current treatments that target *** IR's role in the connection between Dm and AD offers new possibilities for treatments and highlights the importance of continued research in this interdisciplinary field.

关键词： Alzheimer's disease Insulin resistance Obesity Dementia Diabetes metabolic syndrome

Classified VPN Network Traffic Flow Using Time Related to Artificial Neural Network

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Computers, materials & Continua 2024年第7期80卷 819-841页

作者： Saad abdalla Agaili mohamed Sefer Kurnaz Department of Electrical and Computer Engineering Altinbas UniversityIstanbul34000Turkey

VPNs are vital for safeguarding communication routes in the continually changing cybersecurity ***,increasing network attack complexity and variety require increasingly advanced algorithms to recognize and categorizeVPNnetwork *** present a novelVPNnetwork traffic flowclassificationmethod utilizing Artificial Neural Networks(ANN).This paper aims to provide a reliable system that can identify a virtual private network(VPN)traffic fromintrusion attempts,data exfiltration,and denial-of-service *** compile a broad dataset of labeled VPN traffic flows from various apps and usage ***,we create an ANN architecture that can handle encrypted communication and distinguish benign from dangerous *** effectively process and categorize encrypted packets,the neural network model has input,hidden,and output *** use advanced feature extraction approaches to improve the ANN’s classification accuracy by leveraging network traffic’s statistical and behavioral *** also use cutting-edge optimizationmethods to optimize network characteristics and *** suggested ANN-based categorization method is extensively tested and *** show the model effectively classifies VPN traffic *** also show that our ANN-based technique outperforms other approaches in precision,recall,and F1-score with 98.79%*** study improves VPN security and protects against new *** VPNtraffic flows effectively helps enterprises protect sensitive data,maintain network integrity,and respond quickly to security *** study advances network security and lays the groundwork for ANN-based cybersecurity solutions.

关键词： VPN network traffic flow ANN classification intrusion detection data exfiltration encrypted traffic feature extraction network security

Advancing diabetes management: Exploring pancreatic beta-cell restoration’s potential and challenges

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2024年第40期30卷 4339-4353页

作者： mona mohamed Ibrahim.abdalla Department of Human Biology School of MedicineInternational Medical UniversityBukit Jalil 57000Kuala LumpurMalaysia

Diabetes mellitus,characterized by chronic hyperglycemia due to insulin deficiency or resistance,poses a significant global health *** to its pathogenesis is the dysfunction or loss of pancreatic beta cells,which are res-ponsible for insulin *** advances in beta-cell regeneration research offer promising strategies for diabetes treatment,aiming to restore endogenous insulin production and achieve glycemic *** review explores the physiological basis of beta-cell function,recent scientific advan-cements,and the challenges in translating these findings into clinical *** highlights key developments in stem cell therapy,gene editing technologies,and the identification of novel regenerative *** the potential,the field faces hurdles such as ensuring the safety and long-term efficacy of regen-erative therapies,ethical concerns around stem cell use,and the complexity of beta-cell differentiation and *** review highlights the importance of interdisciplinary collaboration,increased funding,the need for patient-centered approaches and the integration of new treatments into comprehensive care strategies to overcome these *** continued research and collab-oration,beta-cell regeneration holds the potential to revolutionize diabetes care,turning a chronic condition into a manageable or even curable disease.

关键词： Diabetes therapies Beta cell regeneration Regenerative medicine Stem cell therapy Gene editing molecular therapeutics

Ballistic design and testing of a composite armour reinforced by CNTs suitable for armoured vehicles

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Defence Technology（防务技术） 2024年第2期32卷 173-195页

作者： Evangelos Ch.Tsirogiannis Evangelos Daskalakis mohamed H.Hassan abdalla m.Omar Paulo Bartolo EODH SA Research and Development DepartmentLakkoma Chalkidikis63080Greece School of mechanical Aerospace and Civil EngineeringUniversity of ManchesterManchesterM139PLUK Singapore Centre for 3D Printing School of Mechanical and Aerospace EngineeringNanyang Technological University639798Singapore

