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期待之变:精神分裂症患者家庭的压力考察

社会工作 2024年第2期 101-122,161-163页

作者：师艺萌高万红云南大学民族学与社会学学院昆明650091 云南大学民族学与社会学学院社会工作系昆明650091

精神分裂症患者家庭的压力研究多集中于照顾负担主导的静态压力分析,但该疾病的长期性与复杂性带来了家庭压力的不断变化,因此,基于动态过程视角研究精神分裂症患者家庭的压力十分必要。本研究以14户精神分裂症患者家庭为例,基于精神分... 详细信息

精神分裂症患者家庭的压力研究多集中于照顾负担主导的静态压力分析,但该疾病的长期性与复杂性带来了家庭压力的不断变化,因此,基于动态过程视角研究精神分裂症患者家庭的压力十分必要。本研究以14户精神分裂症患者家庭为例,基于精神分裂症的四阶段模型,开展深度访谈和参与式观察,分析该类家庭的压力阶段性表征与生成机制。研究结果表明,精神分裂症患者家庭的压力主要表现为病源性压力和角色性压力,在不同康复阶段,这两类压力分别或共同处于显性状态,从而影响家庭的压力体验。进一步分析发现,社会文化所形塑的家庭生活期待与疾病所影响的家庭现实情景之间的张力是家庭压力生成机制的关键。家庭有两个核心期待贯穿康复历程始终:摆脱疾病困扰的健康期待和实现“成人”的角色期待。家庭在现实情境中遭遇的期待之变构成了家庭压力的动态变迁。由此,社会工作者在开展精神分裂症患者家庭服务时,可通过家庭期待调整和情景行动增能来协助家庭应对压力,从而激发此类家庭的主体性。

关键词：家庭压力精神分裂社区康复社会工作

基于患者反馈导向的姑息护理在多发性骨肿瘤患者疼痛干预中的应用

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国际护理学杂志 2024年第12期43卷 2211-2215页

作者：史慧鲍珊慧隋丽丽山东大学齐鲁医院骨外二科济南250012

目的探讨基于患者反馈导向的姑息护理在多发性骨肿瘤患者疼痛干预中的应用价值。方法选取2021年1月至2022年12月山东大学齐鲁医院收治的多发性骨肿瘤患者87例为研究对象,采用单双号随机分组法,分为对照组43例(行常规护理)和观察组44例(... 详细信息

目的探讨基于患者反馈导向的姑息护理在多发性骨肿瘤患者疼痛干预中的应用价值。方法选取2021年1月至2022年12月山东大学齐鲁医院收治的多发性骨肿瘤患者87例为研究对象,采用单双号随机分组法,分为对照组43例(行常规护理)和观察组44例(在对照组基础上行基于患者反馈导向的姑息护理)。比较两组的疼痛情况〔数字评分量表(Numerical Rating Scale,NRS)、癌痛爆发次数〕、自我状态及护理依从性、生存质量、护理满意度。结果护理后,观察组的NRS评分、癌痛爆发次数、简明心境量表(Profile of Mode State,POMS)评分相比于对照组显著下降,观察组的自我效能及生活质量评分相比于对照组显著上升,差异均有统计学意义(P<0.05)。结论以患者反馈导向为基础的姑息护理在多发性骨肿瘤中能达到较理想的护理效果,能减轻疼痛症状,提升患者的自我效能、依从性,改善情绪状态,在满足患者需求、给予尊重支持情况下,有效提升生存质量。

关键词：多发性骨肿瘤疼痛反馈导向姑息护理生存质量

Design and Analysis of Energy Absorbent Bioinspired Lattice Structures

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Journal of Bionic Engineering 2023年第4期20卷 1670-1686页

作者： Lucrezia Greco Federica Buccino Zhuo Xu Laura Vergani Filippo berto Mario Guagliano Seyyed Moahmmad Javad Razavi Sara Bagherifard Department of Mechanical Engineering Politecnico di MilanoMilanItaly Department of Mechanical and Industrial Engineering Norwegian University of Science and TechnologyTrondheimNorway Chemical Engineering and Materials Environment Department Sapienza University of RomeRomeItaly

The increasing demand for energy absorbent structures,paired with the need for more efficient use of materials in a wide range of engineering fields,has led to an extensive range of designs in the porous forms of sandwiches,honeycomb,and *** achieve an even better performance,an ingenious solution is to learn how biological structures adjust their configurations to absorb energy without catastrophic *** this study,we have attempted to blend the shape freedom,offered by additive manufacturing techniques,with the biomimetic approach,to propose new lattice structures for energy absorbent *** this aim we have combined multiple bio-inspirational sources for the design of optimized configurations under compressive *** lattice structures are fabricated based on the designed unit cell geometries and studied using experimental and computational *** individual effect of each bio-inspired feature has been evaluated on the energy absorbance performance of the designed *** on the design parameters of the lattices,a tuning between the strength and energy absorption could be obtained,paving the way for transition within a wide range of real-life applicative scenarios.

