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Journal of Intelligent and Connected Vehicles 2024年第2期7卷 108-128页

作者： Ali Matin Hussein dia Department of Civil and Construction Engineering Swinburne University of TechnologyMelbourne 3122Australia

This study investigates the attitudes and concerns of the Australian public toward connected and autonomous vehicles(CAVs),and the factors influencing their willingness to adopt this *** a comprehensive survey,a diverse group of respondents provided valuable insights toward various CAV scenarios such as riding in a vehicle with no driver,self-driving public transport,self-driving taxis,and heavy vehicles without *** results highlight the significant impact of safety concerns about automated vehicles on individuals’attitudes across all *** levels of concern were associated with more negative attitudes,and a strong correlation between concerns and opposition underlines the necessity of addressing these apprehensions to build public trust and promote CAV ***,nearly 70%of respondents felt uncomfortable driving next to a CAV,but they displayed more confidence in adopting automated public transport in the near ***,around 40%of participants indicated a strong willingness to purchase a CAV,primarily driven by the desire to reduce their carbon footprint and safety ***,respondents with health conditions or disability exhibited heightened interest(almost double those without health conditions)in CAV *** differences emerged in attitudes and preferences toward CAVs,with women expressing a greater level of concern and perceiving higher barriers to CAV *** emphasizes the importance of employing targeted approaches to address the specific concerns of different *** study also underscores the role of trust in technology as a significant barrier to CAV deployment,ranking high among respondents’*** overcome these challenges and facilitate successful CAV deployment,various strategies are suggested,including live demonstrations,dedicated routes for automated public transport,adoption incentives,and addressing liability *** findings from this st

关键词： connected and automated vehicles(CAVs) autonomous vehicles public acceptance stakeholder consultations road safety

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A path planning algorithm for a crop monitoring fixed-wing unmanned aerial system

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Science China(Information Sciences) 2024年第8期67卷 5-23页

作者： longhao QIAN Yi lok lo Hugh Hong-tao LIU Institute of Aerospace Studies University of Toronto Department of Mechanical Engineering The University of Hong Kong

With the growing demand for automation in agriculture, industries increasingly rely on drones to perform crop monitoring and surveillance. In this regard, fixed-wing unmanned aerial systems(UASs)are viable platforms for scanning a large crop field, given their payload capacity and range. To achieve maximum coverage without landing for battery replacement, an algorithm for producing a minimal required energy survey path is essential. Hence, an energy-aware coverage path planning algorithm is proposed *** constraints for a fixed-wing UAS to fly at low altitudes while achieving full coverage of the crop field are first analyzed. Then, the full path is decomposed into straight-line and U-turn primitives. Finally, an algorithm to calculate a combination of straight-line segments and U-turns is proposed to obtain the path with minimum required energy consumption. The genetic algorithm is used to efficiently determine the order of the straight-line paths to traverse. Case studies show that the proposed algorithm can produce planning results for a convex-polygon-shaped crop field.

关键词： path planning genetic algorithm energy minimization fixed-wing UAS aerial survey

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Tau in the pancreas:understanding the link between type 2 diabetes mellitus and Alzheimer's disease

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Signal Transduction and Targeted Therapy 2024年第1期9卷 6-7页

作者： Wenlu Li Steffen Tiedt Eng H.lo Neuroprotection Research Laboratories Departments of Radiology and NeurologyMassachusetts General HospitalHarvard Medical SchoolCharlestownMA02129USA Consortium International pour la Recherche Circadienne sur l’AVC(CIRCA) BostonUSA Institute for Stroke and Dementia Research LMU University HospitalLMU MunichMunichGermany

A recent study published in Molecular Psychiatry proposes a cellular mechanism that may contribute to decreased insulin production in individuals with type 2 diabetes mellitus(T2DM).1 Using a combination of cell culture experiments,animal models and studies in T2DM patients,the authors show that an up-regulation of tau inβ-islet cells can inhibit pancreatic insulin secretion through changes in microtubule assembly.

