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Open Journal of Fluid Dynamics 2022年第1期12卷 96-126页

作者： Moussa diop Denis Flick Graciela Alvarez Jean Moureh Refrigerating Process Engineering Unit INRAE Antony Antony France UMR SayFood AgroParisTech INRAE Université Paris Saclay Massy France

This paper investigated lateral diffusion of a confined two-dimensional wall jet (air inlet height: 5 cm) through a perforated plate. We considered two plates with porosities of and . The plates were positioned at distances of 10 cm and 20 cm below the jet inlet. The experiments were realized using 2D Laser Doppler Anemometer (LDA). Different profiles of mean and fluctuating velocities are presented. The presence of a perforated plate strongly modified the airflow pattern compared to an empty enclosure. The velocities above and below the plate depend on several parameters, including the porosity and the plate’s position relative to the inlet slot and the longitudinal position. The difference between the flow velocity above and below the plates could not be related using a universal formula that depends on these parameters. We also investigated the influence of a porous media of a height of 20 cm (a stack of spheres having a diameter of 3.75 cm) located below the perforated plate. The results highlight that the porous medium strengthens the effects of the perforated plate on the flow.

关键词： Porous Medium Perforated Plate Wall Jet Air Ventilation Aeraulic Turbulence Diffusion

Determinants of the Use of Health Care and Therapeutic Routes of Populations in Rural Senegalese Areas, 2016

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Open Journal of Preventive Medicine 2021年第12期11卷 439-448页

作者： Abdoul Aziz Ndiaye Awa Ba-diop Maimouna diop Alioune Badara Tall ousseynou Ka Fatou Ndiaye Omar Sy Sylla Ndeye Fatou Ngom Aladji Madior diop Lamine Gueye Anta Tal Dia Université Alioune diop de Bambey Bambey Senegal Université Cheikh Anta diop de Dakar Dakar Senegal

In Senegal, access to health care for rural populations and therapeutic choices remain problematic. These problems may be synonymous with insufficient financial resources, long waits, ineffective treatments, or drug shortage in health structures, leading patients to perform various therapeutic behaviours. The aim of this present study was to identify the therapeutic routes of the patients and the determinants of the different uses of health care in the populations of Ferlo. This descriptive and analytical study was carried out as part of the medical consultation days of the 2016 summer at the university in Widou Thiengoly. All patients who met the selection criteria were enrolled. In total, the 150 participants were mainly animal breeders (63.3%) and housewives (26%), also, most were women (90.7%). The analysis of the therapeutic routes showed that the health post was used as first-line and second-line respectively in 85.3% and 59.3% of the study populations. Traditional medicine and self-medication would be used in the third intention. Therapeutic choices were independent of age (p = 0.94), marital status (p = 0.84) and occupation (p = 0.58). On the other hand, social dimensions, such as tradition, appreciation of efficiency, distance, cost, and gender, also determine the use of health care. Women used health post more frequently than men (p = 0.03) (OR: 3.89, CI95% [1.16 - 12.98]) of the order 3.89. The main reasons for self-medication practice were the treatment of headache or fever (46%) and that of fatigue (26%). The prices were more expensive for health facilities (70.9%) than for traditional healers (70% “not expensive at all”) where the waiting time was considered “not long at all” (70%).

关键词： Therapeutic Routes Biomedicine Traditional Medicine Widou Thiengoly

Iron in Water: Study of Iron Removal Kinetics in Chemically Reconstituted Waters: Application to Groundwater of South Pout (PS2 Site)

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Open Journal of Metal 2021年第1期11卷 1-10页

作者： Faye Ma.a.ou Sambe Falilou Mbacké diop El Hadji Moussa Toure Alpha ousmane Mbaye Fall Aminata diop Mar Codou Guèye Laboratory of Electrochemistry and Membrane Process Ecole Supérieure Polytechnique Cheikh Anta Diop University Dakar Senegal Quality Control Analysis Laboratory of the Senegalese Water Company (SWC) Dakar Senegal

The goal of this topic is a synthesis of the main characteristics of iron in groundwater and the oxidation process used to remove it. Indeed, the kinetics of chemical oxidation of iron (II) was examined with reconstituted water (distilled water + iron sulphate) and proceeded to the application in the groundwater samples taken from South Pout (Senegal) precisely in the drilling PS2. The sources of iron are natural or anthropogenic. In Senegalese waters, its content is variable and sometimes exceeds the standards of potability. Despite the diversification of iron removal process, chemical oxidation is the most used solution in drinking water treatment plants in Senegalese rural areas. Applied oxidation processes such as aeration and chlorination, however, are insufficient to produce drinking water with an iron concentration in accordance with standards of potability.

