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Ground-based and additional science support for SMILE

Earth and Planetary Physics 2024年第1期8卷 275-298页

作者： J.A.Carter M.Dunlop C.Forsyth K.Oksavik E.Donovon A.Kavanagh S.E.Milan T.Sergienko R.C.Fear D.G.Sibeck M.Connors T.Yeoman X.Tan M.G.G.T.Taylor K.McWilliams J.Gjerloev R.Barnes D.D.Billet G.Chisham a.dimmock M.P.Freeman D.-S.Han M.D.Hartinger S.-Y.W.Hsieh Z.-J.Hu M.K.James L.Juusola K.Kauristie E.A.Kronberg M.Lester J.Manuel J.Matzka I.McCrea Y.Miyoshi J.Rae L.Ren F.Sigernes E.Spanswick K.Sterne A.Steuwer T.Sun M.-T.Walach B.Walsh C.Wang J.Weygand J.Wild J.Yan J.Zhang Q.-H.Zhang Planetary Sciences Group School of Physics and AstronomyUniversity of LeicesterUniversity RoadLeicesterLE17RHUK Rutherford Appleton Laboratory Space Science Technology Facilities CouncilOxfordshireUK School of Space and Environment Beihang UniversityBeijing 100191China Key Laboratory of Space Environment Monitoring and Information Processing Ministry of Industry and Information TechnologyBeijing 100017China Department of Space and Climate Physics UCLMullard Space Science LaboratoryHolmbury St.MaryDorkingSurreyRH56NTUK Birkeland Centre for Space Science Department of Physics and Technology.University of BergenBergenNorway Department of Physics and Astronomy University of Calgary2500 University DriveCalgaryAlbertaCanada T2N 1N4 British Antarctic Survey CambridgeUK Swedish Institute of Space Physics KirunaSweden West Highfield Campus University of SouthamptonUniversity RoadSO171BJUK Goddard Space Flight Center NASAGreenbeltMarylandUSA Athabasca University AthabascaCanada ESTEC European Space AgencyNetherlands University of Saskatchewan SaskatoonCanada The Johns Hopkins University Applied Physics Laboratory LaurelMarylandUSA Swedish Institude of Space Physics UppsalaSE 75121Sweden Tongji University Shanghai 200092China Center for Space Plasma Physics Space Science Institute4765 Walnut Street Suite BBoulderColorado80301USA Polar Research Institute of China Shanghai 200136China Finnish Meteorological Institute(FMI) Finland Department of Earth and Environmental Sciences(Geophysics) Ludwig Maximilian University of Munich(LMU)MunichTheresienstr.41MunichD-80333Germany Canadian Space Agency MontrealCanada GFZ German Research Centre for Geosciences PotsdamGermany Nagoya University Institute for Space Earth Environment ResearchCenter for Integrated Data ScienceNagoyaAichiJP 464-8601 Northumbria University Newcastle upon TyneTyne and WearUK NE18ST National Space Science Center Chinese Academy SciencesBeijing 100190China Arctic Geophysics University Centre in Svalbard

The joint European Space Agency and Chinese Academy of Sciences Solar wind Magnetosphere Ionosphere Link Explorer(SMILE)mission will explore global dynamics of the magnetosphere under varying solar wind and interplanetary magnetic field conditions,and simultaneously monitor the auroral response of the Northern Hemisphere *** these large-scale responses with medium and fine-scale measurements at a variety of cadences by additional ground-based and space-based instruments will enable a much greater scientific impact beyond the original goals of the SMILE ***,we describe current community efforts to prepare for SMILE,and the benefits and context various experiments that have explicitly expressed support for SMILE can offer.A dedicated group of international scientists representing many different experiment types and geographical locations,the Ground-based and Additional Science Working Group,is facilitating these *** include constructing an online SMILE Data Fusion Facility,the discussion of particular or special modes for experiments such as coherent and incoherent scatter radar,and the consideration of particular observing strategies and spacecraft *** anticipate growing interest and community engagement with the SMILE mission,and we welcome novel ideas and insights from the solar-terrestrial community.

