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Modifiable factors media.ing the effects of educa.ional attainment on gesta.ional diabetes mellitus: A two-step Mendelian randomiza.ion study

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World Journal of Clinical Cases 2024年第26期12卷 5937-5945页

作者： Ming-Yue ma ya-Song Zhao Department of Nursing Shengjing Hospital of China Medical UniversityShenyang 110004Liaoning ProvinceChina

BACKGROUND Although there is currently a wealth of evidence to indicate that maternal educa.ional attainment is associated with gesta.ional diabetes mellitus(GDM),the specific modifiable risk factors that mediate the causal rela.ionship between these two va.iables have yet to be *** To identify the specific modifiable risk factors that mediate the causal rela.ionship between the level of maternal educa.ion and *** Mendelian randomiza.ion(MR)was conducted using data from genome-wide associa.ion studies of European *** initially performed a two-sample MR analysis using data on genetic va.iants associated with the dura.ion of educa.ion as instruments,and subsequently adopted a two-step MR approach using metabolic and lifestyle factors as mediators to exa.ine the mecha.isms underlying the rela.ionship between the level of maternal educa.ion and risk of developing *** addition,we calculated the proportions of total causal effects mediated by identified metabolic and lifestyle *** A genetically predicted higher educa.ional attainment was found to be associated with a lower risk of developing GDM(OR:0.71,95%Ci:0.60-0.84).Among the metabolic factors assessed,four emerged as potential mediators of the educa.ion-GDM associa.ion,which,ranked by mediated proportions,were as follows:waist-to-hip-ra.io(31.56%,95%Ci:12.38%-50.70%),body mass index(19.20%,95%Ci:12.03%-26.42%),high-density lipoprotein cholesterol(12.81%,95%Ci:8.65%-17.05%),and apolipoprotein A-1(7.70%,95%Ci:4.32%-11.05%).These findings proved to be robust to sensitivity *** Our findings indicate a causal rela.ionship between lower levels of maternal educa.ion and the risk of developing GDM can be partly explained by adverse metabolic profiles.

关键词： Educa.ional status Gesta.ional diabetes mellitus Metabolism Lifestyle factors Mendelian randomiza.ion analysis

Chinese Guidelines for the Diagnosis and management of Atrial Fibrilla.ion

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Journal of Geriatric Cardiology 2024年第3期21卷 251-314页

作者： Chang-Sheng ma Shu-Lin WU Shao-Wen LiU ya-Ling HAN Chinese Society of Cardiology Chinese Medical Associa.ion Heart Rhythm Committee of Chinese Society of Biomedical Engineering Beijing Anzhen Hospital Capital Medical University Guandong Provincial People’s Hospital Shanghai First People’s Hospital General Hospital of Northern Theater Command 不详

Atrial fibrilla.ion(AF)is the most common sustained cardiac arrhythmia,significantly impacting pa.ients’qua.ity of life and increa.ing the risk of death,stroke,heart failure,and *** the past two decades,there have been significant breakthroughs in AF risk prediction and screening,stroke prevention,rhythm control,catheter abla.ion,and integrated *** this period,the scale,qua.ity,and experience of AF management in China have greatly improved,providing a solid founda.ion for the development of guidelines for the diagnosis and management of *** further promote standardized AF management,and apply new technologies and concepts to clinical practice in a timely and comprehensive manner,the Chinese Society of Cardiology of the Chinese Medical Associa.ion and the Heart Rhythm Committee of the Chinese Society of Biomedical Engineering have jointly developed the Chinese Guidelines for the Diagnosis and management of Atrial *** guidelines have comprehensively elaborated on va.ious aspects of AF management and proposed the CHA2DS2-VASc-60 stroke risk score based on the characteristics of AF in the a.ian *** guidelines have also reevaluated the clinical applica.ion of AF screening,empha.ized the significance of early rhythm control,and highlighted the central role of catheter abla.ion in rhythm control.

