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A novel method for the synthesis of carba-DHPG and carba-ACV

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Chinese Journal of Chemistry 1991年第6期9卷 536-542页

作者： LIU Yu-Gang FEI Chang-Pei CHEN te-Heng CHAN ta-Hang Institute of Chemistry The Chinese Academy of SciencesBeijing 100080 Department of Chemistry McGill University MontrealPQCanada

A new and efficient method for the synthesis of potential antiviral agents Carba-ACV (3) and Carba-DHPG (4) is described. The synthesis makes the use of N- acetylguanine to condense with the corresponding tosylates (16) and (11) under the catalysis of dibenzo-18-C-6, resulting in the desired coupling products (17) and (12) in good yield and in the case of Carba-DHPG with high regioselecti- vity.

关键词： A novel method for the synthesis of carba-DHPG and carba-ACV

Prognosis and feasibility of en-bloc vascular resection in stage Ⅱ pancreatic adenocarcinoma

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World Journal of Gastroenterology 2010年第8期16卷 997-1002页

作者： K Dilip Chakravarty Jun-te Hsu Chun-Nan Yeh ta-Sen Yeh Tsann-Long Hwang Miin-Fu Chen Department of General Surgery Chang Gung Memorial Hospital

AIM:To establish the prognosis and feasibility of en-bloc vascular resection of stage pancreatic adenocarcinoma of the head and uncinate ***:We retrospectively analyzed 87 patients with stage pancreatic adenocarcinoma,who were subjected to pancreaticoduodenectomy (PD) and pylo-rus-preserving PD (PPPD) between 1996 and 2006 in Chang Gung Memorial Hospital,taiwan. Twelve and 75 patients underwent PD/PPPD with and without resection of portal vein/superior mesenteric vein (PV/SMV),***:The overall 1-and 3-year survival rates of patients undergoing PD/PPPD with and without vas-cular resection were 50.0% and 16.7%,and 44.4% and 12.2%,respectively. Morbidity and mortality rates in the PV/SMV resection vs non-resection group were 50.0% and 0.0%,and 40.0% and 2.7%,respectively. In multivariate analysis,serum bilirubin,histological differentiation and adjuvant chemotherapy were independent prognostic factors that influenced ***:In stage adenocarcinoma of the pancreatic head and uncinate process,serum bilirubin,histological differentiation and adjuvant chemotherapy were independent prognostic factors,and en-bloc vascular resection is a feasible option in carefully selected patients.

关键词： Pancreatic neoplasms Adenocarcinoma Portal vein Superior mesenteric vein Pancreaticoduo-denectomy Chemotherapy

Research of Mechanical and Thermal Properties of Composite Material Based on Gypsum and Straw

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Journal of Renewable Materials 2022年第7期10卷 1859-1873页

作者： Nikola Vavřínová Kateřina Stejskalová Jiříteslík Kateřina Kubenková JiříMajer Faculty of Civil Engineering VSB-Technical University of OstravaOstrava70800Czech Republic

This article is focused on the investigation of the mechanical and thermal properties of composite material that could be used for the production of plaster or *** composite material is made of gypsum and reinforcing natural *** article verifies whether this natural reinforcement can improve the investigated properties compared to conventional plasters and gypsum plasterboards made of pure *** this composite material,high-strength plasterboards could then be produced,which meet the higher demands of users than conventional gypsum *** their production,natural waste materials would be used *** part of the development of new building materials,it is necessary to specify essential characteristics for their later use in civil *** wheat straw and three gypsum classes with strengths G2(2 MPa)—gypsum Class I.,G5(5 MPa)—gypsum Class *** G16(16 MPa)—gypsum Class *** used to create the test *** were made with different ratios of the two ingredients,with the percentages of straw being 0%,2.5%,and 5%for each gypsum *** first part of the article describes how the increasing proportion of straw affects the composite’s mechanical properties(flexural strength and compressive strength).The second part of the article focuses on the change of thermal properties(thermal conductivity and specific heat capacity).The last part of the article mentions the verification of the fire properties(single-flame source fire test and gross heat of combustion)of this composite *** research has shown that the increasing proportion of straw reinforcement caused a deterioration in the flexural strength(up to 56.49%in the *** of gypsum Class II.)and compressive strength(up to 80.27%in the *** of gypsum Class III.)and an improvement in the specific heat capacity and thermal conductivity(up to 31.40%in the ***).This composite material is thus not suitable for the production of high-streng

关键词： Composite material gypsum plasterboard crushed straw flexural strength compressive strength thermal conductivity specific heat capacity ignitability gross heat of combustion

Predictive factors for lymph node metastasis in early gastric cancer

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World Journal of Gastroenterology 2010年第41期16卷 5252-5256页

作者： Chang-Mu Sung Chen-Ming Hsu Jun-te Hsu ta-Sen Yeh Chun-Jung Lin Tse-Ching Chen Cheng-tang Chiu Department of Gastroenterologyand Hepatology Chang Gung Memorial Hospital College of Medicine Chang Gung University Department of Surgery Chang Gung Memorial Hospital Chang Gung University Department of Pathology Chang Gung Me-morial Hospital Chang Gung University

AIM: To analyze the predictive factors for lymph node metastasis (LNM) in early gastric cancer (EGC). METHODS: Data from patients surgically treated for gastric cancers between January 1994 and December 2007 were retrospectively collected. Clinicopathological factors were analyzed to identify predictive factors for LNM. RESULTS: Of the 2936 patients who underwent gas-trectomy and lymph node dissection, 556 were diag-nosed with EGC and included in this study. Among these, 4.1% of patients had mucosal tumors (T1a) with LNM while 24.3% of patients had submucosal tumorswith LNM. Univariate analysis found that female gen-der, tumors ≥ 2 cm, tumor invasion to the submucosa, vascular and lymphatic involvement were significantly associated with a higher rate of LNM. On multivariate analysis, tumor size, lymphatic involvement, and tumor with submucosal invasion were associated with LNM. CONCLUSION: Tumor with submucosal invasion, size ≥ 2 cm, and presence of lymphatic involvement are predictive factors for LNM in EGC.