关键词： magnetosphere ionosphere magnetosphere-ionosphere coupling ground-based experimentation SMILE conjunctions missions

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Mshpy23:a user-friendly,parameterized model of magnetosheath conditions

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Earth and Planetary Physics 2024年第1期8卷 89-104页

作者： Jaewoong Jung Hyunju Connor Andrew dimmock Steve Sembay Andrew Read Jan Soucek NASA Goddard Space Flight Center GreenbeltMDUSA Department of Astronomy University of MarylandCollege ParkMDUSA Swedish Institude of Space Physics UppsalaSweden University of Leicester LeicesterUK Institute of Atmospheric Physics Academy of Sciences of the Czech Republic

Lunar Environment heliospheric X-ray Imager(LEXI)and Solar wind−Magnetosphere−Ionosphere Link Explorer(SMILE)will observe magnetosheath and its boundary motion in soft X-rays for understanding magnetopause reconnection modes under various solar wind conditions after their respective launches in 2024 and *** conditions,namely,plasma density,velocity,and temperature,are key parameters for predicting and analyzing soft X-ray images from the LEXI and SMILE *** developed a userfriendly model of magnetosheath that parameterizes number density,velocity,temperature,and magnetic field by utilizing the global Magnetohydrodynamics(MHD)model as well as the pre-existing gas-dynamic and analytic *** this parameterized magnetosheath model,scientists can easily reconstruct expected soft X-ray images and utilize them for analysis of observed images of LEXI and SMILE without simulating the complicated global magnetosphere ***,we created an MHD-based magnetosheath model by running a total of 14 OpenGGCM global MHD simulations under 7 solar wind densities(1,5,10,15,20,25,and 30 cm)and 2 interplanetary magnetic field Bz components(±4 nT),and then parameterizing the results in new magnetosheath *** compared the magnetosheath model result with THEMIS statistical data and it showed good agreement with a weighted Pearson correlation coefficient greater than 0.77,especially for plasma density and plasma ***,we compiled a suite of magnetosheath models incorporating previous magnetosheath models(gas-dynamic,analytic),and did two case studies to test the *** MHD-based model was comparable to or better than the previous models while providing self-consistency among the magnetosheath ***,we constructed a tool to calculate a soft X-ray image from any given vantage point,which can support the planning and data analysis of the aforementioned LEXI and SMILE missions.A release of the code has been uploaded to a Git

关键词： magnetosheath python modeling

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The relationship between self-presentation concerns and pre-game affect among adolescent American football players

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Journal of Sport and Health Science 2013年第3期2卷 168-175页

作者： Leslie Podlog Marc Lochbaum Jens Kleinert James dimmock Maria Newton Stefanie Schulte Department of Exercise and Sport Science University of Utah Department of Health Exercise and Sport SciencesTexas Tech University Department of Health&Social Psychology Institute of PsychologyGerman Sport University Cologne School of Sport Science Exercise and HealthThe University of Western Australia Institute of Movement and Neurosciences German Sport University Cologne

Background： The influence of self-presentation concerns on the adolescent sport experience has received scant empirical attention. The purpose of this investigation was to prospectively examine the relationship among self-presentational concerns and pre-game affective states among middle and high school aged football players. Methods： American football players （n = 112; mean age = 15.57 years） completed a measure of self-presentational concerns （SPSQ, McGowan, et al., 2008） a week prior to the measurement of selected pre-game affective states （i.e., attentiveness, self-assurance, serenity, and fear）. Results： Regression analyses revealed that concerns about appearing athletically untalented negatively contributed to the significant prediction （p 〈 0.001） of pre-game attentiveness, /3 = -0.43, Radj ^2 19.5% （p 〈 0.001）, and self-assurance, /3 = -0.38, R^dj = 11.9% （p 〈 0.01）. Conclusion： These findings highlight the importance of reducing self-presentational concerns in promoting positive pre-game mental states that likely impact the quality of athletes＇ competitive play and experience. Copyright @ 2012, Shanghai University of Sport. Production and hosting by Elsevier B.V. All rights reserved.