关键词： prevention sustained diagnosis

Systemic inflammatory response index is a predictor of prognosis in gastric cancer pa.ients: Retrospective cohort and meta-analysis

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World Journal of Gastrointestinal Surgery 2024年第2期16卷 382-395页

作者： Jing-yao Ren Meng Xu Xiang-Dong Niu Shi-Xun ma ya-Jun Jiao Da wang Miao Yu Hui Cai School of Clinical Medicine Ningxia Medical UniversityYinchuan 750000Ningxia Hui autonomous regionChina Gansu Provincial Hospital Gansu Provincial HospitalLanzhou 730000Gansu ProvinceChina General Surgery Clinical Medical Center Gansu Provincial HospitalLanzhou 730000Gansu ProvinceChina Medical College of Jiangsu University Jiangsu UniversityZhenjiang 212013Jiangsu ProvinceChina Key Laboratory of Molecular Diagnostics and Precision Medicine for Surgical Oncology in Gansu Province Gansu Provincial HospitalLanzhou 730000Gansu ProvinceChina

BACKGROUND The systemic inflammatory response index(SiRi)has been demonstrated to make a significant difference in assessing the prognosis of pa.ients with different solid ***,research is needed to ascertain the accuracy and relia.ility of applying the SiRi to pa.ients who undergo robotic ra.ical gastric cancer *** To va.idate the applica.ility of the SiRi in assessing the survival of gastric cancer pa.ients and evaluate the clinical contribution of preopera.ive SiRi levels to predicting long-term tumor outcomes in pa.ients,who received robotic ra.ical gastric cancer *** initially,an exhaustive retrieval was performed in the PubMed,the Cochrane Library,EMBASE,Web of Science,and Scopus databases to identify relevant ***,a meta-analysis was executed on 6 cohort studies iden-tifying the value of the SiRi in assessing the survival of gastric cancer ***,the clinical data of 161 pa.ients undergoing robotic ra.ical gastric cancer surgery were retrospectively analyzed to evaluate their clinicopathological characteristics and relevant laboratory *** associa.ion between preopera.ive SiRi levels and 5-year overall survival(OS)and disease-free survival(DFS)was *** The findings demonstrated an extensive connection between SiRi values and the outcome of pa.ients with gastric *** SiRi levels were identified as an independent hazard feature for both OS and DFS among those who received robotic surgery for gastric *** levels in gastric cancer pa.ients were observed to be associated with the presence of comorbidities,T-stage,carcinoembryonic antigen levels,the development of early serious postopera.ive complica.ions,and the rate of lymph node *** SiRi values are correlated with adverse in the gastric cancer popula.ion and have the potential to be utilized in predicting long-term oncological survival in pa.ients who undergo robotic ra.ical gastric canc

关键词： Systemic inflammatory response index Prognosis Gastric cancer Complica.ions Meta-analysis

Uniform decomposition of velocity gra.ient tensor

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Journal of Hydrodyna.ics 2024年第1期36卷 24-34页

作者： Chenxi ma Chaoqun Liu Department of mathema.ics University of Texas at ArlingtonArlingtonTXUSA

in this paper,the principal decomposition of the velocity gra.ient tensor[∇v]is discussed in 3 cases based on the discriminant∆:∆0 with 3 distinct real eigen values,and∆=0 with 1 or 2 distinct real eigen *** velocity ... 详细信息

in this paper,the principal decomposition of the velocity gra.ient tensor[∇v]is discussed in 3 cases based on the discriminant∆:∆ith 1 real eigen value and a pair of conjugate complex eigen values,∆>0 with 3 distinct real eigen values,and∆=0 with 1 or 2 distinct real eigen *** velocity gra.ient tensor can also be classified as rota.ion point,which can be decomposed into three parts,i.e.,rota.ion[R],shear[S]and stretching/compression[SC],and non-rota.ion point,we defined a new resistance term[L],and the tensor can be decomposed into three parts,i.e.,resistance[L],shear[S]and stretching/compression[SC].Example matric are also displayed to demonstrate the new *** of principal decomposition between 3 different cases,and between Resistance and Liutex will also be discussed.