关键词： T2DM Alzheimer tau

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Fault diagnosis Scheme for Railway Switch Machine Using Multi-Sensor Fusion Tensor Machine

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Computers, Materials & Continua 2024年第6期79卷 4533-4549页

作者： Chen Chen Zhongwei Xu Meng Mei Kai Huang Siu Ming lo School of Electronic and Information Engineering Tongji UniversityShanghai201804China Department of Architecture and Civil Engineering City University of Hong KongHong KongChina School of Computer Engineering Jimei UniversityXiamen361021China

Railway switch machine is essential for maintaining the safety and punctuality of train operations.A data-driven fault diagnosis scheme for railway switch machine using tensor machine and multi-representation monitoring data is developed *** existing methods,this approach takes into account the spatial information of the time series monitoring data,aligning with the domain expertise of on-site manual ***,a multi-sensor fusion tensor machine is designed to improve single signal data’s limitations in insufficient ***,one-dimensional signal data is preprocessed and transformed into two-dimensional ***,the fusion feature tensor is created by utilizing the images of the three-phase current and employing the CANDE-COMP/PARAFAC(CP)decomposition ***,the tensor learning-based model is built using the extracted fusion feature *** developed fault diagnosis scheme is valid with the field three-phase current *** experiment indicates an enhanced performance of the developed fault diagnosis scheme over the current approach,particularly in terms of recall,precision,and F1-score.

关键词： Railway switch machine tensor machine fault diagnosis

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Refill friction stir spot welding (RFSSW): a review of processing, similar/dissimilar materials joining, mechanical properties and fracture mechanism

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Journal of Iron and Steel Research International 2024年第8期31卷 1825-1839页

作者： Yun-qiang Zhao Hao-kun Yang Aloshyn Andriia Hong-hang lo Jia-xin Li Guangdong Provincial Key Laboratory of Advanced Welding Technology China-Ukraine Institute of WeldingGuangdong Academy of SciencesGuangzhou 510000GuangdongChina Smart Manufacturing Division Hong Kong Productivity CouncilHong Kong 999077China E.O.Paton Electric Welding Institute of National Academy of Sciences of Ukraine Kiev 01001KievanUkraine

Refill friction stir spot welding(RFSSW)provides a novel method to join similar and/or dissimilar metallic materials without a key-hole in the center of the *** the key-hole free characterization,the similar/dissimilar RFSSW joint exhibits remarkable and endurable characteristics,including high shear strength,long fatigue life,and strong corrosion *** the meanwhile,as the key-hole free joint has different microstructures compared with conventional friction stir spot welding,thus the RFSSW joint shall possess different shear and fatigue fracture mechanisms,which needs further *** explore the underlying failure mechanism,the similar/dissimilar metallic material joining parameters and pre-treatment,mechanical properties,as well as fracture mechanisms under this novel technology will be *** details,the welding tool design,welding parameters setting,and the influence of processing on the lap shear and fatigue properties,as well as the corrosion resistance will be mainly ***,the roadmap of RFFSW is also discussed.

关键词： Refill friction stir spot welding Processing Mechanism Similar materials joining Dissimilar materials joining Microstructure Mechanical property Fracture mechanism

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Autolysosomal acidification impairment as a mediator for TNFR1 induced neuronal necroptosis in Alzheimer’s disease

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Neural Regeneration Research 2024年第9期19卷 1869-1870页

作者： Evridiki Asimakidou Richard Reynolds Anna M.Barron Chih Hung lo Department of Clinical Neurosciences University of CambridgeCambridgeUK Department of Brain Sciences Faculty of MedicineImperial College LondonLondonUK Lee Kong Chian School of Medicine Nanyang Technological UniversitySingaporeSingapore

Neuronal necroptosis-an emerging form of regulated cell death associated with neuroinflammatory signaling:Alzheimer’s disease(AD)is characterized by the presence of extracellular amyloid-β(Aβ)plaques and intracellular tau neurofibrillary tangles as well as progressive neuronal *** evidence has suggested that prolonged neuroinflammation with increased levels of cytokines,arising from neuronal injury,innate immune responses from glial cells,and peripheral inflammation,leads to neuronal death and AD progression.

