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Lens density measurements by two independent psychophysical techniques

Eye and Vision 2016年第1期3卷 188-196页

作者： Anirbaan Mukherjee Richard A.bone Department of Physics Florida International University11200 SW 8th StreetMiami 33199FLUSA

Background:cataract,a leading cause of vision impairment,is due to the lens becoming excessively optically *** in the lens optical density(LOD)could be a useful indicator of incipient nuclear cataract and would necessitate the development of accurate measurement *** sf^(TM) is a heterochromatic flicker photometer for measuring macular pigment optical density(MPOD)under photopic *** the process,it also measures LOD that is needed in the calculation of *** is then converted by the instrument to“lens equivalent age”(LEA).However,varying cone photoreceptor ratios among individuals could affect the LEA *** vision is mediated by rod photoreceptors;therefore,LEA measurement under scotopic conditions potentially provides a reliable standard for assessing other *** study was conducted to test the level of agreement between the LEA data obtained under photopic and scotopic conditions for a sample *** also comment on factors that might contribute to any ***:LEAs were obtained by Mapcat sf for 25 subjects and compared with those obtained under absolute scotopic threshold ***:The mean scotopic LEA for the subjects was 2.7 years higher than the mean photopic LEA,but this difference was not statistically *** by the two methods were reasonably correlated(r 2=0.59,pcant individual differences in LEA by the two methods were found for six of the 25 *** our calculations included a standard long-to medium-wavelength-sensitive cone ratio,we found that different ratios could be found that rendered the differences in LEA insignificant for two of these six *** in pupil diameter during scotopic measurements was considered another potential source of discrepancy between LEAs by the two ***:The absolute threshold technique,with long adaptation times,is probably impractical for routine lens density measurement

关键词： cataract Heterochromatic flicker photometry Lens optical density Absolute threshold Photopic Scotopic

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A geospatial search engine for discovering multi-format geospatial data across the web

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International Journal of Digital Earth 2016年第1期9卷 47-62页

作者： Christopher bone Alan Ager Ken Bunzel Lauren Tierney Department of Geography University of OregonEugeneORUSA USDA Forest Service Western Wildland Environmental Threat CenterPrinevilleORUSA Kingbird Software MoscowIDUSA

The volume of publically available geospatial data on the web is rapidly increasing due to advances in server-based technologies and the ease at which data can now be ***,challenges remain with connecting individuals searching for geospatial data with servers and websites where such data *** objective of this paper is to present a publically available Geospatial Search Engine(GSE)that utilizes a web crawler built on top of the Google search engine in order to search the web for geospatial *** crawler seeding mechanism combines search terms entered by users with predefined keywords that identify geospatial data services.A procedure runs daily to update map server layers and metadata,and to eliminate servers that go *** GSE supports Web Map Services,ArcGIS services,and websites that have geospatial data for *** applied the GSE to search for all available geospatial services under these formats and provide search results including the spatial distribution of all obtained *** enhancements to our GSE and to web crawler technology in general lie ahead,our work represents an important step toward realizing the potential of a publically accessible tool for discovering the global availability of geospatial data.

关键词： geospatial data web crawler search engine Web Map Service data access

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Seamount chains and hotspot tracks:Superficially similar,deeply different

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Geoscience Frontiers 2023年第6期14卷 307-326页

作者： Edgardo cañón-Tapia División de Ciencias de la Tierra CICESE.Carretera Ensenada-Tijuana#3985Ensenada Baja CaliforniaCP 22860Mexico

Nearly 80%of the seafloor extension has not been covered by high-resolution bathymetry,impeding direct observation of ***,lists of seamount location and height at a global scale have been produced using different *** this work four of such databases(publicly available)are compared with each other to assess their *** identify large differences among databases that could have exerted strong influences on models of seamount production and associated geodynamic *** those differences,it is shown that all databases allow the identification of seamount lines both along the present-day Mid Ocean Ridge(MOR)system and on intraplate ***,those seamount lines do not coincide with the so-called hotspot tracks that commonly were defined by selectively focusing attention on the larger *** of all the databases also shows that distinction based only on seamount size between seamounts produced at Mid-Ocean Ridge(MOR)environments from those associated with mantle-plum fed-hotspot activity has been ***,combined with the fact that most seamount lines defined by the available databases can be traced back to past locations of MOR indicates that most of the present-day intraplate linear arrays of seamounts,which include some large seamounts,were not produced by the action of underlying mantle anomalies envisaged in the form of mantle *** evidence presented here calls for a reassessment of the form in which volcanic and tectonic activities are conceptually related to each other.

