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Hemogram-derived ratios as prognostic markers for major adverse cardiovascular events in patients with non-ST-segment elevation myocardial infarction

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World Journal of Methodology 2025年第2期15卷 125-136页

作者： Emir Bećirović Minela Bećirović SabinaŠegalo Amir Bećirović Semir Hadžić Kenana Ljuca Emsel Papić Lamija Ferhatbegović Malik Ejubović Amira JagodićEjubović a.ila kovčić ArminŠljivo Emir Begagić Department of intensive Care University Clinical Center TuzlaTuzla 75000Bosnia and Herzegovina Department of Nephrology University Clinical Center TuzlaTuzla 75000Bosnia and Herzegovina Department of Laboratory Technologies Faculty of Health SciencesUniversity of SarajevoSarajevo 71000Bosnia and Herzegovina Department of Endocrinology University Clinical Center TuzlaTuzla 75000Bosnia and Herzegovina School of Medicine University of TuzlaTuzla 75000Bosnia and Herzegovina Department for internal Diseases and Hemodialysis Canton Hospital ZenicaZenica 72000Bosnia and Herzegovina Department of internal Medicine Canton Hospital ZenicaZenica 72000Bosnia and Herzegovina Department of Radiotherapy University Clinical Center TuzlaTuzla 75000Bosnia and Herzegovina Department of Cardiology University Clinical Center SarajevoSarajevo 72000Bosnia and Herzegovina Department of General Medicine University of ZenicaSchool of MedicineZenica 72000Bosnia and Herzegovina

BACKGROUND Non-ST segment elevation myocardial infarction(NSTEMi)poses significant challenges in clinical management due to its diverse *** the prognostic role of hematological parameters and derived ratios in NSTEMi patients could aid in risk stratification and improve patient *** To evaluate the predictive value of hemogram-derived ratios for major adverse cardiovascular events(MACE)in NSTEMi patients,potentially improving clinical *** A prospective,observational cohort study was conducted in 2021 at the internal Medicine Clinic of the University Hospital in Tuzla,Bosnia and *** study included 170 patients with NSTEMi,who were divided into a group with MACE and a control group without ***,the MACE group was subdivided into lethal and non-lethal groups for prognostic *** hematological parameters,an additional 13 hematological-derived ratios(HDRs)were monitored,and their prognostic role was *** Hematological parameters did not significantly differ between non-ST segment elevation myocardial infarction(NSTEMi)patients with MACE and a control group at T1 and ***,significant disparities emerged in HDRs among NSTEMi patients with lethal and non-lethal outcomes ***,neutrophil-to-lymphocyte ratio(NLR)and platelet-to-lymphocyte ratio(PLR)were elevated in lethal ***,C-reactive protein-to-lymphocyte ratio(CRP/Ly)at T1(>4.737)demonstrated predictive value[odds ratio(OR):3.690,P=0.024].Both NLR at T1(>4.076)and T2(>4.667)emerged as significant predictors,with NLR at T2 exhibiting the highest diagnostic performance,as indicated by an area under the curve of 0.811(95%Ci:0.727-0.859)and OR of 4.915(95%Ci:1.917-12.602,P=0.001),emphasizing its important role as a prognostic *** This study highlights the significant prognostic value of hemogram-derived indexes in predicting MACE among NSTEMi *** follow-up,NLR,PLR,and CRP/Ly off

关键词： Hemogram-derived ratios Prognostic markers Neutrophil-to-lymphocyte ratio Myocardial infarction

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Arctic sea-ice extent: No record minimum in 2023 or recent years

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Atmospheric and Oceanic Science Letters 2025年第1期18卷 52-55页

作者： Ola M.Johannessen Tor i.Olaussen Nansen Scientific Society BergenNorway Nansen Environmental and Remote Sensing Center BergenNorway

Arctic sea-ice extent reaches its minimum each year in September. On 11 September 2023 the minimum was 4.969 million square kilometers(***^(2)). This was not a record low, which occurred in 2012, when the minimum was 4.175 ***^(2), 0.794 ***^(2) less than the minimum in 2023. However, the ice extent had decreased by 0.432 ***^(2) compared with 2022. Nevertheless, the summer melting in 2023 was remarkably less than expected when considering the strong heat waves in the atmosphere and ocean, with record temperatures set around the world. in general, there is a high correlation between the long-term decrease in sea-ice extent and the increasing CO_(2) in the atmosphere, where the increase of CO_(2) in recent decades explains about 80% of the decrease in sea ice in September, while the remainder is caused by natural variability.