关键词： Energy absorbance Lattice structures Bio-inspiration Fused deposition modeling Lightweight design

Rb-Sr isotope dating of silicalite from the Dajiangping massive sulfide ore deposit,Guangdong Province

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Chinese Science Bulletin 1997年第23期42卷 1983-1985页

作者： Wang, hi Li, HY Wang, YX Wang, HH Nanjing Univ Dept Earth Sci Nanjing 210093 Peoples R China

THE Dajiangping pyrite ore deposit located in the Yunfu County of Guangdong Province is asuper-large pyrite ore deposit. Its age has not been defined so far because of the absence of fos-sil. This note is to use Rb-Sr isotope dating of silicalite to constrain the age of the ore depositand place special emphasis on its geological significance.

关键词： pyrite ore deposit silicalite Rb-Sr isotope ore-forming age.

On the evaluation of ALD TiO_(2),ZrO_(2) and HfO_(2) coatings on corrosion and cytotoxicity performances

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Journal of Magnesium and Alloys 2021年第5期9卷 1828-1841页

作者： Mirco Peron Susanna Cogo Maria Bjelland Abdulla Bin Afif Anup Dadlani Elisa Greggio Filippo berto Jan Torgersen Department of Industrial and Mechanical Engineering Norwegian University of Science and TechnologyRichard Birkelands vei 2b7034 TrondheimNorway Department of Biology University of PadovaVia Ugo Bassi 58/b35131PadovaItaly

Magnesium alloys have been widely studied as materials for temporary implants,but their use has been limited by their corrosion ***,coatings have been proven to provide an effective *** only little explored in the field,Atomic Layer Deposition(ALD)stands out as a coating technology due to the outstanding film conformality and density ***,we provide first insights into the corrosion behavior and the induced biological response of 100 nm thick ALD TiO_(2),HfO_(2)and ZrO_(2)coatings on AZ31 alloy by means of potentiodynamic polarization curves,electrochemical impedance spectroscopy(EIS),hydrogen evolution and MTS colorimetric assay with L929 *** three coatings improve the corrosion behavior and cytotoxicity of the ***,HfO_(2)coatings were characterized by the highest corrosion resistance and cell viability,slightly higher than those of ZrO_(2)***_(2)was characterized by the lowest corrosion improvements and,though generally considered a biocompatible coating,was found to not meet the demands for cellular applications(it was characterized by grade 3 cytotoxicity after 5 days of culture).These results reveal a strong link between biocompatibility and corrosion resistance and entail the need of taking the latter into consideration in the choice of a biocompatible coating to protect degradable Mg-based alloys.

关键词： Atomic layer deposition(ALD) Coatings Corrosion resistance Cytocompatibility Magnesium

Peri-nuclear antibodies correlate with survival in Greek primary biliary cirrhosis patients

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World Journal of Gastroenterology 2010年第39期16卷 4938-4943页

作者： Ourania Sfakianaki meri Koulentaki Maria Tzardi Elena Tsangaridou Panayotis A Theodoropoulos Elias Castanas Elias A Kouroumalis Liver Research Laboratory Medical SchoolUniversity of Crete Department of Gastroenterology University Hospital of Heraklion Department of Pathology University Hospital of Heraklion Department of Biochemistry Medical SchoolUniversity of Crete Department of Experimental Endocrinology Medical SchoolUniversity of Crete Liver ResearchLaboratory Medical SchoolUniversity of Crete

AIM:To investigate possible associations of anti-nuclear envelope antibody(ANEA)with disease severity and survival in Greek primary biliary cirrhosis(PBC)***:Serum samples were collected at diagnosis from 147 PBC patients(85%female),who were followed-up for a median 89.5 mo(range 1-240).ANEA were detected with indirect immunofluorescence on 1% formaldehyde fixed Hep2 cells,and anti-gp210 antibodies were detected using an enzyme linked immunosorbent *** were correlated with clinical data,histology,and ***:ANEA were detected in 69/147(46.9%) patients and 31/147(21%)were also anti-gp210 *** ANEA positive patients were at a more advanced histological stage(Ⅰ-Ⅱ/Ⅲ-Ⅳ56.5%/43.5% vs 74.4%/25.6%,P=0.005)compared to the ANEA negative *** had a higher antimitochondrial antibodies(AMA)titer(≤1:160/>1:160 50.7%/49.3%vs 71.8%/28.2%,P=0.001)and a lower survival time(91.7 ±50.7 mo vs 101.8±55 mo,P=0.043).Moreover,they had more advanced fibrosis,portal inflammation,interface hepatitis,and proliferation of bile ductules(P =0.008,P=0.008,P=0.019,and P=0.027,respectively).They also died more frequently of hepatic failure and/or hepatocellular carcinoma(P=0.016).ANEA positive,anti-gp210 positive patients had a difference in stage(Ⅰ-Ⅱ/Ⅲ-Ⅳ54.8%/45.2%vs 74.4%/25.6%,P= 0.006),AMA titer(≤1:160/>1:160 51.6%/48.4%vs 71.8%/28.2%,P=0.009),survival(91.1±52.9 mo vs 101.8±55 mo,P=0.009),and Mayo risk score(5.5 ±1.9 vs 5.04±1.3,P=0.04)compared to the ANEA negative *** positive,anti-gp210 negative patients had a difference in AMA titer(≤1:160/>1:160 50%/50%vs 71.8%/28.2%,P=0.002),stage(Ⅰ-Ⅱ/Ⅲ -Ⅳ57.9%/42.1%vs 74.4%/25.6%,P=0.033),fibrosis(P=0.009),portal inflammation(P=0.018),interface hepatitis(P=0.032),and proliferation of bile ductules(P=0.031).Anti-gp210 positive patients had a worse Mayo risk score(5.5±1.9 vs 4.9±1.7,P=0.038)than the anti-gp210 negative ***:The presence of ANEA and anti-gp210 identifies a subgroup of PBC pati