关键词： Attentiveness Longitudinal Self-assurance Self-presentation

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动物病毒中和作用的机理

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国外医学(微生物学分册) 1985年第4期 155-158页

作者： dimmock NJ

本综述阐述中和抗体同病毒结合导致病毒失去感染性的机理。目前,人们对中和抗体与病毒抗原决定簇之间的相互作用及病毒如何失去感染性的问题了解甚少。过去有关中和作用的理论是建立在逻辑性错误基础上的,认为(1)中和作用服从单一攻击... 详细信息

本综述阐述中和抗体同病毒结合导致病毒失去感染性的机理。目前,人们对中和抗体与病毒抗原决定簇之间的相互作用及病毒如何失去感染性的问题了解甚少。过去有关中和作用的理论是建立在逻辑性错误基础上的,认为(1)中和作用服从单一攻击动力学(Single-hit Kinetics),即一个抗体分子能灭活一个感染性病毒颗粒;(2)中和抗体

关键词：中和作用单克隆病毒颗粒交联感染性抗体分子脊髓灰质炎病毒小儿麻痹病毒肠道病毒流感病毒病毒蛋白

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为未来学校打造创新的学习环境——基于高效领导力的10项有力主张

未来教育研究

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未来教育研究 2023年第1期 6-10页

作者： Clive dimmock 英国格拉斯哥大学

经济全球化背景下，创新成为经济发展的主要动力。学校的发展也要从建设创新的学习环境开始，因为学习环境是学生最直接的学习场所，也是教育发生的真实情境。未来学校需要以学习环境的创新来提升教育教学质量，其中高效的领导力在学习...

经济全球化背景下，创新成为经济发展的主要动力。学校的发展也要从建设创新的学习环境开始，因为学习环境是学生最直接的学习场所，也是教育发生的真实情境。未来学校需要以学习环境的创新来提升教育教学质量，其中高效的领导力在学习环境创新过程中属于一个关键的因素，它能平稳地、有方向地、高效地引领创新学习环境的建构与发展。

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局部应用吡美莫司和他克莫司治疗异位性皮炎的疗效和耐受性:随机对照实验的Meta分析

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世界核心医学期刊文摘（皮肤病学分册） 2005年第7期1卷 1-2页

作者： Ashcroft D.M. dimmock P. Garside R. 刘燕 Sch. of Pharm./Pharmaceutical Sci. University of Manchester Manchester M13 9PLUnited Kingdom

Objective: To determine the efficacy and tolerability of topical pimecrolimus and tacrolimus compared with other treatments for atopic dermatitis. Design: Systematic review and meta- analysis. Data sources: Electronic searches of Cochrane Library, Medline, and Embase. Study selection: Randomised controlled trials of topical pimecrolimus or tacrolimus reporting efficacy outcomes or tolerability. Data extraction: Efficacy: investigators’ global assessment of response; patients’ global assessment of response; proportions of patients with flares of atopic dermatitis; and improvements in quality of life. Tolerability: overall rates of withdrawal, withdrawal due to adverse events, and the proportions of patients with burning of the skin and skin infections. Data synthesis: 4186 of 6897 participants in 25 randomised controlled trials received pimecrolimus or tacrolimus. Both drugs were significantly more effective than a vehicle control. Tacrolimus 0.1% was as effective as potent topical corticosteroids at three weeks and more effective than combined treatment with hydrocortisone butyrate 0.1% (potent used on trunk) plus hydrocortisone acetate 1% (weak used on face) at 12 weeks (number needed to treat (NNT)=6). Tacrolimus 0.1% was also more effective than hydrocortisone acetate 1% (NNT=4). In comparison, tacrolimus 0.03% was more effective than hydrocortisone acetate 1% (NNT=5) but less effective than hydrocortisone butyrate 0.1% (NNT=- 8). Direct comparisons of tacrolimus 0.03% and tacrolimus 0.1% consistently favoured the higher strength formulation, but efficacy differed significantly between the two strengths only after 12 weeks’ treatment (rate ratio 0.80, 95% confidence interval 0.65 to 0.99). Pimecrolimus was far less effective than betamethasone valerate 0.1% (NNT=- 3 at three weeks). Pimecrolimus and tacrolimus caused significantly more skin burning than topical corticosteroids. Rates of skin infections in any of the comparisons did not differ. Conclusions: Both t

