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Risk factors for carotid plaque progression after optimising the risk factor treatment: substudy results of the Atherosclerotic Plaque Characteristics Associated with a Progression Rate of the Plaque and a Risk of Stroke in Patients with the carotid Bifurcation Plaque Study (ANTIQUE)

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Stroke & Vascular Neurology 2022年第2期7卷 132-139页

作者： David Školoudik Petra Kešnerova Tomaš Hrbač David Netuka Jaroslav Vomačka kateřina Langova Roman Herzig Tomaš Belšan Center for Health Research Faculty of MedicineUniversity of OstravaOstravaCzech Republic Department of Neurology University Hospital OstravaOstravaCzech Republic Department of Neurology Second Faculty of MedicineCharles UniversityPrahaCzech Republic Department of Neurology Motol University HospitalPrahaCzech Republic Department of Neurosurgery Faculty of MedicineUniversity of OstravaOstravaCzech Republic Department of Neurosurgery University Hospital OstravaOstravaCzech Republic Department of Neurosurgery Military University Hospital PraguePrahaCzech Republic Department of Radiological Assistance Faculty of Health SciencesPalacky University OlomoucOlomoucCzech Republic Deaprtment of Radiology University Hospital OlomoucOlomoucCzech Republic Department of Biophysics Faculty of MedicinePalacky University OlomoucOlomoucCzech Republic Department of Neurology University Hospital Hradec KrálovéHradec KraloveCzech Republic Department of Neurology Faculty of Medicine in Hradec KrálovéCharles UniversityHradec KrálovéCzech Republic Department of Radiology Military University Hospital PraguePrahaCzech Republic

background and aim Carotid plaque progression contributes to increasing stroke *** study aims to identify factors influencing carotid plaque thickness progression after changing the preventive treatment to the‘treating arteries instead of risk factors’strategy,that is,change in treatment depending on the progression of *** The study participants who completed sonographic controls over the course of 3 years were enrolled to the *** sonography of cervical arteries was performed in 6-month intervals with measurement of carotid plaque *** thickness measurement error(σ)was set as 3 *** evidently stable and progressive plaques(defined as plaque thickness difference between initial and final measurements of˂σand>2σ,respectively)were included to *** and multivariate logistic regression analysis was performed to identify factors influencing plaque *** A total of 1391 patients(466 males,age 67.2±9.2 years)were enrolled in the *** plaque in at least one carotid artery was detected in 255(18.3%)*** age,male sex,greater plaque thickness,coronary heart disease,vascular surgery/stenting history and smoking were more frequently present in patients with progressive plaque(p˂0.05 in all cases).Multivariate logistic regression analysis identified only the plaque thickness(OR 1.850 for left side,95%CI 1.398 to 2.449;and OR 1.376 for right side,95%CI 1.070 to 1.770)as an independent factor influencing plaque *** Carotid plaque thickness corresponding to stenosis severity is the only independent risk factor for plaque thickness progression after optimising the prevention treatment.

关键词： prevention treatment Duplex

Resin infiltration of deproteinised natural occlusal subsurface lesions improves initial quality of fissure sealing

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International Journal of Oral Science 2017年第2期9卷 117-124页

作者： Andrej M Kielbassa ina Ulrich Rita Schmidl Christoph Schuller Wilhelm Frank Vanessa D Werth Centre for Operative Dentistry Periodontology and Endodontology University of Dental Medicine and Oral Health Danube Private University (DPU) Krems Austria Department of Applied Genetics and Cell Biology UFT-Campus Tulln University of Natural Resources and Life Sciences (BOKU) Vienna Austria Centre for Preclinical Education Department of Biostatistics University of Dental Medicine and Oral Health Danube Private University (DPU) Krems Austria

