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Chinese Journal of Oceanology and Limnology 2001年第4期19卷 382-388页

作者：朱亚先张勇张杰庄一廷 ka-Fai Poon Michael H.W.Lam 洪华生 Rudolf S.S.Wu Department of Chemistry Xiamen University Environmental Science Research Center the Key Laboratory for Marine Environmental Science of MOE of ChinaXiamen University Environmental Monitoring Center of Fuzhuo City Dept. Bio. Chem. Center for Coastal Pollution and Conservation City Univ. of Hong Kong

A new mimic biological Semi permeable Membrane Device (SPMD) introduced for sampling orga.ic pollutants yielded sa.isfactory results when it was first used as a passive sampler to concentrate and determine 16 kinds of polynuclear aroma.ic hydrocarbons (PAHs) by means of ca.illary GC on an HP 5890 GC FiD in coastal sediment porewater. The concentra.ion of PAHs in sediment porewater for naphthalene(N), acenaphthlene(AL), acenaphthene(AE), fluorene(F), phenaphthene(P), anthracene(A), fluoranthene(FA), pyrene(Py), benzoanthracene(ba), chrysene(Chr), benzofluor anthene(BF), benzofluoranthene(BF), benzopyrene(BP),indeno[1,2,3, cd] Pyrene(iP), dibenzanthracene(DA) and benzo perylene(BP) were: 50.36, under detection limits(UD), 18.19, 8.41, 8.40, 1.44, UD, 8.01, 524.15, 168.47, 50.13, 123.66, 63.48, 27.40, 82.04 and 58,81 ng/L, respectively.

关键词： SPMD monitoring PAHs porewater

Risk Factors for COViD-19 Related Death during the First Three Waves of the Pandemic in an Epidemic Treatment Center at Dakar, Senegal

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Advances in infectious Diseases 2023年第2期13卷 117-131页

作者： Moustapha Diop Papa Samba ba Viviane Ma.ie Pierre Cisse Ndèye Aissatou Lakhe Betty Fall Moustapha Lo Ndong Essomba Bruce Wembulua Fa.imata Wone Becaye Fall Khardiata Diallo-Mbaye Daye ka Louise Fortes Ousmane Faye Ndongo Dia Kha.ifa Ababacar Wade Abdou Rajack Ndiaye Amadou Alpha Sall Moussa Seydi Mame Thierno Dieng Epidemic Treatment Center Dakar Principal Hospital Dakar Senegal infectious and Tropical Diseases Department FANN Teaching Hospital Dakar Senegal Psychiatry Department Dakar Principal Hospital Dakar Senegal internal Medicine Department Deido District Hospital Douala Cameroon Dalal Jamm Hospital Dakar Senegal Federa.ion of Laboratories Dakar Principal Hospital Dakar Senegal Pasteur institute of Dakar Dakar Senegal Anesthesia-Resuscita.ion Department Dakar Principal Hospital Dakar Senegal Dakar Principal Hospital Dakar Senegal

introduction-Objective: COViD-19 is a highly transmissible but often mild viral infection. However, some pa.ients can present severe COViD-19 and subsequently die. The aim of the present study was to assess the risk factors for COViD-19 related death during the first three waves of the disease at the Epidemic Treatment Center (ETC) of Dakar Principal Hospital (DPH). Method: We conducted a descriptive and analytical perspective survival study from April 4, 2020 to September 25, 2021, including adult pa.ients with COViD-19, hospita.ized at the ETC of DPH. Log Rank test and multiva.iate Cox model were performed to identify risk factors for death. Results: We included 556 COViD-19 pa.ients with mean age of 57 ± 17 years and a male-to-female ra.io of 1.26. The number of deaths during one month of follow-up was 41, representing a cumula.ive risk of 7.4%. The log Rank test showed that being from the third wave (p = 0.0056), advanced age (p = 0.00098), presence of at least one comorbidity (p = 0.034), High blood pressure (p = 0.024), d-dimer level ≥ 1000 iU/L (p Conclusion: Our study showed that elderly and third-wave of COViD-19 pa.ients were more at risk to die. Knowledge of risk factors for COViD-19 related death could improve the prognosis of these pa.ients.

