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Quality of life following laparoscopic Nissen fundoplication: Assessing short-term and long-term outcomes

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World Journal of Gastroenterology 2013年第24期19卷 3810-3818页

作者： Ilmo Kellokumpu Markku Voutilainen Caj Haglund Martti Frkkil Peter J roberts Hannu Kautiainen Department of Surgery Central Hospital of Central Finland40620 Jyvskyl Finland Department of Gastroenterology Central Hospital of Central Finland40620 Jyvskyl Finland Department of Surgery Helsinki University Central Hospital Division of Gastroenterology Department of Internal Medicine Helsinki University Central Hospital Department of Surgery Turku University Hospital Biostatistician Unit of Primary Health Care Helsinki University Hospital Department of General Practice Primary Health Care Unit Turku University Hospital

AIM: To investigate the quality of life following lapa-roscopic Nissen fundoplication by assessing short-term and long-term outcomes. METHODS: From 1992 to 2005, 249 patients under-went laparoscopic Nissen fundoplication. Short-term outcome data including symptom response, side effects of surgery, endoscopy, and patient's perception of over-all success were collected prospectively. Long-term out-comes were investigated retrospectively in patients witha median follow-up of 10 years by assessment of reflux symptoms, side effects of surgery, durability of antire-flux surgery, need for additional treatment, patient's perception of success, and quality of life. Antireflux sur-gery was considered a failure based on the following criteria: moderate to severe heartburn or regurgitation; moderate to severe dysphagia reported in combination with heartburn or regurgitation; regular proton pump inhibitor medication use; endoscopic evidence of erosive esophagitis Savary-Miller grade 1-4; pathological 24-h pH monitoring; or necessity to undergo an additional surgery. The main outcome measures were short-and long-term cure rates and quality of life, with patient sat-isfaction as a secondary outcome measure. RESULTS: Conversion from laparoscopy to open sur-gery was necessary in 2.4% of patients. Mortality was zero and the 30-d morbidity was 7.6% (95%CI: 4.7%-11.7%). The median postoperative hospital stay was 2 d [interquartile range (IQR) 2-3 d]. Two hundred and forty-seven patients were interviewed for short-term analysis following endoscopy. Gastro-esophageal reflux disease was cured in 98.4% (95%CI: 95.9%-99.6%) of patients three months after surgery. New-onset dysphagia was encountered postoperatively in 13 patients (6.7%); 95% reported that the outcome was better after antireflux surgery than with preopera-tive medical treatment. One hundred and thirty-nine patients with a median follow-up of 10.2 years (IQR 7.2-11.6 years) were available for a long-term evalu-ation. Cumulativ

关键词： Laparoscopy Nissen fundoplication Long-term outcome Antireflux Gastrointestinal symptom rating scores RAND-36

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The Perfect Village?

新高考(英语进阶) 2016年第Z2期 58-59页

作者： Phillipa.roberts

Titus salt and his material factory Named after both the man who built it and the river it sits on,Saltaire was created in 1851,when Victoria was *** our tour of the village near Bradford in Yorkshire,the heart of nor... 详细信息

关键词： work very

Design,Development and Testing of the JTech Bolt for Use in Static,Quasi-Static and Dynamic Domains

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Journal of Civil Engineering and Architecture 2024年第6期18卷 282-295页

作者： Trent roberts Jennmar Australia Pty Ltd. 40-44 Anzac Avenue Smeaton Grange NSW 2567Australia

Designing a rock reinforcement element requires knowledge of:geomechanical behaviour,interaction of the reinforcement element with rock mass and the element’s mechanistic response in static and dynamic *** this knowledge the JTech bolt was developed and subjected to a thorough program to test,gather data and validate the bolt performance in varying *** conducting FE(finite element)modeling,the simulation reviews the JTech bolt design evaluating the effects of threadbar geometric variation,threadbar and nut engagement results under high stress,coating friction response and effects of thread tolerance extremes on the failure *** results determine safety factors,tolerances and quality management *** manufactured,in-situ system testing,laboratory and underground short encapsulation testing,resin mixing testing,double shear testing and dynamic testing at varying velocity and mass,determine the system’s capacity and effectiveness in static,quasi-static and dynamic mining *** this paper,the process and results are described.

