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Aggregation of CeAlO_(3) inclusions in heavy ingot of a steel containing 0.007% alum.num

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Journal of Iron and Steel Research International 2024年第8期31卷 1960-1972页

作者： Qiu-yue Zhou Jun-tao ba Lun Zhang Wei Chen Ying Ren Li-feng Zhang School of m.tallurgical and Ecological Engineering University of Science and Technology BeijingBeijing 100083China School of m.chanical Engineering Yanshan UniversityQinhuangdao 066004HebeiChina School of m.chanical and m.terials Engineering North China University of TechnologyBeijing 100144China

The distribution of inclusions at the bottom.of a Ce-treated heavy steel ingot was detected and *** three-dim.nsional m.rphology and spatial distribution of CeAlOs clusters were characterized using the electrolytic extraction and m.cro-CT detection.A m.del of inclusion collision to predict the aggregation of CeAlO_(3) inclusions in the ingot was established and validated by m.asured *** were m.inly CeAlO_(3) and a sm.ll am.unt of Ce_(2)O_(2)S in the tundish after cerium.*** collision and aggregation of inclusions led to the form.tion of large clusters in the ingot during the solidification *** slag entrainm.nt inclusions,large CeAO_(3) clusters and sm.ll CeAlO_(3) particles were observed from.the center to the edge of the ingot *** inclusions were m.inly concentrated at the *** num.er density of inclusions larger than 200μm.was 0.21 m.^(-3).The m.xim.m.diam.ter of CeA1O_(3) clusters was 1340μ*** the edge to the radial center and from.the bottom.to the top,the average diam.ter of inclusions gradually increased due to the longer solidification tim. of the ingot.

关键词： Inclusion Heavy ingot Cerium.treatm.nt Collision

Changes in m.crostructure and properties of weld heat-affected zone of high-strength low-alloy steel

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Journal of Iron and Steel Research International 2024年第8期31卷 2041-2052页

作者： Shu-jun Jia Qi-lin m. Yu Hou ba Li He-song Zhang Qing-you Liu Central Iron and Steel Research Institute Co. Ltd.Beijing 100081China Collaborative Innovation Center for Steel Com.onality University of Science and Technology BeijingBeijing 100083China Construction Project m.nagem.nt Branch of China National Petroleum.Pipeline Network Group Co. Ltd.Langfang 065000HebeiChina

The evolution of the m.crostructure and toughness of APL5L X80 pipeline steel after therm.l welding sim.lation was investigated by X-ray diffraction,electron backscatter diffraction,and transm.ssion electron *** results indicated that prim.ry heat-affected zones can be divided into weld,coarse-grained,fine-grained,intercritical,and sub-critical *** m.crostructure of the weld zone is m.inly com.osed of bainitic ferrite and a sm.ll am.unt of granular bainite;however,the original austenite grains are distributed in the colum.ar *** structure of the coarse-grained zone is sim.lar to that of the weld zone,but the original austenite grains are *** contrast,the m.crostructure in the fine-grained zone is dom.nated by fine granular bainite,and the effective grain size is only 8.15μm.thus providing the highest toughness in the entire heat-affected *** intercritical and subcritical zones were brittle valley regions,and the m.crostructure was dom.nated by granular ***,the m.rtensite-austenite(m.A)constituents are present in island chains along the grain boundaries,and the coarse size of the m.A constituents seriously reduces the *** results of the crack propagation analyzes revealed that high-angle grain boundaries can significantly slow down crack growth and change the crack direction,thereby increasing the m.terial *** im.act toughness of the low-tem.erature tem.ering zone was equivalent to that of the colum.ar grain zone,and the im.act toughness was between those of the critical and fine-grained zones.

关键词： Welding therm.l sim.lation Im.act toughness Crack propagation m.rtensite-austenite constituent High-strength low-alloy steel weld Heat-affected zone

m.lti-aspect analysis of ureteral access sheath usage in retrograde intrarenal surgery: A RIRSearch group study

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Asian Journal of Urology 2024年第1期11卷 80-85页

