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a.va.ces in the trea.ment of a.tism spectrum disorder:Wha.ton jelly mesenchyma. stem cell tra.spla.ta.ion

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World Journa. of Methodology 2025年第1期15卷 72-79页

作者： Serda. Ka.a.a. ErdinçCivelek Eyüp Ca. Sa.runlu Umut Ka.a.sla. Özlem yıldız Erda. Ka.a.z Depa.tment of Neurosurgery University of Health Sciences TurkeyGaziosmanpaşa Training and Research HospitalIstanbul 34255Türkiye Depa.tment of Pedia.ric a.lergy-Immunology Institute of Health Sciences Marmara UniversityIstanbul 34865Türkiye Center for Stem Cell&Gene Thera.y Resea.ch a.d Pra.tice University of Health Sciences TurkeyIstanbul 34255Türkiye Depa.tment of Child a.d a.olescent Psychia.ry University of Health SciencesGaziosmanpaşa Training and Research HospitalIstanbul 34255Türkiye Depa.tment of Child a.d a.olescent Psychia.ry Kocaeli University Faculty of MedicineKocaeli 41001Türkiye Center for Regenera.ive Medicine a.d Stem Cell Resea.ch&Ma.ufa.turing Liv HospitalIstanbul 34340Türkiye Depa.tment of Histology a.d Embryology Istinye UniversityFaculty of MedicineIstanbul 34010Türkiye Center for Stem Cell a.d Tissue Engineering Resea.ch a.d Pra.tice Istinye UniversityIstanbul 34340Türkiye

Ba.KGROUND a.tism spectrum disorder(a.D)is a.complex neurodevelopmenta. disorder with multifa.eted *** recent studies,neuroinfla.ma.ion a.d immune dysregula.ion ha.e come to the forefront in its *** a.e studies suggesting tha. stem cell thera.y ma. be effective in the trea.ment of *** To evolve the la.dsca.e of a.D trea.ment,focusing on the potentia. benefits a.d sa.ety of stem cell *** a.deta.led ca.e report is presented,displa.ing the positive outcomes observed in a.child who underwent intra.heca. a.d intra.enous Wha.ton’s jelly-derived mesenchyma. stem cells(WJ-MSCs)tra.spla.ta.ion combined with *** The study demonstra.es a.significa.t improvement in the child’s functiona. outcomes(Childhood a.tism Ra.ing Sca.e,Denver 2 Developmenta. Screening Test),especia.ly in la.gua.e a.d gross motor *** serious side effects were encountered during the 2-yea. *** The findings support the sa.ety a.d effectiveness of WJ-MSC tra.spla.ta.ion in ma.a.ing a.D.

关键词： a.tism spectrum disorder Neuroreha.ilita.ion Stem cell tra.spla.ta.ion Wha.ton jelly mesenchyma. stem cells Infla.ma.ion

Grids of stella. models including second ha.monic a.d colors:sola. composition(z = 0.0172,X = 0.7024)

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Resea.ch in a.tronomy a.d a.trophysics 2015年第12期15卷 2244-2262页

作者： Mutlu y?ld?z Ege University Department of Astronomy and Space Sciences

Grids of stella. evolution omy/a.trophysics, such a. pla.et hosting a.e required in ma.y fields of a.tron- sta.s, bina.ies, clusters, chemica.ly peculia. sta.s, etc. In this study, a.grid of stella. evolution models with upda.ed ingredients a.d recently determined sola. a.unda.ces is presented. The sola. va.ues for the initia. a.unda.ces of hydrogen, hea.y elements a.d mixing-length pa.a.eter a.e 0.0172, 0.7024 a.d 1.98, respectively. The ma.s step is sma.l enough （0.01 M） tha. interpola.ion for a.given sta. ma.s is not required. The ra.ge of stella. ma.s is 0.74 to 10.00M. We present results in different forms of ta.les for ea.y a.d genera. a.pli- ca.ion. The second stella. ha.monic, required for a.a.ysis of a.sida. motion of eclips- ing bina.ies, is a.so listed. We a.so construct rota.ing models to determine the effect of rota.ion on stella. structure a.d derive fitting formula. for luminosity, ra.ius a.d the second ha.monic a. a.function of rota.iona. pa.a.eter. We a.so compute a.d list colors a.d bolometric corrections of models required for tra.sforma.ion between theo- retica. a.d observa.iona. results. The results a.e tested for the Sun, the Hya.es cluster, the slowly rota.ing chemica.ly peculia. a. sta.s a.d eclipsing bina.ies with a.sida. motion. The theoretica. a.d observa.iona. results a.ong isochrones a.e in good a.ree- ment. The grids a.e a.so a.plica.le to rota.ing sta.s provided tha. equa.oria. velocity is given.

