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Enha.ced positive humidity sensitive beha.ior of p-reduced gra.hene oxide decora.ed with n-WS_(2) na.opa.ticles

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Ra.e Meta.s 2021年第7期40卷 1762-1767页

作者： Za.-Hua.Dua. Qiu-ni Zha. Cheng-Zhen Li Si Wa.g ya-Dong Jia.g ya-Jie Zha.g Bo-Ha. Liu Hui-Ling Ta. Sta.e Key La.ora.ory of Electronic Thin Films a.d Integra.ed Devices School of Optoelectronic Science and EngineeringUniversity of Electronic Science and Technology of ChinaChengdu 610054China

Most resista.ce-type humidity sensors exhibit nega.ive humidity sensitivity,i.e.,their resista.ce decrea.es with a.corresponding increa.e in *** is prima.ily a.tributed to the domina.t role of ionic conduction in a.sorbed *** this work,a.humidity sensor ba.ed on a.p-type reduced gra.hene oxide(p-rGO)with positive humidity sensitivity is ***,its positive humidity sensing response is further enha.ced by n-type WS_(2) na.opa.ticles *** results show tha. both rGO a.d r GO/WS_(2) humidity sensors ha.e good linea. response in the rela.ive humidity(RH)ra.ge of0%-91.5%.The sensitivity of the rGO/WS_(2) humidity sensor is 1.87 times tha. of rGO humidity sensor,which is ma.nly a.tributed to p-n heterojunction between rGO a.d WS_(2).Besides,the r GO/WS_(2) humidity sensor ha. sma.l humidity hysteresis(-3%RH)a.d good *** work demonstra.es a.humidity sensor ba.ed on rGO/WS_(2) composite film a.d provides a.fa.ile route for fa.rica.ing humidity sensor with positive humidity sensing properties.

关键词： Reduced gra.hene oxide WS2 na.opa.ticles Heterojunction Humidity sensor Humidity sensing mecha.ism

a.socia.ion between islet a.toa.tibodies a.d the preva.ence of a.toimmune uveitis

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Interna.iona. Journa. of Ophtha.mology(English edition) 2020年第11期13卷 1733-1738页

作者： Yun Zha.g ni yan ya Li Wei-Mei Ma.Hong-Li Liu Jing-ni Yu Le Ma Xi'a. People's Hospita.(Xi'a. Fourth Hospita.) Xi'an 710004Shaanxi ProvinceChina School of Public Hea.th Xi'an Jiaotong UniversityXi'an 710061Shaanxi ProvinceChina

a.M:To eva.ua.e the predictive va.ue of islet a.toa.tibodies for the dia.nosis of a.toimmune uveitis(a.),a. well a. to cha.a.terize the a.socia.ion bet ween islet a.toa.tibodies a.d ***:Tota.ly 97 pa.ients with a. a.d 100 hea.thy persons without a.y a.toimmune disea.es a. the control group were *** serum islet a.toa.tibodies were mea.ured using commercia. enzyme-linked immunosorbent a.sa. kits(ELISa..a.supplementa.y questionna.re wa. used to complement the subject's demogra.hics a.d clinica. *** level of glucose concentra.ions a.d white blood cells were *** logistic regression wa. performed to estima.e odds ra.ios(ORs),a.d 95%confidence interva.s(CIs)of a. a.cording to islet a.toa.tibodies a.d to eva.ua.e the predictive va.ue of islet a.toa.tibodies for a. *** subgroups a.d other va.ia.les were included into ***:In a. pa.ients,the preva.ence of detecting a. lea.t one of the a.toa.tibodies wa. 31.9%(31/97).The most frequent a.toa.tibody wa. ZnT8a.30.9%),followed by Ga.a.11.3%),Ia.2a.4.1%),ICa.2.1%)a.d Ia.(2.1%).Islet a.toa.tibodies were found to be correla.ed positively with a. dia.nosis[OR(95%CI):13.86(3.28,58.50),Pa.wa. rema.ka.ly correla.ed with a. dia.nosis[OR(95%CI):6.13(1.96,19.17),Pa.t,neither Ga.a.nor other islet a.tibodies(Ia.2a.ICa.a.d Ia.)showed a.y a.socia.ion with a. risk under a. a.ditive ***:The preva.ence of islet a.tibodies,especia.ly ZnT8a.in pa.ients with a. is *** a.tibodies a. well a. novel bioma.kers should be included in routine eva.ua.ion a. a. a.d is a.va.ua.le biologica. ma.ker to cla.sify newly-dia.nosed uveitis.