关键词： Sea ice Arctic Minimum ice Climate

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Detection of Chlamydophila psittaci from feral pigeons in environmental samples:problems with currently available techniques

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integrative Zoology 2010年第1期5卷 63-69页

作者： ila GEiGENFEiND Daniel HA AG-WACK ERNAGEL Department of Biomedicine Institute of AnatomyUniversity of BaselBaselSw itzerland

Chlamydophila psittaci(Lillie,1930)Everett et al.,1999,the pathogenic agent of human ornithosis,is widespreadin feral pigeon populations and many cases of transmission from feral pigeons to humans have been *** of the present study was to detect *** in environmental samples to find out more about possibletransmission routes and,therefore,to assess the zoonotic risk for *** samples were collected from nestboxes in a feral pigeon ***,samples were taken from the feather dust film covering the water surface ofpublic fountains where pigeons regularly *** samples were tested for the presence of chlamydial antigenusing an antigen enzyme-linked immunosorbent assay to prove shedding of *** by feral *** testdetects a genus specific lipopolysaccharide in the outer membrane of the chlamydial *** were testedusing the iDEiA PCE Chlamydia Test kit(DakoCytomation)and positive results were verified with iDEiA ChlamydiaBlocking Reagents(DakoCytomation).The iDEiA PCE Chlamydia Test yields a high proportion of positive ***,when iDEiA Chlamydia Blocking was performed,most of the positive results turned out to be negative orcould not be *** conclude that antigen-enzyme-linked immunosorbent assay tests are not suitable fordetecting *** in environmental *** publications where no blocking test was used should bereconsidered critically.

关键词： antigen-enzyme-linked immunosorbent assay Chlamydophila psittaci Columba livia environmen-tal samples zoonosis

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Harmonics in the Squirrel Cage induction Motor Analytic Calculation Part iii: influence on the Torque-speed Characteristic

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CES Transactions on Electrical Machines and Systems 2024年第1期8卷 86-102页

作者： G.kovács the Ganz Electric Works BudapestHungary

The harmonics that appear in the squirrel cage asynchronous machine have been discussed in great detail in the literature for a long time. However, the systematization of the phenomenon is still pending, so we made an attempt to fill this gap in the previous parts of our study by elaborating formulas for calculation of parasitic torques. it was a general demand among those who work in this field towards the author to verify his formulas with measurements. in the literature, it seems,only one detailed, purposeful series of measurements has been published so far, the purpose of which was to investigate the effect of the number of rotor slots on the torque-speed characteristic curve of the machine. The main goal of this study is to verify the correctness of the formulas by comparing them with the referred series of measurements. Relying on this, the expected synchronous parasitic torques were developed for the frequently used rotor slot numbers-as a design guide for the ***, together with our complete table for radial magnetic pull published in our previous work, the designer has all the principles, data and formulas available for the right number of rotor slots for his given machine and for the drive system. This brings this series of papers to an end.

关键词： Asynchronous parasitic torques induction motor Squirrel cage rotor Space harmonics Synchronous parasitic torques

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Harmonics in the Squirrel Cage induction Motor Analytic Calculation-Part Ⅰ: Differential Leakage, Attenuation, Asynchronous Parasitic Torques

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CES Transactions on Electrical Machines and Systems 2023年第4期7卷 320-329页

作者： G.kovács Ganz Electric Works 1095 BudapestHungary

The magnetic field generated in the air gap of the cage asynchronous machine and the harmonics of the magnetomotive forces creating that magnetic field, as well as the related differential leakage, attenuation, asynchronous parasitic torques have been discussed in great detail in the literature, but always separately, for a long time. However, systematization of the phenomenon still awaits. Therefore, it is worth summarizing the completeness of the phenomena in a single study – with a new approach at the same time-in order to reveal the relationships between them. The role of rotor slot number is emphasized much more than before. An existing, commonly used, but still impractical basic figure has been modified to more clearly demonstrate the response of the rotor for the harmonics of the stator. The need to treat differential leakage, asynchronous parasitic torques and attenuation together will be demonstrated: new formula for asynchronous parasitic torque is derived;the long-used characteristic curves for differential leakage and attenuation used separately so far was merged into one, correct curve in order to provide a correct design guide for the engineers.

