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Interventional urethral balloon dilatation before endoscopic visual internal urethrotomy for post-traumatic bulbous urethral stricture:A case report

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World Journal of Clinical Cases 2022年第34期10卷 12787-12792页

作者： Ji Yong ha Mu Sook Lee Department of Urology Keimyung University Dongsan HospitalKeimyung University School of MedicineDaegu 42601South Korea Department of Radiology Keimyung University Dongsan HospitalKeimyung University School of MedicineDaegu 42601South Korea

BACKGROUND While several treatment options are available for pediatric urethral strictures,the appropriate treatment must be based on several *** endoscopic visual internal urethrotomy(EVIU)could be a first-line treatment option for short pediatric urethral strictures,it is not feasible if the urethroscope cannot pass through the stricture ***,we present a pediatric case of severe posttraumatic bulbous urethral stricture that was successfully treated by EVIU after securing the urethral route via interventional balloon *** SUMMARY A 12-year-old boy presented at our outpatient clinic with the inability to *** had sustained a straddle injury three months *** post-void residual urine volume was 644 mL,and retrograde urethrography confirmed severe stricture of the bulbous *** was planned;however,the first attempt to treat the stricture failed because the urethroscope could not pass through the stricture *** urethral route was subsequently secured via balloon dilatation of the stricture,which was performed in collaboration with specialists from the department of interventional *** urethroscope was then able to pass,and the repeat EVIU was *** Interventional urethral balloon dilatation before EVIU may help secure the urethral route in the treatment of pediatric urethral strictures.

关键词： Urethral stricture Endoscopic visual internal urethrotomy Urethroplasty Urethral balloon dilatation Interventional radiology Case report

Inhibitory potential of three Yin-tonification herbal formulas on the activities of human major cytochrome P450 and UDP-glucuronosyltransferases isozymes in vitro

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Journal of Traditional Chinese Medicine 2018年第4期38卷 511-522页

作者： Seong Eun Jin Hyeun-Kyoo Shin Hyekyung ha K-herb Research Center Korea Institute of Oriental Medicine Daejeon 34054 Republic of Korea

OBJECTIVE:To investigate the influence of Yin-tonification herbal formulas Jaeumganghwa-tang(Ziyin Jianghuo Tang,JEGHT),Ssanghwa-tang(Shuanghe Tang,SHT) and Yukmijihwang-tang(Liuwei Di huang Tang,YMJHT) on the activities of human major cytochrome P450(CYP450 s) and UDP-glucuronosyltransferases isozymes(UGTs) in ***:The activities of CYP450 s(CYP1 A2,CYP3 A4,CYP2 B6,CYP2 C9,CYP2 C19,CYP2 D6 and CYP2 E1) and UGTs(UGT1 A1,UGT1 A4 and UGT2 B7)were assessed using in vitro fluorescence-and luminescence-based enzyme assays,*** effects of herbal formulas on the activities of CYP450 s and UGTs were presented as IC50 ***:JEGHT showed the potent inhibition of the CYP2 D6 activity,with weak inhibition on the activities of CYP1 A2,CYP2 B6,CYP2 C9,CYP2 C19,CYP2 E1,CYP3 A4,UGT1 A1,UGT1 A4 and UGT2 *** inhibited the activities of CYP1 A2 and CYP2 E1,whereas the negligible inhibition of the activities of CYP2 B6,CYP2 C9,CYP2 C19,CYP2 D6,CYP3 A4,UGT1 A1,UGT1 A4 and UGT2 B7 through SHT was *** inhibited CYP2 E1 activity,with a negligible inhibition on the activities of CYP1 A2,CYP2 B6,CYP2 C9,CYP2 C19,CYP2 D6,CYP3 A4,UGT1 A1,UGT1 A4 and UGT2 ***:These findings provide information about the potential interactions between three Yin-tonification herbal formulas and conventional drugs.

关键词： Yin reinforcing agents CytochromeP-450 enzyme system Uridine diphosphate gluc-uronic acid Transferases Herb-drug interactions

Selective catalytic NO_x reduction on Antimony promoted V_2O_5-Sb/TiO_2 catalyst

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Rare Metals 2006年第Z2期25卷 84-88页

作者： ha Heon Phil CHUNG Soon Hyo OH Young Joo Metal Processing Research Center Korea Institute of Science and Technology Cheongryang Seoul 130-650 Republic of Korea

Quantum chemical calculation was carried out to choose a promoter which can reduce the poisoning of V2O5/TiO2 catalysts by SO2. Several atoms were chosen as candidates and new catalysts were synthesized by impregnation method. The NOx conversion rate was measured at temperatures between 100 and 400 ℃ and poisoning effect was investigated. The most promising candidate promoter, Se, was excluded because of its high vapor pressure. On the other hand, Sb shows best promoting properties. Sb promoted catalyst reaches the maximum NOx conversion rate at 250 ℃. It also shows considerably enhanced resistance to poisoning of V2O5/TiO2 catalysts by SO2.