关键词： Primary biliary cirrhosis Antimitochondrial antibodies Antinuclear antibodies Antibodies against nuclear envelope antigens Anti-gp210 antibodies

第30届女篮亚洲杯参赛球队攻防能力对比分析

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体育科技文献通报 2024年第1期32卷 30-33,121页

作者：尹一威石国兴李协吉湖南科技大学体育学院湖南湘潭411201 湖南省长沙市麓山滨江实验学校湖南长沙410000

本文运用数理统计法、文献资料法、录像观察法以及RSR秩和比综合评价法等,对第30届女篮亚洲杯参赛球队的进攻和防守能力进行对比分析,重点对中日女篮的攻防指标进行比较研究。结果表明:日本女篮与中国女篮的攻防分别排名第1、2位,均处于... 详细信息

本文运用数理统计法、文献资料法、录像观察法以及RSR秩和比综合评价法等,对第30届女篮亚洲杯参赛球队的进攻和防守能力进行对比分析,重点对中日女篮的攻防指标进行比较研究。结果表明:日本女篮与中国女篮的攻防分别排名第1、2位,均处于A级别;韩国女篮和澳大利亚女篮同为B级别,攻防RSR值为0.63,新西兰女篮紧随其后排名第5,位于C级别,菲律宾女篮、黎巴嫩女篮、中国台北女篮同属于D级别;中国女篮和日本女篮在3分球命中数上表现出显著差异(P0.8);中国女篮更倾向于内线中近距离进攻,而日本女篮则更多地采取外线投射进攻;中国女篮在篮板球方面更胜一筹;中国女篮存在罚球命中率不高、抢断数偏低、失误偏多等问题。

关键词：中国女篮攻防能力女篮亚洲杯 RSR

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The structure, expression, and multifaceted role of immune-checkpoint protein VISTA as a critical regulator of anti-tumor immunity, autoimmunity, and inflammation

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Cellular & Molecular Immunology 2018年第5期15卷 438-446页

作者： Wenwen Xu TạMinh hiếu Subramaniam Malarkannan Li Wang Department of Microbiology and Immunology MilwaukeeWI 53226USA Department of Medicine MilwaukeeWI 53226USA Department of Pediatrics Medical College of WisconsinMilwaukeeWI 53226USA Blood Research Institute MilwaukeeWI 53226USA

Among various immunoregulatory molecules,the B7 family of immune-checkpoint receptors consists of highly valuable targets for cancer *** targeting two B7 family co-inhibitory receptors,CTLA-4 and PD-1,have elicited long-term clinical outcomes in previously refractory cancer types and are considered a breakthrough in cancer *** the success,the relatively low response rate(20–30%)warrants efforts to identify and overcome additional immune-suppressive *** the expanding list of T cell inhibitory regulators,V domain immunoglobulin suppressor of T cell activation(VISTA)is a unique B7 family checkpoint that regulates a broad spectrum of immune ***,we summarize recent advances that highlight the structure,expression,and multi-faceted immunomodulatory mechanisms of VISTA in the context of autoimmunity,inflammation,and anti-tumor immunity.

关键词： cancer immunotherapy immune checkpoint autoimmunity inflammation tumor immunity

NEUROCOMPUTING THEORY AND NUmeriCAL SIMULATION ON ELASTICITY

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Acta Mechanica Solida Sinica 1999年第3期12卷 269-278页

作者： Sun, DH Sun, XF hi, Q Xu, H Xiamen Univ Dept Electromech Engn Xiamen 361005 Peoples R China Sw Jiaotong Univ Dept Appl Mech & Engn Chengdu 610031 Peoples R China NE Univ Technol Inst Engn Mech Shenyang 110006 Peoples R China

A new finite element analysis principle based on neural networks is proposed. It can realize the finite element analysis in real time. The neural computation of a simple structure was simulated on digital computer, the effect of input parameters on convergent speed and precision was analyzed. Before solving a certain FE problem, the linking weight matrix of the neural net, i.e., the global stiffness matrix of the structure analyzed, must be defined. In this paper, a method which uses the BP net to compute the element stiffness matrix in real time is proposed.

关键词： neural networks elasticity finite element real-time computation