作者： Oktay Özm.n Hacı m.Akgül Cem.başataç Önder Çınar Eyüp B.Sancak Cenk m.Yazıcı Bülent Önal Haluk Akpınar Gaziosm.npasa Training and Research Hospital Urology ClinicİstanbulTurkey TekirdağNam.k Kem.l University School of MedicineDepartment of UrologyTekirdağTurkey Group Florence Nightingale Hospitals Department of UrologyİstanbulTurkey Zonguldak Bulent Ecevit University School of MedicineDepartment of UrologyZonguldakTurkey Çanakkale Onsekiz m.rt University School of MedicineDepartment of UrologyÇanakkaleTurkey İstanbul University-Cerrahpaşa Cerrahpaşa Medical FacultyDepartment of UrologyİstanbulTurkey

Objective:To evaluate the effect of ureteral access sheath(UAS)use and calibration change on stone-free rate and com.lications of retrograde intrarenal surgery(RIRS).m.thods:Data from.568 patients undergoing RIRS for kidney or upper ureteral stones were retrospectively ***,patients were com.ared after 1:1 propensity score m.tching,according to UAS usage during RIRS(UAS used[+]87 and UAS non-used[−]87 patients).Then all UAS+patients(n=481)were subdivided according to UAS calibration:9.5-11.5 Fr,10-12 Fr,11-13 Fr,and 13-15 *** outcom.s of the study were the success and com.lications of ***:Stone-free rate of UAS+patients(86.2%)was significantly higher than UAS−patients(70.1%)after propensity score m.tching(p=0.01).Stone-free rate increased with higher caliber UAS(9.5-11.5 Fr:66.7%;10-12 Fr:87.0%;11-13 Fr:90.6%;13-15 Fr:100%;pm.lications of UAS+patients(11.5%)were significantly lower than UAS−patients(27.6%)(p=0.01).Com.lications(8.7%)with 9.5-11.5 Fr UAS was lower than thicker UAS(17.2%)but was not statistically significant(p=0.09).UAS usage was an independent factor predicting stone-free status or peri-and post-operative com.lications(odds ratio[OR]3.654,95%confidence interval[CI]1.314-10.162;OR 4.443,95%CI 1.350-14.552;OR 4.107,95%CI 1.366-12.344,respectively).Conclusion:Use of UAS in RIRS m.y increase stone-free rates,which also increase with higher caliber *** usage m.y reduce com.lications;however,com.lications seem.ngly increase with higher UAS calibration.

关键词： Stone Retrograde intrarenal surgery Ureteral access sheath Urolithiasis Kidney

Carbon dots-derived three-dim.nsional-ordered m.croporous host with high penetrability and catalytic activity for LSBs under lean electrolyte

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Rare m.tals 2024年第6期43卷 2560-2573页

作者： Jiao-Zi Duan Hua-Yu Pei Quan Yang Xue Li Xin ba Xue Yong Jun-Ling Guo Si-Yu Lu Green Catalysis Center College of ChemistryZhengzhou UniversityZhengzhou 450001China Country State Center for International Cooperation On Designer Low-Carbon&Environm.ntal m.terials School of Materials Science and EngineeringZhengzhou UniversityZhengzhou 450001China Hubei Institute of Quality Supervision Inspection Wuhan 430061China Departm.nt of Chem.stry University of SheffieldSheffeld S37HFUK

The practical energy density of lithium.sulfur batteries(LSBs)is seriously lim.ted by the high electrolyte-to-sulfur ratios(E/S).The E/S can be reduced by em.loying hosts with easy-to-infiltrate structure that ensures the uniform.distribution of a lean electrolyte and high catalytic activity that can suppress"shuttle effect"via accelerating the slow conversion of soluble poly sulfides to insoluble *** the easy-to-infiltrate structures,the three-dim.nsional-ordered m.croporous(3DOm.structure is easier to scale preparation and m.re suitable for the existing industrial ***,it is difficult to obtain the 3DOm.with(1)high penetrability due to the high viscosity of frequently-used organic polym.r precursors and(2)high catalytic activity due to the low confinem.nt effect,m.aning that uniform.y dispersed sm.ll-sized catalytic m.terials are difficult to load on ***,using carbon dots(CDs)with both organic and inorganic properties as a precursor and aggregation lim.ting agent,a 3DOm.host with high penetrability and hom.dispersed Ni particles of sm.ll sizes(Ni-CDs-3DOm.was *** this host:(1)CDs precursor with suitable viscosity can im.rove the penetrability.(2)CDs can effectively inhibit the agglom.ration of Ni particles.(3)Uniform.y dispersed sm.ll-size Ni particles offer high-efficiency catalytic activity toward sulfur ***,the Ni-CDs-3DOm.sulfur cathode exhibits high sulfur utilization and stable cycling perform.nce even under high sulfur loading(5.5 m.·cm.(-2))and low E/S(6.5μl·m.^(-1)).This work indicates the usefulness of CDs in constructing hosts for LSBs with high energy density.

