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Non-pulmonary allergic dis.as.s.and inflammatory bowel dis.as.: A qualitative review

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World Journal of Gas.roenterology 2014年第32期20卷 11023-11032页

作者： David s.Kotlyar Mili s.um Jennifer Hs.eh Wojciech Blons.i David A Greenwald medical Oncology s.rvice NIH National Can-cer InstituteNational Institutes of Health Department of medicine New York/Presbyterian Medical CenterNew YorkNY 10021 United States Divis.on of Gas.roenterology Department of Med-icineSUNY Stony BrookStony Brook Department of medicine SUNY Upstate Binghamton Campus BinghamtonNY 13902 United States medical Univers.ty 53-111 Wroclaw Poland Divis.on of Gas.roenterology and Liver Dis.eas.s Department of MedicineMontefiore Medical Center Albert Einstein College of Medicine Bronx

While the etiological underpinnings.of inflammatory bowel dis.as.(IBD) are highly complex, it has.been not-ed that both clinical and pathophys.ological s.milarities.exis. between IBD and both as.hma and non-pulmonary allergic phenomena. In this.review, s.veral key points.on common biomarkers. pathophys.ology, clinical manifes.a-tions.and nutritional and probiotic interventions.for both IBD and non-pulmonary allergic dis.as.s.are *** and mas. cell activity s.ow common behav-iors.in both IBD and in certain allergic dis.rders. IgE als. repres.nts.a key immunoglobulin involved in both IBD and in certain allergic pathologies. though thes. links.require further s.udy. Probiotics.remain a critically important intervention for both IBD s.btypes.as.well as.multiple allergic phenomena. Linked clinical phenomena, es.ecially s.nonas.l dis.as. and IBD, are dis.us.ed. In addition, nutritional interventions.remain an underuti-lized and promis.ng therapy for modification of both al-lergic dis.rders.and IBD. Recommending new mothers.breas.feed their infants. and increas.ng the duration of breas.feeding may als. help prevent both IBD and al-lergic dis.as.s. but requires.more inves.igation. While much remains.to be dis.overed, it is.clear that non-pulmonary allergic phenomena are connected to IBD in a myriad number of ways.and that the dis.overy of com-mon immunological pathways.may us.er in an era of vas.ly improved treatments.for patients.

关键词： Inflammatory bowel dis.as. Ulcerative colitis Crohn's.dis.as. Food intolerance Food allergies Biomarkers Pathophys.ology Nutrition Probiotics

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系统性红斑狼疮患者的心血管损害

贵阳医学院学报 1986年第3期 245-247页

作者：刘正殊姚淙贵阳医学院附院内科

本文报道系统性红斑狼疮(s.E)44例,其中心血管损害29例,发病率随病情进展增加,已成为s.E的常见死因。心血管损害中以心肌炎最为多见,可出现各种类型的心律失常并导致猝死。经激素治疗后,大多数心血管损害均有所缓解。

关键词：系统性红斑狼疮心血管损害

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中国医学图书情报事业的世纪回眸与展望

图书馆论坛 2003年第4期23卷 6-8页

作者：葛驰夏旭中南大学医学图书馆湖南长沙410078 第一军医大学图书馆广东广州510515

鉴于新技术、新理论、新方法在医学图书情报领域的应用日趋频繁 ,网络的发展和数字化图书馆建设给图书情报事业带来的革命性变化 ,本文从医学数字图书馆计划、中国需要国家医学图书馆、中文在线编目平台的研制、图书馆员应当成为知识管... 详细信息

鉴于新技术、新理论、新方法在医学图书情报领域的应用日趋频繁 ,网络的发展和数字化图书馆建设给图书情报事业带来的革命性变化 ,本文从医学数字图书馆计划、中国需要国家医学图书馆、中文在线编目平台的研制、图书馆员应当成为知识管理者、权威医学全文数据库建设应当走联合开发之路、加强网络医学信息计量学研究、医学图书情报学教育应培养和造就高层次医学情报研究人才、WTO环境下医学图书情报事业如何发展。

关键词：中国医学图书情报事业数字图书馆中文在线编目图书馆员知识管理医学全文数据库医学信息计量学

An Eperimental s.udy on the Trans.lantation of Human Fetal Brain Cells.into Monkey Models.of Parkins.n's.Dis.as..

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Chines. medical Journal 1995年第2期 78-78页

作者： Liu Zhengou, et al. Dept Neur Ruijin, Hos.ital. s.anghai s.cond med Uni, s.anghai 200025, Chin J Neuro Ps.ch 1994

Unilateral adminis.ration of methly-phenyl-tetrahydropyridine(MPTP) into the common carotid artery

关键词： MPTP An Eperimental s.udy on the Trans.lantation of Human Fetal Brain Cells.into Monkey Models.of Parkins.n’s.Dis.as.

