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Comparison of the Anatomy and Adaptability of Reconstructed Teeth with Natural Teeth:An Innovative Approach in Forensic dentistry

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Journal of Forensic science and medicine 2024年第1期10卷 47-54页

作者： supra.a.s P m Tejaswi Ravikanth manyam mohan Kumar Pasupuleti swetha P Ramesh Kumar Budumuru department of Oral and maxillofacial Pathology Vishnu Dental CollegeBhimavaramAndhra PradeshIndia Vishnu dental College BhimavaramAndhra PradeshIndia department of Periodontics and Implantology Vishnu Dental CollegeBhimavaramAndhra PradeshIndia department of Oral medicine and Radiology Vishnu Dental CollegeBhimavaramAndhra PradeshIndia

Background:Forensic tooth reconstruction is the technique of reconstructing the morphology of a missing tooth from the intra-alveolar morphology of dental sockets from skeletal *** and Objectives:The aim and objective of the study are to compare and investigate whether the anatomy and adaptability of reconstructed teeth simulate with the natural tooth and to investigate whether the dental materials have potential in reconstruction of *** and methods:An in vitro experimental study was undertaken on a human *** to the Fédération dentaire Internationale,charting will be done based on the number of teeth *** entire study will be conducted in three phases using dental *** 1 comprised preparation for negative replica,where an impression will be taken,Phase 2 comprised preparation of a positive replica or cast,and Phase 3 comprised tooth reconstruction using the flowable ***:The specimen tooth(which had been taken from its socket)and the newly constructed tooth were compared,and when the length of the newly constructed root was measured using digital vernier calipers,there was a disparity of 0.5-1 *** cone-beam computed tomography radiographs demonstrated the necessary ***:The present study demonstrated that dental information can be obtained even when teeth are absent postmortem by making an attempt to recreate the teeth using dental materials while documenting the intra-alveolar anatomy of the dental root socket.

关键词： Adaptability anatomy reconstruction teeth

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solid-liquid extraction for yttrium recovery using porous polymeric resin(XAd-7) functionalized with d_(2)EHPA

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Journal of Rare Earths 2024年第9期42卷 1764-1773,I0005页

作者： P.A.martínez-montoya R.G.sanchez-Alvarado d.Y.medina-Velazquez m.L.Carrera-Jota P.Garnica-Chávez A.de J.morales-Ramirez Higher school of Chemical Engineering and Extractive Industries ESIQIEIPNDepartment of Metallurgical EngineeringUPALM S/NCol.LindavistaGustavo A.Madero Cd.de MéxicoC.P07738Mexico metropolitan Autonomous University Department of MaterialsBasic Sciences and EngineeringAv.San Pablo No.180Col.Reynosa TamaulipasCd.de MéxicoC.P02200Mexico Center for Research and Technological Innovation CIITECIPNCda.de CECATIs/nSanta CatarinaAzcapotzalcoC.P02250CDMXMexico

The recovery of yttrium is proposed by applying a solid-liquid extraction process using di-2-ethyl hexylphosphoric acid(d2EHPA) as extracting *** extracting agents were supported on a macro porous polymeric resin XAd-7(solid phase).Yttrium ions extraction and discharge tests were performed,firstly from a synthetic aqueous solution of 100 mg/L Y(liquid phase) at 25℃ with *** effects of pH of aqueous solutions bearing yttrium,volume fraction of extracting agents and the solid/liquid(s/L)ratio on the yttrium recovery were *** most favorable conditions for yttrium ions extraction are;20 vol% d_(2)EHPA functionalized resin,pH=1.5 and an s/L ratio of 10 mg/mL The discharge of yttrium ions was done under the same conditions of extraction stage,using a 2 mol/L [H_(2)sO_(4)] as stripping *** to 80% yttrium is extracted,while 75% yttrium is recovered in the striping *** all experiments,the reaction equilibrium is reached after 20 min,and the kinetics for the extraction stage was determined as a second-order ***,experiments were carried out to discharge the yttriumloaded resins,and it has been determined that the best pH value to strip the Y ions is *** tests of extraction and discharge for yttrium ions show that the functionalized resin can work at least five cycles without decreasing its ***,the proposed process was tested in a real solution with Y ions fro m a waste fluorescent la mp powder leached in H_(2)sO_(4),demonstrating the ability to effectively recover yttrium,separating it from various metals from the studied residue.