关键词： Iron Kinetics Chemical Oxidation Groundwater Drilling

What Impact on Phenotype for Patients with Karyotype 46, XX DSD SRY Positive at CHU Dantec in Senegal: About 5 Cases?

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Open Journal of Genetics 2023年第2期13卷 83-96页

作者： Fatou diop Gueye Arame Ndiaye Adji Dieynaba Diallo Mame Venus Gueye Ndiaga diop Macoura Gadji oumar Faye Mama Sy Diallo Cytogenetics Unit Laboratory of Clinical Cytology-Cytogenetics-Biology of Reproduction and Human Development Aristide Le Dantec Hospital Dakar Senegal Doctoral School of Life Health and Environmental Sciences ED-SEV Human Biology and Pathology Faculty of Medicine Pharmacy and Odontology Cheikh Anta Diop University Dakar Senegal Histology-Embryology Laboratory Department of Biology and Functional Explorations Faculty of Medicine Pharmacy and Odontology Cheikh Anta Diop University Dakar Senegal Sciences Biologiques et Pharmaceutiques Appliquées Université Cheikh Anta Diop Dakar Senegal

Background: In disorders of sexual differentiation, sexual development may not conform to the chromosomal structure, thus forming different types of abnormalities. Among these abnormalities is syndrome 46, XX DSD where most patients are female phenotype with clitoral hypertrophy that can go to complete masculinization especially in the presence of the SRY gene. Objective: The goal of this work is to demonstrate a relationship between the genotype and the phenotype in five patients karyotype 46, XX with the presence of the SRY gene. Methodology: The study involves five patients referred to the laboratory under suspicion of sexual development anomalies. The diagnosis took place through hormonal and echography examinations, a classic cytogenetic study (Barr chromatin and karyotype) and an amplification of the SRY gene located on the Y chromosome. The resulting PCR products were sent for sequencing. Results: Based on the results of clinical and paraclinical tests carried out it was found clitoral hypertrophy, the presence of clitoris penis for some, presence of normal penis for others. In addition, echography revealed a lack of female internal genitalia (P2, P3), and a presence of testicles (P3, P4, P5). Genetic analysis (chromosomal and molecular) showed a karyotype 46, XX SRY (+) for all patients. New mutations were found c.246 T > A, p.82 Asn82Lys and c.171 G > C, p.57 Gln57His. Conclusion: In our study, we were able to correlate each DSD with karyotype 46, XX to a pathology such as 46, XX DSD testicular, 46, XX DSD with clitoral hypertrophy and ovotestis 46, XX. The next step will undoubtedly be the integration of other molecular techniques (genotyping, FISH, CGH or even the CGH array) to further genetic exploration.

关键词： 46 XX DSD SRY Phenotype Hypertrophy

Harmonizing the COVID-19 sample biobanks: Barriers and opportunities for standards, best practices and networks

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Biosafety and Health 2022年第4期4卷 280-282页

作者： Balwir Matharoo-Ball Mbayame diop Zisis Kozlakidis Director of Biobank G42 HealthcareAbu DhabiUnited Arab Emirates UniversitéCote d’Azur Nice 06100France International Agency for Research on Cancer World Health Organization69372 Lyon CEDEX 08France

The coronavirus disease 2019(COVID-19)pandemic has highlighted the practice of infectious diseases biobanking,as well as existing challenges and ***,the future of infectious diseases biobanking in the post-pandemic era,shall not be an“entry-level version”of its counterpart in non-communicable diseases and large population cohorts,but incorporate the lessons *** constitute a critical research infrastructure supported by harmonized practices through the implementation of international standards,and perceived within the broader scope of healthcare's intersection with *** perspective paper considers the barriers in biobanking and standardization of practices,as well as the emerging opportunities in the field.