关键词： De NOx selective catalytic reduction SO2 poisoning low temperature activity

Nature-based Natural-hazard Preparedness:A Cross Section of Categorized Examples

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Journal of Environmental & Earth Sciences 2024年第1期6卷 33-44页

作者： Kyoo-Man ha Faculty of Resilience Rabdan AcademyAbu Dhabi114646UAE

Despite prevailing interests,no rigorous research has been conducted to examine the role of nature in natural-hazard *** systematic review aimed to describe how nature can reduce the impacts of natural hazards during the preparedness *** study focuses on the land,water,and air systems and on three types of stakeholders:international organizations,developed countries,and developing ***,it provides supplementary strategies,such as immediate actions,local engagement,and research and development,that the stakeholders should apply to enhance their nature-based natural-hazard *** suggest integrating costs and benefits analysis,local culture,societal challenges,and environmental justice into the implementation of nature-based ***,this review outlines the framework of nature-based natural-hazard preparedness by discussing the relationship between nature and society.

关键词： Nature-based solutions Costs and benefits Land Integration Society

Effects of Traditional Herbal Formulae on Human CYP450 Isozymes

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Chinese Journal of Integrative Medicine 2017年第1期23卷 62-69页

作者： Seong Eun Jin Hyekyung ha Hyeun-Kyoo Shin K-Herb Research Center Korea Institute of Oriental MedicineDaejeon 34054Republic of Korea

Objective：To assess the effects of traditional herbal formulae Sijunzi Decoction（四君子汤,Sagunja-tang,SJZD）,Siwu Decoction（四物汤,Samul-tang,SWD）,Bawu Decoction（八物汤,Palmul-tang,BWD）and Shiquan Dabu Decoction（十全大补汤,Sipjeondaebo-tang,SDD）on the activities of human cytochrome P450（CYP450）,a drug-metabolizing ***：Herbal formula water extracts were filtered and lyophilized after the powder extracts were dissolved in distilled *** activities of major human CYP450isozymes（CYP3A4,CYP2C19,CYP2D6 and CYP2E1）were measured using in vitro fluorescence-based enzyme *** inhibitory effects of the herbal formulas on the activities of CYP450 were characterized as half maximal inhibition concentration（IC50）***：All the tested herbal formulae inhibited CYP2C19activity（IC50：SJZD,83.28μg/m L;SWD,235.54μg/m L;BWD,166.82μg/m L;SDD,178.19μg/m L）;SJZD（IC50=196.46μg/m L）,SWD（IC50=333.42μg/m L）and SDD（IC50=163.42μg/m L）inhibited CYP2E1-mediated metabolism;whereas BWD exhibited comparatively weak inhibition of CYP2E1（IC50=501.78μg/m L）.None of the four herbal formulas significantly affected CYP3A4 or ***：These results suggest that SJZD,SWD,BWD and SDD could potentially inhibit the metabolism of co-administered synthetic drugs whose primary route of elimination is via *** addition,clinically relevant pharmacokinetic interactions could occur when SJZD,SWD or SDD is co-administered with drugs metabolized by *** findings provide information for the safety and effective clinical use of these four classic herbal formulas.

关键词： cytochrome P450 Sijunzi Decoction Siwu decoction Bawu Decoction Shiquan Dabu Decoction,herb-drug interactions

Late Cenozoic Sedimentary Evolution of Pagri-Duoqing Co graben, Southern End of Yadong-Gulu Rift, Southern Tibet

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Acta Geologica Sinica(English Edition) 2018年第3期92卷 972-987页

作者： ha Guanghao WU Zhonghai HE Lin WANG Shubing Key Laboratory of Neotectonic Movement & Geohazards Ministry of Natural Resources Institute of Geomechanics Chinese Academy of Geological Sciences Beijing 100081 China Chinese Academy of Geological Sciences Beijing 10003 7 China College of Earth Science and Resources China University of Geosciences Beijing 100083 China

The north trending rifts in southern Tibet represent the E-W extension of the plateau and confirming the initial rifting age is key to the study of mechanics of these rifts. Pagri-Duoqing Co graben is located at southern end of Yadong-Gulu rift, where the late Cenozoic sediments is predominately composed of fluvio-lacustrine and moraine. Based on the sedimentary composition and structures, the fluviolacustrine could be divided into three facies, namely, lacustrine, lacustrine fan delta and alluvial fan. The presence of paleo-currents and conglomerate components and the provenance of the strata around the graben indicate that it was Tethys Himalaya and High Himalaya. Electron spin resonance(ESR) dating and paleo-magnetic dating suggest that the age of the strata ranges from ca. 1.2 Ma to ca. 8 Ma. Optically stimulated luminescence(OSL) dating showed that moraine in the graben mainly developed from around181-109 ka(late Middle Pleistocene). Combining previous data about the Late Cenozoic strata in other basins, it is suggested that 8-15 Ma may be the initial rifting time. Together with sediment distribution and drainage system, the sedimentary evolution of Pagri could be divided into four stages. The graben rifted at around 15-8 Ma due to the eastern graben-boundary fault resulting in the appearance of a *** by a geologically quiet period about 8-2.5 Ma, the paleolake expanded from east to west at around 8-6 Ma reaching its maximum at ca. 6 Ma. Then, the graben was broken at about 2.5 Ma. At last,the development of the glacier separated the graben into two parts that were Pagri and Duoqing Co since the later stages of the Middle Pleistocene. The evolution process suggested that the former three stages were related to the tectonic movement, which determined the basement of the graben, while the last stage may have been influenced by glacial activity caused by climate change.