关键词： a.toimmune uveitis islet a.toa.tibody ZnT8A epidemiology

Pha.e-field simula.ion of seconda.y dendrite growth in directiona. solidifica.ion of bina.y a.loys

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China.Foundry 2019年第2期16卷 97-104页

作者： Li Feng ni-ni Lu ya-long Ga. Cha.g-sheng Zhu Jun-he Zhong Rong-zhen Xia. College of Ma.eria.s a.d Engineering Lanzhou University of Technology Sta.e Key La.ora.ory of a.va.ced Processing a.d Recycling of Non-ferrous Meta.s Lanzhou University of Technology

Pha.e field method wa. used to simula.e the effect of gra.ns orienta.ion a.gle θ_(11) a.d a.imuth θ_a.of non-preferentia.ly growing dendrites on the seconda.y dendrites of preferentia.ly growing dendrites. In the simula.ion process, two single-fa.tor influence experiments were designed for columna. crysta. structures. The simula.ion results showed tha., when θ_(11) a.d θ_a.a. θ_(11) wa. enla.ged, the growth direction of the seconda.y dendrites on the preferentia.ly growing dendrites a. the converging gra.n bounda.y(GB) presented a. increa.ing inclina.ion to tha. of preferentia.ly growing dendrites; with increa.ing θ_a. the growth direction of the seconda.y dendrites on the preferentia.ly growing dendrites a. the converging GB exhibited grea.er deflection,a.d the seconda.y dendrites grew with bra.ches; the seconda.y dendrites on the preferentia.ly growing dendrites a. diverging GBs grew a.ong a.direction vertica. to the growth direction of the preferentia.ly growing *** θ_a.= 45o a.d θ_(11) = 45o, the seconda.y dendrites grew in a.direction vertica. to the growth direction of preferentia.ly growing dendrites. The morphologies of the dendrites obta.ned through simula.ion ca. a.so be found in meta.logra.hs of pra.tica. solidifica.ion experiments. This implies tha. the effect of a.gra.n's orienta.ion a.gle a.d a.imuth of non-preferentia.ly growing dendrites on the seconda.y dendrites of preferentia.ly growing dendrites does exist a.d frequently a.pea.s in the pra.tica. solidifica.ion process.

关键词： pha.e-field method bina.y a.loy directiona. solidifica.ion seconda.y dendrites

The expression of Lin28B wa. co-regula.ed by H3K4me2 a.d Wnt5a.β-ca.enin/TCF7L2

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Journa. of Integra.ive a.riculture 2020年第12期19卷 3054-3064页

作者： ZHa.G ya-ni HU Ca. Wa.G Ying-jie ZUO Qi-sheng LI Bi-chun Key La.ora.ory of a.ima. Breeding Reproduction a.d Molecula. Design for Jia.gsu Province College of Animal Science and TechnologyYangzhou UniversityYangzhou 225009P.R.China Joint Interna.iona. Resea.ch La.ora.ory of a.riculture a.d a.ri-Product Sa.ety of Ministry of Educa.ion Yangzhou UniversityYangzhou 225009P.R.China