关键词： COViD-19 Waves Death Risk Factors Dakar

镁铁质变质火山岩的地球化学——捷克斯洛伐克Zlaté Hory泥盆纪块状硫化物矿床的成因

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世界地质 1989年第2期8卷 54-60页

作者： F.Pato ka 贾大成

ZlateHory块状硫化物矿床区域内的镁铁质变质火山岩被解释为是经受了绿片岩相变质作用的聚合板块边缘的玄武岩和玄武质安山岩。根据主要元素和微量之素组份,这些变质基性岩显示为岛弧拉斑玄武质到低钾、钙—碱性组成。所研究近50％的镁... 详细信息

ZlateHory块状硫化物矿床区域内的镁铁质变质火山岩被解释为是经受了绿片岩相变质作用的聚合板块边缘的玄武岩和玄武质安山岩。根据主要元素和微量之素组份,这些变质基性岩显示为岛弧拉斑玄武质到低钾、钙—碱性组成。所研究近50％的镁铁质变质火山岩样品,在球粒陨石标准化的稀土元素模式中具显著的Ce负异常。Ce衰减绿片岩是岛弧拉斑玄武质组份的变质基性岩热液蚀变表现,蚀变伴有硫化物矿化作用。这从Ce衰减岩石中,ba和S共同富集与Ce/Ce值和CO_2高含量的相互关系得到指示。Ce异常可能由成矿蚀变、海水衍生的溶解作用引起。Ce衰减绿片岩的产生,支持了兹拉特霍尔区域内矿床的火山成因说。

关键词：变质火山岩 Hory Zlat 块状硫化物绿片岩相铁质矿床形成玄武质变质作用聚合板块

Effect of herpesvirus infection on pancrea.ic duct cell secretion

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World Journal of Gastroenterology 2005年第38期11卷 5997-6002页

作者： Péter Hegyi balázs rdg Zoltán Rakonczai Jr Tamás Takács János Lonovics Annamária Szabolcs Réka Sári András Tóth Julius G Papp András Varró Mária K Kovács Mike A Gray barry E Argent Zsolt Boldogki First Department of Medicine Department of Biology Division of Cardiovascular Pharmacology School of Cell and Molecular Biosciences

AiM： To exa.ine the effect of acute infection caused by herpesvirus （pseudora.ies virus, PRV） on pancrea.ic ductal secretion. METHODS： The virulent ba-DupGreen （BDG） and non- virulent ka-RREp01acgfp （KEG） genetically modified strains of PRV were used in this study and both of them contain the gene for green fluorescent protein （GFP）. Small intra/ interlobular ducts were infected with BDG virus （10^7 PFU/mL for 6 h） or with KEG virus （10^10 PFU/mL for 6 h）, while non-infected ducts were incubated only with the culture media. The ducts were then cultured for a further 18 h. The rate of HCO3 secretion [base efflux -λ（B）] was determined from the buffering capa.ity of the cells and the initial rate of intracellular a.idifica.ion （1） after sudden blockage of basolateral base loaders with dihydro-4,4,- diisothiocyanatostilbene-2,2,-disulfonic a.id （500 μmol/L） and a.iloride （200 μmol/L）, and （2） after alka.i loa.ing the ducts by exposure to NH4Cl. All the experiments were performed in HCO3-buffered Ringer solution at 37 ℃ （n = 5 ducts for each experimental condition）. Viral structural proteins were visua.ized by immunohistochemistry. Virallyencoded GFP and immunofluorescence signals were recorded by a confocal laser scanning microscope.RESULTS： The BDG virus infected the majority of accessible cells of the duct as judged by the appearance of GFP and viral anUgens in the ductal cells. KEG virus caused a similarly high efficiency of infection. After blockage of basolateral base loaders, BDG infection significantly elevated -λB-） 24 h after the infection, compared to the non-infected group. However, KEG infection did not modify -λB-）. After alka.i loa.ing the ducts, -λB-） was significantly elevated in the BDG group compared to the control group 24 h after the infection. As we found with the inhibitor stop method, no change was observed in the group KEG compared to the non-infected group. CONCLUSiON： incuba.ion with the BDG or KEG strains of PRV results in an effective i

关键词： Pancreas Hypersecretion Ductal cells infection Pseudora.ies virus

藏族人群下颌第一恒磨牙牙根及根管形态的CBCT研究

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口腔疾病防治 2023年第12期31卷 877-882页

作者：次仁卡卓陈立白玛德吉安生琴卓玛巴央旦增确旦西藏自治区人民医院口腔科西藏自治区拉萨850000 北京大学口腔医学院·口腔医院修复科北京100081

目的应用锥形束计算机体层摄影术(cone⁃beam computed tomography,CBCT),研究分析西藏地区藏族人群的下颌第一恒磨牙的牙根及根管形态,为藏族人群临床根管治疗提供参考。方法本研究已通过单位伦理委员会审查批准,并获得患者知情同意。纳... 详细信息