关键词： Seamount origin Chains of seamounts Spatial distribution of volcanism Intraplate volcanism Mid Ocean Ridge volcanism

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Comparative performance analysis of stroke correspondence search methods for stroke-order free online multi-stroke character recognition

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Frontiers of Computer Science 2014年第5期8卷 773-784页

作者： Wenjie ca1 Seiichi UCHIDA Hiroaki SAKOE Department of Advanced Information Technology Kyushu University Fukuoka-shi 819-0395 Japan

For stroke-order free online multi-stroke charac- ter recognition, stroke-to-stroke correspondence search be- tween an input pattern and a reference pattern plays an im- portant role to deal with the stroke-order variation. Although various methods of stroke correspondence have been pro- posed, no comparative study for clarifying the relative su- periority of those methods has been done before. In this pa- per, we firstly review the approaches for solving the stroke- order variation problem. Then, five representative methods of stroke correspondence proposed by different groups, includ- ing cube search （CS）, bipartite weighted matching （BWM）, individual correspondence decision （ICD）, stable marriage （SM）, and deviation-expansion model （DE）, are experimen- tally compared, mainly in regard of recognition accuracy and efficiency. The experimental results on an online Kanji char- acter dataset, showed that 99.17%, 99.17%, 96.37%, 98.54%, and 96.59% were attained by CS, BWM, ICD, SM, and DE, respectively as their recognition rates. Extensive discussions are made on their relative superiorities and practicalities.

关键词： cube search bipartite weighted matching indi-vidual correspondence decision stable marriage deviation-expansion model

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Analysis and Modeling of Slope Stability in the Three-Gorges Dam Reservoir (China)——The case of Huangtupo Landslide

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Journal of Mountain Science 2011年第2期8卷 166-175页

作者： R.COJEAN Y.J.ca Centre de Géosciences Mines-ParisTech Paris France Changjiang Institute of Survey Planning Design & Research CWRC Wuhan China

The water level in the Three Gorges Dam reservoir is expected to change between the elevations of 145 m and 175 m, as a function of the flood control implementation and the intensity of the annual flood. As a matter of fact, the hydraulical and mechanical loadings, related to the water level modifications, will result in alterations in the slope stability conditions. The town of Badong (Hubei), of 20 000 inhabitants, is one of the towns which was submerged by the impoundment of the reservoir. As a consequence, the new town of Badong was constructed on a nearby site which appeared to be partly an unstable site. A part of this site corresponds to an old landslide, the Huangtupo landslide, the base of which had to be submerged by the water of the reservoir. The analysis of the Huangtupo landslide, taking into account various events scenarios, drainage and reinforcement measures and monitoring devices, allows to illustrate the general process implemented all along the reservoir in order to mitigate the landslide hazard.

关键词： Three Gorges Dam Landslide Modelling

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Clinical practice guidelines for full-cycle standardized management of bone health in breast cancer patients

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cancer Innovation 2024年第1期3卷 1-28页

作者： Committee of Full-cycle Standardized Management of bone Health in Breast cancer Patients Fei Ma 不详 Department of Medical Oncology National Cancer CenterNational Clinical Research Center for CancerCancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China

bone health management for breast cancer spans the entire cycle of patient care,including the prevention and treatment of bone loss caused by early breast cancer treatment,the adjuvant application of bone-modifying agents to improve prognosis,and the diagnosis and treatment of advanced bone *** good bone health management means formulating appropriate treatment strategies and dealing with adverse drug reactions,and will help to improve patients'quality of life and survival *** Breast cancer Expert Committee of the National cancer Center for Quality Control organized relevant experts to conduct an in-depth discussion on the full-cycle management of breast cancer bone health based on evidence-based medicine,and put forward reasonable suggestions to guide clinicians to better deal with health issues in bone health clinics.

关键词： bone health bone-modifying drugs breast cancer guidelines

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Design of Sliding Mode Control with Disturbance Observers for Inertial Platform

Design of Sliding Mode Control with Disturbance Observers fo...

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第25届中国控制与决策会议

作者： Yue Hu Yuan ca Shifeng Zhang College of Aerospace Science and Engineering National University of Defense and Technology

ISBN: (纸本)9781467355339

In the flight process, the disturbances such as vibrations and frictions affect the stability accuracy of the servo loop of the inertial platform. Besides, the model uncertainties exist due to the couplings of the three subsystem of the inertial platform. This paper presents a sliding mode controller based on a proportional integral （PI） disturbance observer. The state variables and disturbing torque are estimated accurately by the PI observer. Additionally, an integral sliding mode controller is designed. The vibration and stability error are reduced by employing the integral items of the states in designing the sliding mode surface. The simulation results show that the proposed methods can improve the control precision of the servo loop of the platform.