关键词： Velocity gra.ient Liutex resistance fluid kinema.ics

VOC emitted by biopharmaceutical industries:Source profiles,health risks,and secondary pollution

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Journal of Environmental Sciences 2024年第1期135卷 570-584页

作者： Jiawei ma Lin Li State Key Laboratory of Environmental Aqua.ic Chemistry Research Center for Eco-Environmental SciencesChinese Academy of SciencesBeijing 100085China University of Chinese Academy of Sciences Beijing 100049China Na.ional Engineering Laboratory for VOCs Pollution Control material&Technology University of Chinese Academy of SciencesBeijing 101408China

The biopharmaceutical industry contributes substantially to vola.ile orga.ic compounds(VOCs)emissions,causing growing concerns and social developmental *** study conducted an on-site investiga.ion of the process-based emission of VOCs from three biopharmaceutical *** the workshops of the three enterprises,26 VOCs were detected,which could be sorted into 4 classes:hydrocarbons,aroma.ic hydrocarbons,oxygen-containing compounds,and nitrogen-containing *** were the main components of waste gases,accounting for 44.13%-77.85%of the overall ***-based source profiles were compiled for each process unit,with the fermenta.ion and extraction units of tiamulin fumarate being the main source of VOC *** heptanone,vinyl acetate,diethyla.ine,propylene glycol methyl ether(PGME),and benzene were screened as priority pollutants through a fuzzy comprehensive evalua.ion *** level concentra.ion simula.ion results of the Gauss plume diffusion model demonstrated that the diffusivity of VOCs in the atmosphere was rela.ively high,indica.ing potential non-carcinogenic and carcinogenic risks 1.5-2 km ***,the process-based forma.ion potentials of ozone and secondary orga.ic aerosols(SOAs)were determined and indicated that N-methyl-2-pyrrolidone,dimethyl heptanone,and PGME should be preferentially controlled to reduce the ozone forma.ion potential,whereas the control of benzene and chlorobenzene should be prioritized to reduce the genera.ion of *** results provide a ba.is for understanding the characteristics of VOC emission by biopharmaceutical industries and their diffusion,potentially allowing the development of measures to reduce health risks and secondary pollution.

关键词： Biopharmaceutical Vola.ile orga.ic compound Priority pollutant Exposure risk Secondary pollution

Deterministic and Robust Volt-var Control Methods of Power System Based on Convex Deep Learning

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Journal of Modern Power Systems and Clean Energy 2024年第3期12卷 719-729页

作者： Qing ma Changhong Deng the School of Electrical Engineering and Automa.ion Wuhan UniversityWuhanChina

Volt-var control(VVC)is essentially a non-convex optimiza.ion problem due to the non-convexity of power flow(PF)constraints,resulting in the difficulty in obtaining the optimum without convexity *** existing second-order cone method for the convexity conversion often leads to a sharp increase in PF constraints and optimiza.ion va.iables,which in turn increases the optimiza.ion difficulty or even leads to optimiza.ion *** paper first proposes a deterministic VVC method based on convex deep learning power flow(DLPF).This method uses the input convex neural network(iCNN)to establish a single convex mapping between state parameters and node voltage to complete the convexity conversion while the optimiza.ion va.iables only correspond to reactive power equipment,which can ensure the global optimum with extremely fast computa.ion *** cope with the impact brought by the uncertainty of distributed energy and omit the additional worst scena.io search of tra.itional robust VVC,this paper proposes robust VVC method based on convex deep learning interval power flow(DLiPF),which continues to adopt iCNN to establish another convex mapping between state parameters and node voltage *** DLiPF with DLPF,this method decreases the modeling and optimiza.ion difficulty of robust VVC *** results on 30-bus,118-bus,and 200-bus systems prove the correctness and ra.idity of the proposed methods.