关键词： Biobanks COVID-19 Biobank standards Biobank best practices Biobank networks

High Field MRI in Human African Trypanosomiasis (HAT)

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Open Journal of Radiology 2017年第3期7卷 190-198页

作者： Cherif Moha.a.ou Aidara Caroline Magne Philomene Kouna Gaelle Ebinda Mipinda Abdoulaye Dione diop Abdoulaye Ndoye diop Sokhna Ba Radiology Office of Fann University Hospital Dakar-Fann Sénégal Internal Medecine Office of Polyclinique El Rapha Trois Quartiers Libreville Gabon Radiology Office of Polyclinique El Rapha Trois Quartiers Libreville Gabon

Human African Trypanosomiasis (HAT) or sleeping thickness is a forest and rural disease;where agriculture is the main activity. It is a chronic and lethal disease without treatment. HAT is caused by two parasites;Trypanosoma Brucei Gambiense (gTB) and Trypanosoma Brucei Rhodesiense (rTB) transmitted to humans by the tsetse fly. It is endemic condition in Africa between the 15° north latitude and the 20° south latitude. It is reported outside this area in travelers who stayed in endemic zone. Infection by gTB is wider and more frequent (98%) than that by rTB (2%). The Democratic Republic of Congo is the most affected country with more than 75% of reported cases. The geographical distribution is not homogeneous. There are more affected regions in a zone called “foci” which represents areas favorable to the development of the vector. Its diagnosis and treatment are very important because of its social and economic impact at both the individual and community levels. Promising molecules including fexinidazole are currently undergoing testing. Nowadays populations move more and more easily but the discovery of this disease in daily neuroradiological practice is exceptional. We propose in this paper through two observations, reminders on epidemiological, clinical and MRI features of HAT. It typically performs the edematous, bilateral and diffuse encephalitis. It is important to distinguish these aspects from the arsenic-induced encephalitis that may occur during treatment. Only vector control allows eradicating this disease. WHO has set targets elimination of HAT as a public health problem for 2020 deadline.

关键词： Human African Trypanosomiasis High Field MRI Diffuse Encephalitis Optic Tract Arsenic-Induced Encephalitis

Assessment of Poultry Feed Contamination Level by Aflatoxin B1: Quantification by Two Chromatographic Analysis Methods

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Food and Nutrition Sciences 2022年第11期13卷 950-961页

作者： Rokhaya Gueye Viviane Chatchueng Sandefo Babacar Beye Elhadji ousmane Faye a.a.ou diop Serigne Omar Sarr Bara Ndiaye Yérim Mbagnick diop Laboratoire de Chimie Analytique et Bromatologie Faculté de Médecine de Pharmacie et d’Odontologie-Stomatologie Université Cheikh Anta DIOP Dakar Sénégal Laboratoire de Mycotoxines Institut de Technologie Alimentaire Route des Pères Maristes Dakar Sénégal

Aflatoxin B1 is a mycotoxin that can contaminate a wide feedstuffs variety. Ingestion of contaminated feed by poultry can lead to impaired health and zootechnical performances but also a human diet safety problem related to residues presence in animal origin products. Aflatoxin B1 contamination of poultry feed samples marketed in Dakar city and in peri-urban areas (Gorom, Sangalkam) was studied. A total of 15 samples were collected from Dakar city markets as well as from poultry farms in Gorom and Sangalkam areas. Aflatoxin B1 quantification was performed by high performance liquid chromatography and thin-layer chromatography. HPLC results showed that all samples were contaminated with levels ranging from 0.15 to 22 ppb, 0.099 to 2.05 ppb and 0.099 to 4.95 ppb respectively for Gorom, Sangalkam and Dakar. Only the finishing feed from Gorom had an aflatoxin B1 level above the maximum limit set by regulations. TLC is a suitable method for aflatoxins detection. However, it was associated with overestimation for aflatoxin B1 quantification. Results suggest that poultry feed represents a real source of human diet contamination. In addition, HPLC remains the most reliable quantification technique for quality control.

关键词： Poultry Feed Aflatoxin High Performance Liquid Chromatography Thin-Layer Chromatography Dakar

AC Back Surface Recombination Velocity in n<sup>+</sup>-p-p<sup>+</sup>Silicon Solar Cell under Monochromatic Light and Temperature

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Journal of Electromagnetic Analysis and Applications 2021年第5期13卷 67-81页

作者： Mame Faty Mbaye Fall Idrissa Gaye Dianguina Diarisso Gora diop Khady Loum Nafy diop Khalidou Ma.a.ou Sy Mor Ndiaye Gregoire Sissoko Ecole Polytechnique de Thiès Thiès Sénégal Institute of Technology University of Thiès Thiès Sénégal Laboratory of Semiconductors and Solar Energy Physics Department Faculty of Science and Technology University Cheikh Anta Diop Dakar Senegal

Excess minority carrier’s diffusion equation in the base of monofaciale silicon solar cell under frequency modulation of monochromatic illumination is resolved. Using conditions at the base limits involving recombination velocities Sf and Sb, respectively at the junction (n+/p) and back surface (p+/p), the AC expression of the excess minority carriers’ density δ (T, ω) is determined. The AC density of photocurrent Jph (T, ω) is represented versus recombination velocity at the junction for different values of the temperature. The expression of the AC back surface recombination velocity Sb of minority carriers is deduced depending on the frequency of modulation, temperature, the electronic parameters (D (ω)) and the thickness of the base. Bode and Nyquist diagrams are used to analyze it.