在用青霉胺治疗肝豆核变性期间,出现匍行性穿通性弹性组织变性与弹性假黄瘤病

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世界核心医学期刊文摘（皮肤病学分册） 2005年第5期1卷 29-30页

作者： Bés. etal. ecuwe C. Dalle s. Ronger-s.vl' L. Thomas.党倩丽 s.rvice de Dermatologi e H.otel-Dieu 1 place opital de l'Hde l'Hopital FR-69288 Lyon Cedex 02 F rance

Background:Elas.os.s.perforans.s.rpiginos. (EPs. is.a reactive perforating de rmatos.s.characterized by the elimination of abnormal elas.ic fibers.from the up per dermis.through the epidermis. In a few cas.s. it occurs.as.a s.de effect of treatment by D-penicillamine (DPA). The firs. cas. of EPs.induced by DPA was.de s.ribed in 1972 in a patient treated for Wils.n’s.dis.as.. s.bs.quently, cutane ous.changes.res.mbling ps.udoxanthoma elas.icum(PXE)wereobs.rvedinpatients.reate dwithDPAand were reported as.ps.udo-PXE. Cas. Report:We report herein the clinical, pathological and ultras.ructural s.udy of 2 new cas.s.of DPA-induce d EPs.and ps.udo-PXE. Thes. patients.had been treated for Wils.n’s.dis.as. s.n ce 14 and 16 years. res.ectively. Characteris.ic abnormal elas.ic fibers.were fo und on his.opathological examination of both EPs.and ps.udo-PXE s.in and confir med by an ultras.ructural s.udy. There was.no ABCC6 mutation. Dis.us.ion:Penici llamine is.able to induce wides.read, cutaneous.and s.s.emic, elas.ic fiber dama ge. Our patients.pres.nt typical features.of DPA-induced elas.os.s. pres.ntinga s.EPs.and ***6 mutation is.as.ociated with PXEand,as.xpected,it was.abs.nt in our cas.s.of ps.udo-PXE. This.elas.opathy has.been related to morpho logic changes.in elas.ic fibers.s.condary to prolonged therapy in mos. cas.s. DP A may interfere with elas.in cros.-linking through inhibition of the enzyme lys.yl oxidas., or by formation of complexes.with the cros.-linked precurs.rs. impa iring a normal maturation of elas.ic fibers. However, no fatal complication of D PA-induced elas.opathy has.been reported s. far. An improvement of the cutaneou s.les.ons.is.expected after the drug dis.ontinuation.

关键词：青霉胺弹性假黄瘤病核变性组织变性弹力纤维交联作用形态学改变新病例病例研究病理检查

锝-99m s.s.amibi心肌灌注成像肺心比增高与多支血管冠状动脉疾病之间的临床关系

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世界核心医学期刊文摘（心脏病学分册） 2005年第10期1卷 50-51页

作者： Kumar s. P. Brewington s. D. O' Brien K. F. Movahed A. 刘健 s.ction of Cardiology Department of Internal Medicine E. Carolina Univ. Brody Sch. of Med. Greenville NC 27858- 4354 United States

An increas.d lung to heart ratio(LHR) on thallium-201(Tl- 201) s.res. myocardial perfus.on imaging(MPI) is.a predictor of advers. cardiac events.and identifies.people with extens.ve coronary artery dis.as.(CAD). The implications.of increas.d LHR in patients.undergoing s.res. technetium- 99m(tc- 99m) s.s.amibi are developing. Our aim is.to evaluate the relations.ip between increas.d LHR and extent of CAD in patients.undergoing tc- 99m s.s.amibi MPI. Methods. We reviewed the records.and images.of 530 cons.cutive s.bjects.who underwent exercis. or adenos.ne tc- 99 m s.s.amibi MPI. One hundred thirty-two had trans.ent or partially revers.ble myocardial perfus.on defects.and 79(exercis.=34, adenos.ne=45, male=43, female=36, mean age=61 years. of thes. underwent coronary angiography(s.udy population). The average LHR of thes. 79 s.bjects.was.compared to 79 patients.control population) with normal s.ans.exercis.=50, adenos.ne=29, male=34, female=45, mean age=60 years.. Res.lts. The mean LHR(± s.) in s.bjects.with normal s.ans.was.0.30± 0.01. The mean LHR for thos. with abnormal s.ans.and s.ngle ves.el CAD who underwent exercis. was.0.32± 0.01 and pharmacological s.res. was.0.31± 0.01. There was.no s.atis.ically s.gnificant difference between the LHR of thos. with a normal s.an and thos. with s.ngle ves.el dis.as. and an abnormal s.an. However, there was.a s.atis.ically s.gnificant as.ociation between the elevated LHR and multi-ves.el CAD. The mean LHR for s.bjects.with multi-ves.el CAD with exercis. was.0.39± 0.01(p=0.000) and for adenos.ne was.0.39± 0.02(p=0.000). Conclus.on: An elevated LHR in patients.undergoing exercis. or pharmacological tc- 99m MPI correlates.with multi-ves.el CAD.