The aim of this ex vivo study was to evaluate the infiltration capability and rate of microleakage of a low-viscous resin infiltrant combined with a flowable composite resin(RI/CR) when used with deproteinised and etched occlusal subsurface lesions(International Caries Detection and Assessment System code 2). This combined treatment procedure was compared with the exclusive use of flowable composite resin(CR) for fissure sealing. Twenty premolars and 20 molars revealing non-cavitated occlusal carious lesions were randomly divided into two groups and were meticulously cleaned and deproteinised using Na OCl(2%). After etching with HCl(15%), 10 premolar and 10 molar lesions were infiltrated(Icon/DMG; rhodamine B isothiocyanate(RITC)-labelled) followed by fissure sealing(G-?nial Flo/GC; experimental group, RI/CR). In the control group(CR), the carious fissures were only sealed. Specimens were cut perpendicular to the occlusal surface and through the area of the highest demineralisation(DIAGNOdent pen, ka Vo). Using confocal laser-scanning microscopy, the specimens were assessed with regard to the percentage of caries infiltration, marginal adaption and internal integrity. Within the CR group, the carious lesions were not infiltrated. Both premolar(57.9% ± 23.1%) and molar lesions(35.3% ± 22.1%) of the RI/CR group were uniformly infiltrated to a substantial extent, albeit with significant differences(P = 0.034). Moreover, microleakage(n = 1) and the occurrence of voids(n = 2) were reduced in the RI/CR group compared with the CR group(5 and 17 specimens,respectively). The RI/CR approach increases the initial quality of fissure sealing and is recommended for the clinical control of occlusal caries.

关键词： aprismatic enamel fissure sealing occlusal caries resin infiltration sodium hypochlorite

An odyssey through Fitz-Hugh Curtis syndrome

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Journal of Reproduction and Contraception 2015年第3期26卷 173-186页

作者： Ibrahim I BOLAJI ka Yan Shirley SZE Department of Obstetrics and Gynaecology Hull York Medical School (HYMS) Diana Princess of Wales Hospital NLa G NHS Foundation Trust Scartho Road Grimsby DN33 2BA UK

Acute fibrinous perihepatitis due to genital tract infection has attracted sparse and fluctuating interest. The recent increase in the incidence of sexually transmitted disease and the recognition of Chlamydia trachomatis as a causative organism in both pelvic inflammatory disease （PID） and extra pelvic manifestation of PID have brought about the renewed interest in perihepatitis. This is likely to ensure that the clinical features of perihepatitis will now become widely recognised. This paper examines the evolution, clinical features, diagnosis and management of this interesting syndrome and emphasises the need to explore the upper abdomen during laparoscopic gynaecological surgery.

关键词： Fitz-Hugh Curtis syndrome (FHCS) perihepatitis Chlamydia trachomatis pelvic inflammatory disease (PID)

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中日麻将文化杂谈

体育文化导刊 2007年第12期 76-80页

作者：巴卡成都体育学院

麻将具有独特的文化符号的含义,而麻将文化的形成与历史背景和社会变革有着密切的关联。麻将在中国和在日本的发展差异很大,也是一个发人深省的问题,折射出国民性里面的某些东西。文章采用历史研究与文化人类学相结合的方法,立足于麻将... 详细信息

麻将具有独特的文化符号的含义,而麻将文化的形成与历史背景和社会变革有着密切的关联。麻将在中国和在日本的发展差异很大,也是一个发人深省的问题,折射出国民性里面的某些东西。文章采用历史研究与文化人类学相结合的方法,立足于麻将的起源和在日本的传播进行分析论证,并描画出这种古代游戏在如今中国和日本的开展情况。

关键词：中国日本麻将文化

Evaluation of Current Termination of Pregnancy and Related Services at Grimsby(UK) and Recommendations for Service Improvement

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Journal of Reproduction and Contraception 2013年第3期24卷 181-193页

作者： ka Yan Shirley SZE Ibrahim BOLAJI Department of Obstetrics and Gynaecology Hull York Medical School(HYMS)DianaPrincess of Wales HospitalScartho RoadNLAG NHS Foundation TrustGrimsby DN33 2BAEngland

Objective To develop local termination of pregnancy （TOP） dataset and to identify ＂hotspots＂ for highest activity and gaps in our fertility control services. Methods This was a retrospective analysis of 305 women who received TOP under section C of the Abortion Act 1967 over a period of 9 consecutive months from 1st March through to 31st October 2012. Results There were 275 （90.2%） British White （BW） and 30 non-BW women. Among 30 non-BW women, 10 （3.3%） were British Asian, 8 （2.6%） were Polish, 6 （2.0%） were British Black or Black, 5 （1.6%） were Chinese and i （0.3%） was White Latvian. The TOP rate was 8.9% in the under 18 years old and 27.9% in the over 30 years old. Totally 240 TOPs （78. 7%） occurred in 〈10 weeks and 276 TOPs （90.5%） occurred under 13 weeks of gestation. Eight-five women who received TOP-service have had one or more previous termination（s） in the last 3 years. The contraception use was low pre-TOP and none of the women were on long-acting reversible contraception （LARCs） pre- TOP, including those who had repeat terminations. Conclusion There are inequalities and gaps in the TOP and related services in Grimsby which must be addressed to reduce the rate of TOP. This is a major challenge involving multiple agencies. Provision of contraception across all age and ethnic groups, improving sex education, engaging with parents and women to improve their negotiation skills for safer sex, supporting vulnerable women, reducing risk factors e.g. alcohol and substance misuse and raising aspirations across the region will contribute to a reduction in termination rate.