This paper is investigating the use of composite armour reinforced by nanomaterials, for the protection of light armoured(LAV) and medium armoured military vehicles(mAV), and the interaction between the composite materials and high-performance ballistic projectiles. Four armour materials, consisted of front hybrid fibre reinforced polymer cover layer, ceramic strike-face, fibre reinforced polymer intermediate layer and the metal matrix composite reinforced backplate, were manufactured and assembled by adhesive technology. The proposed laminated protection system is suitable for armoured ground vehicles;however, it could be used as armour on ground, air and naval platforms. The design of the protection system, including material selection and thickness, was elaborated depending on the performance requirements of Level 4 + STANAG 4569 military standard(projectile 14.5 mm × 114 mm API B32) and especially on a design philosophy which is analysed with the specifications. The backplate of this new composite is a hybrid material of metal matrix Composite(mmC) reinforced with carbon nanotubes(CNTs), manufactured with the use of powder metallurgy technique. The composite backplate material was morphologically, mechanically and chemically analysed. Results show that all plates are presenting high mechanical properties and ballistic characteristics, compared to commonly used armour plates. Real military ballistic tests according to AEP-STANAG 4569 were carried out for the total composite armour systems. After the ballistic tests, AA2024-CNT3 showed the best protection results, compared with the other plates(AA2024-CNT1 and AA2024-CNT2), with the projectile being unable to fully penetrate the composite plate.

关键词： Passive armour protection Protective armour Ballistic performance Hybrid composites Vehicle protection

Advancing sandstone reservoir compressibility prediction:A correlation-driven methodology

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Petroleum Research 2024年第2期9卷 273-279页

作者： Tarek Ganat meftah Hrairi Amr Badawy Vahid Khosravi mohammed abdalla Department of Petroleum Chemical Engineering Sultan Qaboos UniversityP.O.Box 50Al-Khod123MuscatOman Department of mechanical and Aerospace Engineering International Islamic University MalaysiaP.O.Box 1050728Kuala LumpurMalaysia Reservoir Engineering Section Petronas Carigali SDN BHDP.O.Box 10500088Kuala LumpurMalaysia Department of Chemical and Petroleum Engineering Faculty of EngineeringTechnologyand Built EnvironmentUCSI University56000Kuala LumpurMalaysia Chemical&Petroleum Engineering United Arab Emirates UniversityP.O.Box No.15551Al AinUAE

This study presents a correlation-based approach for predicting the compressibility of sandstone reservoir *** study proposes a matrix of new empirical equations that significantly improve the precision of measuring the pore volume compressibility,with the most optimal fit of results based on a cubic polynomial *** accuracy of the calculations was validated through comparison with actual data using root mean square method,and the suggested correlations significantly enhance the precise prediction of rock compressibility in sandstone *** this study,the source of data collection is consolidated and unconsolidated sandstone from East Asia offshore ***,variations in compressibility with net overburden pressure over the course of the field's lifespan have been *** results demonstrate the application of regression analysis in establishing a network of linkages between independent and dependent *** proposed correlations for consolidated and unconsolidated sandstones offer a remarkable improvement in the accurate calculation of rock compressibility compared to traditional laboratory procedures,with an average error of 2.5%compared to 5-10%for laboratory *** approach of this study offers a cost-effective and time-efficient alternative to remarkedly enhance the overall performance of sandstone reservoirs in the oil and gas industry.

关键词： Compressibility Consolidated and unconsolidated sandstone Rock properties Rock mechanics

Simulation and structural parameter optimization of rotary blade cutting soil based on SPH method

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Agricultural and Biological Engineering 2024年第3期17卷 82-90页

作者： Xiongye Zhang Xue Hu Lixin Zhang abdalla Noureldin Osman Kheiry College of mechanical and Electrical Engineering Shihezi UniversityShihezi 832000XinjiangChina Bingtuan Energy Development Institute Shihezi UniversityShihezi 832000XinjiangChina Xinjiang Production and Construction Corps Key Laboratory of modern Agricultural machinery Shihezi 832000XinjiangChina Key Laboratory of Northwest Agricultural Equipment Ministry of Agriculture and Rural AffairsShihezi 832000XinjiangChina College of Agricultural Engineering Sudan University of Science and TechnologyKhartoum 999129Sudan

Pre-sowing mechanical tillage in crop fields is a primary task and important aspect of crop *** interaction between the tillage components and the soil plays a crucial role in determining the energy consumption of tillage ***,it is essential to investigate soil-tool interaction mechanisms and optimize tool design for energy savings in soil *** study employed the Smoothed Particle Hydrodynamics(SPH)method to investigate the soil cutting process of a typical rotary *** article describes the principles and modeling process of the SPH method in *** includes the selection of constitutive models,boundary treatments,and particle conversion.A high-precision soil-tool interaction model was established to analyze the deformation zone of the soil,cutting energy,cutting resistance,and soil particle *** simulation experiments and response surface methodology were used to optimize key design parameters of the rotary blade considering both the reduction in cutting power consumption and the impact on the structural performance of the *** optimal parameters were determined as follows:a bending point included angle of 30°,a side cutting edge bending line direction angle of 51°,and a bending angle of 120°.These parameters resulted in a minimum power consumption of 0.181 kW while meeting the required structural ***,experiments were conducted on field rotary tillage,and the measured power consumption showed a deviation of 7.1%from the simulated power *** optimized power consumption was reduced by 9.52%compared to the initial power consumption,validating the accuracy of the simulation process and the effectiveness of energy savings.

