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华北地质 1981年第4期 1-16页

作者： j. Tarney B. Weaver s. A. Drury 高凡

英云闪长质—奥长花岗质成分的高Na/K比的片麻岩在苏格兰和东格陵兰太古代高级变质区中占优势。片麻岩的成分从超镁铁质变化到奥长花岗岩,但成分的分布是双模式的,特别是在角闪岩相的片麻岩带中尤是如此。英云闪长质片麻岩的Al2O3偏高... 详细信息

英云闪长质—奥长花岗质成分的高Na/K比的片麻岩在苏格兰和东格陵兰太古代高级变质区中占优势。片麻岩的成分从超镁铁质变化到奥长花岗岩,但成分的分布是双模式的,特别是在角闪岩相的片麻岩带中尤是如此。英云闪长质片麻岩的Al2O3偏高（平均大于15%）,CaO也高,但siO2多数低于70％,而以小型奥长花岗岩体和脉体为例外。ba和sr的含量高,而sr甚至在硅质片麻岩中仍居高位。在Y与siO2间和TiO2与siO2之间显然存在着负相关。CeN/YN比值随siO2而增加,主要是较富硅质片麻岩中重稀土元素大大减低的结果,其比值可以超过100。然而有些奥长花岗质岩石中,稀土总量和Ce/Yb比值是较低的。虽然Eu异常之量与总稀土的含量有关,但许多硅质片麻岩具有显著正Eu异常,而有一些奥长花岗质岩石具不明显的负Eu异常。地球化学有力地表明,假如片麻岩成分范围与分离结晶作用有关,那么角闪石则已是一种主要控制矿物相,整个片麻岩杂岩可以在地壳深部高PH2O条件下演化而来。然而包含着初源物质的角闪岩,特别是柘榴角闪岩的部分熔融模式,看来是最能解释地球化学特征和野外关系的。片麻杂岩的较深部分在地壳矿物相生成时或稍后,转化为干的麻粒岩相组合,可能相应有变化的流体成分（富CO2）。驱逐含水流体要伴随着K、Rb、Th和U的丢失,从而增进了片麻岩杂岩的英云闪长质一奥长花岗质的特点。

关键词：闪长质片麻岩英云闪长岩云闪奥长花岗质片麻岩奥长花岗岩更长花岗岩角闪岩相片麻岩区花岗质重稀土钇族元素稀土族角闪石链状硅酸盐矿物稀土元素 ⅢB族元素麻粒岩相变质相麻粒岩区流体成分格陵兰丹麦地球化学地球科学太古宙太古代前寒武纪苏格兰

成年大鼠纹状体区α-羟甲基恶唑丙酸型受体亚单位谷氨酸受体1的研究

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上海医学 2007年第6期30卷 450-452,F0003页

作者：巴茂文刘振国孔敏陈生弟陆国强上海交通大学医学院附属新华医院神经内科 200092 上海交通大学医学院附属瑞金医院神经内科

目的研究膜α-羟甲基恶唑丙酸型(AMPA)受体亚单位谷氨酸受体1(GluR1)及其磷酸化形式在大鼠纹状体中的表达。方法采用Western印迹法、免疫组织化学法检测纹状体AMPA受体亚单位GluR1表达及磷酸化状态。结果纹状体有GluR1的表达,GluR1有(30... 详细信息

目的研究膜α-羟甲基恶唑丙酸型(AMPA)受体亚单位谷氨酸受体1(GluR1)及其磷酸化形式在大鼠纹状体中的表达。方法采用Western印迹法、免疫组织化学法检测纹状体AMPA受体亚单位GluR1表达及磷酸化状态。结果纹状体有GluR1的表达,GluR1有(30．00±4．36)%的磷酸化胞内羧基端831位丝氨酸(GluR1s831)和(31．00±1．56)%的磷酸化胞内羧基端845位丝氨酸(GluR1s845)形式表达;GluR1以及磷酸化GIuR1s831和磷酸化GluR1s845主要在纹状体背外侧区表达,所有小清蛋白阳性的神经元均表达GluR1以及磷酸化GluR1s831和磷酸化GluR1s845,且所有GluR1以及磷酸化GluR1s831和磷酸化GluR1s845阳性的神经元均为小清蛋白阳性的神经元。结论AMPA受体亚单位GluR1独特地在纹状体小清蛋白阳性的神经元表达,且存在明显磷酸化GluR1s831和磷酸化GluR1s845表达,为深入研究病理情况下AMPA受体的特性奠定了基础。