关键词： sta.s: interior -- sta.s: evolution -- bina.ies: eclipsing -- sta.s: chemi-ca.ly peculia.

On power series sta.istica. convergence a.d new uniform integra.ility of double sequences

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a.plied Ma.hema.ics(a.Journa. of Chinese Universities) 2024年第3期39卷 519-532页

作者： Sevda.y■ld■z Ka.il Demirci Sinop University Department of MathematicsSinopTurkey

In the present pa.er,we mostly focus on P_(p)^(2)-sta.istica. *** will look into the uniform integra.ility via.the power series method a.d its cha.a.teriza.ions for double ***,the notions of P_(p)^(2)-sta.istica.ly Ca.chy sequence,P_(p)^(2)-sta.istica. boundedness a.d core for double sequences will be described in a.dition to these findings.

关键词： power series methods sta.istica. convergence uniform integra.ility double sequences

Hospita.-a.quired insomnia.sca.e:a.va.idity a.d relia.ility study

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World Journa. of Psychia.ry 2023年第3期13卷 113-125页

作者： Ba.a. Çiftçi Güzel Nur yıldız Özgür yıldız Depa.tment of Funda.enta. of Nursing Atateknokent Atatürk UniversityErzurum 25000Turkey Depa.tment of Dia.ysis MuşAlparaslan UniversityMuş49000Turkey Depa.tment of Nursing MuşAlparslan UniversityMuş49000Turkey

Ba.KGROUND Sleep brea.hing,one of the ba.ic huma. needs,is a.physiologica. need tha. a.fects ca.dia. functions,body tempera.ure,da.ly vita.ity,muscle tone,hormone secretion,blood pressure,a.d ma.y *** the interna.iona. litera.ure,studies reported tha. pa.ients ha.e ha. sleep problems in the hospita. since the 1990s,but no mea.urement tool ha. been developed to determine the ca.ses of hospita.a.quired insomnia.in *** findings suggest tha. sleep rema.ns in the ba.kground compa.ed to a.tivities such a. nutrition a.d *** pa.ients genera.ly experience hospita.-a.quired sleep problems,there is no mea.urement tool to determine hospita.-a.quired sleep *** fea.ures show the origina.ity of the *** To develop a.mea.urement tool to determine the sleep problems experienced by pa.ients in the *** a.persona. informa.ion form,hospita.-a.quired insomnia.sca.e(Ha.S),a.d insomnia.severity index(ISI)were used to collect resea.ch *** study popula.ion consisted of pa.ients hospita.ized in the interna. a.d surgica. clinics of a.resea.ch hospita. in Turkey between December 2021 a.d Ma.ch *** sa.ple consisted of 64 pa.ients in the pilot a.plica.ion sta.e a.d 223 pa.ients in the ma.n a.plica.ion *** fa.tor a.a.ysis a.d confirma.ory fa.tor a.a.ysis(CFa.a.a.yses were performed using the SPSS 20 pa.ka.e progra. a.d the a.a.ysis of moment structure(a.OS)pa.ka.e *** forms method *** The Ha.S consisted of 18 items a.d 5 *** Cronba.h a.pha.va.ues of the subsca.es ra.ged between 0.672 a.d 0.842 a.d the Cronba.h a.pha.va.ue of the overa.l sca.e wa. *** sca.e expla.ned 58.269%of the tota. *** items tha. constitute the fa.tors were exa.ined in terms of content integrity a.d na.ed a. physica. environmenta.,psychologica.,sa.ety,socioeconomic,a.d nutritiona. *** a.a.ysis of the 5-fa.tor structure wa. performed in the a.OS pa.ka.e *** fit indices of the

关键词： Insomnia Sleeplessness Sleep disorder Sca.e development Hospita. Hospita. housekeeping

Ta.geting epigenetic mecha.isms in a.yloid-β-media.ed a.zheimer’s pa.hophysiology:unveiling thera.eutic potentia.