关键词： rotary blade Smoothed Particle Hydrodynamics response surface methodology energy consumption optimization

mechanical performance of cold mix asphalt containing cup lump rubber as a sustainable bio-modifier

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Traffic and Transportation Engineering(English Edition) 2024年第3期11卷 424-440页

作者： Syed Abdul Ghafar muhammad Naqiuddin mohd Warid Norhidayah Abdul Hassan Zulfiqar Ali Jattak Ashraf abdalla mohammed Radwan Faculty of Civil Engineering Universiti Teknologi MalaysiaSkudai 81310Malaysia Department of Civil Engineering Balochistan University of Information TechnologyEngineering&Management SciencesQuettaPakistan Department of Civil Engineering Balochistan University of Engineering and TechnologyKhuzdarPakistan Department of Civil Engineering Faculty of EngineeringUniversity of TripoliTripoliLibya

The road construction industry aims to contribute to the protection of already compromised *** mix asphalt(CmA)is a measure initiated by the road industry to protect the environment and preserve *** having additional benefits,CmA has attracted little attention due to its inferior ***'s performance is enhanced using a sustainable binder bio-modifier,natural cup lump rubber(CLR)is one of *** study evaluated the tensile properties,rutting,moisture susceptibility,and adhesion properties of CLR-modified CmA(CmA-CR).The tensile property was enhanced by 26%due to CLR ***-CR had excellent rutting resistance of less than 2 mm rut depth at 10,000 load cycles,showing 70%improvement compared with conventional *** susceptibility evaluation indicated that CmA-CR had tensile strength ratio(TSR)value of 104%,satisfying the minimum 80%requirement of AASHTO *** also retained more than 96%bitumen *** moisture damage resistance was improved by 12%and 10%in terms of TSR and stripping,*** durability results revealed that the CmA-CR mixture prevented higher mass loss,representing 14%improvement compared with conventional CmA.

关键词： Cup lump rubber Cup lump modified cold mix asphalt moisture damage Tensile property Rutting Digital imaging

合理设计多电子转移机制实现更好的水系锌-有机电池

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Science China materials 2024年第5期67卷 1367-1378页

作者： Kovan Khasraw abdalla 王越洋 Kozhi Khasraw abdalla 熊嘉伟李琦王斌孙晓明赵逸 State Key Laboratory of Chemical Resource Engineering Beijing University of Chemical TechnologyBeijing100029China Department of Biomedical Science Komar University of Science and TechnologySulaimaniyahIraq College of Education University of GeorgiaAthensGA30605USA minmetals Exploration&Development CO. LTDBeijing100010China Advanced Technology Research Institute Beijing Institute of TechnologyJinan250300China

由于环境相容性好、分子结构可定制和有机物资源丰富等优势,水系锌-有机物电池(AZOBs)成为构建新一代大规模储能系统的关键技术.然而,电导率差、有机物溶解和单一活性基团等问题严重限制了有机物正极材料的倍率性能、稳定性和比容量.因... 详细信息

由于环境相容性好、分子结构可定制和有机物资源丰富等优势,水系锌-有机物电池(AZOBs)成为构建新一代大规模储能系统的关键技术.然而,电导率差、有机物溶解和单一活性基团等问题严重限制了有机物正极材料的倍率性能、稳定性和比容量.因此,具备多氧化还原中心和稳定骨架的有机物正极材料对于实现高性能有机物正极材料至关重要.这些多官能团有机物可协同作用并激发基于多电子转移的氧化还原反应,进而促进H^(+)/Zn^(2+)共嵌以显著提升电池性能.本文探索了多官能团有机物电极的分子结构与其氧化还原反应机理之间的构效关系.本文综述了多官能团有机正极材料在提高氧化还原电位、比容量、动力学以及稳定性等方面面临的挑战和解决策略,为进一步开发先进AZOBs的关键正极材料提供了重要基础.

关键词： aqueous zinc organic battery multifunctional organic cathodes energy storage mechanism molecular structure optimization high performance