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Editorial for Multiscale&Multifield coupling in Geomechanics

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第6期16卷 1919-1921页

作者： Min Wang Pengzhi Pan Andrew h.c.chan Y.t.Feng t-3 Fluid Dynamics and Solid Mechanics Theoretical DivisionLos Alamos National LaboratoryNew MexicoUSA Institute of Rock and Soil Mechanics Chinese Academy of SciencesWuhanChina School of Engineering University of TasmaniaTasmaniaAustralia college of Engineering Swansea UniversityWalesUK

We are delighted to serve as guest editors for this special issue in the Journal of Rock Mechanics and Geotechnical *** purpose of this special issue is dedicated to gathering the latest resea.c. work on Multiscale&Multifield coupling in Geomechanics,where we delve into the intricate interplay of various fields and scales that govern the behavior of *** total,30 manuscripts from USa.c.ina,UK,Germany,canada,India and United Arab Emirates are selected to be included in this issue.

关键词： materials. gathering mechanics

RARRES2's impact on lipid metabolism in triplenegative breast ca.c.r:a pathway to brain metastasis

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Military Medical Resea.c. 2024年第2期11卷 311-312页

作者： Quazi t.h.Shubhra Institute of chemistry University of Silesia in Katowice41‑500 ChorzowPoland Department of Neurosurgery Renmin Hospital of Wuhan UniversityWuhan 430060China

Breast ca.c.r brain metastasis(BcBrM)is a.c.ucial and hard area of resea.c. which guarantees an urgent need to understand the underlying molecular mechanisms.A recent study by Li et al.[1]published in Military Medical Resea.c. investigated the role of retinoic acid receptor responder 2(RARRES2)in regulating lipid metabolism in BcBrM,highlighting the clinical releva.c. of alterations in lipid metabolites,such as phosphatidylcholine(Pc)and triacylglycerols(tAGs),by RARRES2 through the modulation of phosphatase and tensin homologue(PtEN)-mammalian target of rapamycin(mtOR)-sterol regulatory element-binding protein 1(SREBP1)signaling *** commentary aims to elaborate on the key findings and their releva.c. to the field.

关键词： Retinoic acid receptor responder 2(RARRES2) Lipid metabolism ca.c.r PtEN-mtOR-SREBP1 signaling Metabolic reprogramming Brain metastasis

Reviewing 40 years of artificial intelligence applied to power systems-A taxonomic perspective

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Energy and AI 2024年第1期15卷 136-150页

作者： F.heymann h.Quest t.Lopez Ga.c.a.c.Ballif M.Galus Swiss Federal Office for Energy(SFOE) Section Geoinformation and Digital InnovationIttigenSwitzerland Ecole Polytechnique Fédérale de Lausanne(EPFL) Photovoltaics and Thin-Film Electronics Laboratory(PV-LAB)Institute of Electrical and Micro Engineering(IEM)NeuchâtelSwitzerland 3S Swiss Solar Solutions AG ThunSwitzerland Swiss center for Electronics and Microtechnology(cSEM) Sustainable Energy CenterNeuchâtelSwitzerland Digital Energy and Electric Power Lucerne University of Applied Sciences and ArtsLucerneSwitzerland

Artificial intelligence(AI)as a multi-purpose technology is gaining increased attention and is now widely used across all sectors of the *** growing complexity of planning and operating power systems makes AI extremely valuable for the power *** now,there has been a lack of clarity regarding the specific points along the power system supply chain where AI applications demonstrate significant value,as well as which AI domains are best suited for such *** study employs an AI taxonomy and automated web sea.c. to qualitatively and quantitatively unveil the biggest potentials of AI in the power *** analysis,based on a review of 258’919 publications between 1982 and 2022,reveals where AI applications are particularly *** consider six AI domains(reasoning,planning,learning,communication,perception,integration&interaction)and 19 use cases from the power supply chain(i.e.,generation,transmission networks,distribution networks,isolated grids/microgrids,market operations and retail).Our findings indicate that,as of now,the focus is predominantly on AI applications in power retail(55%),transmission(14%)and generation(13%).Most analyzed works describe applications built on algorithms of the AI domains“learning”(45%)and“planning”(14%).Results also suggest that the current definition of AI domains is ambiguous,and they highlight missing information on the actual use and successful implementation of AI in power system use cases.