关键词： Rock reinforcement geomechanical behavior static quasi-static dynamic domains

Molecular biology of heart disease

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World Journal of Cardiology 2011年第4期3卷 121-126页

作者： Robert roberts Ruddy Canadian Cardiovascular Genetics Centre University of Ottawa Heart Institute

Dr. Robert roberts is currently Professor of Medicine and Director of the Ruddy Canadian Cardiovascular Genetics Centre along with being President and CEO of the University of Ottawa Heart Institute. Prior to this appointment, he was Chief of Cardiology for 23 years at Baylor College of Medicine, Houston, Texas. His original research was in cardiac enzymology which led to the development of the MBCK test which was the standard diagnostic assay for myocardial infarction for more than 3 decades. In the late 1970s, his research interests switched to molecular biology and the genet- ics of cardiomyopathies. He is regarded as one of the founders of molecular cardiology and has identified and sequenced more than 20 genes responsible for cardiovascular disorders. In the past 6 years, he has pursued genome-wide association studies to identify genes predisposing to coronary artery disease (CAD) and myocardial infarction. The first genetic variant for CAD, 9p21, was identified by Dr. Robert’s laboratory and, in collaboration with the international consortium, CARDIoGRAM, has identified 13 novel genes for CAD.

关键词： Molecular biology Genetics Heart disease Genome wide association studies Genetic linkage Cre- atine kinase

Etiology and management of urethral calculi:A systematic review of contemporary series

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Asian Journal of Urology 2024年第1期11卷 10-18页

作者： Andrew Morton Arsalan Tariq Nigel Dunglison Rachel Esler Matthew J.roberts Faculty of Medicine The University of QueenslandBrisbaneQueenslandAustralia Department of Urology Ipswich HospitalQueenslandAustralia Department of Urology Royal Brisbane and Women's HospitalQueenslandAustralia The University of Queensland Centre for Clinical Research HerstonAustralia

Objective:To conduct a systematic literature review on urethral calculi in a contemporary cohort describing etiology,investigation,and management ***:A systematic search of MEDLINE and Cochrane Central Register of Controlled Trials(CENTRAL)databases was ***,including case reports and case series on urethral calculi published between January 2000 and December 2019,were ***-text manuscripts were reviewed for clinical parameters including symptomatology,etiology,medical history,investigations,treatment,and *** were collated and analyzed with univariate ***:Seventy-four publications met inclusion criteria,reporting on 95 *** symptoms(41.1%),pain(40.0%),and acute urinary retention(32.6%)were common presenting *** calculi were most often initially investigated using plain X-ray(63.2%),with almost all radio-opaque(98.3%).Urethral calculi were frequently associated with coexistent bladder or upper urinary tract calculi(16.8%)and underlying urethral pathology(53.7%)including diverticulum(33.7%)or stricture(13.7%).Urethral calculi were most commonly managed with external urethrolithotomy(31.6%),retrograde manipulation(22.1%),and endoscopic in situ lithotripsy(17.9%).Conclusion:This unique systematic review of urethral calculi provided a summary of clinical features and treatment trends with a suggested treatment *** in contemporary urological practice should be according to calculus size,shape,anatomical location,and presence of urethral pathology.

关键词： Urinary calculi Urethra Urethral calculi Management algorithm

Have the Covid-19 Lockdowns Made Lasting Changes to Everyday Life? Evidence from UK Time Use Surveys

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Sociology Study 2023年第4期13卷 175-187页

作者： Ken roberts University of Liverpool LiverpoolUK

This paper asks whether the turbulence of the Covid-19 lockdowns has left enduring changes to everyday life in the UK which are unlikely to have happened,up to now,in the absence of the *** analysis disaggregates the UK population by gender,and into age groups and income bands,specifies whose lives were changed during the lockdowns,and exactly *** is argued that most changes from pre-to post-lockdowns have been spurts in longer-running trends driven by the UK demographic,housing,economic and political *** exceptions,the sole genuine lockdown legacies that the analysis leaves,are the normalisation of working from home and an increase in total time spent doing paid work.