目的应用锥形束计算机体层摄影术(cone⁃beam computed tomography,CBCT),研究分析西藏地区藏族人群的下颌第一恒磨牙的牙根及根管形态,为藏族人群临床根管治疗提供参考。方法本研究已通过单位伦理委员会审查批准,并获得患者知情同意。纳入300例藏族患者的300颗下颌第一恒磨牙的CBCT影像学资料,记录患者年龄及其下颌第一恒磨牙牙根数目,并用Vertucci分类法统计分析近中牙根及远中牙根根管形态及发生率。结果300颗下颌第一恒磨牙中双根牙198颗;三根牙102颗,三根牙中有1颗存在近中舌根,其余为远中舌根,远中舌根发生率为33.7%(101/300)。近中根最常见根管构型为VertucciⅣ型65.7%(197/300),其次为VertucciⅡ型20.3%(61/300)。近中中央根管(middle mesialcanal,MMC)发生率为6%(18/300),其中20~40岁年龄段发生率最高,为9%(9/100)。远中单根的下颌第一恒磨牙远中根以VertucciⅠ型根管为主,占比66.8%(133/199),其次为VertucciⅡ型14.6%(29/199)和VertucciⅣ型11.6%(23/199);远中为双根的下颌第一恒磨牙,96%(97/101)的远颊根根管和100%(101/101)远舌根根管为VertucciⅠ型。结论藏族人群的下颌第一恒磨牙形态复杂多变,约1/3的患者具有远中舌根,临床医生应在CBCT的指导下仔细探查根管。

关键词：藏族人群下颌第一恒磨牙锥形束计算机体层摄影术近中中央根管远中舌根

Place of Exercise Echocardiography in Stable Coronary Artery Disease in Sub-Saharan Africa:A Series in Senegal

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World Journal of Cardiovascular Diseases 2020年第1期10卷 19-29页

作者： F.Aw M.B.Ndiaye C.M.B.M.Diop S.A.Sarr J.S.Mingou M.T.Diouf M.M.ka M.Ndiaye Ha.iniaina Ravaoavy M.Bodian A.A.Ngaide M.Dioum M.Leye A.Mbaye A.D.kane A.kane M.Diao S.A.ba Cardiology Department Teaching Hospital Aristide Le DantecDakarSenegal Cardiology Department General Hospital of Grand YoffDakarSenegal Cardiology Department Teaching National Hospital of Fann Le DantecDakarSenegal Research and Training Unit of Thies ThiesSenegal Cardiology Department Regional Hospital of Saint LouisSaint LouisSenegal Cardiology Department Dalal Jamm HospitalDakarSenegal

introduction: Exercise echocardiography is a non-inva.ive technique that occupies a special place for the detection of stable coronary disease. The main objective of this study was to report our experience and assess our practice in the diagnosis of stable coronaryartery disease. Methodology: We conducted a retrospective study, descriptive over a period of 34 months, from December 1, 2016 to September 30, 2019. All the pa.ients received during the study period for stress echocardiography as part of a suspicion of stable coronary artery disease were included. A total of 100 exa.ina.ions were completed during the study period. Results: Ninety (90) exams were studied. There were 56 men or a sex-ra.io of 1.64. The mean age was of 57.3 ± 10 years. Hypertension (31 pa.ients or 62%) was the most frequent risk factor. Typical chest pain was noticed in 45 pa.ients (52.3%). The pre-test proba.ility was intermediate in 77 pa.ients (89.5%). Echocardiography at rest was normal in 86 pa.ients (95.6%). A total of 62 tests were nega.ive (69%) and 02 (2.2%) were non-contributory. Ten tests (10) of 26 electrical positive tests were associated with segmental kinetics disorders. in the 10 pa.ients who had exercise kinetic disorders, 08 had coronary angiography. it was normal in 04 of them. The positive predictive value of exercise echography was 50% in our study. in a pa.ient with a nega.ive exercise echocardiography with a high clinical proba.ility of coronary disease, the coronary angiography showed a two-vessel impairment with an intermediate lesion of Cx2 and an intermediate lesion of RCA2. it thus constitutes a false nega.ive. Sensitivity was 80% in our study. We noticed an incident like non-sustained ventricular tachycardia. Conclusion: Exercise echocardiography is a safe and reliable exa.ina.ion for the diagnosis of stable coronary artery disease. A good selection of pa.ients based on the clinical proba.ility of coronary ischemia should improve our sensitivity. This is even more