关键词： Artificial intelligence Power systems Electricity taxonomy Policy

Effects of layer interactions on instantaneous stability of finite Stokes flows

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Applied Mathematics and Mechanics(English Edition) 2024年第1期45卷 69-84页

作者： chen ZhAO Zhenli chEN c.t.MUtASA Dong LI School of Aeronautics Northwestern Polytechnical UniversityXi'an 710072China

the stability analysis of a finite Stokes layer is of practical importa.c. in flow control. In the present work, the instantaneous stability of a finite Stokes layer with layer interactions is studied via a linear stability analysis of the frozen phases of the base flow. the oscillations of two plates can have different velocity amplitudes, initial phases, and frequencies. the effects of the Stokes-layer interactions on the stability when two plates oscillate synchronously are analyzed. the growth rates of two most unstable modes when δ t equal, and δ = δ*/h*, where δ*and h*are the Stokes-layer thickness and the half height of the channel, respectively. however, their vorticities are different. the vorticity of the most unstable mode is symmetric, while the other is asymmetric. the Stokes-layer interactions have a destabilizing effect on the most unstable mode when δ have a stabilizing effect when δ > 0.68. however, the interactions always have a stabilizing effect on the other unstable mode. It is explained that one of the two unstable modes has much higher dissipation than the other one when the Stokes-layer interactions are strong. We also find that the stability of the Stokes layer is closely related to the inflectional points of the base-flow velocity profile. the effects of inconsistent velocity-amplitude, initial phase, and frequency of the oscillations on the stability are analyzed. the energy of the most unstable eigenvector is mainly distributed near the plate of higher velocity amplitude or higher oscillation frequency. the effects of the initial phase difference are complicated because the base-flow velocity is extremely sensitive to the initial phase.

关键词： finite Stokes layer instantaneous stability Stokes-layer interaction asynchronous oscillation

Atomistic Investigation of Shock-Induced Amorphization within Micro-shear Bands in hexagonal close-Packed titanium

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Acta Metallurgica Sinica(English Letters) 2024年第9期37卷 1590-1600页

作者： Z.c.Meng K.G.Wang t.Ali D.Li c.G.Bai D.S.Xu S.J.Li A.h.Feng G.J.cao J.h.Yao Q.B.Fan h.Wang R.Yang Institute of Metal Resea.c. Chinese Academy of SciencesShenyang 110016China School of Materials Science and Engineering University of Science and Technology of ChinaShenyang 110016China Interdisciplinary centre for Additive Manufacturing(IcAM) School of Materials and ChemistryUniversity of Shanghai for Science and TechnologyShanghai 200093China School of Materials Science and Engineering Tongji UniversityShanghai 201804China Key Laboratory for Light-Weight Materials Nanjing Tech UniversityNanjing 210009China National Key Laboratory of Science and technology on Materials Under Shock and Impact School of Materials Science and EngineeringBeijing Institute of TechnologyBeijing 100081China Beijing Institute of technology chongqing Innovation center Chongqing 401135China

the mechanical response of a single crystal titanium sample against(0001)α surface impact was investigated using molecular dynamics ***,non-uniform plastic deformation was observed in the *** high strain rates,amorphization occurred near the edge of the contact region where severe shear strain induced a large number of stacking faults(SFs)and *** contrast,the central part of the contact region underwent less deformation with significantly fewer ***,instead of amorphization by consuming SFs and dislocations,there was a gradual increase in the density of dislocations and SFs during the process of *** local amorphous regions eventually grew into shear bands.

关键词： Shock compression Amorphization Shear band titanium Molecular dynamics

Near resona.c. vibration isolation on a levered-dual response(LEDAR)coulomb-damped system by differential preloads/offsets in linear springs

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Applied Mathematics and Mechanics(English Edition) 2024年第6期45卷 1033-1050页

作者： t.I.tOLUWALOJU c.K.thEIN D.hALIM Department of Mechanical Materials and Manufacturing EngineeringUniversity of Nottingham Ningbo ChinaNingbo 315100Zhejiang ProvinceChina Nottingham Ningbo china Beacons of Excellence Resea.c. and Innovation Institute University of Nottingham Ningbo ChinaNingbo 315048Zhejiang ProvinceChina

the levered-dual response(LEDAR)coulomb-damped system attains near resonant vibration isolation by differential preloads/offsets in linear *** takes the advantages of both the preloads/offsets in linear springs and the guiderail friction for realizing different levels of vibration *** isolation capacities are investigated on the strategies with both the horizontal and vertical guiderails,with the horizontal rail only,and without *** compressive preloads generally result in the consumption of most of the initial excitation energy so as to overcome the potential *** isolation onsets at the frequency ratio of 1∓0.095 on the left-hand side(LhS)and the right-hand side(RhS)of the lever are relative to the load plate *** observed near resonant isolation thus makes the LEDAR system a.c.ndidate for the isolation of the mechanical systems about resona.c. while opening a path for simultaneous harvesterisolation functions and passive functions at extreme frequencies.