关键词：异位性皮炎 Meta分析吡美莫司随机对照实验局部应用外用激素戊酸倍他米松电子检索丁酸酯总比例

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局部应用吡美莫司和他克莫司治疗特异性皮炎的疗效和耐受性:随机对照试验的汇总分析

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英国医学杂志中文版 2005年第3期8卷 193-193页

作者： Darren M Ashcroft Paul dimmock Ruth Garside Ken Stein Hywel C Williams 王世贤

目的：比较吡美莫司(Pimecrolimus)和他克莫司(tacrolimus)局部用药与其他方法治疗特异性皮炎的疗效和耐受性。设计：系统回顾和汇总分析。数据来源：Cochrane图书馆，Medline和Embase数据库。纳入标准：能够说明吡美莫司和他克莫司局... 详细信息

目的：比较吡美莫司(Pimecrolimus)和他克莫司(tacrolimus)局部用药与其他方法治疗特异性皮炎的疗效和耐受性。设计：系统回顾和汇总分析。数据来源：Cochrane图书馆，Medline和Embase数据库。纳入标准：能够说明吡美莫司和他克莫司局部用药治疗特异性皮炎的疗效和耐受性的随机对照试验。数据提取：疗效：本试验中对调查对象及特异性皮炎患者总的评估，特异性皮炎病情加剧者比例及生活质量改善情况。耐受性：总停药率，由毒副作用应起的停药，皮肤烧灼感及感染的患者比率。数据汇总：25项随机对照试验中共有6897例受试对象，其中4186例接受了2种药物的治疗，其疗效比赋形剂对照组显著。0.1%他克莫司和有效的局部用皮质激素在用药3周后疗效基本相似，但比0.1%氢化可的松丁酸酯(有效躯干用药)和0.1%的氢化可的松醋酸酯(较少用于面部)联合用药12周后疗效较好(需要治疗的患者数NNT＝6)，且比单用0.1%氢化可的松醋酸酯疗效好(NNT＝4)。0.03%他克莫司比1%氢化可的松醋酸酯疗效好(NNT＝5)，但比氢化可的松丁酸酯疗效差(NNT=-8)。0.1%和0.03%的他克莫司治疗特异性皮炎疗效较好，但在用药12周后两者之间疗效差异较显著(率比为0.8，95%可信区间为0.65～0.95)。吡美莫司用药3周后其疗效明显差于戊酸倍他米松(NNT＝-3)。吡美莫司和他克莫司比局部用皮质激素更易出现皮肤烧灼感，但各组皮肤感染率比较无统计学意义。结论：局部应用他克莫司和吡美莫司治疗特异性皮炎，其疗效均优于安慰剂对照组，但由于本试验中未涉及长期用药的安全性，故与局部应用皮质激素相比尚不清楚是否具有优越性。局部应用他克莫司的疗效与皮质激素相似，但后者更易引起毒副作用，因此他克莫司可以长期用药治疗耐受的特异性皮炎患者。尚缺乏与作用温和的皮质激素相比较的重要数据，故对局部皮质激素无效的患者，目前还不清楚其疗效。

关键词：特异性皮炎他克莫司吡美莫司随机对照试验耐受性汇总分析局部应用疗效治疗局部用药

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