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Herbal compounds as promising therapeutic agents in precision medicine strategies for cancer:A systematic review

Journal of Integrative medicine 2024年第2期22卷 137-162页

作者： Bizhar a.med tayeb Ikhwan Yuda Kusuma Alaa A.M.Osman Renáta Minorics Institute of Pharmacodynamics and Biopharmacy Faculty of PharmacyUniversity of Szeged6720 SzegedHungary Institution of Clinical Pharmacy Faculty of PharmacyUniversity of Szeged6725 SzegedHungary Department of Clinical Pharmacy and Pharmacy Practice Faculty of PharmacyUniversity of Gezira20 Wad MadaniSudan Pharmacy Study Program Facuity of HealthUniversitas Harapan BangsaPurwokerto 53182Indonesia

Background:The field of personalized medicine has gained increasing attention in cancer care,with the aim of tailoring treatment strategies to individual patients for improved *** medicine,with its long-standing historical use and extensive bioactive compounds,offers a rich source of potential treatments for various diseases,including ***:To provide an overview of the current knowledge and evidence associated with incorporating herbal compounds into precision medicine strategies for cancer ***,to explore the general characteristics of the studies included in the analysis,focusing on their key features and *** strategy:A comprehensive literature search was conducted from multiple online databases,including Pub med,Scopus,Web of Science,and *** search strategy was designed to identify studies related to personalized cancer medicine and herbal *** criteria:Publications pertaining to cancer research conducted through in vitro,in vivo,and clinical studies,employing natural products were included in this *** extraction and analysis:Two review authors independently applied inclusion and inclusion criteria,data extraction,and assessments of methodological *** quality assessment and biases of the studies were evaluated based on modified Jadad scales.A detailed quantitative summary of the included studies is presented,providing a comprehensive description of their key features and ***:A total of 121 studies were included in this review for *** of them were considered as comprehensive experimental investigations both in vitro and in *** majority(n=85)of the studies included in this review were conducted in vitro,with 44 of them specifically investigating the effects of herbal medicine on animal ***,7 articles with a combined sample size of 31,271 patients,examined the impact of herbal medicine in clinical ***:Personal

关键词： Cancer Herbal medicine Personalized medication Active phytochemicals Natural compound

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Voltage property analysis of piezoelectric floating mass actuator used in middle ear implant

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Journal of Southeast University(English Edition) 2009年第4期25卷 496-500页

作者：刘后广塔娜饶柱石上海交通大学机械系统与振动国家重点实验室上海200240

Aiming at a kind of middle ear implant（MEI）, the driving voltage of a piezoelectric floating mass actuator is analyzed using a 0. 7Pb （Mg1/3Nb2/3） O3-0. 3PbTiO3 （ PMN- 30% PT）stack as a new type of vibrator. For the purpose of facilitating the analysis, a simplified coupling model of the ossicular chain and the piezoelectric actuator is constructed. First, a finite element model of a human middle ear is constructed by reverse engineering technology, and the validity of this model is confirmed by comparing the simulated motion of the stapes footplate obtained by this model with experimental measurements. Then the displacement impedance of the incus long process is analyzed, and a single mass-spring-damper equivalent model of the ossicular chain a.ta.hed with the clamp is derived. Finally, a simplified coupling model of the ossicular chain and the piezoelectric actuator is established and used to analyze the driving voltage property of the actuator. The results show that the required driving voltage decreases with the increase in the frequency, and the maximum required driving voltage is 20. 9 V in the voice frequencies. However, in the mid-high frequencies where most sensorineural hearing loss occurs, the maximum required driving voltage is 3.8 V, which meets the low-voltage and low-power requirements of the MEI.

关键词： middle ear implant piezoelectric actuator floating mass driving voltage

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高分辨率超声Lamb波频散曲线测量与板厚估计

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数据采集与处理 2017年第2期32卷 286-292页

作者：许凯亮张正罡刘丹他得安胡波巴黎第六大学法国国家科学研究院国家卫生与医学研究院生物医学成像实验室(LIB) 法国巴黎75006 复旦大学电子工程系上海200433 上海市医学图像处理与计算机辅助手术重点实验室上海200032

超声Lamb波在工业无损检测与评价中具有广阔的应用前景。但受制于超声导波多模式频散与混叠的影响,如何实现高分辨率超声导波的模式分离与频散曲线提取,进而定量分析材料的健康状况一直是研究的热点与难点。本文旨在将现代信号处理中广... 详细信息

超声Lamb波在工业无损检测与评价中具有广阔的应用前景。但受制于超声导波多模式频散与混叠的影响,如何实现高分辨率超声导波的模式分离与频散曲线提取,进而定量分析材料的健康状况一直是研究的热点与难点。本文旨在将现代信号处理中广泛采用的谱估计技术应用于超声Lamb波阵列信号分析,并通过提取频散曲线定量测量板厚度。以经典参数谱估计法中的Yule-Walker法与Burg法为例,实验测量和分析了3mm,4mm和5mm厚铝板中的宽带多模式Lamb波信号,准确地提取了铝板中的宽带Lamb波频散曲线,并比较了两种经典谱估计方法与二维傅氏变换法的性能,最终实现了铝板厚度估计。

关键词：超声Lamb波经典谱估计法频散曲线厚度估计无损检测

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