关键词： α-羟甲基恶唑丙酸型 Western印迹法磷酸化小清蛋白

自身攻丝与非自身攻丝皮质骨螺钉固定的显微结构改变和应力分布的观察(摘要)

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吉林大学学报(医学版) 1987年第1期 96-96页

作者：徐莘香达沃士 Rahn ba Cordey j Tepic s Perren sM 瑞士科学院实验外科研究所白求恩医科大学一院骨科

为了解自身攻丝与非自身攻丝螺钉固定对骨结构的影响及拧钉和紧固过程中应力分布的变化,我们进行了两种皮质骨螺钉固定后骨结构的扫描电镜观察和两种螺钉拧入及紧固后的光弹模型观察。在扫描电镜观察中,先以两个临近打孔测试的最大扭矩(... 详细信息

为了解自身攻丝与非自身攻丝螺钉固定对骨结构的影响及拧钉和紧固过程中应力分布的变化,我们进行了两种皮质骨螺钉固定后骨结构的扫描电镜观察和两种螺钉拧入及紧固后的光弹模型观察。在扫描电镜观察中,先以两个临近打孔测试的最大扭矩(Mmax)的75～85％的扭矩于两测试孔间中点准备标本。结果显示自身攻丝钉孔Zimmer钉(3.5mm)组2孔4个标本均可见裂纹,其中一孔两个标本可见骨螺纹变形;Howmedica钉(3.6mm)/组(2.8mm钻孔)4孔8个标本均发现有骨裂;Howmedica钉2组

关键词：攻丝螺钉骨结构紧固紧固件应力分布裂隙骨折骨裂自身

Densities, Ultrasonic speeds, Viscosities and Refractive Indices of Binary Mixtures of Benzene with Benzyl Alcohol,Benzonitrile, Benzoyl Chloride and Chlorobenzene at 303.15 K

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Chinese journal of Chemistry 2005年第4期23卷 377-385页

作者： ALI,A. PANDEY,j.D. sONI,N.K. NAIN,A.K. LAL,B. CHAND,D. DepartmentofChemistry JamiaMilliaIslamia(CentralUniversity)NewDelhi110025India DepartmentofChemistry UniversityofAllahabadAllahabad211002U.P.India

Densities, ρ, ultrasonic speeds, u , viscosities, η , and refractive indices, n , of pure benzene, benzyl alcohol (ba), benzonitrile (BN), benzoyl chloride (BC), chlorobenzene (CB) and their thirty six binary mixtures, with benzene as common component, were measured at 303.15 K over the entire mole fraction range. From these experimental data the values of deviations in ultrasonic speed, Δ u , isentropic compressibility, Δk s , excess acoustic impedance, Z E , deviation in viscosity, Δη, and excess Gibbs free energy of activation of viscous flow, G *E , and partial molar isentropic compressibility, of ba, BN, BC and CB in benzene were computed. The variation of these derived functions with composition of the mixtures suggested the increased cohesion (molecular order) in the solution and that interaction (A‐B)>(A‐A) or (B‐B). Moreover, theoretical prediction of ultrasonic speed, viscosity and refractive index of all the four binary mixtures was made on the basis of empirical and semi‐empirical relations by using the experimental values of the pure components. Comparison of theoretical results with the experimental values was made in order to assess the suitability of these relations in reproducing the experimental values of u , η and n . Also, molecular radii of pure liquids and the average molecular radii of binary mixtures were evaluated using the corresponding refractive indices of pure liquids and binary mixtures. The average molecular radii of binary mixtures were found to be additive with respect to mole fraction of the pure component.

关键词： binary mixture excess function density ultrasonic speed viscosity refractive index

羊膜移植治疗继发于LOC综合征的眼表瘢痕患者的随访研究

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世界核心医学期刊文摘（眼科学分册） 2005年第11期1卷 20-21页

作者： Moore j.E. shah s. KumarV. 桑延智 Department of Ophthalmology Roy al Victoria Hospital Grosvenor Road Belfast BT12 6BA United Kingdom

