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Robust interface and excellent as-built mechanical properties of Ti–6Al–4V fabricated through laser-aided additive manufacturing with powder and wire

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International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 154-168页

作者： Fei Weng Guijun bi Youxiang Chew Shang Sui Chaolin Tan Zhenglin Du Jinlong Su Fern Lan Ng Key Laboratory for Liquid-Solid Structural Evolution and Processing of Materials Ministry of EducationShandong Engineering&Technology Research Center for Superhard MaterialSchool of Materials Science and EngineeringShandong UniversityJinan 250061China Institute of Intelligent Manufacturing Guangdong Academy of SciencesGuangzhou 510095China Singapore Institute of Manufacturing Technology 5 Cleantech Loop636732Singapore

The feasibility of manufacturing Ti-6Al-4V samples through a combination of laser-aided additive manufacturing with powder(LAAM_(p))and wire(LAAM_(w))was explored.A process study was first conducted to successfully circumvent defects in Ti-6Al-4V deposits for LAAM_(p) and LAAM_(w),*** the optimized process parameters,robust interfaces were achieved between powder/wire deposits and the forged substrate,as well as between powder and wire *** characterization results revealed the epitaxial prior β grains in the deposited Ti-6Al-4V,wherein the powder deposit was dominated by a finerα′microstructure and the wire deposit was characterized by lamellar α *** mechanisms of microstructure formation and correlation with mechanical behavior were analyzed and *** mechanical properties of the interfacial samples can meet the requirements of the relevant Aerospace Material Specifications(AMS 6932)even without post heat *** fracture occurred within the interfacial area,further suggesting the robust *** findings of this study highlighted the feasibility of combining LAAM_(p) and LAAM_(w) in the direct manufacturing of Ti-6Al-4V parts in accordance with the required dimensional resolution and deposition rate,together with sound strength and ductility balance in the as-built condition.

关键词： laser-aided additive manufacturing powder deposition wire deposition interfacial characteristic mechanical behavior

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Cortico-striatal gamma oscillations are modulated by dopamine D3 receptors in dyskinetic rats

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Neural Regeneration Research 2025年第4期20卷 1164-1177页

作者： Pengfei Wang Yuewei bi Min Li Jiazhi Chen Zhuyong Wang Huantao Wen Ming Zhou Minjie Luo Wangming Zhang Neurosurgery Center Department of Pediatric NeurosurgeryGuangdong Provincial Key Laboratory on Brain Function Repair and RegenerationZhujiang HospitalSouthern Medical UniversityGuangzhouGuangdong ProvinceChina

Long-term levodopa administration can lead to the development of levodopa-induced *** oscillations are a widely recognized hallmark of abnormal neural electrical activity in levodopa-induced ***,studies have reported increased oscillation power in cases of levodopa-induced ***,little is known about how the other electrophysiological parameters of gamma oscillations are altered in levodopa-induced ***,the role of the dopamine D3 receptor,which is implicated in levodopa-induced dyskinesia,in movement disorder-related changes in neural oscillations is *** found that the cortico-striatal functional connectivity of beta oscillations was enhanced in a model of Parkinson’s ***,levodopa application enhanced cortical gamma oscillations in cortico-striatal projections and cortical gamma aperiodic components,as well as bidirectional primary motor cortex(M1)↔dorsolateral striatum gamma *** of PD128907(a selective dopamine D3 receptor agonist)induced dyskinesia and excessive gamma oscillations with a bidirectional M1↔dorsolateral striatum ***,administration of PG01037(a selective dopamine D3 receptor antagonist)attenuated dyskinesia,suppressed gamma oscillations and cortical gamma aperiodic components,and decreased gamma causality in the M1→dorsolateral striatum *** findings suggest that the dopamine D3 receptor plays a role in dyskinesia-related oscillatory activity,and that it has potential as a therapeutic target for levodopa-induced dyskinesia.

