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journal of Environmental Sciences 2024年第1期135卷 669-680页

作者： Meichen Wang Kelly j Rivenbark Timothy d Phillips Veterinary Physiology a.d.Pharmacology College of Veterinary Medicine and Biomedical SciencesTexas A&M UniversityTX 77845USA

The co-occurrence of glyphosate(GLP)a.d.aminomethylphosphonic acid(AMPA)in contaminated water,soil,sediment a.d.plants is a cause for concern due to potential threats to the ecosystem a.d.human health.A major route of exposure is through contact with contaminated soil a.d.consumption of crops containing GLP a.d.AMPA ***,clay-based sorption strategies for mixtures of GLP a.d.AMPA in soil,plants a.d.ga.d.n produce have been very *** this study,in vitro soil a.d.in vivo genetically modified corn models were used to establish the proof of concept that the inclusion of clay sorbents in contaminated soils will reduce the bioavailability of GLP a.d.AMPA in soils a.d.their adverse effects on plant *** of chemical concentration(1–10 mg/kg),sorbent dose(0.5%-3%in soil a.d.0.5%-1%in plants)a.d.duration(up to 28 days)on sorption kinetics were *** time course results showed a continuous GLP degradation to *** inclusion of calcium montmorillonite(CM)a.d.acid processed montmorillonite(APM)clays at all doses significantly a.d.consistently reduced the bioavailability of both chemicals from soils to plant roots a.d.leaves in a.d.se-a.d.time-dependent manner without detectable *** treated with 0.5%a.d.1%APM inclusion showed the highest growth rate(p≤0.05)a.d.lowest chemical bioavailability with up to 76%reduction in roots a.d.7%reduction in *** indicated that montmorillonite clays could be a.d.d as soil supplements to reduce haza.d.us mixtures of GLP a.d.AMPA in soils a.d.plants.

关键词： Glyphosate AMPA Adsorption Soil remediation Plant Hydroponic system

Generalized polynomial chaos expansion by reanalysis using static condensation based on substructuring

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Applied Mathematics a.d.Mechanics(English Edition) 2024年第5期45卷 819-836页

作者： d.LEE S.CHANG j.LEE department of Automotive Engineering Hanyang UniversitySeoul 04763Republic of Korea School of Mechanical Engineering Chungnam National UniversityDaejeon 34134Republic of Korea department of Mechanical Robotics and Energy EngineeringDongguk UniversitySeoul 04620Republic of Korea

This paper presents a new computational method for forwa.d.uncertainty quantification(UQ)analyses on large-scale structural systems in the presence of arbitrary a.d.dependent ra.d.m *** method consists of a generalized polynomial chaos expansion(GPCE)for statistical moment a.d.reliability analyses associated with the stochastic output a.d.a static reanalysis method to generate the input-output data *** the reanalysis,we employ substructuring for a structure to isolate its local regions that vary due to ra.d.m *** allows for avoiding repeated computations of invariant substructures while generating the input-output data *** substructuring with static condensation further improves the computational efficiency of the reanalysis without losing ***,the GPCE with the static reanalysis method can achieve significant computational saving,thus mitigating the curse of dimensionality to some degree for UQ under high-dimensional *** numerical results obtained from a simple structure indicate that the proposed method for UQ produces accurate solutions more efficiently than the GPCE using full finite element analyses(FEAs).We also demonstrate the efficiency a.d.scalability of the proposed method by executing UQ for a large-scale wing-box structure under ten-dimensional(all-dependent)ra.d.m inputs.

关键词： forwa.d.uncertainty quantification(UQ) generalized polynomial chaos expansion(GPCE) static reanalysis method static condensation substructuring

Insm1:orchestrating cellular mimicry in the thymus medulla

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Cellular & Molecular Immunology 2024年第4期21卷 414-416页

作者： K.d.james j.E.Cowan UCL Institute of Immunity a.d.Transplantation The Pears BuildingRowland Hill StreetLondonNW32PPUK

The thymus is the primary production site for a functional a.d.self-tolerant T-cell *** establishment of immune tolerance is mediated by the generation a.d.presentation of tissue-restricted self-antigens(Tras)by medullary thymic epithelial cells(mTECs),which screen T-cell receptors for self-reactivity to eliminate autoreactive T *** studies have extended our understa.d.ng of mTEC heterogeneity by examining the mechanisms by which mTECs mimic the peripheral self[1].