关键词： termination of pregnancy (TOP) contraception long acting reversible contraception (LARC)

Contribution to the Study of Diabetic Kidney Disease in a Sub-Saharan Environment: An Example of the Aristide Le Dantec University Hospital in Dakar

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Open Journal of Nephrology 2023年第4期13卷 339-348页

作者： Ahmed Tall Lemrabott Maria Faye Niakhaleen Keita Seynabou Diagne Moustapha Faye bacary ba Abdou Niang El Hadji Fary ka Nephrology Department Aristide Le Dantec University Hospital Dakar Senegal Nephrology Department Dalal Jamm National Hospital Center Dakar Senegal

Introduction: Diabetic kidney disease (DKD) is a leading cause of chronic kidney disease and dialysis admission. Few studies are available in Sub-Saharan Africa. The objective of this work was to study the epidemiological, clinical, diagnostic and therapeutic characteristics of DKD in our context. Patients and Methods: We conducted an observational, exhaustive and retrospective study focusing on diabetic patients seen in consultation or hospitalized in the Nephrology Department of at the Aristide Le Dantec University Hospital in Dakar during a period of 5 years from January 1, 2017 to December 31, 2021. Results: Of 4735 patients seen during the study period, 491 had DKD, i.e. a hospital prevalence of 10.36%. The average age was 59.1 ± 11.4 years with a sex ratio of 0.95. Type 2 diabetes predominated with 93.4%. The average duration of diabetes was 11.5 ± 7.6 years. Diabetes was associated with high blood pressure in 78.81% of cases, dyslipidemia in 23.2% of cases, active smoking in 6.7% of cases and obesity in 1.6% of cases. Renal failure was the main reason for referral 72.3%. One hundred and forty-eight patients (30.1%) had uncontrolled diabetes. Macroalbuminuria was found in 64.8% and microalbuminuria in 18.7% of cases. One hundred and eighty-five patients (37.7%) were in Stage V of kidney disease and 137 patients were in Stage III (18.1% in Stage IIIb and 9.8% in Stage IIIa). Diabetic nephropathy was the main etiology at 61.30%. Nephropathy was mixed (diabetic and hypertensive) in 18.12 cases. Renin-angiotensin-aldosterone system (RAAS) blockers were prescribed in 83.5% of patients. Conclusion: The different etiologies encountered during the study show the diversity of diabetic kidney disease. Diabetic nephropathy is not the only kidney damage that can occur in diabetics in our context.

关键词： Diabetic Kidney Disease (DKD) Microalbuminuria Diabetic Nephropathy

Conservative Approach Might Be the Strategy by Default in Stable Angina Patients: A Case Report

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World Journal of Cardiovascular Diseases 2020年第11期10卷 769-774页

作者： Serigne Cheikh Tidiane Ndao Mame Madjiguene ka Djibril Marie ba Khadidiatou Dia Mouhamed Chérif Mboup Pape Diadie Fall Department of Cardiology Hospital Principal Dakar Dakar Senegal

Management of stable angina is still a matter of debate. Whether a conservative or invasive approach is better remains unclear. Even though recent large-scale randomized trials depict the conservative strategy as safe and efficient. In this report, we present a case of a 53-year-old male patient with cardiovascular risk factors of hypertension and hypercholesterolemia. He complained about typical chest pain at exertion. The coronary angiogram (CA) revealed severe stenosis of the proximal left anterior descending artery (LAD) ostium. After heart team discussion, coronary artery bypass graft (CABG) was advocated. However, due to a lack of means, the CABG was postponed. Meanwhile, he was managed with guideline-based medical therapy. In addition, he exercised regularly and adopted a healthy diet. Evolution was favorable with excellent symptoms control. A regular follow-up was organized with his cardiologist. A new CA before an eventual CABG six years later showed a significant plaque volume regression of the proximal LAD. We decided to continue conservative management. The stress echocardiogram to assess symptoms and exercise tolerance was normal. Our patient was sent to surgery on top of optimal medical therapy even though angioplasty was a good indication and was feasible. However, while he was struggling to afford the CABG procedure, he adopted a very healthy lifestyle along with medical therapy. Six years later, the result of that approach was without appeal, suggesting and reinforcing the conservative management