Aims: To document and discuss the long term outcome of a new ophthalm ic treatment for laryngo-onycho-cutaneous (LOC)-syndrome. Methods: Two children were treated by excision of ocular gran ulation tissue and ocular surface rehabilitation with frozen amniotic membrane ( AM). The clinical course of both patients was followed and documented at 2 years and 4 years following the surgery. Results: Patient 1 demonstrated limited recu rrence of granulation tissue at 10 months. After 36 months, re-growth of granul ation and scar tissue required a further three subsequent operations to the righ t eye in an attempt to keep the optical axis clear. 4 years postoperatively, nei ther eye has a clear visual axis. In contrast similar surgery for the right eye of patient 2 has been highly successful, with only very limited nonprogressive r ecurrence after 2 years of followup. The operation to the left eye has been simi larly effective although the followup is only 6 months. Conclusions: Ocular surf ace rehabilitation with AM is the first partially effective treatment for the ey e complications of LOC syndrome. The surprising benefit from AM may stem from th e primary pathology of the condition. LOC syndrome is caused by a genetic defect resulting in an unusual N-terminal deletion of the α3a chain of the basement membrane protein laminin 5. One mechanism through which AM transplantation may a ct to reduce ocular scarring in this disease is to supplement the abnormal secre ted laminin 5 with healthy transplanted laminin. Despite its initial efficacy on e episode of AM treatment does not guarantee long term control of the scarring p rocess and variations in AM graft efficacy may be related to other complicating factors such as limbal stem cell deficiency or severity of the initial scarring process.

关键词：羊膜移植治疗 LOC 随访研究眼表重建瘢痕化角膜缘干细胞眼科治疗视轴非进行性层黏连蛋白

脂质组学改善传统危险因素预测的2型糖尿病患者的心血管事件

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中华高血压杂志 2016年第10期24卷 905-905页

作者：刘莉叶鹏 Alshehry ZH Mundra Pa.ba.low CK Mellett NA Wong G McConville Mj simes j Tonkin AM sullivan DR barnes EH Nestel Pj Kingwell ba Marre M Neal B Poulter NR Rodgers A Williams B Zoungas s Hillis Gs Chalmers j Woodward M Meikle Pj

临床脂质测定并未显示出糖尿病或心血管病相关的脂质代谢改变的复杂性。脂质组学则能够评估可作为疾病风险潜在标志物的数百种脂质种类。方法：纳入来自糖尿病治疗和血管保护行动。

关键词： 2型糖尿病心血管事件脂质危险因素患者预测代谢改变心血管病

全氧条件下生物质和塑料共燃烧的热重分析及动力学

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过程工程学报 2016年第6期16卷 1022-1027页

作者：巴飞胡建杭刘慧利汤翔宇刘泽伟昆明理工大学冶金节能减排教育部工程研究中心云南昆明650093

以塑料(PVC)和木屑为原料模拟可燃固体废弃物中主要成分,采用Freeman-Carroll法根据优化的数学函数和动力学参数建立动力学模型,研究在全氧条件下生物质和塑料(塑料质量比15%,25%和50%)共燃烧的特性及动力学,对比了木屑和塑料单独燃烧... 详细信息

以塑料(PVC)和木屑为原料模拟可燃固体废弃物中主要成分,采用Freeman-Carroll法根据优化的数学函数和动力学参数建立动力学模型,研究在全氧条件下生物质和塑料(塑料质量比15%,25%和50%)共燃烧的特性及动力学,对比了木屑和塑料单独燃烧的情况,结果表明,随试样中塑料比例增加,TG-DTG曲线逐渐向低温区移动,挥发分失重峰温逐渐降低,固定碳失重峰逐渐增加.起始温度和最大燃烧速率对应的温度逐渐降低,终止温度增大.随塑料含量增加,计算的平均活化能逐渐增加,分别为52.46,63.05和70.91k j/mol,表明燃烧的难度逐渐增大,对外加能量的需求量也越大.燃烧特性指数逐渐减小,即加入塑料能降低木屑的燃烧温度.可燃固体废弃物中生物质含量多时易燃烧,塑料多时不易燃烧.