关键词： integral sliding mode control disturbance observer stabilized control of platform

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Achillea biebersteinii extracts suppress angiogenesis and enhance sensitivity to 5-fluorouracil of human colon cancer cells via the PTEN/AKT/mTOR pathway in vitro

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Asian Pacific Journal of Tropical Biomedicine 2020年第11期10卷 505-515页

作者： Mehmet Kadir Erdoğan can Ali Ağca Hakan Aşkın Department of Biology Faculty of Arts and SciencesBingol University12000BingolTurkey Department of Molecular Biology and Genetics Faculty of Arts and SciencesBingol University12000BingolTurkey Department of Molecular Biology and Genetics Faculty of SciencesAtaturk University25000ErzurumTurkey

Objective:To investigate the antiproliferative,anti-angiogenic,and apoptotic effects of extracts of Achillea biebersteinii(ABE)and combined treatments of ABE with 5-fluorouracil(5-FU)on HT-29 ***:The effects of ABE,5-FU,and combined treatments on the viability of HT-29 cells were determined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide *** analysis was used to determine synergism between ABE and *** apoptotic and anti-angiogenic effects were determined by cell death detection and human vascular endothelial growth factor ELISA method,*** and translational expressions of p53,Bax,Bcl-2,p38 MAPK,Akt,PTEN,and m TOR were also evaluated by real-time PCR and Western blotting ***:ABE decreased the viability of HT-29 cells in a dosedependent *** treatment of hexane,chloroform,and methanol extracts of Achillea biebersteinii with 5-FU at IC50 doses decreased the cell viability to 26.0%,19.1%,and 14.9%,respectively(Pcantly downregulated m TOR,Akt,Bcl-2 expression,upregulated p53,Bax,PTEN,p38 MAPK expression,and exhibited anti-angiogenetic ***:Our findings indicate that ABE shows synergism with 5-FU and inhibits the proliferation of HT-29 cells by inducing apoptosis and suppressing angiogenesis,which may provide biological evidence for further use of ABE in the treatment of colorectal cancer.

关键词： angiogenesis doses colon

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POLES OF ZETA FUNCTIONS OF COMPLETE INTERSECTIONS

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Chinese Annals of Mathematics,Series B 2000年第2期21卷 187-200页

作者： WAN DAQING(Department of Mathematics, University of california, Irvine, ca 92697-3875, USA.) Department of Mathematics University of California Irvine CA 92697-3875 USA

A vanishing theorem is proved for e-adic cohomology with compact support on an affine (singular) complete intersection. As an application, it is shown that for an affine complete intersection defined over a finite field of q elements, the reciprocal "poles" of the zeta function are always divisible by q as algebraic integers. A p-adic proof is also given, which leads to further q-divisibiliy of the poles or equivalently an improvement of the polar part of the AxKatz theorem for an affine complete intersection. Similar results hold for a projective complete intersection.

关键词： Pole Zeta function Complete intersection

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Optimization of phenol degradation by candida tropicalis Z-04 using Plackett-Burman design and response surface methodology

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Journal of Environmental Sciences 2011年第1期23卷 22-30页

作者： Jiangya Zhou Xiaojuan Yu Cong Ding Zhiping Wang Qianqian Zhou Hao Pao Weimin ca School of Environmental Science and Engineering Shanghai Jiaotong University Dongchuan Road 800 Shanghai 200240 China.

Statistical experimental designs were used to optimize the process of phenol degradation by candida tropicalis Z-04, isolated from phenol-degrading aerobic granules. The most important factors influencing phenol degradation （p 〈 0.05）, as identified by a two-level Plackett-Burman design with 11 variables, were yeast extract, phenol, inoculum size, and temperature. Steepest ascent method was undertaken to determine the optimal regions of these four significant factors. Central composite design （CCD） and response surface analysis were adopted to further investigate the mutual interactions between these variables and to identify their optimal values that would generate maximum phenol degradation. The analysis results indicated that interactions between yeast extract and temperature, phenol and temperature, inocuhim size and temperature affected the response variable （phenol degradation） significantly. The predicted results showed that the maximum removal efficiency of phenol （99.10%） could be obtained under the optimum conditions of yeast extract 0.41 g/L, phenol 1.03 g/L, inoculum size 1.43% （V/V） and temperature 30.04℃. These predicted values were further verified by validation experiments. The excellent correlation between predicted and experimental values confirmed the validity and practicability of this statistical optimum strategy. This study indicated the excellent ability of C. tropicalis Z-04 in degrading high-strength phenol. Optimal conditions obtained in this experiment laid a solid foundation for further use of this microorganism in the treatment of highstrength phenol effluents.

关键词： phenol degradation candida tropicalis Z-04 optimization Plackett-Burman design response surface methodology

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