关键词： Stable Angina Chronic Coronary Syndrome Conservative Treatment Case Report

Intra-Dialytique Hypotension: Prevalence and Associated Factors in 2 Haemodialysis Centres in Senegal

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Open Journal of Nephrology 2022年第4期12卷 361-368页

作者： ba A. Mamadou Yaya kane Moustapha Faye Ameth Dieng ba bacary Niakhalen Keita babacar Ndiaye Modou Ndongo Sy Abou Maria Faye Ahmed Tall Lemrabott ka E. Fary Department of Nephrology Internal Medicine Faculty of Health Sciences Assane Seck University Ziguinchor Senegal Department of Nephrology ALDH Cheikh Anta Diop University Dakar Senegal

Introduction: This study aimed to assess the prevalence of Intra-dialytic hypotension (IDH) according to the European Best Practice Guidelines (EBPG) definition in relation to the number of haemodialysis sessions and the number of chronic haemodialysis patients and to identify its associated factors. Patients and Methods: We conducted an observational, multicentre and looking-forward study of descriptive and analytical purposes over a 4-week period. The study included all patients with regular chronic haemodialysis with at least two sessions per week and a duration of 180 minutes, who consented to participate in the study and were over 15 years of age. Data collection was done with pre-established forms. The following data were collected: blood pressure before each session, at 30, 60, 120, 180 and 240 minutes of each session;socio-demographic data;dialysis data;clinical, paraclinical, therapeutic data and nursing interventions. Results: The mean age of the patients was 43.84 ± 12.10 years. Among 568 haemodialysis sessions recorded in 50 patients, IDH was noted in 12 haemodialysis sessions, representing a prevalence of 2.11%. Fatigue was found in 5 sessions with IDH episodes (41.66%) followed by yawning (25%), nausea ± vomiting (16.66%) and cramps (16.66%). As nursing interventions, Trendelenburg position and normal saline administration were performed in all IDH episodes. High blood pressure, inter-dialytic weight gain greater than 3 kg, Uf/H > 10 ml/kg/H, anaemia and hypoalbuminaemia were associated with the occurrence of IDH. Conclusion: The prevalence of IDH according to the EBPG definition is low. However, it is an important cause of morbidity and mortality, especially cardiovascular involvement, and the factors associated with its presence have been clearly identified.

关键词： Intra-Dialytic Hypotension Chronic Hemodialysis Patients Dakar Ziguinchor

Late Diagnosis of Takayasu Disease in a 50-Year-Old African Black Woman with Repeated Episodes of Heart Failure: Seeing the Forest through the Trees—A Case Report

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World Journal of Cardiovascular Diseases 2020年第10期10卷 683-697页

作者： Djibril Marie ba Aminata Diack Alain Affangla Serigne Cheikh Tidiane Ndao Madjiguene ka Khadidiatou DIA Mouhamed Cherif Mboup Mouhamed Leye Unit of Research and Training in Medical Sciences University of Thies Thies Senegal Department of Radiology Principal Hospital of Dakar Dakar Senegal Department of Cardiology Principal Hospital of Dakar Dakar Senegal

background: First described in 1908, TAK has now been recognized as a non-specific inflammatory disease of unknown etiology, predominantly affecting young females. Sometimes, it progresses into relatively rare and potentially fatal scenarios such heart failure. Case Presentation: Here, we present the case of a 50-year sub-saharan female suffering from acute heart failure related to TAK. Despite constitutional symptoms (fever, malaise, weight loss) and more characteristic features such claudication of lower extremities, carotydinia, and pulseless syndrome, diagnosis of TAK was delayed since main presentation was heart failure. Immunosuppressive and anticoagulant therapies have induced improvement in cardiac manifestations. Conclusion: Early diagnosis and proper treatment can protect the patient from dangerous complications such heart failure.

关键词： Takayasu Heart Failure Corticotherapy Pulseless Syndrome Sub-Saharan Black Female Case Report