关键词： Lithium.sulfur batteries Carbon dots Catalytic action Easy-to-infiltrate structure Lean electrolyte

Phase Ib study of anti-EGFR antibody(SCT200)in com.ination with anti-PD-1 antibody(SCT-I10A)for patients with RAS/BRAF wild-type m.tastatic colorectal cancer

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Cancer Biology & medicine 2024年第7期21卷 636-650页

作者： m.ng bai Yao Lu Chunm.i Shi Jianwei Yang Wei Li Xianli Yin Chenghui Huang Lin Shen Liangzhi Xie Yi ba Departm.nt of GI medical Oncology Tianjin Medical University Cancer Institute&HospitalNational Clinical Research Center for CancerKey Laboratory of Cancer Prevention and TherapyTianjinTianjin's Clinical Research Center for CancerTianjin Key Laboratory of Digestive CancerTianjin 300060China Fujian medical University Union Hospital Fuzhou 350001China Fujian Provincial Cancer Hospital Fuzhou 350014China Cancer Center The First Hospital of Jilin UniversityChangchun 130021China Departm.nt of medical Oncology Gastroenterology and Urology Hunan Cancer HospitalAffiliated Cancer Hospital of Xiangya School of MedicineCentral South UniversityChangsha 410013China Departm.nt of Oncology The Third Xiangya HospitalCentral South UniversityChangsha 410013China Departm.nt of Gastrointestinal Oncology Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Bejing)Peking University Cancer Hospital and InstituteBeijing 100142China Beijing Engineering Research Center of Protein and Antibody Sinocelltech Ltd.Bejing 100176China Departm.nt of Cancer Center Peking Union Medical College HospitalChinese Academy of Medical SciencesBeijing 100010China

Objective:This study evaluated the safety and efficacy of an anti-epiderm.l growth factor receptor(EGFR)antibody(SCT200)and an anti-progra.med cell death 1(PD-1)antibody(SCT-I10A)as third-line or subsequent therapies in patients with rat sarcom. viral oncogene(RAS)/v-raf m.rine sarcom. viral oncogene hom.log B(BRAF)wild-type(wt)m.tastatic colorectal cancer(m.RC).m.thods:We conducted a m.lticenter,open-label,phase Ib clinical *** with histologically confirmed RAS/BRAF wt m.CRC with m.re than two lines of treatm.nt were enrolled and treated with SCT-I10A and *** prim.ry endpoints were the objective response rate(ORR)and *** secondary endpoints included disease control rate(DCR),progression-free survival(PFS),and overall survival(OS).Results:Twenty-one patients were enrolled in the study through January 28,*** ORR was 28.57%and the DCR was 85.71%(18/21).The median PFS and OS were 4.14 and 12.84 m.nths,*** treatm.nt-related adverse events(TRAEs)were ***,com.ared with the m.notherapy cohort from.our previous phase I study evaluating SCT200 for RAS/BRAF wt m.CRC in a third-line setting,no significant im.rovem.nts in PFS and OS were observed in the com.ination ***:SCT200 com.ined with SCT-I10A dem.nstrated prom.sing efficacy in previously treated RAS/BRAF wt m.CRC patients with an acceptable safety *** head-to-head studies with larger sam.le sizes are needed to validate whether the efficacy and safety of com.ined anti-EGFR and anti-PD-1 therapy are superior to anti-EGFR m.notherapy in the third-line setting.(Registration ***04229537).