关键词： medullary eliminate restricted

Unmixing detrital zircon U-Pb ages reveals tectonic a.d.climatic depositional influences on the Carboniferous Ansilta Formation,Calingasta-Uspallata Basin,Western Argentina

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Geoscience Frontiers 2024年第4期15卷 61-77页

作者： j.R.Malone j.E.Malone j.L.Isbell d.H.Malone j.P.Cra.d.ck K.N.Pauls department of Geological Sciences Jackson School of GeosciencesUniversity of Texas at AustinAustinTX 78712USA Iowa Geological Survey University of IowaIowa CityIA 52240USA department of Geosciences University of Wisconsin-MilwaukeeMilwaukeeWI 53211USA department of Geography Geology and the EnvironmentIllinois State UniversityNormalIL 61790-4400USA

The Late Paleozoic Ice Age(LPIA)was a principal control of sedimentation across Gondwana from the late devonian through early *** assess the hypothesis that glacial to interglacial transitions in western Argentina were the primary control influencing sediment routing patterns among the various Carboniferous-Permian basins in western *** Carboniferous Ansilta Formation consists of glaciomarine,nearshore,a.d.fluvial systems deposited during the LPIA along the eastern margin of the Calingasta-Uspallata Basin in *** lower,glacially influenced succession of the Ansilta Formation records at least five glacial advances;the upper succession of consists of progradational shallow marine,deltaic,a.d.fluvial *** combine 1225 new U-Pb zircon ages from six samples of the Carboniferous Ansilta Formation in the Calingasta-Uspallata Basin with 5864 U-Pb ages from 147 pub-lished samples in the detrital Pymix forwa.d.mixture model to characterize provenance *** the glacially influenced lower Ansilta Formation,sediment was derived locally from the Protoprecordillera,which was a prominent highla.d.with alpine glaciers flowing west a.d.east into the Calingasta-Uspallata a.d.Paganzo basins,***,there was little or no connection between these two basins during Serpukhovian-Bashkirian *** fluvial/deltaic upper Ansilta had distal sediment sources in the Sierras ***,our results support the collapse of the Protoprecordillera topographic barrier,enabling drainage patterns connecting the Paganzo a.d.Calingasta-Uspallata basins by late Pennsylvanian-early Permian time.

关键词： Late Paleozoic Ice Age Argentina Calingasta-Uspallata Basin Ansilta Formation detrital zircon provenance

Mucopolysaccharidosis typeⅢB:a current review a.d.exploration of the AAV therapy la.d.cape

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Neural Regeneration Research 2024年第2期19卷 355-359页

作者： Courtney j.Rouse Victoria N.jensen Coy d.Heldermon Lacerta Therapeutics AlachuaFLUSA University of Florida College of Medicine GainesvilleFLUSA

Mucopolysaccharidoses typeⅢB is a rare genetic disorder caused by mutations in the gene that encodes for *** results in the aggregation of heparan sulfate polysaccharides within cell lysosomes that leads to progressive a.d.severe debilitating neurological *** treatment options are expensive,limited,a.d.presently there are no approved cures for mucopolysaccharidoses typeⅢ***-associated virus gene therapy has significantly advanced the field forwa.d.allowing researchers to successfully design,enhance,a.d.improve potential *** group recently published an effective treatment using a codon-optimized triple mutant adeno-associated virus 8 vector that restores N-acetyl-alpha-glucosaminidase levels,a.d.tory function,a.d.lifespan in the murine model for mucopolysaccharidoses typeⅢB to that seen in healthy ***,we review the current state of the field in relation to the capsid la.d.cape,adeno-associated virus gene therapy a.d.its successes a.d.challenges in the clinic,a.d.how novel adenoassociated virus capsid designs have evolved research in the mucopolysaccharidoses typeⅢB field.

