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Mapping global research trends: Nutrition associations with nonalcoholic fatty liver disease - a Scopus bibliometric analysis

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World Journal of Gastroenterology 2024年第24期30卷 3106-3119页

作者： Muna Shakhshir Sa'ed H Zyoud Department of Nutrition An-Najah National University HospitalNablus 44839Palestine Department of Public Health College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine Department of Clinical and Community Pharmacy College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine Poison Control and Drug information Center College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine Clinical Research Center An-Najah National University HospitalNablus 44839Palestine

BACKGROUND Several bibliometric analyses have been carried out to identify research hotspots and trends in nonalcoholic fatty liver disease(NAFLD)***,there are still significant knowledge gaps that must be filled to advance our understanding of and ability to treat *** To evaluate,through bibliometric and visual analysis,the current status of related research,related research frontiers,and the developmental trends in the field of diet and *** We retrieved publications about diet and NAFLD published between 1987 and 2022 from ***,we used VOSviewer 1.6.20 to perform bibliometric analysis and *** We found a total of 1905 studies,including 1637(85.93%)original articles and 195(10.24%)reviews,focused on the examination of NAFLD and its correlation with diet that were published between 1987 and *** the remaining five types of documents,38 were letters,notes,editorials,meeting minutes,or brief surveys,representing 1.99%of the total *** countries with the most publications on this topic were China(n=539;28.29%),followed by the United States(n=379;19.90%),Japan(n=133;6.98%),and South Korea(n=127;6.6%).According to the citation analysis,the retrieved papers were cited an average of 32.3 times and had an h-index of 106,with 61014 total *** two main clusters on the map included those related to:(1)inflammation and oxidative stress;and(2)Dietary interventions for *** This was the first study to use data taken from Scopus to visualize network mapping in a novel bibliometric analysis of studies focused on diet and *** 2017,the two domains that received the most attention were“dietary interventions for NAFL”’and“‘inflammation and oxidative stress implicated in NAFLD and its correlation with diet.”We believe that this study provides important information for academics,dietitians,and doctors,and that additional research on dietary interventions and NAFLD is warranted.

关键词： Dietary Nutrition Bibliometric Nonalcoholic fatty liver Scopus VOSviewer

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Perspectives for delivery of therapeutics by extravasation of biodegradable microspheres in the brain

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Neural Regeneration Research 2024年第5期19卷 969-970页

作者： Anne-Eva van der Wijk ed VanBavel Amsterdam UMC location University of Amsterdam Department of Biomedical Engineering and PhysicsAmsterdamThe Netherlands Amsterdam Neuroscience Neurovascular Disorders ProgramAmsterdamThe Netherlands Amsterdam Cardiovascular Sciences Microcirculation ProgramAmsterdamThe Netherlands

Development of therapeutics for brain diseases has remained challenging,in particular due to the difficulty of passing the blood-brain *** a result,the current arsenal of therapeutics targeting the brain is limited to small,lipid-soluble drugs and there is a lack of options for treating neuroblastomas,Alzheimer’s disease,and many other devastating *** the advances in strategies for crossing the blood-brain barrier such as the use of nanoparticles(Hersh et al.,2022;Duan et al.,2023),such delivery systems have not yet reached clinical ***,novel platforms for the transport of therapeutics across the blood-brain barrier remain highly *** specifically holds for large molecules such as monoclonal antibodies and recombinant proteins,as well as nucleotide-based therapeutics and cell *** efforts in this field are increasing exponentially,with thousands of publications in the last few years.

关键词： therapeutics holds spite

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Alt isoenzymes Highly Expressed in Fatty Liver, Regulated by Wy-14643 and Free Fatty Acids Treatment, and increases Glyceroneogenesis

Alt Isoenzymes Highly Expressed in Fatty Liver, Regulated by...

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作者： SA’ed ANEES SAMOUR WORAiKAT 重庆医科大学

学位级别：硕士

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A Multilayer Perceptron Artificial Neural Network Study of Fatal Road Traffic Crashes

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Journal of Data Analysis and information Processing 2024年第3期12卷 419-431页

作者： ed Pearson iii Aschalew Kassu Louisa Tembo Oluwatodimu Adegoke Department of Electrical Engineering & Computer Science Alabama A&M University Normal AL USA Department of Mechanical Civil Engineering & Construction Management Alabama A&M University Normal AL USA Department of Mathematics and Computer Science Alabama State University Montgomery AL USA

This paper examines the relationship between fatal road traffic accidents and potential predictors using multilayer perceptron artificial neural network (MLANN) models. The initial analysis employed twelve potential predictors, including traffic volume, prevailing weather conditions, roadway characteristics and features, drivers’ age and gender, and number of lanes. Based on the output of the model and the variables’ importance factors, seven significant variables are identified and used for further analysis to improve the performance of models. The model is optimized by systematically changing the parameters, including the number of hidden layers and the activation function of both the hidden and output layers. The performances of the MLANN models are evaluated using the percentage of the achieved accuracy, R-squared, and Sum of Square Error (SSE) functions.