关键词： north trending rifts initial rifting age Late Cenozoic strata sedimentary evolution OSL ESR and paleomagnetic dating Tibet China

Nonlinear Local Lyapunov Exponent and Quantification of Local Predictability

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Chinese Physics Letters 2008年第5期25卷 1919-1922页

作者：丁瑞强李建平 ha Kyung-Ja State Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics (LASG) Institute of Atmospheric Physics Chinese Academy of Sciences Beijing 100029 Division of Earth Environmental ~System Pusan National University Busan 609- 735 Korea

Nonlinear local Lyapunov exponent （NLLE） is applied to quantitatively determine the local predictability limit of chaotic systems. As an example, we find that the local predictability limit of Henon attractor varies considerably with time, and some underlying phase-spatial structure does not appear. The local predictability limit of initially adjacent points in phase space may be completely different. This will cause difficulties in making the long-time analogue forecast.

关键词： ATMOSPHERIC PREDICTABILITY

Experimental Investigation of Flexible hawkmoth-like Wings on the Wing-wake Interaction in Hovering Flight

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Journal of Bionic Engineering 2018年第1期15卷 139-153页

作者： YeongGyun Ryu Jo Won Chang Joon Chung Dong-ha Kim Department of Aerospace Engineering Ryerson University Toronto Ontario M5B 2K3 Canada Department of Aeronautical Science and Flight Operation Korea Aerospace University 76 Hanggongdaehak-ro Deogyang-gu Goyang-si Gyeonggi-do 10540 Republic of Korea Aerodynamics Group Korean Air R&D Center Daejeon Metropolitan City 34054 Republic of Korea

To study wing-wake interaction for various wing flexibilities, force measurements and digital particle image velocimetry were carried out on flapping hawkmoth-like wings in a water tank. Wing thickness was employed as a design variable for the wing flexi- bility distributions. Abrupt flap-down and phase delay in flexible wings influenced the behaviors of the Leading-Edge Vortex （LEV） and Trailing-Edge Vortex （TEV）, generated by the previous stroke. While the rigid wing exhibited a detached LEV at the end of the stroke, wing with specific flexibilities obtained attached LEVs. The attached LEVs induced a relatively rapid flow toward the wing surface as a result of encountering the TEV, and the flow caused a higher lift peak. On the other hand, the wings with larger wing deformations generated distinctive changes in LEV and TEV behaviors. The flap-down helped the TEV form closer to the wing surface, and it thus caused a downwash rather than wing-wake interaction. Furthermore, the most flexible wing had a newly-formed pair of LEVs above the wing during the wing reversal, thereby being not able to generate the wing-wake interaction. These results help to understand the different vortex structures generated by flexible wings during the wing reversal and the corresponding effects of wing-wake interaction.

关键词： hovering flight flexible hawkmoth wings wing-wake interaction Digital Particle Image Velocimetry (DPIV)

Fuzzy Feedback Control for Electro-Hydraulic Actuators

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Intelligent Automation & Soft Computing 2023年第5期36卷 2441-2456页

作者： Tan Nguyen Van Huy Q.Tran Vinh Xuan ha Cheolkeun ha Phu Huynh Minh School of Engineering-Technology Thu Dau Mot UniversityThu Dau Mot City590000Vietnam Faculty of Engineering-Technology Nguyen Tat Thanh UniversityHo Chi Minh City754000Vietnam Hue Industrial College Hue City530000Vietnam Robotics and Mechatronics Lab University of UlsanUlsan City44610Korea

Electro-hydraulic actuators(Eha)have recently played a signiﬁcant role in modern industrial applications,especially in systems requiring extremely high *** can be explained by Eha’s ability to precisely control the position and force through advanced sensors and innovative control *** of the promising approaches to improve control accuracy for Eha systems is applying classical to modern control algorithms,in which the proportional–inte-gral–derivative(PID)algorithm,fuzzy logic controller,and a hybrid of these methods are popular *** this paper,we developed a novel version of the fuzzy control algorithm and linear feedback control method,namely fuzzy lin-ear feedback control,to improve the control *** achieve the highest performance,weﬁrst designed a mathematical Eha model based on the Matlab/Simulink software packages thanks to the selected parameters,which are similar to a real Eha ***,we respectively applied PID,fuzzy PID(FPID),and fuzzy linear feedback control(FLFC)before comparing them to have a full view of the outstanding advantages of the proposed *** simulation results showed that the proposed FLFC algorithm is approximately 99%and 77%super-ior in performance to the PID and feedback control algorithms,respectively.

关键词： Electro-hydraulic actuator fuzzy PID feedback control