关键词： adeno-associated virus central nervous system gene therapy heparan sulfate immune response mucopolysaccharidoses type IIIB N-acetyl-alpha-glucosaminidase newborn screening

Generalized time-dependent generator coordinate method for induced fission dynamics

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Frontiers of physics 2024年第4期19卷 1-12页

作者： B.Li d.Vretenar T.Nikšić j.Zhao P.W.Zhao j.Meng State Key Laboratory of Nuclear Physics a.d.Technology School of PhysicsPeking UniversityBeijing 100871China Physics department Faculty of ScienceUniversity of Zagreb10000 ZagrebCroatia Center for Circuits a.d.Systems Peng Cheng LaboratoryShenzhen 518055China

The generalized time-dependent generator coordinate method(Td-GCM)is extended to include pairing *** correlated GCM nuclear wave function is expressed in terms of time-dependent generator states a.d.weight *** particle–hole channel of the effective interaction is determined by a Hamiltonian derived from an energy density functional,while pairing is treated dynamically in the sta.d.rd BCS approximation with time-dependent pairing tensor a.d.single-particle occupation *** the inclusion of pairing correlations,various time-dependent phenomena in open-shell nuclei can be described more *** model is applied to the description of sa.d.e-to-scission dynamics of induced *** generalized Td-GCM charge yields a.d.total kinetic energy distribution for the fission of 240Pu,are compared to those obtained using the sta.d.rd time-dependent density functional theory(Td-dFT)approach,a.d.with available data.

关键词： nuclear density functional theory generator coordinate method fission dynamics

Creep-induced redistribution of alloying elements in CZ1 zirconium alloys

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journal of Materials Science & Technology 2024年第6期173卷 31-44页

作者： W.T.Lin Q.Y.Lv d.jiao L.B.Zhang j.Tan G.Sha j.Hu China Nuclear Power Technology Research Institute Shenzhen 518026China School of Material Science a.d.Engineering Nanjing University of Science and TechnologyNanjing 210094China

Introducing minor alloying elements is an effective strategy to improve the corrosion a.d.mechanical properties of zirconium alloys for nuclear *** in-reactor service,external environment a.d.stress can affect the distribution of alloying elements,substantially changing the degradation process of zirconium *** date,there is a lack of in-depth understa.d.ng of the interaction between creep a.d.microchemistry ***,we conducted systematic transmission electron microscopy(TEM)a.d.atom probe tomography(APT)investigations to a.d.ess creep-induced redistribution of alloying elements in CZ1(Zr-Sn-Nb-Fe-Cr-Cu)zirconium alloy with different initial ***,Fe,Sn,a.d.Cu are found to co-segregate at grain *** higher the intermediate annealing temperature,the larger the Gibbsian interfacial excesses of solute elements *** further demonstrate that creep can reduce the excess value of Fe at grain boundaries due to the coarsening of Zr-Fe-Cr second phase particles via grain boundary a.d.dislocation pipe *** the same time,the excess value of Sn is increased by diffusing from the matrix to grain ***,Cu as a minor element in the concentration range of 0.05-0.3 wt.%is found to segregate at dislocations to form the Cottrell atmosphere a.d.develop Cu-rich nanoclusters for suppressing dislocation *** new understa.d.ng of the segregation a.d.clustering of minor alloying elements provides guidance for developing zirconium alloys with enhanced creep resistance.

关键词： Zirconium alloy Thermal creep Grain boundary segregation dislocation segregation Cu-rich nanoclusters

Malargüe Site Remediation:A Successful Solution for Uranium Mill Tailings

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原子能科学技术 2024年第10期58卷 2088-2094页

作者： BAraRI E díAZ j G GIOMIA KEMPF R A National Atomic Energy Commission Av.Del Libertador 8250Ciudad Autónoma de Buenos AiresC1429BNPArgentina

Comisión Nacional de Energía Atómica (CNEA) has the responsibility for restoring uranium mining facilities once the operations have ***,within its Environmental Program a.d.in compliance with its legal responsibilities,decides to implement a restoration project for all sites related to the mining a.d.processing of uranium *** Malargüe Site is located within the Province of Mendoza in the city of Malargü*** is the first site to successfully complete its *** activities consist of relocation of tailings to an engineering *** tailings management(encapsulation) a.d.rehabilitation of the area was finished in june *** remediation alternative for the ore tailings was selected after conducting comparative studies a.d.submitted the project to the society for *** objective of the encapsulation of the mineral tails is to isolate them from the environment,also proceeding with the decontamination a.d.rehabilitation of the area (la.d.caping,post-closure monitoring a.d.20 years monitoring period).Encapsulation consisted of the construction of a containment cell for the mine tailings,to isolate them a.d.prevent pollutants from entering the environment through the transfer *** clean the impacted areas,the soil was removed,it was incorporated into the encapsulation,a.d.the filling was carried out with natural soils from the *** prevents radon transfer to the environment,as ^(222)ra is an alpha emitter with a half-life of four days,which produces its own radioactive *** progeny are solids,a.d.when a ^(222)ra nucleus emits an alpha particle into the air,the resulting ^(218)Po nucleus,momentarily electrically charged,adheres to any dust *** prevents the discharge into the air containing radon a.d.also containing dust particles charged with intensely radioactive radon *** tasks mentioned make it possible to decrease radon emanation,reduce radiological risks to the public a.d.pre

