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Bacterial and fungal endophthalmitis in Upper Egypt:related species and risk factors

Asian Pacific Journal of Tropical Biomedicine 2012年第8期2卷 655-659页

作者： aa gharamah AM Moharram MA Ismail AK AL-Hussaini School of Biological Sciences Universiti Sains Malaysia Department of Botany Faculty of SciencesAssiut University Department of Ophthalmology Faculty of MedicineAssiut University

Objective:To study risk factors,contributing factors of bacterial and fungal endophthalmitis in Upper Egypt,test the isolated species sensitive to some therapeutic agents,and to investigate the air-borne bacteria and fungi in opthalmology operating ***:Thirty one cases of endophthalmitis were clinically diagnosed and microbiologically *** air-borne bacteria and fungi inside four air-conditioned operating rooms in the Ophthalmology Department at Assiut University Hospitals were also *** isolated microbes from endophthalmitis cases were tested for their ability to produce some extracellular enzymes including protease,lipase,urease,phosphatase and *** the ability of 5 fungal isolates from endophthalmitis origin to produce mycotoxins and their sensitivity to some therapeutic agents were ***:Results showed that bacteria and fungi were responsible for infection in 10 and 6 cases of endophthalmitis,respectively and only 2 cases produced a mixture of bacteria and *** was the most prevalent risk factor of endophthalmitis where 58.1%of the 31 cases were due to *** ophthalmology operating rooms,different bacterial and fungal species were isolated.8 bacterial and 5 fungal isolates showed their ability to produce enzymes while only 3 fungal isolates were able to produce *** showed the highest effect against most isolates in ***:The ability of bacterial and fungal isolates to produce extracellular enzymes and mycotoxins may be aid in the invasion and destruction of eye tissues. Microbial contamination of operating rooms with air-borne bacteria and fungi in the present work may be a source of postoperative endophthalmitis.

关键词： Bacterial Fungal Endophthalmitis Upper Egypt Risk factors Trauma Ophthalmic surgery

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