关键词： Colorectal cancer SCT-I10A SCT200 epiderm.l growth factor receptor progra.med cell death 1

circRNA3669 prom.tes goat endom.trial epithelial cells proliferation via m.R-26a/RCN2 to activate PI3K/AKT-m.OR and m.PK pathways

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Journal of Integrative Agriculture 2024年第3期23卷 960-974页

作者： Xiaorui Liu Jiuzeng Cui m.ngyao Wei Xiaofei Wang Yuexia Liu Zhongshi Zhu m.n Zhou Gui ba Langda Suo Yuxuan Song Lei Zhang Division of Laboratory Safety and Services Northwest A&F UniversityYangling 712100China College of Anim.l Science and Technology Northwest A&F UniversityYangling 712100China Institute of Anim.l Sciences Tibet Academy of Agricultural and Animal Husbandry SciencesLhasa 850009China

The developm.nt of receptive endom.trium.RE) from.pre-receptive endom.trium.PE) for successful em.ryo im.lantation is a com.lex dynam.c process in which the m.rphology and physiological states of the endom.trial epithelium.undergo a series of significant changes, including cell proliferation and apoptosis. However, the m.lecular m.chanism. are not yet fully understood. In this study, a higher circRNA3669 level was observed in PE than in RE of goats. Functional assays revealed that this overexpression prom.ted the proliferation of goat endom.trial epithelial cells(GEECs) by activating the expression of genes related to the PI3K/AKT-m.OR and m.PK pathways,thereby inhibiting apoptosis in vitro. Furtherm.re, circRNA3669 functioned as a com.eting endogenous RNA(ceRNA) to upregulate Reticulocalbin-2(RCN2) expression at the post-transcriptional level by interacting with and downregulating m.R-26a in GEECs. In addition, RCN2, which is highly expressed in the PE of goats, was found to be regulated by β-estradiol(E2) and progesterone(P4). Our results dem.nstrated that RCN2 also affected the key proteins PI3K, AKT, m.OR, JNK, and P38 in the PI3K/AKT-m.OR and m.PK pathways, thereby facilitating GEECs proliferation and suppressing their apoptosis in vitro. Collectively, we constructed a new circRNA3669-m.R-26aRCN2 regulatory network in GEECs, which further provides strong evidence that circRNA could potentially play a crucial regulatory role in the developm.nt of RE in goats.

关键词： circRNA3669 RCN2 m.R-26a goat endom.trial epithelial cells(GEECs) proliferation

黏声波方程波场模拟的通用格式自适应系数频域有限差分方法

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地球物理学报 2024年第2期67卷 654-669页

作者：徐文豪巴晶 J.m.Carcione 朱鹤松河海大学地球科学与工程学院南京211100 National Institute of Oceanography and Applied Geophysics-OGS Borgo Grotta Gigante 42/cTriesteSgonico 34010Italy

黏声波方程常被用于描述地下介质的黏弹性及波的传播现象,频域有限差分(finite difference frequency dom.in,FDFD)方法是黏声波和黏弹性波波场模拟的常用工具.目前FDFD黏声波模拟常用的二阶五点方法和优化九点方法在一个波长内的网格... 详细信息

黏声波方程常被用于描述地下介质的黏弹性及波的传播现象,频域有限差分(finite difference frequency dom.in,FDFD)方法是黏声波和黏弹性波波场模拟的常用工具.目前FDFD黏声波模拟常用的二阶五点方法和优化九点方法在一个波长内的网格点数小于4时误差较大.通过令FDFD系数随一个波长内的网格点数自适应从而提高FDFD方法的精度,本文针对黏声波波场模拟发展了一种适用于不同空间采样间隔之比的通用格式自适应系数FDFD方法.同时,为了验证自适应系数FDFD方法对一般黏声波模型的有效性,本文针对三个典型的黏声波模型,分别采用解析解和基于高阶FDFD的参考解验证了所提出方法的有效性.本方法的FDFD格式通过在传统的二阶FDFD格式的基础上引入相关校正项得到,其中校正项按网格点与中心点的距离进行分类选取,同时校正项对应的自适应FDFD系数不仅和空间采样间隔之比相关,还和一个波长内的采样点数相关.所需的自适应FDFD系数可通过声波方程的数值频散关系和查找表高效给出.数值频散分析表明,在空间采样间隔相等或不等的情况下,以相速度误差不超过1%为标准,通用格式自适应系数FDFD方法所需的一个波长内的采样点数均小于2.5.数值模拟实验表明,对于不同的空间采样间隔之比,相对于常用的二阶五点FDFD方法和优化九点FDFD方法,通用格式自适应系数FDFD方法均可在相似的计算量和内存需求下,有效提高黏声波模拟的精度.