关键词： aperiodic components dopamine D3 receptor dorsolateral striatum functional connectivity gamma oscillations levodopa-induced-dyskinesia local field potentials neuromodulation Parkinson’s disease primary motor cortex

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Interaction between Janus Green B and bovine serum albumin:Electrochemistry and spectroscopy studies

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Chinese Chemical Letters 2011年第6期22卷 717-720页

作者： Neslihan zdemir Serkan zdemir Ender bier Ondokuz Mayrs University Faculty of Arts and Sciences Department of Chemistry

In this study,voltammetric and spectroscopic investigation of the interaction between Janus Green B（JGB） and bovine serum albumin（BSA） was *** interaction was observed at Britton-Robinson buffer（pH 7.0）.When JGB was added to solution containing BSA,the peak currents of BSA decrease with the increasing of JGB concentrations which is due to the interaction of JGB and *** binding constant of JGB with BSA was obtained by voltammetric ***,this interaction was supported by means of UV-vis spectroscopic *** UV-vis absorption spectra of JGB in the presence of BSA decrease with the increasing of BSA concentrations.

关键词： Voltammetry Bovine serum albumin Janus Green B Interaction

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Spark Plasma Sintering of Boron Carbide Using Ti_(3)SiC_(2) as a Sintering Additive

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Journal of Wuhan University of Technology(Materials Science) 2024年第3期39卷 645-650页

作者： Hülya biçer Mustafa Tuncer Hasan Göçmez Iurii Bogomol Valerii Kolesnichenko Andrey Ragulya Kutahya Dumlupinar University School of EngineeringDepartment of Metallurgical and Materials EngineeringKütahya 43100Tur-key Boron Based Advanced Ceramics Application and Research Center Kütahya Dumlupınar UniversityKütahya 43100Turkey Advanced Technologies Center(İLTEM) Kütahya Dumlupınar UniversityKütahya 43000Turkey Department of High-Temperature Ma-terials and Powder Metallurgy National Technical University of Ukraine“Igor Sikorsky Kyiv Polytechnic Institute”Kyiv 03056Ukraine Frantsevich Institute for Problems of Materials Science National Academy of Sciences of UkraineKyiv 03056Ukraine

Boron carbide has unique properties for wide application possibilities;however,poor sinterability limits its *** approach to overcome this limitation is the addition of secondary phases into boron *** carbide based composite ceramics are produced by the direct addition of secondary phases into the structure or via reactive sintering using a sintering *** present study investigated the effect of Ti_(3)SiC_(2) addition to boron carbide by reactive spark plasma sintering in the range of 1700-1900℃.Ti_(3)SiC_(2) phase decomposed at high temperatures and reacted with B4C to form secondary phases of TiB2 and *** results demonstrated that the increase of Ti_(3)SiC_(2) addition(up to 15 vol%)effectively promoted the densification of B4C and yielded higher ***,as the amount of Ti_(3)SiC_(2) increased further,the formation of microstructural inhomogeneity and agglomeration of secondary phases caused a decrease in hardness.

关键词： reactive sintering SPS boron carbide MAX phase

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Surgery for hepatocellular carcinoma with tumor thrombosis in inferior vena cava: A case report

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World Journal of Clinical Cases 2021年第36期9卷 11495-11503页

作者： Zun-Yi Zhang er-Lei Zhang bi-Xiang Zhang Wei Zhang Research Laboratory and Hepatic Surgery Center Department of Hepatic SurgeryTongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430000Hubei ProvinceChina

BACKGROUND Hepatocellular carcinoma(HCC)accompanied by a tumor thrombus is very ***,the treatment strategy is controversial and varies by the location of the *** SUMMARY We report herein a case of HCC with a tumor thrombus in the suprahepatic inferior vena cava(IVC),which was successfully treated by hepatectomy combined with thrombectomy following sorafenib chemotherapy.A 47-year-old woman with chronic hepatitis was diagnosed with *** tomography and magnetic resonance imaging showed that the tumor lesion was located in the right half of the liver,and a tumor thrombus was detected in the suprahepatic IVC near the right *** multi-departmental discussion and patient informed consent,right major hepatectomy and total removal of the tumor thrombus were successfully performed under cardiopulmonary *** were no serious complications after *** sorafenib treatment,no recurrence has been detected so far(11 mo later).CONCLUSION Surgical treatment followed by adjuvant sorafenib therapy might be an acceptable choice for HCC patients with tumor thrombosis in the IVC.