关键词： Volt-var control convexity conversion convex deep learning power flow

Copper slag assisted coke reduction of phosphogypsum for sulphur dioxide prepara.ion

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Chinese Journal of Chemical Engineering 2024年第1期65卷 43-53页

作者： Dong ma Qinhui wang State Key Laboratory of Clean Energy Utiliza.ion Institute for Thermal Power EngineeringZhejiang UniversityHangzhou 310027China

The reduction of phosphogypsum(PG)to lime slag and SO_(2)using coke can effectively alleviate the environmental problems caused by ***,the PG decomposition temperature remains high and the product yield remains *** adding additives,the decomposition temperature can be further reduced and PG decomposition rate and product yield can be ***,the use of current additives such as Fe_(2)O_(3)and SiO_(2)brings the problem of increa.ing economic ***,it is proposed to use solid waste copper slag(CS)as a new additive to reduce PG to prepare SO2,which can reduce the cost and meet the environmental benefits at the same *** effects of proportion,temperature and thermosta.ic time on PG decomposition are investigated by experimental and kinetic analysis combined with FactSage thermodyna.ic calcula.ions to optimize the roasting ***,the reaction mecha.ism is *** is found that adding CS to the coke and PG system can increase the rate of PG decomposition and SO_(2)yield while lowering the PG decomposition *** example,when the CS/PG mass ra.io increases from 0 to 1,PG decomposition rate increases from 83.38%to 99.35%,SO_(2)yield increases from 78.62%to 96.81%,and PG decomposition temperature decreases from 992.4℃to 949.6℃.The optimal reaction parameters are CS/PG mass ra.io of 1,Coke/PG mass ra.io of 0.06 at 1100℃for 20 min with 99.35%PG decomposition rate and 96.81%SO_(2) *** process proceeds according to the following reactions:2CaSO_(4)+ 0.7C + 0.8Fe_(2)SiO_(4)→0.8Ca_(2)SiO_(4)+ 0.2Ca_(2)Fe_(2)O_(5)+ 0.4Fe_(3)O_(4)+2SO_(2)+ 0.7CO_(2)Finally,a process for decomposing PG with coke and CS is proposed.

关键词： Phosphogypsum Sulfur dioxide Copper slag Fluidized-bed Reduction waste treatment

A review of recent advances in the effects of surface and interface properties on ma.ine propellers

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Friction 2024年第2期12卷 185-214页

作者： manfu ZHU Liran ma State Key Laboratory of Tribology in Advanced Equipment Tsinghua UniversityBeijing 100084China

Ma.ine propellers are important propulsion devices for both surface ships and underwater *** severe environmental problems have required further performance enhancement for ***,tra.itional methods to improve propeller performances through geometrical and structural optimiza.ions have been extensively investigated,while the underlying mecha.isms of the effects of surface and interface properties on ma.ine propellers are still far from being fully *** paper presented a comprehensive review of recent advances in the effects of surface and interface properties,such as surface roughness and surface wetta.ility,on ma.ine propellers with an empha.is on the significant improvements in both hydrodyna.ic and ca.ita.ion performances,hoping to arouse more in-depth investiga.ions in the field of surface/interface science and technologies on ma.ine propellers,and also promote the state-of-the-art technologies,such as superlubricity technology,into practical applica.ions.

关键词： ma.ine propellers hydrodyna.ics ca.ita.ion surface roughness surface wetta.ility

On the Security of Homomorphic Encryption Schemes with Restricted Decryption Oracles

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Journal of Systems Science & Complexity 2024年第5期37卷 2240-2261页

作者： ma Guangsheng Li Hongbo School of mathema.ics and Physics North China Electric Power University Academy of mathema.ics and Systems Science Chinese Academy of Sciences University of Chinese Academy of Sciences

Fully homomorphic encryption（FHE） can be used for privacy-preserving aggrega.ion of medical data. in this typical applica.ion, the security against passive attacks has been well studied by Li and Micciancio（2021）. in this paper, the authors further consider a “nearly passive” kind of attack, where the attacker may behave like a passive attacker in the view of the third-party *** capture the security against this hard-to-detect attack, the authors propose a new notion of iND-CPArDsecurity. The authors show that the standard LWE encryption and its related FHE schemes can not defend against iND-CPArDattack, even under a stricter rule limiting the content and number of queries made by the attacker. To make the applica.ion of FHE schemes more secure, the authors discuss some possible modifica.ions that may serve as countermeasures to iND-CPArDattack.

关键词： Homomorphic encryption privacy secure cloud computing security