Lin28a.a.d Lin28B a.e homologous RNa.binding proteins tha. pa.ticipa.e in the development of primordia. germ cells. The mecha.isms underlying expression a.d regula.ion of Lin28a.ha.e been well documented, but such informa.ion for Lin28B is limited. In this study, a.fra.ment of the Lin28B promoter wa. cloned, the pEGFP-pLin28B vector wa. constructed. DF-1 chicken fibrobla.ts were tra.sfected a.d the expression of green fluorescent protein (GFP) wa. mea.ured. Furtherly, Lin28B promoter of different lengths fra.ments wa. cloned using the chromosome-wa.king method a.d the fra.ments were liga.ed into the PGL3-Ba.ic vector, a.d tra.sfected into DF-1 cells. Results of dua.-lucifera.e reporter a.sa. showed tha. the core of the Lin28B promoter wa. included in the sequence from –1 431 to –1 034 bp. The binding sites of the tra.scription fa.tor TCF7L2 wa. showed within this sequence by bioinforma.ics a.a.ysis. The promoter a.tivity of Lin28B wa. downregula.ed (Pa. muta.ed. Further experiments suggested tha. Lin28B promoter a.tivity responded to the a.tiva.ion or inhibition of Wnt signa.ing. Results of chroma.in immunoprecipita.ion a.d qua.tita.ive PCR showed tha. β-ca.enin-TCF7L2 ma. be enriched in the Lin28B promoter core a.ea. In vivo a.d in vitro a.tiva.ion or inhibition of Wnt signa.ing significa.tly up- or down-regula.ed (Pa.fected the regula.ion of Wnt signa.ing to Lin28B. In conclusion, our results showed tha. H3K4me2 a.d Wnt5a.β-ca.enin/TCF7L2 were the positive regula.ors of Lin28B expression. Findings of this study ma. la. a.theoretica. founda.ion for illumina.ing the mecha.ism underlying Lin28B expression.

关键词： primordia. germ cells Lin28B promoter H3K4me2 Wnt5a.β-ca.enin/TCF7L2

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已有结构新增钢梁加固施工工艺

建筑与装饰 2024年第6期 178-180页

作者：段嘉辉胡亚召倪方森中建三局中原分公司河南郑州 450000

新工艺采用新型装配式、可调胎架进行新增钢梁安装.胎架由叉车前端固定,新增钢梁放置在其上,通过限位柱防止位移.叉车顶升加固钢梁至标高,另一叉车运送提前焊接的支撑架至钢梁下方,安装可拆卸支架、顶托与楼板紧密连接.支撑架与千斤顶... 详细信息

新工艺采用新型装配式、可调胎架进行新增钢梁安装.胎架由叉车前端固定,新增钢梁放置在其上,通过限位柱防止位移.叉车顶升加固钢梁至标高,另一叉车运送提前焊接的支撑架至钢梁下方,安装可拆卸支架、顶托与楼板紧密连接.支撑架与千斤顶协同使用,实现不同截面钢梁的快速安装,支撑架快速周转.本文详细介绍了该工艺,突显大型叉车、新型装配式可调胎架、可调支撑架的协同作业,为高效加固老旧建筑提供了有效手段.

关键词：航站楼支撑架改扩建工程钢梁加固

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基于多属性决策的垃圾焚烧飞灰处理技术比选

广州化工 2024年第16期52卷 96-99页

作者：陈泥程唐成黎张亚兰重庆化工职业学院重庆401228 中国石油工程建设有限公司西南分公司四川成都610043

垃圾焚烧飞灰中的重金属和二噁英等物质对环境具有显著的危害,运用固化技术、药剂稳定化技术、高温热处理技术、水热技术等处理飞灰正是研究的热点技术。鉴于不同的飞灰处理技术各有优劣,本文建立了多准则决策模型来对其进行比选。构建... 详细信息

垃圾焚烧飞灰中的重金属和二噁英等物质对环境具有显著的危害,运用固化技术、药剂稳定化技术、高温热处理技术、水热技术等处理飞灰正是研究的热点技术。鉴于不同的飞灰处理技术各有优劣,本文建立了多准则决策模型来对其进行比选。构建的多属性决策中包含指标体系建立、指标数据采集、指标权重确定、备选方案排序四个步骤,可对不同飞灰处理技术进行多维的评价。

关键词：垃圾焚烧多属性决策方法飞灰处理技术 FUCOM方法

Monoclona. a.tibody-conjuga.ed Polyphosphoester-hyd-DOX Prodrug Na.opa.ticles for Ta.geted Chemothera.y of Liver Ca.cer Cells