关键词： Hepatocellular carcinoma Tumor thrombosis Inferior vena cava Hepatectomy Thrombectomy Sorafenib Cardiopulmonary bypass Case report

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Optimization of regional nodal irradiation in the era of sentinel lymph node biopsy

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Cancer biology & Medicine 2023年第2期20卷 89-92页

作者： Zhao bi Xue’er Wang Pengfei Qiu Peng Chen Yongsheng Wang Shandong Cancer Hospital and Institute Shandong First Medical University and Shandong Academy of Medical SciencesJinan 250017China Tianjin Medical University Cancer Institute&Hospital National Clinical Research Center for CancerKey Laboratory of Cancer Prevention and TherapyTianjinTianjin's Clinical Research Center for CancerTianjin 300060China

Historically,axillary lymph node dissection(ALND)was the standard management for axillary sentinel lymph node(SLN)-positive patients,because it enables full assessment of overall axillary lymph node(ALN)metastasis sta... 详细信息

关键词： lymph metastasis dissection

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从家庭视角看中国女性劳动参与率的下降趋势

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武汉大学学报（哲学社会科学版） 2025年第1期78卷 133-145页

作者：赵耀辉毕汝岱武汉大学武汉大学董辅礽经济社会发展研究院湖北武汉430072 北京大学国家发展研究院北京100091

随着社会经济的发展和人口结构的深刻调整,中国女性劳动参与率发生了显著变化。改革开放初期,中国女性劳动参与率显著高于欧美主要发达国家的水平,但近年来大幅下降,已接近其平均值。研究发现,已生育女性劳动参与率的下降是整体趋势的... 详细信息

随着社会经济的发展和人口结构的深刻调整,中国女性劳动参与率发生了显著变化。改革开放初期,中国女性劳动参与率显著高于欧美主要发达国家的水平,但近年来大幅下降,已接近其平均值。研究发现,已生育女性劳动参与率的下降是整体趋势的主要驱动力,而婚育模式的转变在一定程度上对这一趋势起到了缓冲作用。对于已婚女性而言,学龄前子女的照料负担逐渐成为劳动市场参与的核心制约因素。女性教育水平的提升通过禀赋和系数效应显著促进了劳动参与,但配偶教育水平的影响由正向转为负向,说明家庭收入能力的提高减弱了女性劳动参与的经济动机,强化了性别分工的传统趋势。优化育儿支持体系、促进性别平等以及营造职场友好环境,是缓解婚育负担对女性劳动市场参与约束的关键政策方向。

关键词：女性劳动参与率婚育模式育儿成本

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Spontaneous calcaneal fracture in patients with diabetic foot ulcer: Four cases report and review of literature

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World Journal of Clinical Cases 2016年第7期4卷 181-186页

作者： Mehtap Evran Murat Sert Tamer Tetiker Gamze Akku? ?mer Sunkar bi?er Department of Internal Medicine Division of Endocrinology Cukurova University Medical Faculty University of Cukurova in Adana Department of Orthopedics and Trau-matology Cukurova University Medical Faculty University of Cukurova in Adana

Spontaneous calcaneal fractures in diabetic patients without obvious trauma may occur, sometimes accompanying diabetic foot ulcers. In the current study we report four cases who were hospitalized for diabetic foot ulcer with concomitant calcaneal fractures. There were four diabetic patients(one type 1 and three type 2) who registered with diabetic foot ulcers with coexisting calcaneal fractures, all of which were classified as Type A according to Essex Lopresti Calcaneal Fracture Classification. Two of the patients with renal failure were in a routine dialysis program, as well as vascular compromise and osteomyelitis in all of the patients. The diabetic foot ulcer of the 61 years old osteoporotic female patient healed with local debridement, vacuum assisted closure and then epidermal growth factor while the calcaneal fracture was then followed by elastic bandage. In two patients could not prevent progression of diabetic foot ulcers and calcaneal fractures to consequent below-knee amputation. The only patient with type 1 diabetes mellitus improved with antibiotic therapy and split thickness skin grafting, while the calcaneal fracture did not heal. In the current study we aimed to emphasize the spontaneous calcaneal fractures as possible co-existing pathologies in patients with diabetic foot ulcers. After all the medical treatment, amputation below knee had to be performed in 2 patients. It should be noted that other accompanying conditions such as impaired peripheral circulation, osteomyelitis, chronic renal failure, and maybe osteoporosis is a challenge of the recovery of calcaneal fractures and accelerate the progress to amputation in diabetic patients.