关键词： Yttrium recovery Rare earth solid-liquid extraction XAd-7 resin Fluorescent lamps recycling solid-liquid kinetics extraction

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Elucidating regulatory processes of intense physical activity by multi-omics analysis

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military medical Research 2024年第4期11卷 479-499页

作者： Ernesto s.Nakayasu marina A.Gritsenko Young-mo Kim Jennifer E.Kyle Kelly G.stratton Carrie d.Nicora Nathalie munoz Kathleen m.Navarro daniel Claborne Yuqian Gao Karl K.Weitz Vanessa L.Paurus Kent J.Bloodsworth Kelsey A.Allen Lisa m.Bramer Fernando montes Kathleen A.Clark Grant Tietje Justin Teeguarden Kristin E.Burnum-Johnson Biological sciences division Pacific Northwest National LaboratoryRichlandWA 99352USA Environmental and molecular sciences division Pacific Northwest National LaboratoryRichlandWA 99352USA Centers for disease Control and Prevention National Institute for Occupational Safety and HealthWestern States DivisionDenverCO 80204USA Computational Analytics division Pacific Northwest National LaboratoryRichlandWA 99352USA National security directorate Pacific Northwest National LaboratoryRichlandWA 99352USA Los Angeles County Fire department Los AngelesCA 90063USA Centers for disease Control and Prevention National Institute for Occupational Safety and HealthRespiratory Health DivisionMorgantownWV 26505USA Environmental and molecular Toxicology Oregon State UniversityCorvallisOR 97331USA

Background:Physiological and biochemical processes across tissues of the body are regulated in response to the high demands of intense physical activity in several occupations,such as firefighting,law enforcement,military,and sports.A better understanding of such processes can ultimately help improve human performance and prevent illnesses in the work ***:To study regulatory processes in intense physical activity simulating real-life conditions,we performed a multi-omics analysis of 3 biofluids(blood plasma,urine,and saliva)collected from 11 wildland firefighters before and after a 45 min,intense exercise *** profiles ***-exercise were compared by student’s t-test followed by pathway analysis and comparison between the different omics ***:Our multi-omics analysis identified and quantified 3835 proteins,730 lipids and 182 metabolites combining the 3 different types of *** blood plasma analysis revealed signatures of tissue damage and acute repair response accompanied by enhanced carbon metabolism to meet energy *** urine analysis showed a strong,concomitant regulation of 6 out of 8 identified proteins from the renin-angiotensin system supporting increased excretion of catabolites,reabsorption of nutrients and maintenance of fluid *** saliva,we observed a decrease in 3 pro-inflammatory cytokines and an increase in 8 antimicrobial peptides.A systematic literature review identified 6 papers that support an altered susceptibility to respiratory ***:This study shows simultaneous regulatory signatures in biofluids indicative of homeostatic maintenance during intense physical activity with possible effects on increased infection susceptibility,suggesting that caution against respiratory diseases could benefit workers on highly physical demanding jobs.

关键词： multi-omics analysis Intense exercise Human performance Biofluids metabolism Immunity

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Clinical validation of the early embryo viability assessment system: Analysis for the blastocyst morphology and pregnancy outcomes

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Asian pacific Journal of Reproduction 2024年第5期13卷 219-227页

作者： Vu d Hop An m Cuong Phi T T Anh Nguyen T L Huong Le Hoang Nguyen V Hanh Assisted Reproductive Technology Centre Tam Anh General HospitalHanoiVietnam Institute of Biotechnology Vietnam Academy of Science and TechnologyHanoiVietnam

Objective:To determine the relationship between the early embryo viability assessment(EEVA)and blastocyst morphological parameters and pregnancy ***:This retrospective cohort study was conducted on 291 intracytoplasmic sperm injection cycles including 2522 embryos with indications of prolonging embryo culture to the blastocyst stage in the Genea embryo review incubator,and 511 single vitrified-wa.m.d blastocyst transfer cycles from January 2020 to June *** EEVA system produced an EEVA score from E1(best)to E5(worse)for the potential of blastocyst *** morphology was *** association between the EEVA score and each type of blastocyst morphology,implantation rate,clinical pregnancy,and ongoing pregnancy were assessed using generalized estimating ***:The inner cell mass A(ICm A),trophectoderm A(TE A),blastocoele expansion degree of 3,4,5,6,7 rates were higher with lower the EEVA *** adjusted odd ratio(aOR)(E5 vs E1)was 0.3 for ICm A,0.174 for TE A and 0.210 for BL3,4,5,6,7(all Psuggesting a significant association between lower EEVA scores and improved embryo *** implantation,clinical pregnancy,and ongoing pregnancy rate were also higher with lower the EEVA *** aOR of E5 vs E1 was 0.245 for implantation,0.185 for clinical pregnancy and 0.200 for ongoing pregnancy rate(Psions:There were associations between blastocyst morphology,pregnancy outcome and EEVA *** good blastocyst morphology and pregnancy outcomes are higher with lower the EEVA score.