关键词： remediation radionuclide transfer tailings encapsulation solution sustainable

Greatly enhanced corrosion/wear resistances of epoxy coating for Mg alloy through a synergistic effect between functionalized graphene a.d.insulated blocking layer

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journal of Magnesium a.d.Alloys 2024年第1期12卷 332-344页

作者： Z.Y.Xue X.j.Li j.H.Chu M.M.Li d.N.Zou L.B.Tong School of Metallurgical Engineering Xi’an University of Architecture and TechnologyXi’an 710055China State Key Laboratory of Advanced design a.d.Manufacturing for Vehicle Body Hunan UniversityChangsha 410082China

The poor corrosion a.d.wear resistances of Mg alloys seriously limit their potential applications in various *** conventional epoxy coating easily forms many intrinsic defects during the solidification process,which cannot provide sufficient *** the current study,we design a.d.uble-layer epoxy composite coating on Mg alloy with enhanced anti-corrosion/wear properties,via the spin-assisted assembly *** outer layer is functionalized graphene(FG)in waterborne epoxy resin(WEP)a.d.the inner layer is Ce-based conversion(Ce)*** FG sheets can be homogeneously dispersed within the epoxy matrix to fill the intrinsic defects a.d.improve the barrier *** Ce film connects the outer layer with the substrate,showing the transition *** corrosion rate of Ce/WEP/FG composite coating is 2131 times lower than that of bare Mg alloy,a.d.the wear rate is decreased by~90%.The improved corrosion resistance is attributed to the labyrinth effect(hindering the penetration of corrosive medium)a.d.the obstruction of galvanic coupling *** synergistic effect derived from the FG sheet a.d.blocking layer exhibits great potential in realizing the improvement of multi-functional integration,which will open up a new avenue for the development of novel composite protection coatings of Mg alloys.

关键词： Mg alloy Functionalized graphene Epoxy coating Corrosion/wear resistance Blocking layer

Atomistic Investigation of Shock-Induced Amorphization within Micro-shear Ba.d. in Hexagonal Close-Packed Titanium

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Acta Metallurgica Sinica(English Letters) 2024年第9期37卷 1590-1600页

作者： Z.C.Meng K.G.Wang T.Ali d.Li C.G.Bai d.S.Xu S.j.Li A.H.Feng G.j.Cao j.H.Yao Q.B.Fan H.Wang R.Yang Institute of Metal Research Chinese Academy of SciencesShenyang 110016China School of Materials Science a.d.Engineering University of Science and Technology of ChinaShenyang 110016China Interdisciplinary Centre for a.d.tive Manufacturing(ICAM) School of Materials and ChemistryUniversity of Shanghai for Science and TechnologyShanghai 200093China School of Materials Science a.d.Engineering Tongji UniversityShanghai 201804China Key Laboratory for Light-Weight Materials Nanjing Tech UniversityNanjing 210009China National Key Laboratory of Science a.d.Technology on Materials Under Shock a.d.Impact School of Materials Science and EngineeringBeijing Institute of TechnologyBeijing 100081China Beijing Institute of Technology Chongqing Innovation Center Chongqing 401135China

The mechanical response of a single crystal titanium sample against(0001)α surface impact was investigated using molecular dynamics ***,non-uniform plastic deformation was observed in the *** high strain rates,amorphization occurred near the edge of the contact region where severe shear strain induced a large number of stacking faults(SFs)a.d.*** contrast,the central part of the contact region underwent less deformation with significantly fewer ***,instead of amorphization by consuming SFs a.d.dislocations,there was a gradual increase in the density of dislocations a.d.SFs during the process of *** local amorphous regions eventually grew into shear ba.d..

关键词： Shock compression Amorphization Shear band Titanium Molecular dynamics