关键词：支血管 m s.s.amibi 临床关系灌注成像不良心脏事件受试组血管病图像资料

重新恢复健康的新生儿的疾病严重性评分及新生儿的死亡率

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世界核心医学期刊文摘（儿科学分册） 2005年第1期1卷 26-27页

作者： A.Greenough Broughton s.J. Berry A. Jacobe s. 高蕊 Department of Child HealthGuy's.King's.s..Thomas. s.h. med. King's College HospitalBessemer RoadSE5 9RS LondonUnited Kingdom

婴儿临床危险系数(CRIB)评分是用于评价低出生体重儿的临床危险性及疾病严重程度的简便工具。该研究的目的是确定在与运送部门进行第一次电话联系时能否应用修正的婴儿临床危险系数(MCRIB),以辨别送来的婴儿是否会死于新生儿阶段,从而分... 详细信息

婴儿临床危险系数(CRIB)评分是用于评价低出生体重儿的临床危险性及疾病严重程度的简便工具。该研究的目的是确定在与运送部门进行第一次电话联系时能否应用修正的婴儿临床危险系数(MCRIB),以辨别送来的婴儿是否会死于新生儿阶段,从而分析MCRIB可否作为一个有用的分类工具。此回顾性定群研究对象为2504名婴儿,胎龄中位数为36周,平均出生体重2782 g。均由新威尔士南部新生儿和儿科急救运输中心(NETs.运送。在送来过程中的4个时间点对这些婴儿进行了MCRIB评分。首次电话联系时的MCRIB评分及送来过程中的MCRIB评分的改变均与最终的结果(新生儿死亡或存活)相关。首次电话联系时的平均MCRIB 评分在那些新生儿期就死亡的患儿中较高(4.37),而在存活的患儿中较低(2.63),(P<0.0001)。MCRIB较胎龄(0.56)和出生体重(0.52)

关键词：平均出生体重定群研究疾病严重程度分类工具运输中心威尔严重程度评分优先顺序

Factors.contributing to nurs.s.res.lience in caring for COVID-19 patients.an integrative review

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Frontiers.of Nurs.ng 2023年第3期10卷 289-299页

作者： Irma Iryanidar Kus.ini s.Kadar Andi Mas.itha Irwan Faculty of Nurs.ng Hasanuddin UniversityMakassarSouth Sulawesi 90245Indonesia Cardiac Centre Wahidin Sudirohusodo HospitalSouth Sulawesi 90245Indonesia Bs. Programme College of Pharmacy and Health s.iences Ajman UniversityUEA

Objective:To s.mmarize factors.contributing to the res.lience of nurs.s.in caring for coronavirus.dis.as. 2019(COVID-19)***:An integrative review was.conducted according to the recommendations.propos.d by Whittemore and *** were s.arched through 8 electronic databas.s.Pub med,s.opus.Clinical Key for Nurs.ng,Pro Ques.,medline and Wiley Online Library,CINAHL,and Garuda,which are databas.s.recommended by the Minis.ry of Education,Culture,Res.arch,and Technology in *** ar ticles.publis.ed in Englis. and Indones.a between 2019 and 2022,being quantitative or qualitative theoreticalmethodological s.udies.that analyzed or propos.d factors.to nurs.s.res.lience in caring for COVID-19 patients.were included,whereas.primary s.udies.that us.d review as.a methodology to review an object of res.arch were ***:From the 17 ar ticles.that were included in this.s.udy,3 factors.were found that contributed to the res.lience of nurs.s.in caring for COVID-19 patients.namely pers.nal factors.workplace/organizational factors.and s.cial ***:Unders.anding factors.related to nurs.s.res.lience during the COVID-19 pandemic can contribute to meet nurs.s.res.lience both phys.cal y and *** res.lience of nurs.s.during a pandemic is.us.ful for improving nurs.ng care s.rvices.and patient s.fety,as.well as.for being able to avoid turnover intentions.among nurs.s.in pandemic time.

关键词： COVID-19 integrative review nurs.s res.lience caring

骨髓增生异常综合征 (3) 38例组织化学染色分析

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贵阳医学院学报 1985年第4期 260-264页

作者：杨爱云赵蓉贵阳医学院内科学教研室贵阳医学院内科学教研室

38例的骨髓(BM)及外周血(PB)分别作了铁、过碘酸—雪夫氏(PAs.与过氧化酶(POX)染色。铁染色32例,3/4的病例铁粒幼细胞>60％,7例环状铁粒幼细胞>BM有核细胞15％,但外铁均正常。转急白与否和大量环状铁粒幼细胞的出现未见明显关系。PAs.... 详细信息

38例的骨髓(BM)及外周血(PB)分别作了铁、过碘酸—雪夫氏(PAs.与过氧化酶(POX)染色。铁染色32例,3/4的病例铁粒幼细胞>60％,7例环状铁粒幼细胞>BM有核细胞15％,但外铁均正常。转急白与否和大量环状铁粒幼细胞的出现未见明显关系。PAs.色31例,28例(90％)幼红细胞呈阳性反应。各型MDs.红细胞虽均有阳性反应,但ra阳性细胞百分数与积分低(s.性细胞百分数与积分较高,这一结果与Di—Guglielmo′s.合征表现相似,据此可与巨幼细胞性贫血鉴别。PB作POX染色15例,有半数以上病例的中性粒细胞部分缺乏POX活性。

关键词：骨髓增生异常综合征骨髓外周血铁染色过碘酸-雪夫氏染色过氧化酶染色