关键词： Exercise Echocardiography Coronary Artery Disease

牛磺酸对视网膜感光细胞光损伤及NFkB/caspase-1表达的影响

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营养学报 2006年第4期28卷 296-299页

作者：陈卡糜漫天余小平第三军医大学营养与食品卫生学教研室重庆400038

目的:观察牛磺酸对光化学损伤后感光细胞凋亡的影响,并探讨其防护机制。方法:70只SD大鼠随机分为对照组(control),牛磺酸组(taurine,Tau),分别喂饲标准饲料或添加4%Tau饲料15d后接受3000±200lx持续0、1、3、6、9、12、24h光照,用TUNEL... 详细信息

目的:观察牛磺酸对光化学损伤后感光细胞凋亡的影响,并探讨其防护机制。方法:70只SD大鼠随机分为对照组(control),牛磺酸组(taurine,Tau),分别喂饲标准饲料或添加4%Tau饲料15d后接受3000±200lx持续0、1、3、6、9、12、24h光照,用TUNEL法检测感光细胞凋亡并计算凋亡指数(apoptoticindex,Ai),免疫印迹法测定caspase-1和核内p65蛋白表达水平,RT-PCR法检测iκbamRNA。结果:光照9h后Tau组出现凋亡细胞,且多个时相点该组Ai值显著低于对照(PiκbamRNA迅速升高,而Tau组在光照3、6h后升高较显著。视网膜caspase-1蛋白随光照时间延长表达增高,Tau组显著低于对照组对应时相点(P<0.05)。结论:牛磺酸抑制视网膜光化学损伤中感光细胞凋亡,可能与其维持NFκB激活状态进而下调caspase-1表达有关。

关键词：牛磺酸凋亡 NF K B p65 iKba mRNA caspase-1

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基于绿洲环境下的干旱区绿色建筑设计研究

建筑节能（中英文） 2022年第8期50卷 1-7页

作者：喀普兰巴依·艾来提江塞尔江·哈力克新疆大学建筑工程学院乌鲁木齐830047

以2020年国际太阳能十项全能竞赛获奖作品“Solar Ark”为例,通过对该方案的总结与分析,探索干旱区绿色建筑设计方法。该项目拟选址位于新疆吐鲁番吐峪沟村,该地区气候条件独特、生态环境脆弱、人文环境浓郁、历史文化悠久。通过对该地... 详细信息

以2020年国际太阳能十项全能竞赛获奖作品“Solar Ark”为例,通过对该方案的总结与分析,探索干旱区绿色建筑设计方法。该项目拟选址位于新疆吐鲁番吐峪沟村,该地区气候条件独特、生态环境脆弱、人文环境浓郁、历史文化悠久。通过对该地区的调查研究、气候环境的整理、基地环境的分析,从当地传统的建筑空间寻找设计灵感,应用于建筑设计。从技术层面融合被动式和主动式太阳能技术、传统建筑营造技术和新型节能技术的设计方法,满足建筑物的遮阳、防沙、自然通风和室内舒适等问题;利用太阳能光伏板、太阳能集热板与夯土砌块组合墙等技术降低建筑能耗,为当代干旱区的绿洲区域建筑设计给予参考与借鉴。

关键词：太阳能十项全能竞赛绿色建筑地域建筑吐鲁番

基于委托代理理论的第三方回收闭环供应链激励契约机制研究

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商业研究 2016年第1期 183-192页

作者：邢光军池蕴珂 Nankep 南京邮电大学产业信息安全与应急管理研究基地南京210023 南京邮电大学管理学院南京210023

在回收价敏感的回收率条件下,本文考虑包括消费者剩余在内的闭环供应链总利润,建立以独立第三方为回收方的闭环供应链激励模型,分析了TPT-CLSC中激励的引入对环境绩效和经济效益的影响因素,并运用委托代理理论分析TPT-CLSC激励机制设计... 详细信息

在回收价敏感的回收率条件下,本文考虑包括消费者剩余在内的闭环供应链总利润,建立以独立第三方为回收方的闭环供应链激励模型,分析了TPT-CLSC中激励的引入对环境绩效和经济效益的影响因素,并运用委托代理理论分析TPT-CLSC激励机制设计过程中可变激励成本和固定激励成本的影响因素,发现合理的激励机制可以平衡企业环境绩效和经济效益的发展,而闭环激励契约对闭环经济效益的调节受商品残值的影响。

关键词：闭环供应链第三方激励机制委托代理消费者剩余