关键词： Automated embryo assessment Blastocyst Early embryo viability assessment Genea embryo review incubator

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Intraoperative application of three-dimensional printed guides in total hip arthroplasty: A systematic review

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World Journal of Orthopedics 2024年第7期15卷 660-667页

作者： Tim P Crone Bart m W Cornelissen Jakob Van Oldenrijk Pieter Koen Bos Ewout s Veltman department of Orthopedic surgery and sports medicine Erasmus Medical CenterRotterdam 3015 GDNetherlands department of Oral and maxillofacial surgery Erasmus Medical CenterRotterdam 3015 GDNetherlands

BACKGROUNd Acetabular component positioning in total hip arthroplasty(THA)is of key importance to ensure satisfactory post-operative outcomes and to minimize the risk of *** majority of acetabular components are aligned freehand,without the use of navigation *** specific instruments(PsI)and three-dimensional(3d)printing of THA placement guides are increasingly used in primary THA to ensure optimal *** To summarize the literature on 3d printing in THA and how they improve acetabular component *** Pubmed was used to identify and access scientific studies reporting on different 3d printing methods used in *** studies with 236 hips in 228 patients were *** studies could be divided into two main categories;3d printed models and 3d printed *** 3d printing in THA helped improve preoperative cup size planning and post-operative Harris hip scores between intervention and control groups(P=0.019,P=0.009).Otherwise,outcome measures were heterogeneous and thus difficult to *** overarching consensus between the studies is that the use of 3d guidance tools can assist in improving THA cup positioning and reduce the need for revision THA and the associated *** The implementation of 3d printing and PsI for primary THA can significantly improve the positioning accuracy of the acetabular cup component and reduce the number of complications caused by malpositioning.

关键词： Total hip arthroplasty Three-dimensional printing Hip replacement surgery Three-dimensional planning surgical guides

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study of boundary layer characteristics during the landfalling of a Nisarga cyclone

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TROPICAL CYCLONE REsEARCH ANd REVIEW 2024年第2期13卷 55-71页

作者： Pawar, Rani P. Priya.a.shini, Prajna dharmaraj, T. Nade, dada P. Patil, mahendra N. Patil, Omkar m. Victor, N. Jeni Pawar, sambhaji m. Kanase, d. G. Pawar, sunil d. Indian Inst Trop meteorol Minist Earth Sci Pune Maharashtra India Bharati Vidyapeeths dr Patangrao Kadam mahavidya Dept Phys Sangli India IIG KSK Geomagnet Res Lab Allahabad Uttar Pradesh India sanjay Ghodawat Univ Kolhapur Dept Phys Kolhapur India

One of the most important parameters in meteorology is the mean wind pro fi le in the tropical cyclone boundary layer. The vertical pro fi le of wind speed and wind direction were measured during the period of the Nisarga cyclone from may 31st, 2020, to June 5th, 2020, using the newly installed Phased Array doppler sodar system at the Center for space and Atmospheric science (CsAs), sanjay Ghodawat University, Kolhapur (16.74 degrees N, 74.37 degrees E; near India ' s western coast). Our analysis revealed that the maximum mean wind speed was 17 m/s on June 3, 2020, at 10:00 IsT. It also shows the change in wind direction from southwest to southeast on June 2 and 3, 2020. daily high-resolution reanalysis data in the domain, 0 - 25 degrees N, 65 - 110 degrees E, during the period from may 31st to June 5th, 2020, revealed the variation of the atmospheric pressure of the Nisarga cyclone from 1000 to 1008 hPa, sea surface temperature (ssT) between 30 degrees C and 31 degrees C, outgoing longwave radiation (OLR) between 100 and 240 Wm-2 , wind speed between 3 and 15 m/s, and low values of vertical wind shear (VWs) were observed to the north of Nisarga track. These observations may provide more insights for the study of boundary layer turbulence during cyclonic activities. (c) 2024 The shanghai Typhoon Institute of China meteorological Administration. Publishing services by Elsevier B.V. on behalf of KeAi Communication Co. Ltd. This is an open access article under the CC BY license (http://***/licenses/by/4.0/).