关键词： Diabetes mellitus Foot ulcer Calcaneal fracture

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一种基于柱面镜聚焦系统的高灵敏度全谱光谱仪

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光谱学与光谱分析 2025年第1期45卷 222-230页

作者：陈吉文陈作儿赵迎北方工业大学电气与控制工程学院北京100144

很多元素的最灵敏谱线主要分布在紫外波段。一些常被作为检测对象的重要元素,例如C、P和S,其谱线甚至位于200 nm以下的真空紫外波段。然而真空紫外波段内的辐射极易受空气吸收而无法在空气中传输。因此为了适用于紫外波段各谱线的检测,... 详细信息

很多元素的最灵敏谱线主要分布在紫外波段。一些常被作为检测对象的重要元素,例如C、P和S,其谱线甚至位于200 nm以下的真空紫外波段。然而真空紫外波段内的辐射极易受空气吸收而无法在空气中传输。因此为了适用于紫外波段各谱线的检测,常使用光程短、系统精简的罗兰圆光学系统作为光谱仪的色散系统,并且在进行检测分析时,还需对设备腔体内部建立相对真空的环境进行实验,进而减小实验环境对真空紫外波段内各谱线强度的削弱作用。然而即使在该条件下,P和S这两种元素在真空紫外波段的谱线灵敏度仍然较弱。为此为了实现真空紫外波段范围内的高灵敏度,本研究在距离像面前30 mm处位置设计了一个柱面镜聚焦系统。其采用了材料为CaF_(2)、中心厚度为5 mm以及弧矢面曲率半径为22.06 mm的柱面镜作为核心部件。并利用仿真软件Zemax对设计的光学系统进行仿真与优化,以及从非序列模式下的辐射照度仿真结果可知,柱面镜聚焦系统在几乎不影响分辨率的情况下对各波长成像灵敏度有较大的提升。最后以中低合金钢为检测样品,使用电火花激发光源对样品中各元素在紫外波段内的各谱线进行激发,进而验证光谱仪的各项性能:通过一次拟合、参比拟合以及二次拟合,建立每个元素谱峰强度和实际含量之间的数学模型,并算得各元素的拟合优度R^(2)均在0.99以上;柱面镜聚焦系统显著提高了设备在真空紫外波段的灵敏度,响应提高了1倍以上。实验结果表明,柱面镜聚焦系统的设计方法对于提升罗兰圆色散系统的灵敏度具有一定的参考价值。

关键词：紫外光谱罗兰圆光学系统柱面镜灵敏度拟合优度

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Treatment for hepatocellular carcinoma with tumor thrombosis in the hepatic vein or inferior vena cava:A comprehensive review

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World Journal of Gastrointestinal Surgery 2021年第8期13卷 796-805页

作者： Zun-Yi Zhang er-Lei Zhang bi-Xiang Zhang Xiao-Ping Chen Wei Zhang Research Laboratory and Hepatic Surgery Center Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 434000Hubei ProvinceChina

Hepatocellular carcinoma(HCC)is the most common type of liver cancer with a high mortality rate *** percentage of HCC patients with vascular invasion is ***,tumor thrombus in the hepatic vein(HVTT)has a lower incidence than tumor thrombus in the portal vein(PVTT).Conventionally,HCC patients with HVTT are treated the same as HCC patients with PVTT and offered sorafenib or other systemic ***,according to recent studies,it is evident that HCC with HVTT shows different outcomes when classified into different *** this review,we discuss the recent progress and changes in treatment of HCC with HVTT.

关键词： Hepatocellular carcinoma Vascular invasion Surgery Transarterial chemoembolization

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