关键词： Silicon Solar Cell AC Back Surface Recombination Velocity Temperature Bode and Nyquist Diagrams

Hydrogeochemical Relationships between Spring and Subsurface Waters in the Dindefello Area of South Eastern Senegal

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Journal of Water Resource and Protection 2014年第19期6卷 1743-1754页

作者： Seybatou diop Fary Diome Momar Samb Raphael Sarr Institute of Earth Sciences Faculty of Sciences and Techniques Cheikh Anta Diop University of Dakar Dakar Senegal Department of Geology Faculty of Sciences and Techniques Cheikh Anta Diop University of Dakar Dakar Senegal

The analytical results of water samples collected from the Dindefello Plain area revealed the dominant major ions of bicarbonate, silica, calcium, magnesium and sodium, in order of decreasing relative abundance. Spring water exhibited a very low, i.e. similar to rainwater, mineralization status, unlike groundwater. To better understand the origin of mineralization, the data were further analyzed for interrelationships between parameters and for mineral-water relationships using speciation calculations. This provided various tenuous lines of evidence for speculating various modes of groundwater mineralization. Hydrochemical evaluation of major ions suggested an early stage of mineralization which could be attributed to mineral breakdown driven by pH in the vadose zone under the leaching action of H+. Conceivably the soil in recharge areas supplies CO2 to infiltrating rainwater, thus adding to the amount of aqueous CO2 (H2CO3) already entrapped from the atmosphere. Then, H+ ions, produced from the dissociation of aqueous CO2 ( ), reacts along groundwater flow paths with the carbonaceous-sulfated and silicated minerals, resulting in the observed major ion chemistry. The spatial variations in the groundwater chemistry indicated that the type of bedrock aquifer has an effect on the water chemistry.

关键词： Senegal Dindefello Groundwater Mineralization Springwater Hydrogeochemical Evolution Chemical Weathering

Feasibility Analysis of MERIS as a Tool for Monitoring Lake Guiers (Senegal) Water Quality

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Journal of Water Resource and Protection 2016年第1期8卷 100-119页

作者： Seybatou diop Souléye Wade Moshood N. Tijani Institute of Earth Sciences Faculty of Sciences and Techniques Cheikh Anta Diop University of Dakar Dakar Senegal Department of Geology University of Ibadan Ibadan Nigeria

ENVISAT/MERIS scenes of Lake Guiers covering the period 2003-2010 were processed for concentration retrieval of chlorophyll a (CHLa), suspended particulate matter (SPM) and colored fraction of dissolved organic matter (CDOM), i.e. the three main parameters relevant to the water quality management of the lake. Estimates in the range of 30 - 117 μg CHLa L-1 (average 62.13 μg·L-1), 0.10 - 29.0 mg SPM L-1 (average 22.01 mg·L-1), and 1.10 - 1.90 CDOM m-1 (average 1.33 m-1) were recorded, suggesting the possibility of occasional poor quality waters in some compartments of the lake. The values calculated as part of this study are consistent with literature data. On the basis of these estimates, interpretations were made as to the feasibility of applying MERIS data for synoptic environmental monitoring purposes. The data were subjected to statistical analysis, including regression analysis and significance tests. Estimates of CHLa and CDOM revealed some level of correlation, which suggests that phytoplankton biomass degradation may account for nearly 47% of the dissolved optical compounds CDOM. Notable areas of high CHLa and CDOM concentrations are found in the southern inshore zone, an environment with less water agitation. In contrast, SPM concentrations tend to increase in environments of very shallow water marked by high water turbulence and bottom mobility. However, it was not possible to fully assess the model performance and detection accuracy of the results due to lack of ground truths. Nonetheless, the results show concentrations that compared well with the insitu data from earlier studies and data reported elsewhere from other lacustrine systems. Therefore, it can be inferred from this study that MERIS data present a useful low-cost (i.e. cost effective and readily available) approach for environmental monitoring of Lake Guiers waters with excellent spatial coverage. In addition, the study highlight

关键词： Lake Guiers MERIS Environmental Monitoring Water Quality Chlorophyll a Suspended Particulate Matter Colored Dissolved Organic Matter