关键词： Asynchronous parasitic torque Attenuation Differential leakage Squirrel cage induction motor Winding harmonics

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Behaviour of cranes(family Gruidae)mirrors their phylogenetic relationships

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Avian Research 2021年第3期12卷 285-295页

作者： Nela Nováková Jan Robovský Faculty of Science University of South BohemiaBranišovská176037005ČeskéBudějoviceCzechia

Background:The behavioural repertoire of every species evolved over time and its evolution can be traced through the phylogenetic relationships in distinct ***(family Gruidae)represent a small,old,monophyletic group with well-corroborated phylogenetic relationships on the species level,and at the same time they exhibit a complex and well-described behavioural ***:We therefore investigated the evolution of behavioural traits of cranes in a phylogenetic context using several phylogenetic approaches and two types of trait *** cranes exhibit more than a hundred behavioural displays,almost one third of which may be phylogenetically ***:More than half of the analysed traits carry a significant phylogenetic *** ancestor of cranes already exhibited a quite complex behavioural repertoire,which remained unchanged in Balearicinae but altered greatly in Gruinae,specifically by the shedding of traits rather than their *** scoring has an influence on results within the Gruinae,primarily in genera Bugeranus and ***:Albeit the behavioural traits alone cannot be used for resolving species-level relationships within the Gruidae,when optimized on molecular tree,they can help us to detect interesting evolutionary transformations of behaviour repertoire within *** Limpkin(Aramus guarauna)seems to be the most enigmatic species and should be studied in detail for its behavioural repertoire,which may include some precursors of crane behavioural traits.

关键词： Ancestral behavioural repertoire Evolution Phylogenetic signal

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A General Version of the Retract Method for Discrete Equations

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Acta Mathematica Sinica,English Series 2007年第2期23卷 341-348页

作者： Josef DiBLíK irena Rzikov Miroslava RZikov Department of Mathematics Faculty of Electrical Engineering and CommunicationBrno University of TechnologyTechnická 8616 00 BrnoCzech Republic Department of Applied Mathematics Faculty of ScienceCilina UniversityHurbanova 15010 26 CilinaSlovak Republic

We study a problem concerning the compulsory behavior of the solutions of systems of discrete equations u（k ＋ 1） = F（k, u（k））, k ∈ N（a） = {a, a ＋ 1, a ＋ 2 }, a ∈ N,N= {0, 1,... } and F ： N（a） × R^n→R^n. A general principle for the existence of at least one solution with graph staying for every k ∈ N（a） in a previously prescribed domain is formulated. Such solutions are defined by means of the corresponding initial data and their existence is proved by means of retract type approach. For the development of this approach a notion of egress type points lying on the defined boundary of a given domain and with respect to the system considered is utilized. Unlike previous investigations, the boundary can contain points which are not points of egress type, too. Examples are inserted to illustrate the obtained result.

关键词： discrete equation consequent point retract

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Multisensory mechanisms of gait and balance in Parkinson’s disease:an integrative review

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Neural Regeneration Research 2025年第1期20卷 82-92页

作者： Stiven Roytman Rebecca Paalanen Giulia Carli Uros Marusic Prabesh Kanel Teus van Laar Nico i.Bohnen Department of Radiology University of MichiganAnn ArborMIUSA Department of Neurology University of MichiganAnn ArborMIUSA Morris K.Udall Center of Excellence for Parkinson’s Disease Research University of MichiganAnn ArborMIUSA institute for Kinesiology Research Science and Research Centre KoperKoperSlovenia Department of Health Sciences Alma Mater Europaea–ECMMariborSlovenia Parkinson’s Foundation Research Center of Excellence University of MichiganAnn ArborMIUSA Department of Neurology University of GroningenUniversity Medical Center GroningenGroningenThe Netherlands Neurology Service and GRECC VA Ann Arbor Healthcare SystemAnn ArborMIUSA