关键词： Alzheimer death tau Aβ

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Mathematical Modeling of Cell Polarity Establishment of Budding Yeast

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Communications on Applied Mathematics and Computation 2024年第1期6卷 218-235页

作者： Yue Liu Jun Xie Hay-Oak Park Wing-Cheong lo Department of Mathematics City University of Hong KongTat Chee AvenueKowloonHong KongChina Department of Molecular Genetics The Ohio State UniversityColumbusOHUSA

The budding yeast Saccharomyces cerevisiae is a powerful model system for studying the cell polarity *** cell polarization process is regulated by signaling molecules,which are initially distributed in the cytoplasm and then recruited to a proper location on the cell membrane in response to spatial cues or *** of these signaling molecules involves complex regulation,so the mathematical models become a useful tool to investigate the mechanism behind the *** this review,we discuss how mathematical modeling has shed light on different regulations in the cell *** also propose future applications for the mathematical modeling of cell polarization and morphogenesis.

关键词： Budding yeast Cdc42 Morphogenesis Septin Mathematical models

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How Can Practitioners Support Citizen Volunteers in Disaster Risk Reduction? Insight from “Good and Ready” in Aotearoa New Zealand

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International Journal of Disaster Risk Science 2024年第3期15卷 374-387页

作者： lo?c Le Dé Steve Ronoh Ei Mon Thinn Kyu Brigitte Rive School of Public Health and Interdisciplinary Studies Auckland University of Technology Pacific Health Research Centre Auckland University of Technology New Zealand Red Cross

Global and national policy frameworks emphasize the importance of people's participation and volunteers' role in disaster risk reduction. While research has extensively focused on volunteers in disaster response and recovery, less attention has been paid on how organizations involved in disaster risk management can support volunteers in leading and coordinating communitybased disaster risk reduction. In 2019, the New Zealand Red Cross piloted the Good and Ready initiative in Auckland,Aotearoa New Zealand, with the objective to empower local people in resilience building with a focus on volunteers and community participation. This research examined the positive and negative outcomes of Good and Ready and investigated volunteers' experiences in the disaster resilience initiative. It involved the codesign of a questionnaire-based survey using participatory methods with Good and Ready volunteers, the dissemination of the survey to gather volunteers' viewpoints, and a focus group discussion with participatory activities with Red Cross volunteers. The findings highlight that a key challenge lies in finding a balance between a program that provides flexibility to address contextual issues and fosters communities' ownership, versus a prescriptive and standardized approach that leaves little room for creativity and self-initiative. It pinpoints that supporting volunteers with technical training is critical but that soft skills training such as coordinating, communicating,or facilitating activities at the local level are needed. It concludes that the sustainability of Good and Ready requires understanding and meeting volunteers' motivations and expectations and that enhancing partnerships with local emergency management agencies would strengthen the program.

关键词： Community-based approach Disaster risk reduction New Zealand Participation Volunteers

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检查清单和错误报告系统在提高患者安全和减少医疗差错方面的有效性:叙述性回顾

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International Journal of Nursing Sciences 2024年第3期11卷 387-398页

作者： Emmanuel Aoudi Chance dia Florence Innocent Sardi Abdoul VID Specialized University BergenNorway Universite de Bertoua Cameroon Univerity of Ngaoundere Cameroon

目的探讨检查清单和错误报告系统对医院患者安全和医疗错误的影响。方法系统检索2013-2023年的学术数据库,对符合纳入标准的同行评议研究进行严谨的方法学评估。该综述强调了支持核对表在减少用药错误、手术并发症和其他不良事件方面的... 详细信息