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Chinese Journa. of Polymer Science 2021年第11期39卷 1392-1402页

作者： ya-Kui Hua.g Hong-Rui Tia. Ming-Zu Zha.g Jin-Lin He Jia. Liu Pei-Hong ni College of Chemistry Chemical Engineering and Materials ScienceState and Local Joint Engineering Laboratory for Novel Functional Polymeric MaterialsJiangsu Key Laboratory of Advanced Functional Polymer Design and ApplicationSuzhou Key Laboratory of Macromolecular Design and Precision SynthesisSoochow UniversitySuzhou 215123China Institute of Functiona. Na.o a.d Soft Ma.eria.s(FUNSOM) Soochow UniversitySuzhou 215123China

In order to overcome the limita.ion of tra.itiona. a.tive na.o-thera.eutic drugs on tumor ta.geting efficiency which ca.not rea.h the receptor/ta.get in sufficient a.ount in the body,in this work,we developed a.monoclona. a.tibody(ma.)a.d a.polymer-hyd-doxorubicin prodrug conjuga.e,which ena.les the self-a.sembled na.opa.ticles to ha.e precise ta.geting,tumor tissue a.grega.ion a.d pH-sensitive drug *** first prepa.ed a. a.phiphilic polymer prodrug,a.brevia.ed a. H2N-PEEP-b-PBYP-hyd-DOX,via.a.combina.ion of ring-opening polymeriza.ion(ROP)a.d"click"chemistry,in which PEEP a.d PBYP represent two kinds of phosphoester segmemts,-hyd-is hydra.one *** self-a.sembly into prodrug na.opa.ticles(PDNPs)with a.dia.eter of a.out 93 nm,CD147 ma. wa. conjuga.ed onto the PDNPs by EDC/NHS chemistry to form *** the PDNPs a.d ma.-PDNPs,we a.so investiga.ed their sta.ility,in vitro drug relea.e beha.ior a.d cellula. *** results showed tha. the pH-responsive PDNPs ca. rema.n rela.ively sta.le under the condition of PB 7.4 buffer ***,under a.idic conditions or in the presence of phosphodiestera.e I(PDE I),both the a.ount a.d ra.e of DOX relea.e increa.ed a. the sa.e incuba.ion *** a.sa. showed tha. ma.-PDNPs exhibited higher cytotoxicity(IC50:1.12 mg·L^(-1))a.a.nst HepG2 cells tha. PDNPs(IC50:2.62 mg·L^(-1))without monoclona. *** na.opa.ticles with a.tibodies ma.-PDNPs ha.e rela.ively better sta.ility a.d ca. directly a.hieve the ta.geting drug delivery through CD147 ma..

关键词： Monoclona. a.tibody Polymeric prodrug Polyphosphoester Drug delivery Ta.geted thera.y

基于实验参数的Dy^(3+),Na.(+):PbGa.(2)S_(4)中红外激光理论研究

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物理学报 2024年第16期73卷 72-81页

作者：余学舟黄昌保吴海信胡倩倩刘国晋李亚朱志成祁华贝倪友保王振友中国科学院合肥物质科学研究院安徽光学精密机械研究所安徽省光子器件与材料重点实验室合肥230031 中国科学技术大学合肥230026

基于加工出的Dy^(3+),Na.(+):PbGa.(2)S_(4)晶体元件的吸收光谱测试以及Judd-Ofelt理论计算数据,通过互易法计算出各发光能级间的荧光吸收与发射截面.通过测试与计算得到的数据,数值模拟了采用1.3μm和1.7μm泵浦源直接抽运Dy^(3+),Na.(... 详细信息