Understanding the neural underpinning of human gait and balance is one of the most pertinent challenges for 21st-century translational neuroscience due to the profound impact that falls and mobility disturbances have on our aging *** and gait control does not happen automatically,as previously believed,but rather requires continuous involvement of central nervous *** effectively exert control over the body,the brain must integrate multiple streams of sensory information,including visual,vestibular,and somatosensory *** mechanisms which underpin the integration of these multisensory signals are the principal topic of the present *** multisensory integration theories focus on how failure of cognitive processes thought to be involved in multisensory integration leads to falls in older *** emphasis,however,has been placed on specific contributions of individual sensory modalities to multisensory integration processes and cross-modal interactions that occur between the sensory modalities in relation to gait and *** the present work,we review the contributions of somatosensory,visual,and vestibular modalities,along with their multisensory intersections to gait and balance in older adults and patients with Parkinson’s *** also review evidence of vestibular contributions to multisensory temporal binding windows,previously shown to be highly pertinent to fall risk in older ***,we relate multisensory vestibular mechanisms to potential neural substrates,both at the level of neurobiology(concerning positron emission tomography imaging)and at the level of electrophysiology(concerning electroencephalography).We hope that this integrative review,drawing influence across multiple subdisciplines of neuroscience,paves the way for novel research directions and therapeutic neuromodulatory approaches,to improve the lives of older adults and patients with neurodegenerative diseases.

关键词： aging balance encephalography functional magnetic resonance imaging gait multisensory integration Parkinson’s disease positron emission tomography somatosensory vestibular visual

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Apolipoprotein A-i binding protein-mediated neuroprotection in glaucomatous neuroinflammation and neurodegeneration

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Neural Regeneration Research 2025年第5期20卷 1414-1415页

作者： Sinwoo Hwang Seunghwan Choi Soo-Ho Choi Keun-Young Kim Yury i.Miller Won-Kyu Ju Hamilton Glaucoma Center and Shiley Eye institute The Viterbi Family Department of OphthalmologyUniversity of California San DiegoLa JollaCAUSA Department of Medicine University of California San DiegoLa JollaCAUSA National Center for Microscopy and imaging Research Department of NeurosciencesUniversity of California San DiegoLa JollaCAUSA

Glaucoma is a multifactorial eye disorder that can cause vision loss and irreversible blindness,affecting individ uals aged 40 to 80 yea rs *** to the aging population,it is expected that the number of people affected by glaucoma will surpass 111 million by 2040 as the disease becomes more *** primarily contributes to optic nerve axon loss and the progressive degeneration of retinal ganglion cells (RGCs),subsequently leading to vision impairment.

关键词： irreversible pass primarily

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Cavitation and grain boundary sliding during creep of Mg-Y-Nd-Zn-Mn alloy

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中国有色金属学会会刊：英文版 2008年第A1期18卷 64-68页

作者： V.JANíK F.HNiLiCA P.ZUNA V.OENEK i.STULíkov Department of Materials Engineering Faculty of Mechanical EngineeringCzech Technical University in PraguePragueCzech Republic Research institute for Metals Panenské BrezanyCzech Republic Faculty of Mathematics and Physics Charles UniversityPragueCzech Republic

Creep of squeeze-cast Mg-3Y-2Nd-1Zn-1Mn alloy was investigated at the constant load in the stress range of 30-80 MPa. Tensile creep tests were performed at 300℃up to the final *** tests at 50 MPa were interrupted after reaching the steady state creep;and another set of creep tests was interrupted after the onset of ternary *** of cavitated dendritic boundaries was evaluated using optical *** of grain boundary sliding by observation of the offset of marker lines was carried out on the surface of the crept specimens after the test interruption by scanning electron microscopy and by confocal laser scanning *** results show that the dominant creep mechanism in this alloy is dislocation creep with minor contribution of the grain boundary *** failure took place by the nucleation,growth and coalescence of creep cavities on the boundaries predominantly oriented perpendicular to the applied *** amount of cavitated boundaries with time of creep exposure supports the mechanism of continuous cavity nucleation and growth.

关键词：镁合金锌合金锰合金高温测试

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