目的探讨检查清单和错误报告系统对医院患者安全和医疗错误的影响。方法系统检索2013-2023年的学术数据库,对符合纳入标准的同行评议研究进行严谨的方法学评估。该综述强调了支持核对表在减少用药错误、手术并发症和其他不良事件方面的有效性证据。错误报告系统提高了透明度,鼓励专业人员报告事件并识别系统漏洞。结果检查表和错误报告系统相互关联,在检查表的实施中强调跨专业合作。文章中使用的不同方法和潜在的发表偏倚可能产生局限性;此外,语言限制可能会排除有价值的非英语研究。虽然积极的影响是显而易见的,但成功取决于组织文化和资源。结论通过查阅相关文献,强调干预措施的重要性,并呼吁进一步研究检查清单和错误报告系统在不同医疗保健和文化背景下的有效性,有助于提高患者安全知识。了解这些动态变化对于医疗保健提供者优化患者安全至关重要。

关键词：患者安全医疗错误检查表错误报告系统健康状况

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Profile of SARS-CoV-2 Infected Patients Hospitalized at the Epidemic Treatment Center (ETC) in Saint-louis, Senegal during the First Two Waves

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Advances in Infectious Diseases 2024年第2期14卷 322-337页

作者： Alassane Dièye Papa Latyr Junior Diouf Bourama Diémé Moustapha Diedhiou diatou dia-Gueye Amadou Diop dia Samba Niang Ibrahima louis Martin Dieng Ameth Dieng Seynabou Lô Ndéye Méry dia-Badiane Health Sciences Training and Research Unit Gaston Berger University Saint-Louis Senegal Emergency Department of Regional Hospital Center Saint-Louis Senegal Department of Infectious and Tropical Diseases of Fann Dakar Senegal

Introduction: The SARS-CoV-2 infection is a major public health emergency. Several risk factors are involved in the occurrence of respiratory distress that can lead to death despite resuscitation measures. Objectives: The aim of this study was to describe the epidemiological, clinical, paraclinical, therapeutic, and evolution profile of patients infected with SARS-CoV-2 hospitalized at the CTE of Saint-louis (Senegal) during the first two waves. Patients and Methods: We conducted a retrospective, cross-sectional, descriptive, and analytical study that included all patients hospitalized at the ETC of Saint-louis (Senegal) with SARS-CoV-2 infection from March 2020 to April 2021. Results: A total of 358 cases were collected, 256 (71.5%) during the first wave and 102 (28.5%) during the second wave. The mean age was 49.5 years (19.5). There was a male predominance (58.4%), with a sex ratio of 1.4. Hypertension was the main comorbidity, with 87 cases (24.3%). The most common functional signs were cough in 194 cases (54.2%), dyspnea in 143 cases (40%) and ageusia in 134 cases (37.4%). Thoracic CT scans were performed on 20 patients (5.6%), with severe involvement (50% - 75%) observed in 50% of cases. Hydroxychloroquine-azithromycin was prescribed to 351 patients (98%). Overall, 338 (94.4%) recovered and 17 (4.7%) died. In multivariate analysis, factors associated with death were male sex [OR = 2.645;95% CI: 1.530 - 4.785;p = 0.011], age 60 years [OR = 1.039;95% CI: 0.564 - 1.914;p = 0.002], the presence of comorbidities [OR = 2.171;95% CI: 0.564 - 3.429;p = 0.033], SpO2 (ambient air) 95% [OR = 2.061;95% CI: 0.616 - 3.827;p = 0.03], acute respiratory distress syndrome (ARDS) [OR = 0.635;95% CI: 0.316 - 1.275;p = 0.001], severe form [OR = 1.664;95% CI: 0.298 - 2.478;p = 0.016], occurrence of complications [OR = 0.521;95% CI: 0.287 - 0.944;p = 0.032], high creatinine levels [OR = 2.061;95% CI: 1.616 - 3.827;p = 0.026], and lymphopenia [OR = 0.485;95% CI: 0.370 - 0.636;p = 0.0

关键词： SARS-CoV-2 Saint-louis Senegal

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