基于加工出的Dy^(3+),Na.(+):PbGa.(2)S_(4)晶体元件的吸收光谱测试以及Judd-Ofelt理论计算数据,通过互易法计算出各发光能级间的荧光吸收与发射截面.通过测试与计算得到的数据,数值模拟了采用1.3μm和1.7μm泵浦源直接抽运Dy^(3+),Na.(+):PbGa.(2)S_(4)晶体产生4.3μm中红外激光的实验方案.计算分析了激光功率、增益和吸收系数在晶体内的空间分布,分析比较了泵浦光功率、元件长度和输出镜反射率对输出功率的影响.模型中在光路中引入2.9μm级联激光振荡,以此抽运因为4.3μm发光堆积在能级^(6)H_(13/2)上的粒子数,发现其可以有效降低能级^(6)H_(11/2)到^(6)H_(13/2)跃迁的自终止效应,提高激光输出功率.计算结果表明:采用1.3μm和1.7μm泵浦源,当功率都为4 W时,最大的输出功率分别为103 mW和315 mW,斜率效率可达到2.8%和8.0%.数值模拟的结果对下一步晶体元件的改良加工以及光路搭建参数的选取提供了一定的指导意义.

关键词：中红外激光数值模拟 PbGa.(2)S_(4) 晶体

Ta.RR1, a.cytokinin response regula.or gene in Triticum a.stivum, is essentia. in pla.t N sta.va.ion tolera.ce via.regula.ing the N a.quisition a.d N a.simila.ion

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Journa. of Integra.ive a.riculture 2019年第12期18卷 2691-2702页

作者： yaNG Meng-ya CHEN Jia.qi TIa. He-yang ni Chen-yang XIa. Ka. College of a.ronomy Hebei Agricultural University/Key Laboratory of Crop Growth Regulation of Hebei Province

Pla.t N sta.va.ion response is closely a.socia.ed with the N signa.ing components tha. involve tra.sduction of the low-N cues. In this study, we functiona.ly cha.a.terized Ta.a.R1, a.cytokinin(CK) response regula.or gene in Triticum a.stivum, in media.ing the N sta.va.ion a.a.ta.ion in pla.ts. Ta.a.R1 ha.bors two conserved doma.ns specified by pla.t a.R fa.ily members;subcellula. loca.iza.ion a.a.ysis indica.ed its ta.get onto nucleus a.ter endopla.mic reticulum a.sortment. Ta.a.R1 displa.ed modified expression upon the N sta.va.ion stressor, showing upregula.ed expression in roots a.d lea.es over a.27-h N sta.va.ion trea.ment a.d whose induced tra.scripts were gra.ua.ly recovered a.ong with progression of the N recovery trea.ment. The toba.co lines overexpressing Ta.a.R1 displa.ed improved low-N stress tolera.ce, displa.ing enla.ged phenotype, increa.ed bioma.s a.d N a.cumula.ion, a.d enha.ced gluta.ine syntheta.e(GS) a.tivities compa.ed with wild type(WT) following the N sta.va.ion trea.ment. Expression a.a.ysis on genes encoding the nitra.e tra.sporter(NRT) a.d GS proteins in nicotia.a.ta.a.um revea.ed tha. Nt NRT2.2 a.d Nt GS3 a.e upregula.ed in expression in the N-deprived tra.sgenic lines, whose expression pa.terns were contra.ted to other a.ove fa.ily genes tha. were una.tered on tra.scripts between the tra.sgenic lines a.d WT. Tra.sgene a.a.ysis va.ida.ed the function of Nt NRT2.2 a.d Nt GS3 in regula.ing N a.cumula.ion, GS a.tivity, growth tra.ts, a.d N use efficiency in pla.ts. These results suggested the interna. connection between the Ta.a.R1-media.ed N sta.va.ion tolera.ce a.d the modified tra.scription of distinct N a.quisitiona.d a.simila.ion-a.socia.ed genes. Our investiga.ion together indica.es tha. Ta.a.R1 is essentia. in pla.t N sta.va.ion a.a.ta.ion due to the gene function in tra.scriptiona.ly regula.ing distinct NRT a.d GS genes tha. a.fect pla.t N upta.e a.d a.simila.ion under the N sta.va.ion condition.

关键词： whea.(Triticum a.stivum L.) cytokinin response regula.or gene expression N sta.va.ion functiona. cha.a.teriza.ion