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临床外科杂志 2005年第6期13卷 369-370页

作者：余玲 a.el ghoneimi Y.Aigrain 上海市儿童医院小儿外科巴黎ROBERT DEBRE医院小儿泌尿外科

目的介绍巴黎ROBERT DEBRE医院的小儿外科应用在膀胱镜下输尿管下端开口处注射聚糖酐/透明质酸共聚物治疗(DEFLUX)治疗小儿膀胱输尿管返流的经验.方法选取从2001～2003年,ROBERT DEBRE 医院(巴黎)小儿外科治疗的57个患儿,其中男11例,女4... 详细信息

目的介绍巴黎ROBERT DEBRE医院的小儿外科应用在膀胱镜下输尿管下端开口处注射聚糖酐/透明质酸共聚物治疗(DEFLUX)治疗小儿膀胱输尿管返流的经验.方法选取从2001～2003年,ROBERT DEBRE 医院(巴黎)小儿外科治疗的57个患儿,其中男11例,女46例.平均年龄71个月.患者有急性肾盂肾炎(APN)史,有药物治疗史,并有不同程度的膀胱输尿管返流.共80侧返流的输尿管,行膀胱镜下输尿管开口处注射DEFLUX.结果治疗的患儿术后1年随访.未发现明显的并发症.被治愈的输尿管共58侧(72.5%),1年内未有尿路感染的45例(78.9%).Ⅰ度返流治愈率82.5%.Ⅱ度返流治愈率75.9%.Ⅲ度返流治愈率68.7%.Ⅳ度返流治愈率0.结论在膀胱镜下输尿管下端注射DEFLUX来治疗小儿膀胱输尿管返流,从而控制因膀胱输尿管返流引起的尿路感染是有效的,且安全和简单.

关键词：内窥镜术膀胱输尿管返流儿童

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Evaluating pediatric ureteropelvic junction obstruction:Dynamic magnetic resonance urography vs renal scintigraphy 99mtechnetium mercaptoacetyltriglycine

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World Journal of Radiology 2024年第3期16卷 49-57页

作者： Yousuf Al-Shaqsi Matthieu Peycelon Anna.el Paye-Jaouen elisabeth Carricaburu Anca Tanase Christine Grapin-Dagorno Alaa.el-ghoneimi Department of Pediatric Surgery Sultan Qaboos University HospitalMuscat 123Oman Service de Chirurgie Viscérale et Urologie Pédiatrique Hôpital Universitaire Robert-DebréAssistance-Publique Hôpitaux de ParisParis 75019France Centre de Références Maladies Rares Malformations Rares des Voies Urinaires(MARVU)Paris 97019France Facultéde Médecine Universitéde ParisParis 75006France Service d’Imagerie Pédiatrique Hôpital Universitaire Robert-DebréAssistance-Publique Hôpitaux de ParisParis 75019France UniversitéParis 13 Sorbonne Paris CitéParis 75013France

BACKGROUND Ureteropelvic junction obstruction(UPJO)is a common congenital urinary tract disorder in *** can be diagnosed as early as in utero due to the presence of hydronephrosis or later in life due to symptomatic *** To evaluate the discrepancy between dynamic contrast-enhanced magnetic resonance urography(dMRU)and scintigraphy 99m-technetium mercaptoacetyltriglycine(MAG-3)for the functional evaluation of *** Between 2016 and 2020,126 patients with UPJO underwent surgery at Robert Debré*** these,83 received a prenatal diagnosis,and 43 were diagnosed during *** of the 126 patients underwent surgery based on the clinical situation and postnatal ultrasound findings without undergoing functional imaging *** renal function was evaluated preoperatively using scintigraphy MAG-3(n=28),dMRU(n=53),or both(n=40).In this study,we included patients who underwent surgery for UPJO and scintigraphy MAG-3+dMRU but excluded those who underwent only scintigraphy MAG-3 or *** patients were divided into groups A(10%discrepancy).We examined the discrepancy in split renal function between the two modalities and investigated the possible risk *** The split renal function between the two kidneys was compared in 40 patients(28 boys and 12 girls)using scintigraphy MAG-3 and *** renal function,as determined using both modalities,showed a difference of10%in 9 *** of the relative renal function using dMRU revealed an excellent correlation coefficient with renal scintigraphy MAG-3 for both *** Our findings demonstrated that dMRU is equivalent to scintigraphy MAG-3 for evaluating split renal function in patients with UPJO.

关键词： Uteropelvic junction obstruction Scintigraphy 99m-technetium mercaptoacetyltriglycine Magnetic resonance imaging Dynamic contrast-enhanced magnetic resonance urography

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Tunneled tubularized bladder mucosal graft for long urethral reconstruction:is it a reliable option in selected complex cases in children and adolescents?

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Plastic and Aesthetic Research 2022年第1期9卷 585-595页

作者： Alaa.el-ghoneimi Amane-Allah Lachkar Pauline Lopez Anna.el Paye-Jaouen Matthieu Peycelon Department of Pediatric Surgery and Urology University Hospital Robert-DebréAPHPUniversitéParis CitéParis 75019France National Reference Center for Rare Urinary Tract Malformations(MARVU) Paris 75019France

Aim:We analyzed the use of tubularized tunneled bladder mucosa graft(TBMG)and its application as a salvage procedure or as primary surgery for long urethroplasty in children and *** attention was given to a new method to harvest a long bladder mucosa graft through a minimal ***:We analyzed the files of 10 patients who underwent TBMG urethroplasty at median age of 105 months(range 20-195 months).The indications were perineal hypospadias cripple in two,masculinizing genitoplasty for ovotesticular Ovotesticular Disorder of Sex Development(DSD)in two,perineal hypospadias in four,duplicated urethra in one,and complications of circumcision in *** reconstruction was performed in all *** first stage was removal of all fibrous tissues and efficient treatment of curvature and skin *** a minimal delay of one year,a free bladder mucosa graft was harvested through a minimal detrusotomy and *** of the graft was proceeded from the perineal urethrostomy to the ***:The graft was successfully harvested through the minimal detrusotomy approach for variable lengths of urethroplasty;the median length was 10.5 cm(range 8-16 cm).The median follow up was 61.7 months(range 18-160 months).TBMG was the last surgery with no redo in five cases(50%).Long stricture occurred in one case of primary perineal hypospadias and needed a redo staged *** patients performed self-dilatation for distal ***:The tunneled bladder mucosa tube graft technique represents a good alternative for a long urethroplasty in patients with a paucity of healthy *** minimal detrusotomy technique for graft retrieval may reduce graft harvesting morbidity.

关键词： Hypospadias bladder mucosa graft hypospadias cripples urethra reconstruction

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