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Neura. Regenera.ion Resea.ch 2025年第1期20卷 54-66页

作者： Jennie z.Li Na.endra. Ra.a.inga. Sha.min Li a.n Romney Center for Neurologic Disea.es Brigham and Women’s Hospital and Harvard Medical SchoolBostonMAUSA

a.zheimer’s disea.e is a.prominent chronic neurodegenera.ive condition cha.a.terized by a.gra.ua. decline in memory lea.ing to *** evidence suggests tha. a.zheimer’s disea.e is a.socia.ed with a.cumula.ing va.ious a.yloid-βoligomers in the bra.n,influenced by complex genetic a.d environmenta. *** memory a.d cognitive deficits observed during the prodroma. a.d mild cognitive impa.rment pha.es of a.zheimer’s disea.e a.e believed to prima.ily result from syna.tic *** life,environmenta. fa.tors ca. lea. to enduring cha.ges in gene expression a.d the emergence of bra.n *** cha.ges,known a. epigenetic modifica.ions,a.so pla. a.crucia. role in regula.ing the forma.ion of syna.ses a.d their a.a.ta.ility in response to neurona. *** this context,we highlight recent a.va.ces in understa.ding the roles pla.ed by key components of the epigenetic ma.hinery,specifica.ly DNa.methyla.ion,histone modifica.ion,a.d microRNa.,in the development of a.zheimer’s disea.e,syna.tic function,a.d a.tivity-dependent syna.tic ***,we explore va.ious stra.egies,including enriched environments,exposure to non-inva.ive bra.n stimula.ion,a.d the use of pha.ma.ologica. a.ents,a.med a. improving syna.tic function a.d enha.cing long-term potentia.ion,a.process integra. to epigenetic ***,we delibera.e on the development of effective epigenetic a.ents a.d sa.e thera.eutic a.proa.hes for ma.a.ing a.zheimer’s *** suggest tha. a.dressing a.zheimer’s disea.e ma. require distinct ta.lored epigenetic drugs ta.geting different disea.e sta.es or pa.hwa.s ra.her tha. relying on a.single drug.

关键词： a.zheimer’s disea.e DNa.methyla.ion enriched environments histone modifica.ion microRNa. non-inva.ive bra.n stimula.ion syna.tic pla.ticity

Influence of nickel a.dition on the microstructure a.d mecha.ica. properties of a.2O3–5vol%zrO2 cera.ic composites prepa.ed via.precipita.ion method

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Interna.iona. Journa. of Minera.s,Meta.lurgy a.d Ma.eria.s 2019年第7期26卷 908-914页

作者： Betül Ka.ka.l?o?lu y?ld?z Hüseyin y?lma. ya.ya.Kema. Tür Depa.tment of Ma.eria.s Science a.d Engineering Gebze Technical University

The a.m of this work wa. to investiga.e the microstructure a.d mecha.ica. properties of 1vol%-Ni-a.ded yttria.sta.ilized zirconia.(ySz) toughened a.umina.composites. First, Ni powders were heterogeneously precipita.ed in a. a.umina.zirconia.powder mixture suspended in wa.er;the prepa.ed specimens were then pressureless sintered a. 1550°C/2 h in a.90vol%a./10vol% H2 a.mosphere. The structure of pha.es a.d microstructure of the composites were cha.a.terized by X-ra. diffra.tion a.d sca.ning electron microscopy, respectively. Mecha.ica. cha.a.teriza.ion of the specimens wa. ca.ried out through Vickers ha.dness, Vickers indenta.ion toughness, a.d three-point flexura. bending tests. The fine Ni pa.ticles were homogeneously dispersed throughout the a.umina.ma.rix beca.se of the employed processing method. Furthermore, ha.dness a.d toughness va.ues were found to increa.e by 8% a.d 50%, respectively, with Ni a.dition, wherea. the rela.ive densities a.d flexura. strength va.ues were found to rema.n uncha.ged.

关键词： a.umina zirconia cera.ic ma.rix microstructure ha.dness strength toughness

Bell Polynomia. a.proa.h for the Solutions of Fredholm Integro- Differentia. Equa.ions with Va.ia.le Coefficients

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Computer Modeling in Engineering & Sciences 2020年第6期123卷 973-993页

作者： Gökçe yıldız Gültekin Tına.tepe Mehmet Sezer Depa.tment of Ma.hema.ics Faculty of ScienceManisa Celal Bayar UniversityManisaTurkey Voca.iona. School of Technica. Sciences Akdeniz UniversityAntalyaTurkey

In this a.ticle,we a.proxima.e the solution of high order linea. Fredholm integro-differentia. equa.ions with a.va.ia.le coefficient under the initia.-bounda.y conditions by Bell *** colloca.ion points a.d trea.ing the solution a. a.linea. combina.ion of Bell polynomia.s,the problem is reduced to linea. system of equa.ions whose unknown va.ia.les a.e Bell *** solution to this a.gebra.c system determines the a.proxima.e *** estima.ion of a.proxima.e solution is *** exa.ples a.e provided to illustra.e the performa.ce of the *** numerica. results a.e compa.ed with the colloca.ion method ba.ed on Legendre polynomia.s a.d the other two methods ba.ed on Ta.lor *** is observed tha. the method is better tha. Legendre colloca.ion method a.d a. a.cura.e a. the methods involving Ta.lor polynomia.s.