关键词： Phased Array doppler sodar Tropical cyclone Atmospheric boundary layer Vertical turbulence intensity VERTICAL WINd sHEAR TROPICAL CYCLONEs sOdAR OBsERVATIONs GRAVITY-WAVEs PERsPECTIVEs TEmPERATURE INTENsITY mONsOON BENGAL BAY

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In vivo femtosecond laser nanosurgery of the cell wall enabling patch-clamp measurements on filamentous fungi

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microsystems & Nanoengineering 2024年第2期10卷 251-267页

作者： Tanja Pajić Katarina stevanović Nataša V.Todorović Aleksandar J.Krmpot miroslav Živić svetla.a.savić-Šević steva m.Lević marina stanić dejan Pantelić Brana Jelenković mihailo d.Rabasović Institute of Physiology and Biochemistry“Ivan djaja” Faculty of BiologyUniversity of BelgradeStudentski trg 1611158BelgradeSerbia Institute for Biological Research“siniša stanković” University of BelgradeNational Institute of the Republic of SerbiaBulevar Despota Stefana 14211000BelgradeSerbia Institute of Physics Belgrade University of BelgradeNational Institute of the Republic of SerbiaPregrevica 11811080BelgradeSerbia University of Belgrade Faculty of AgricultureNemanjina Street 611080BelgradeSerbia Institute for multidisciplinary Research University of BelgradeKneza Višeslava 111030BelgradeSerbia

studying the membrane physiology of filamentous fungi is key to understanding their interactions with the environment and crucial for developing new therapeutic strategies for disease-causing ***,their plasma membrane has been inaccessible for a micron-sized patch-clamp pipette for pA current recordings due to the rigid chitinous cell ***,we report the first femtosecond IR laser nanosurgery of the cell wall of the filamentous fungi,which enabled patch-clamp measurements on protoplasts released from hyphae.A reproducible and highly precise(diffraction-limited,submicron resolution)method for obtaining viable released protoplasts was *** release from the nanosurgery-generated incisions in the cell wall was achieved from different regions of the *** plasma membrane of the obtained protoplasts formed tight and high-resistance(GΩ)contacts with the recording *** entire nanosurgical procedure followed by the patch-clamp technique could be completed in less than 1 *** to previous studies using heterologously expressed channels,this technique provides the opportunity to identify new ionic currents and to study the properties of the ion channels in the protoplasts of filamentous fungi in their native environment.

关键词： patch recording laser

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Role of marine natural products in the development of antiviral agents against sARs‑CoV‑2:potential and prospects

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marine Life science & Technology 2024年第2期6卷 280-297页

作者： d.P.Nagahawatta N.m.Liyanage Thilina U.Jayawardena H.H.A.C.K.Jayawardha.a.seong‑Hun Jeong Hyung‑Jun Kwon You‑Jin Jeon department of marine Life sciences Jeju National UniversityJeju 690-756Republic of Korea department of Chemistry Biochemistry and PhysicsUniversitédu QuébecàTrois-RivièresTrois-RivièresQC G8Z 4M3Canada marine science Institute Jeju National UniversityJeju 63333Republic of Korea Functional Biomaterial Research Center Korea Research Institute of Bioscience and BiotechnologyJeongeup-siRepublic of Korea

A novel coronavirus,known as severe acute respiratory syndrome coronavirus 2(sARs-CoV-2),has surfaced and caused global concern owing to its ***-CoV-2 is the causative agent of coronavirus disease 2019;however,it was only discovered at the end of the year and was considered a pandemic by the World Health ***,the develop-ment of novel potent inhibitors against sARs-CoV-2 and future outbreaks is urgently *** naturally occurring bioactive substances have been studied in the clinical setting for diverse *** intricate infection and replication mechanism of sARs-CoV-2 offers diverse therapeutic drug targets for developing antiviral medicines by employing natural products that are safer than synthetic *** natural products(mNPs)have received increased attention in the development of novel drugs owing to their high diversity and ***,this review article investigates the infection and replication mechanisms,including the function of the sARs-CoV-2 genome and ***,we highlighted anti-sARs-CoV-2 therapeutic intervention efforts utilizing mNPs and predicted sARs-CoV-2 inhibitor design.