关键词： Early gastric cancer Lymph node metasta-sis Endoscopic treatment Endoscopic submucosa dis-section Depth of tumor invasion

Rolling route for refining grains of super light Mg-Li alloys containing Sc and Be

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Transactions of Nonferrous Metals Society of China 2010年第8期20卷 1374-1379页

作者： CHIANG Chih-te LEE Shyong Department of Mechanical Engineering National Central University

Pioneering work on Sc or/and Be added Mg-Li alloys with refined grains was initiated. Various rolling-based thermo-mechanical treatments on these Mg-Li alloys were carried out. Four Mg-Li alloys were prepared by vacuum melting process. A unique route for producing fine grains was applied which concluded solution treatment at 350 ℃, cold rolling with 60% thickness reduction and 250 ℃ annealing, successively.

关键词： Mg-Li alloy beryllium scandium solid solution strengthening

Compaction-induced stress in geosynthetic-reinforced granular base course--A discrete element model

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Journal of Rock Mechanics and Geotechnical Engineering 2018年第4期10卷 669-677页

作者： te Pei Xiaoming Yang School of Civil and Environmental Engineering Oklahoma State UniversityStillwaterUSA

A discrete element method(DEM) model was used to simulate the development of compaction-induced stress in a granular base course, with and without geogrid reinforcement. The granular base course was modeled as a mixture of uniformly sized triangular particles. The geogrid was modeled as a series of equally spaced balls that interact with each other through long-range interaction contacts. The longrange interaction contact was also used to simulate a deformable subgrade. The compactor was modeled as a solid cylinder rolling at a constant speed. The DEM model shows that the geogridreinforced granular base course gains additional compaction-induced stress due to the residual tensile stress developed in the geogrid. The residual tensile stress in the geogrid increases with the number of compaction passes. Parametric analyses were also conducted to assess the effects of geogrid stiffness and subgrade modulus on the compaction-induced stress.

关键词： Compaction Geosynthetics Granular soils Numerical analysis

Variational Calculation of Lattice SU(N) Gauge System

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Chinese Physics Letters 1996年第5期13卷 337-339页

作者： ZHENG Xi-te Shahram Alavian Department of Applied Physics Sichuan Union University(Chengdu University of Science and Technology)Chengdu 610065 Saskatchewan Accelerator Laboratory University of SaskatchewanSaskatoonSaskatchewanCanadaS7N5C6(present address)

A general method for an analytical calculation of SU(N)lattice gauge theories with finite N≥3 *** an example,the order parameter(E)of lattice SU(4)gauge systetn is *** result is in good agree^nent with Monte Carlo si... 详细信息

关键词： gauge lattice finite

Large time behaviour for the Fokker-Planck equation with general potential

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Science China Mathematics 2018年第1期61卷 137-150页

作者： te Li Zhifei Zhang School of Mathematical Sciences Peking University

In this paper, we study the large time behaviour of the solution of the Fokker-Planck equation with general potential. For the long range potential, we prove the polynomial decay estimate in time of the solution. For ... 详细信息

关键词： Fokker-Planck equation large time behavior hypocoercivity method

Nanomaterials incorporated ultrasound contrast agents for cancer theranostics

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Cancer Biology & Medicine 2016年第3期13卷 313-324页

作者： Lei Fu Heng-te Ke College of Pharmaceutical Sciences Soochow University Center of Systems Medicine Chinese Academy of Medical Sciences Suzhou Institute of Systems Medicine

Nanotechnology provides various nanomaterials with tremendous functionalities for cancer diagnostics and ***, theranostics has been developed as an alternative strategy for efficient cancer treatment through combination of imaging diagnosis and therapeutic interventions under the guidance of diagnostic results. Ultrasound(US) imaging shows unique advantages with excellent features of real-time imaging, low cost, high safety and portability, making US contrast agents(UCAs)an ideal platform for construction of cancer theranostic agents. This review focuses on the development of nanomaterials incorporated multifunctional UCAs serving as theranostic agents for cancer diagnostics and therapeutics, via conjugation of superparamagnetic iron oxide nanoparticles(SPIOs), Cu S nanoparticles, DNA, si RNA, gold nanoparticles(GNPs), gold nanorods(GNRs), gold nanoshell(GNS), graphene oxides(GOs), polypyrrole(PPy) nanocapsules, Prussian blue(PB) nanoparticles and so on to different types of UCAs. The cancer treatment could be more effectively and accurately carried out under the guidance and monitoring with the help of the achieved theranostic agents. Furthermore, nanomaterials incorporated theranostic agents based on UCAs can be designed and constructed by demand for personalized and accurate treatment of cancer, demonstrating their great potential to address the challenges of cancer heterogeneity and adaptation, which can provide alternative strategies for cancer diagnosis and therapeutics.

关键词： Cancer theranostics ultrasound contrast agents nanomaterials nanomedicine