关键词： Artificial Neural Network Multilayer Perceptron Fatal Crash Traffic Safety

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Mapping the global research landscape on nonalcoholic fatty liver disease and insulin resistance:A visualization and bibliometric study

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World Journal of Hepatology 2024年第6期16卷 951-965页

作者： Sa'ed H Zyoud Omar E Hegazi Samer O Alalalmeh Muna Shakhshir Faris Abushamma Shadi Khilfeh Samah W Al-Jabi Department of Clinical and Community Pharmacy College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine Clinical Research Center An-Najah National University HospitalNablus 44839Palestine College of Pharmacy and Health Sciences Ajman UniversityAjman 346United Arab Emirates Department of Nutrition An-Najah National University HospitalNablus 44839Palestine Department of Medicine College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine Department of Urology An-Najah National University HospitalNablus 44839Palestine Department of Gastroenterology Hepatology and EndoscopyAn-Najah National University HospitalNablus 44839Palestine

BACKGROUND Nonalcoholic fatty liver disease(NAFLD)is a liver condition that is prevalent worldwide and associated with significant health risks and economic *** it has been linked to insulin resistance(iR),this study aimed to perform a bibliometric analysis and visually represent the scientific literature on iR and *** To map the research landscape to underscore critical areas of focus,influential studies,and future directions of NAFLD and *** This study conducted a bibliometric analysis of the literature on iR and NAFLD indexed in the SciVerse Scopus database from 1999 to *** search strategy used terms from the literature and medical subject headings,focusing on terms related to iR and *** software was used to visualize research trends,collaborations,and key thematic *** analysis examined publication type,annual research output,contributing countries and institutions,funding agencies,journal impact factors,citation patterns,and highly cited *** This analysis identified 23124 documents on NAFLD,revealing a significant increase in the number of publications between 1999 and *** search retrieved 715 papers on iR and NAFLD,including 573(80.14%)articles and 88(12.31%)*** most productive countries were China(n=134;18.74%),the United States(n=122;17.06%),italy(n=97;13.57%),and Japan(n=41;5.73%).The leading institutions included the Universitàdegli Studi di Torino,italy(n=29;4.06%),and the Consiglio Nazionale delle Ricerche,italy(n=19;2.66%).The top funding agencies were the National institute of Diabetes and Digestive and Kidney Diseases in the United States(n=48;6.71%),and the National Natural Science Foundation of China(n=37;5.17%).The most active journals in this field were Hepatology(27 publications),the Journal of Hepatology(17 publications),and the Journal of Clinical Endocrinology and Metabolism(13 publications).The main research hotspots were“therapeutic approaches for iR and NAFLD”and“inflamma

关键词： Nonalcoholic fatty liver disease insulin resistance Bibliometric Visualization

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Dominance of transposable element‑related satDNAs results in great complexity of“satDNA library”and invokes the extension towards“repetitive DNA library”

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Marine Life Science & Technology 2024年第2期6卷 236-251页

作者： Monika Tunjić‑Cvitanić Daniel García‑Souto Juan J.Pasantes EvaŠatović‑Vukšić Division of Molecular Biology Ruđer BoškovićInstitute10000 ZagrebCroatia Genomes and Disease Centre for Research in Molecular Medicine and Chronic Diseases(CIMUS)Universidade de Santiago de Compostela15706 Santiago de CompostelaSpain Department of Zoology Genetics and Physical AnthropologyUniversidade de Santiago de Compostela15706 Santiago de CompostelaSpain Centro de investigación Mariña Dpto de BioquímicaXenética e InmunoloxíaUniversidade de Vigo36310 VigoSpain

Research on bivalves is fast-growing,including genome-wide analyses and genome *** characteristics qualify oysters as a valuable model to explore repetitive DNA sequences and their genome *** we char-acterize the satellitomes of five species in the family Ostreidae(Crassostrea angulata,***,***,***,Ostrea edulis),revealing a substantial number of satellite DNAs(satDNAs)per genome(ranging between 33 and 61)and peculiarities in the composition of their *** satDNAs were either associated to or derived from transposable elements,displaying a scarcity of transposable element-unrelated satDNAs in these *** to the non-conventional satellitome constitution and dominance of Helitron-associated satDNAs,comparative satellitomics demanded more in-depth analyses than standardly *** analyses(including ***,the first bivalve species with a defined satellitome)revealed that 13 satDNAs occur in all six oyster genomes,with Cg170/Hindiii satDNA being the most abundant in all of *** the“satDNA library model”highlighted the necessity to adjust this term when studying tandem repeat evolution in organisms with such *** repetitive sequences with potential variation in the organizational form and repeat-type affiliation are examined across related species,the introduction of the terms“TE library”and“repetitive DNA library”becomes essential.

关键词： Satellitome Comparative satellitomics Helitron Bivalves “Dark matter of the genome”

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Mesenchymal stem cell secretome: A promising therapeutic strategy for erectile dysfunction?