关键词： age differences Covid-19 pandemic gender differences income bands leisure lockdowns

Distal radius volar rim plate: Technical and radiographic considerations

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World Journal of Orthopedics 2017年第7期8卷 567-573页

作者： Michelle Spiteri Darren roberts Wayne Ng Jamie Matthews Dominic Power Hand Unit Queen Elizabeth Hospital Birmingham University Hospitals Medical School University of Birmingham

AIM To determine technical considerations and radiographic outcomes of the Synthes volar rim distal radius plate to treat complex intra-articular fractures. METHODS This review highlights technical considerations learnt using this implant since it was introduced in a major trauma unit in November 2011, including anatomical reduction and whether this was maintained radiographically. RESULTS Twenty-six of the 382 internally fixed distal radial fractures at our unit(6.8%) were deemed to require this plate in order to achieve optimal fracture fixation between November 2011 and May 2014. A further dorsal and/or radial plate was necessary in 35% and variable angle screws were used in 54% of cases. Postoperatively, mean radial height, inclination, volar tilt and ulnar variance restored were 11.7 mm, 21o, 4.3o and-1.2 mm respectively. There were no cases of non-union or flexor/extensor tendon rupture; one case of loss of fracture reduction. Overall incidence of plate removal was 15% with one plate removed for flexor and one for extensor tendon irritation CONCLUSION The use of a rim plate enables control of challenging fardistal fracture patterns. However, additional plates were required to improve and maintain reduction. Variable angle screws were necessary in half the cases to avoid intra-articular screw penetration. If used judiciously, this implant can achieve stable fixation despite the complexity of the fracture pattern.

关键词： Distal radius fractures Volar rim plate Volar plating distal radius

Dynamics of Nitrogen Speciation in Horticultural Soils in Suburbs of Shanghai,China

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Pedosphere 2010年第2期20卷 261-272页

作者： GE Ti-Da HUANG Dan-Feng P. roberts D. L. JONES SONG Shi-Wei School of Agriculture and Biology Shanghai Jiao Tong University Shanghai 201101 (China) School of the Environment and Natural Resources University of Wales Bangor Gwynedd LL57 2UW (UK) Key Laboratory of Agro-ecological Processes in Subtropical Region Institute of Subtropical Agriculture Chinese Academyof Sciences Hunan 410125 (China)

Dissolved organic nitrogen （DON） represents a significant pool of soluble nitrogen （N） in soil ecosystems. Soil samples under three different horticultural management practices were collected from the Xiaxiyang Organic Vegetable and Fruit Farm, Shanghai, China, to investigate the dynamics of N speciation during 2 months of aerobic incubation, to compare the effects of different soils on the mineralization of ^14C-labeled amino acids and peptides, and to determine which of the pathways in the decomposition and subsequent ammonification and nitrification of organic N represented a significant blockage in soil N supply. The dynamics of N speciation was found to be significantly affected by mineralization and immobilization. DON, total free amino acids, and NH^＋-N were maintained at very low levels and did not accumulate, whereas NO3^--N gradually accumulated in these soils. The conversion of insoluble organic N to low-molecular-weight （LMW） DON represented a main constraint to N supply, while conversions of LMW DON to NH4^＋-N and NH4^＋-N to NO3^--N did not. Free amino acids and peptides were rapidly mineralized in the soils by the microbial community and consequently did not accumulate in soil. Turnover rates of the additional amino acids and peptides were soil-dependent and generally followed the order of organic soil 〉 transitional soil 〉 conventional soil. The turnover of high-molecular-weight DON was very slow and represented the major DON loss. Further studies are needed to investigate the pathways and bottlenecks of organic N degradation.

关键词： amino acids dissolved organic N mineralization N transformation peptides

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零排放燃气轮机的空气动力学特性

工程热物理学报 2007年第4期28卷 561-564页

作者：单晓明 S A Sjolander S K roberts 南京航空航天大学能源与动力学院加拿大卡尔顿大学

本文对采用二氧化碳作为基本工作流体的半闭环燃气轮机循环的空气动力学特性进行了详尽的分析。结果表明,不同工作流体的比热比值对压气机的压比、等熵效率及临界堵塞质量流量影响很大,并详细阐述了一种比热比对透平机械性能影响的修正... 详细信息

本文对采用二氧化碳作为基本工作流体的半闭环燃气轮机循环的空气动力学特性进行了详尽的分析。结果表明,不同工作流体的比热比值对压气机的压比、等熵效率及临界堵塞质量流量影响很大,并详细阐述了一种比热比对透平机械性能影响的修正方法,进而提出了一种零排放发动机的设计新思路,揭示了最初为空气工质而设计的压气机可以直接用于CO_2零排放发动机中。

关键词： CO2零排放燃气轮机半闭环空气动力学