关键词： Bell polynomia.s colloca.ion points ma.rix method Fredholm integrodifferentia. equa.ions.

Violence towa.d emergency physicia.s: a.prospective-descriptive study

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World Journa. of Emergency Medicine 2021年第2期12卷 111-116页

作者： Ka.ım Turgut Erda. ya.uz Mine Ka.a.ıyıldız Mehmet Ka.n Poyra. Depa.tment of Emergency Medicine Research and Training HospitalAdiyaman UniversityAdiyaman 02100Turkey

Ba.KGROUND: The highest ra.e of workpla.e violence occurs in the hea.th sector, a.though most ca.es rema.n unreported. Emergency services fa.e the ma.ority of these incidents for ma.y rea.ons, such a. the pa.ient profile, long wa.ting time, a.d overcrowding. We a.med to determine the cha.a.teristics a.d ca.ses of violence towa.d emergency physicia.s. METHODS: The a.ts of violence towa.d emergency physicia.s over a.one-yea. period were prospectively recorded. a.ter a.violent incident took pla.e, a.third pa.ty sepa.a.ely interviewed the physicia. exposed to the violent beha.ior a.d the perpetra.or who displa.ed this beha.ior. We exa.ined the perpetra.or's rea.ons for violence, their demogra.hic cha.a.teristics, a.d the medica. compla.nts of pa.ients involved in such events to determine the cha.a.teristics a.d ca.ses of ***: Of the violent a.ts investiga.ed, 85.1% were verba., a.d most were directed towa.d ma.e doctors by the young ma.e rela.ives of the pa.ients. More tha. ha.f of the violent a.ts occurred within the 15 minutes of presenta.ion to emergency service(60.5%) a.d a. off-hours(69.4%). Concerning the hea.th insura.ce, 20.4% of the ca.es were covered by the free green ca.d system, a.d a.sma.l number of the perpetra.ors of violence lived in rura. a.ea.(38.2%). The most common rea.on for violent beha.ior wa. the pa.ients' or their rela.ives' dissa.isfa.tion with the exa.ina.ion or trea.ment method(38.2%).CONCLUSIONS: a.propria.e communica.ion should be esta.lished with the pa.ients, a.d they should be a.equa.ely informed a.out the trea.ments a.d interventions to be performed in order to prevent possible a.ts of violence.

关键词： Violence Emergency physicia. Emergency depa.tment

On ϕ-( n,N )-idea.s of Commuta.ive Rings

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a.gebra.Colloquium 2023年第3期30卷 481-492页

作者： a.a. a.ebri Na.ib Ma.dou Ünsa. Tekir Eda.yıldız La.ora.ory of Modelling a.d Ma.hema.ica. Structures Department of MathematicsFaculty of Science and Technology of FezBox 2202University S.M.Ben Abdellah FezMorocco Depa.tment of Ma.hema.ics Marmara UniversityIstanbulTurkey Depa.tment of Ma.hema.ics Yildiz Technical University34220IstanbulTurkey

Let R be a.commuta.ive ring with nonzero identity a.d n be a.positive *** this pa.er,we introduce a.d investiga.e a.new subcla.s ofϕ-n-a.sorbing prima.y idea.s,which a.e ca.ledϕ-(n,N)-***ϕ:I(R)→I(R)∪{∅}be a.function,where I(R)denotes the set of a.l idea.s of R.a.proper idea. I of R is ca.led a.-(n,N)-idea. if x1⋯xn+1∈I\ϕ(R)a.d x1⋯xn∉I imply tha. the product of xn+1 with(n−1)of x1,…,xn is in 0–√for a.l x1,…,xn+1∈*** a.dition to giving ma.y properties ofϕ-(n,N)-idea.s,we a.so use the concept ofϕ-(n,N)-idea.s to cha.a.terize rings tha. ha.e only finitely ma.y minima. prime idea.s.

关键词： Φ-(n N)-idea. Φ-n-a.sorbing prima.y idea. Φ-n-a.sorbing idea. Φ-prime