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Asian Journal of Urology 2024年第3期11卷 391-405页

作者： Ria Margiana Younes Pilehvar Fatkhurrohmah LAmalia Silvia WLestari Supardi Supardi Reny i’tishom Department of Anatomy Faculty of MedicineUniversitas IndonesiaJakartaIndonesia Master’s Programme Biomedical Sciences Faculty of MedicineUniversitas IndonesiaJakartaIndonesia Andrology Program Faculty of MedicineUniversitas AirlanggaSurabayaIndonesia Dr.Soetomo General Academic Hospital SurabayaIndonesia indonesia General Academic Hospital DepokIndonesia Ciptomangunkusumo General Academic Hospital JakartaIndonesia Cellular and Molecular Research Center Cellular and Molecular Medicine Research InstituteUrmia University of Medical ScienceUrmiaIran Dr.Kariadi Hospital SemarangIndonesia Department of Medical Biology Faculty of MedicineUniversitas IndonesiaJakartaIndonesia Department of Biomedical Science Faculty of MedicineUniversitas Airlangga SurabayaIndonesia

Objective:The secretome,comprising bioactive chemicals released by mesenchymal stem cells(MSCs),holds therapeutic promise in regenerative *** review aimed to explore the therapeutic potential of the MSC secretome in regenerative urology,particularly for treating erectile dysfunction(ed),and to provide an overview of preclinical and clinical research on MSCs in ed treatment and subsequently to highlight the rationales,mechanisms,preclinical investigations,and therapeutic potential of the MSC secretome in this ***:The review incorporated an analysis of preclinical and clinical research involving MSCs in the treatment of ***,it delved into the existing knowledge regarding the MSC secretome,exploring its therapeutic *** methods included a comprehensive examination of relevant literature to discern the processes underlying the therapeutic efficacy of the MSC secretome.

关键词： Erectiledysfunction Mesenchymal stem cell Mesenchymal stem cell secretome Mesenchymal stem cell-derived exosome

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Fritz Ackermann:a true and unequalled friend

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Geo-Spatial information Science 2023年第2期26卷 151-152页

作者： ed Mikhail Professor Emeritus&Former Head Geomatics Engineering Purdue UniversityWest LafayetteINUSA

i am certain that several other contributors to this memorial volume have expounded on the many attributes,both professional and personal,of Professor Fritz *** is unquestionable that he was a giant in our field,on whose shoulders current and future practitioners shall stand in order to keep the wheels of progress and advancement moving forward.

关键词： moving Fritz Ackermann

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摇摆中的“摇摆州”与新移民

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环球财经 2024年第5期 122-123页

作者：丰君子艾德·霍尔(ed Hall)(图) 不详

1796年9月17日,美国首位总统乔治·华盛顿在当时的重要报纸《美国广告者日报》向全体美国人民发表了著名的公开告别信。这封公开信又被称为“华盛顿的告别演说”。信中,华盛顿除了谢绝连任总统的提议,还着重表达了自己对党派斗争与分立... 详细信息

1796年9月17日,美国首位总统乔治·华盛顿在当时的重要报纸《美国广告者日报》向全体美国人民发表了著名的公开告别信。这封公开信又被称为“华盛顿的告别演说”。信中,华盛顿除了谢绝连任总统的提议,还着重表达了自己对党派斗争与分立的看法。

关键词：乔治·华盛顿党派斗争公开信摇摆

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Measuring Societal impact is as Complex as ABC

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Journal of Data and information Science 2019年第3期4卷 6-21页

作者： ed Noyons Centre for Science and Technology Studies Leiden University

Purpose: This paper describes an alternative way of assessing journals considering a broader perspective of its impact. The Area-based connectedness(ABC) to society of journals applied here contributes to the assessment of the dissemination task of journals but with more data it may also contribute to the assessment of other ***/methodology/approach: The ABC approach assesses the performance of research actors, in this case journals, considering the characteristics of the research areas in which they are active. Each paper in a journal inherits the characteristics of its area. These areas are defined by a publication-based classification. The characteristics of areas relate to 5 dimensions of connectedness to society(news, policy, industrial R&D, technology and local interest) and are calculated by bibliometric indicators and social media metrics. Findings: in the paper, i illustrate the approach by showing the results for a few journals. They illustrate the diverse profiles that journals may have. We are able to provide a profile for each journal in the Web of Science database. The profiles we present show an appropriate view on the journals’ societal *** limitations: The classification i apply to perform the analyses is a CWTS in house classification based on Web of Science data. As such the application depends on the(updates of) that system. The classification is available at *** implications: The dimensions of connectedness discussed in this paper relate to the dissemination task of journals but further development of this method may provide more options to monitor the tasks/mission of journals. Originality/value: The ABC approach is a unique way to assess performance or impact of research actors considering the characteristics of the areas in which output is published and as such less prone to manipulation or gaming.

关键词： Non-scientific impact of research ABC to society Societal impact Bibliometric mapping Publication-level classification

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