关键词：固体废弃物全氧燃烧热重分析动力学

Larvicidal efficacy of monoterpenes against the larvae of Anopheles gambiae

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Asian Pacific journal of Tropical Biomedicine 2016年第4期6卷 290-294页

作者： Eliningaya j.Kweka Tamires Cardoso Lima Chrian M.Marciale Dami?o Pergentino de sousa Division of Livestock and Human Diseases Vector Control Tropical Pesticides Research Institute Department of Medical Parasitology and Entomology Catholic University of Health and Allied Sciences Department of Pharmacy Federal University of Sergipe Department of Pharmaceutical sciences Federal University of Paraíba

Objective:To evaluate the larvicidal efficacy of eight volatile components of essential oils against 3rd instar larvae of Anopheles gambiae ***:Larvicidal effects of each compound were evaluated in both laboratory and semi-field *** solution was prepared and serial dilutions were made in six concentrations for each compound.A total of 20 larvae were exposed to larvicides for each replicate and monitored at intervals of 12,24,48 and 72 *** monitoring was done on basis of dead and live larvae in all ***:All assayed compounds were larvicides and presented varying degrees of larval toxicity,with LC50 values ranging from 1.28 to 1 938.92 mg/L depending on the treatment time(12,24,48 or 72 h).(-)-Perillyl alcohol presented the strongest larvicidal activity towards Anopheles gambiae larvae,with LC_(50) values of 73.60,18.36,1.72 and1.28 mg/L after 12,24,48 and 72 h of exposure,*** next strongest were(-)-isopulegol(LC_(50)= 135.10,49.39,34.39 and 20.22 mg/L) and(-)-carvone epoxide(LC_(50)= 168.86,124.74,80.84 and 23.46 mg/L).After 12,24 and 48 h of treatment,hydroxydihydrocarvone was the least toxic compound,with LC_(50) values of 1 938.92,1 172.18 and 401.03 mg/L,***:The data obtained in this study suggest that all evaluated monoterpenes,especially(-)-perillyl alcohol,have remarkable larvicidal effects and may be considered as potential sources for the development of suitable natural larvicides for mosquito management *** small-scale field trials should be conducted.

关键词： Larvicidal activity Malaria Anopheles gambiae s.s. Essential oils Monoterpenes Natural products Mosquito

影响P2Z受体介导慢性淋巴细胞白血病细胞凋亡的各种因素及其机理研究

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华西医科大学学报 2001年第2期32卷 208-212页

作者：彭黎明张芹江虹 Christopher j Bradely james s Wiley 华西医科大学附属第一医院检验科成都610041 澳大利亚墨尔本大学医学院Austin&Repatriation医学中心血液科

目的　探讨嘌呤能 P2 Z受体介导慢性淋巴细胞白血病 (CL L )细胞凋亡的影响因素及其机理。方法　在二价阳离子—— 1.0 mm ol/L Mg2 + 、Zn2 + 、Ca2 + 、sr2 + 、Co2 + 、ba2 + ,不同浓度的 EDTA或 EGTA,不同温度及在含 15 0 mm ol/L... 详细信息

目的　探讨嘌呤能 P2 Z受体介导慢性淋巴细胞白血病 (CL L )细胞凋亡的影响因素及其机理。方法　在二价阳离子—— 1.0 mm ol/L Mg2 + 、Zn2 + 、Ca2 + 、sr2 + 、Co2 + 、ba2 + ,不同浓度的 EDTA或 EGTA,不同温度及在含 15 0 mm ol/L胆碱的介质中 ,将表达 P2 Z受体 [P2 Z(+) ]的 CL L细胞分别同 1.0 mm ol/L三磷酸腺苷 (ATP)或 0 .1m mol/L苯甲酰苯甲酸 ATP(Bz ATP)体外培养 8小时 ,以 DNA凝胶电泳、Td T法和流式细胞分析 (FCA )检测上述条件下细胞凋亡的诱导或抑制效应。结果　 Mg2 + 或 Ca2 + 能以剂量依赖性方式促进 ATP诱导 P2 Z(+)细胞凋亡 ,而 EDTA或 EGTA却以相反的方式抑制 P2 Z(+)细胞凋亡的发生 ;1.0 mm ol/L Zn2 + 可完全阻止 ATP诱导 P2 Z(+)细胞凋亡所产生的 DNA片段 ,但其它二价阳离子包括 1.0 mm ol/L sr2 + 、Co2 + 、ba2 + 却不影响 ATP的诱导 ;胆碱作为磷脂酶 D(PL D)的抑制剂 ,也可部分抑制 P2 Z(+)细胞凋亡产生的 DNA片段 ;当温度低于 10℃ ,可完全阻止 ATP诱导 P2 Z(+)细胞凋亡产生 DNA片段的发生。结论　 P2 Z受体介导 CL L细胞凋亡可能与核酸内切酶 ,PL D的参与密切相关。

关键词：受体嘌呤能P2Z 细胞凋亡慢性淋巴细胞白血病二价阳离子