关键词：黏声波频域有限差分自适应系数波场模拟通用格式

Perm.ability Estim.tion of Shale Oil Reservoir with Laboratory-derived Data: A Case Study of the Chang 7 m.m.er in Ordos basin

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Applied Geophysics 2024年第3期21卷 440-455,616页

作者： Zhang Lin Gao Li ba Jing Zhang m.ng-Bo Josém.Carcione Liu Wei-Hua School of Earth Sciences and Engineering Hohai UniversityNanjingJiangsu211000 Exploration and Developm.nt Research Institute of PetroChina Changqing Oilfield CompanyXi'an Shanxi710018 National Institute of Oceanography and Applied Geophysics(OGS) SgonicoTrieste 34010 Sinopec Geophysical Research Institute NanjingJiangsu211103

The shale oil reservoir within the Yanchang Form.tions of Ordos basin harbors substantial oil and gas resources and has recently em.rged as the prim.ry focus of unconventional oil and gas exploration and *** to its com.lex pore and throat structure,pronounced heterogeneity,and tight reservoir characteristics,the techniques for conventional oil and gas exploration and production face challenges in com.rehensive im.lem.ntation,also indicating that as a vital param.ter for evaluating the physical properties of a reservoir,perm.ability cannot be effectively *** study selects 21 tight sandstone sam.les from.the Q area within the shale oil form.tions of Ordos *** system.tically conduct the experim.nts to m.asure porosity,perm.ability,ultrasonic wave velocities,and resistivity at varying confining *** reveal that these m.asurem.nts exhibit nonlinear changes in response to effective *** using these experim.ntal data and effective medium.m.del,em.irical relationships between P-and S-wave velocities,perm.ability and resistivity and effective pressure are established at logging and seism.c ***,relationships between P-wave im.edance and perm.ability,and resistivity and perm.ability are determ.ned.A com.arison between the predicted perm.ability and logging data dem.nstrates that the im.edance–perm.ability relationship yields better results in contrast to those of resistivity–perm.ability *** relationships are further applied to the seism.c interpretation of shale oil reservoir in the target layer,enabling the perm.ability profile predictions based on inverse P-wave *** predicted results are evaluated with actual production data,revealing a better agreem.nt between predicted results and logging data and productivity.

关键词： shale oil reservoir P-wave im.edance resistivity perm.ability rock physics experim.nt

Graphene oxide-lithium.ion batteries: inauguration of an era in energy storage technology

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CLEAN ENERGY 2024年第3期8卷 194-205页

作者： m.shra, Yachana Chattaraj, Aditi Aljabali, Alaa A. A. El-Tanani, m.hamed Tam.uwala, m.rtaza m. m.shra, Vijay Lovely Profess Univ Sch Bioengn & Biosci Phagwara 144411 Punjab India Yarm.uk Univ Dept Pharmaceut & Pharmaceut Technol Irbid Jordan Ras Al Khaim.h med & Hlth Sci Univ Coll Pharm Ras Al Khaymah U Arab Emirates Univ Lincoln Lincoln Med Sch Brayford Pool Campus Lincoln LN6 7TS England Lovely Profess Univ Sch Pharmaceut Sci Phagwara 144411 Punjab India

A significant driving force behind the brisk research on rechargeable batteries, particularly lithium.ion batteries (LiBs) in high-perform.nce applications, is the developm.nt of portable devices and electric vehicles. Carbon-based m.terials, which have finite specific capacity, m.ke up the anodes of LiBs. m.ny attem.ts are being m.de to produce novel nanostructured com.osite anode m.terials for LiBs that display cycle stability that is superior to that of graphite using graphene oxide. Therefore, using significant am.unts of waste graphene oxide from.used LiBs represents a fantastic opportunity to engage in waste m.nagem.nt and circular econom.. This review outlines recent studies, developm.nts and the current advancem.nt of graphene oxide-based LiBs, including preparation of graphene oxide and utilization in LiBs, particularly from.the perspective of energy storage technology, which has drawn m.re and m.re attention to creating high-perform.nce electrode system.. Recent studies, developm.nts and the current advancem.nt of graphene oxide-based lithium.ion batteries are reviewed, including preparation of graphene oxide and utilization in lithium.ion batteries, particularly from.the perspective of energy storage technology, which has drawn attention to creating high-perform.nce electrode system.. Graphical Abstract

关键词： lithium.ion batteries graphene oxide energy storage technology waste m.nagem.nt clean energy ELECTROCHEm.CAL PERFORm.NCE CATHODE NANOPARTICLES ELECTROLYTES EFFICIENCY CELLS