关键词： sARs-CoV-2 marine natural products drug targets Inhibitors

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Extracellular vesicles-coupled miRNAs from oviduct and uterus modulate signaling pathways related to lipid metabolism and bovine early embryo development

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Journal of Animal science and Biotechnology 2024年第4期15卷 1528-1549页

作者： Rosane mazzarella Karina Canon‑Beltran Yulia N.Cajas meriem Hamdi Encina m.Gonzalez Juliano C.da silveira Claudia L.V.Leal d.Rizos department of Animal Reproduction INIA-CSICMadridSpain department of Biochemistry and molecular Biology Veterinary FacultyComplutense University of Madrid(UCM)MadridSpain department Agrarian Production Technical University of MadridUPMMadridSpain departamento de Ciencias Biologicas Universidad Tecnica Particular de LojaUTPLLojaEcuador department of Anatomy and Embryology FV-UCMMadridSpain department of Veterinary medicine FZEA-USPPirassunungaBrazil

Background Extracellular vesicles(EVs) present in oviductal(OF) and uterine fluid(UF) have been shown to enhance bovine embryo quality during in vitro culture by reducing lipid contents and modulating lipid metabolism-related genes(LmGs), while also influencing cell proliferation, suggesting their involvement on the regulation of different biological pathways. The regulation of signaling pathways related to cell differentiation, proliferation, and metabo-lism is crucial for early embryo development and can determine the success or failure of the pregnancy. Bioactive molecules within EVs in maternal reproductive fluids, such as micro RNAs(miRNAs), may contribute to this regulatory process as they modulate gene expression through post-transcriptional *** This study evaluated miRNA cargo in OF-EVs from the early luteal phase and UF-EVs from the mid-luteal phase, coinciding with embryo transit within oviduct and uterus in vivo, and its possible influence on LmGs and sign-aling pathways crucial for early embryo development. A total of 333 miRNAs were detected, with 11 exclusive to OF, 59 to UF, and 263 were common between both groups. From the 20 differentially expressed miRNAs, 19 up-regulated in UF-EVs(bta-miR-134, bta-miR-151-3p, bta-miR-155, bta-miR-188, bta-miR-181b, bta-miR-181d, bta-miR-224, bta-miR-23b-3p, bta-miR-24-3p, bta-miR-27a-3p, bta-miR-29a, bta-miR-324, bta-miR-326, bta-miR-345-3p, bta-miR-410, bta-miR-652, bta-miR-677, bta-miR-873 and bta-miR-708) and one(bta-miR-148b) in OF-EVs. These miRNAs were predicted to modulate several pathways such as Wnt, Hippo, mAPK, and lipid metabolism and degradation. differ-ences in miRNAs found in OF-EVs from the early luteal phase and UF-EVs from mid-luteal phase may reflect differ-ent environments to meet the changing needs of the embryo. Additionally, miRNAs may be involved, particularly in the uterus, in the regulation of embryo lipid metabolism, immune system, and *** Our study su

关键词： Embryo-maternal interaction Epigenetic Exosomes mammalian Preimplantation Reproductive fluids

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Lattice Boltzmann method formulation for simulation of thermal radiation effects on non-Newtonian Al_(2)O_(3) free convection in entropy determination

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Applied mathematics and mechanics(English Edition) 2024年第6期45卷 1085-1106页

作者： m.NEmATI m.sEFId A.KARImIPOUR A.J.CHAmKHA Faculty of mechanical Engineering Yazd UniversityYazd ***Iran department of mechanical Engineering Najafabad BranchIslamic Azad UniversityNajafabad ***Iran Faculty of Engineering Kuwait College of Science and TechnologyDoha 35004Kuwait

The simultaneous investigation on the parameters affecting the flow of electrically conductive fluids such as volumetric radiation,heat absorption,heat generation,and magnetic field(mF)is very vital due to its existence in various sectors of industry and *** present research focuses on mathematical modeling to simulate the cooling of a hot component through power-law(PL)nanofluid convection *** temperature reduction of the hot component inside a two-dimensional(2d)inclined chamber with two different cold wall shapes is *** formulation of the problem is derived with the lattice Boltzmann method(LBm)by code writing via the FORTRAN *** variables such as the radiation parameter(0–1),the Hartmann number(0–75),the heat absorption/generation coefficient(−5–5),the fluid behavioral index(0.8–1.2),the Rayleigh number(103–105),the imposed mF angle(0°–90°),the chamber inclination angle(−90°–90°),and the cavity cold wall shape(smooth and curved)are *** findings indicate that the presence of radiation increases the mean Nusselt number value for the shear-thickening,Newtonian,and shear thinning fluids by about 6.2%,4%,and 2%,*** most cases,the presence of nanoparticles improves the heat transfer(HT)rate,especially in the cases where thermal conduction dominates *** is the lowest cooling performance index and mF effect for the cavity placed at an angle of 90°.The application in the design of electronic coolers and solar collectors is one of the practical cases of this numerical research.

关键词： thermal performance analysis heat absorption/generation power-law(PL)Al_(2)O_(3)nanofluid magnetohydrodynamics natural convection volumetric radiation inclined cavity

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