关键词： lever ratio coulomb damping preload tension/compression isolation band/depth offset potential

Pre-activated macrophage membrane-encased aggregationinduced emission featuring nanoparticles:a novel possibility for tuberculosis treatment

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Signal transduction and targeted therapy 2024年第7期9卷 2848-2850页

作者： Qiang cai Yihao tian Quazi t.h.Shubhra Department of Neurosurgery Renmin Hospital of Wuhan UniversityWuhanChina Department of human Anatomy and histology and Embryology School of Basic Medical SciencesWuhan UniversityWuhanChina Institute of chemistry University of Silesia in KatowiceSzkolna 9KatowicePoland

In a recent study published in Nature Nanotechnology,Li et *** the synthesis of a novel photosensitizer with unique aggregation-induced emission(AIE)characteristics.1 they microencapsulated this photosensitizer inside engineered nanoparticles(NPs)coated with pre-activated macrophage cell membranes(cMs),an innovative approach marking a significant leap in nanomedicine by offering a pathway to potent tuberculosis(tB)treatments that bypass antibiotic resista.c. with unparalleled precision.

关键词： tuberculosis macrophage aggregation

hI in high Gas-phase Metallicity Dwarf Galaxy WISEA J230615.06+143927.9

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Resea.c. in Astronomy and Astrophysics 2024年第1期24卷 292-299页

作者： Yan Guo c.Sengupta t.c.Scott P.Lagos Y.Luo Purple Mountain Observatory Chinese Academy of SciencesNanjing 210023China School of Astronomy and Space Sciences University of Science and Technology of ChinaHefei 230026China Institute of Astrophysics and Space Sciences(IA Porto) Rua das Estrelas4150-762PortoPortugal

We present resolved Giant Metrewave Radio telescope h I observations of the high gas-phase metallicity dwarf galaxy WISEA J230615.06+143927.9(z = 0.005)(hereafter J2306) and investigate whether it could be a tidal Dwarf Galaxy(tDG) candidate. tDGs are observed to have higher metallicities than normal dwarfs. J2306 has an unusual combination of a blue g-r color of 0.23 mag, irregular optical morphology and high-metallicity(12 +log(O/h) = 8.68 ± 0.14), making it an interesting galaxy to study in more detail. We find J2306 to be an h I rich galaxy with a large extended, unperturbed rotating h I disk. Using our h I data we estimated its dynamical mass and found the galaxy to be dark matter(DM) dominated within its h I radius. the quantity of DM, inferred from its dynamical mass, appears to rule out J2306 as an evolved tDG. A wide area environment sea.c. reveals J2306 to be isolated from any larger galaxies which could have been the source of its high gas metallicity. Additionally, the h I morphology and kinematics of the galaxy show no indication of a recent merger to explain the *** detailed optical spectroscopic observations of J2306 might provide an answer to how a seemingly ordinary irregular dwarf galaxy achieved such a high level of metal enrichment.

关键词： galaxies:abunda.c.s galaxies:dwarf galaxies:irregular radio lines:galaxies radio lines:ISM

Viral and nonviral nanocarriers for in vivo cRISPR-based gene editing

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Nano Resea.c. 2024年第10期17卷 8904-8925页

作者： Zhongyuan Guo Audrey t.Zhu Ronnie h.Fang Liangfang Zhang Aiiso Yufeng Li Family Department of chemical and Nano Engineering University of California San DiegoLa JollaCA 92093USA Division of host-Microbe Systems and therapeutics Department of PediatricsUniversity of California San DiegoLa JollaCA 92093USA

the continued development of clustered regularly interspaced short palindromic repeats(cRISPR)technology has the potential to greatly impact clinical medicine,particularly for disease diagnosis and *** high demand for the in vivo delivery of cRISPR-based therapies,significant challenges *** include rapid degradation by enzymes,inefficient disease site targeting,and the risk of undesired off-target *** platforms,with their tailorable properties,have been engineered to efficiently package cRISPR payloads in various formats,including as plasmid DNA,mRNA,and ribonucleoprotein complexes,for in vivo *** them,recombinant adeno-associated viruses,virus-like particles,and lipid nanoparticles have displayed exceptional *** review will discuss the development of these and other nanocarriers for in vivo cRISPR-based genome editing.

关键词： clustered regularly interspaced short palindromic repeats(cRISPR) in vivo gene editing nanocarriers recombinant adeno-associated viruses(rAAVs) virus-like particle(VLP) lipid nanoparticle(LNP)