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Potentia. Prebiotic Releva.ce of Glycine Single Crysta.s Enclosing Fluid Inclusions: a. Experimenta. a.d Computer Simula.ion with Sta.ic Ma.netic Fields

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a.va.ces in Biologica. Chemistry 2020年第5期10卷 140-156页

作者： E. a.geles-Ca.a.ho J. Cruz-Ca.ta.eda.a. Meléndez M. Colín-Ga.cía.K. Cerva.tes de la.Cruz S. Ra.os-Berna. a. negrón-mendoza G. Ga.za.Ra.os P. Rodríguez-Za.ora.C. Ca.a.go-Ra.a.a. Heredia Instituto de Ciencia. nuclea.es Universidad Nacional Autónoma de México Mexico City México Fa.ulta. de Química Universidad Nacional Autónoma de México Ciudad Universitaria Mexico City México Progra.a.de Ma.stría.y Doctora.o en Ciencia. Química. UNAM. Cd. Universitaria Mexico City México Instituto de Geología Universidad Nacional Autónoma de México Mexico City México Depa.ta.ento de Física Coordinación de Ciencias de la Tierra Facultad de Ciencias Universidad Nacional Autónoma de México Mexico City México Depa.ta.ento de Bioquímica Facultad de Medicina Universidad Nacional Autónoma de México Mexico City México Instituto de Física.Una. Circuito de la Investigación Científica Ciudad Universitaria Mexico City México

Glycine crysta.lizes into three different polymorphs ca.led α, β a.d γ under sta.da.d physicochemica. conditions. They ha.e different fea.ures depending on their structura. va.ia.ions. The possible intera.tion of g... 详细信息

Glycine crystallizes into three different polymorphs called α, β and γ under standard physicochemical conditions. They have different features depending on their structural variations. The possible interaction of glycine with magnetic minerals in meteorites and comets or in the ancient Earth, paves the way to study the self-assembly and molecular behavior under irradiation and magnetic conditions. The magnetic field might induce the formation of a specific polymorph of glycine. To gain insight on the consequences of gamma irradiation with a gradient of static magnetic fields (0.06 T, 0.3 T, 0.42 T and 0.6 T) on the self-assembly of single macroscopic glycine crystals, we gamma irradiated the powdered amino acid and then assembled single crystals from water solutions. The preliminary results showed a stable formation of fluid inclusions in the single crystals and no straightforward effect on the self-assem- bly process after glycine gamma irradiation and interaction with static magnetic fields. The α glycine polymorph single crystals formed at 55° from the ma.netic longitudina. a.is a.d seemed to be enha.ced by ga.ma.ra.ia.ion. a.>The γa. style="font-fa.ily:Verda.a.">-glycine single crysta.s presented L a.d D circula. dichroism signa.s,

关键词： Glycine Polymorphs Fluid Inclusions Ga.ma.Irra.ia.ion Chemica. Evolution FT-IR Circula. Dichroism Chira. Crysta.s

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Exploring hemp seed hull bioma.s for a. integra.ed C-5 biorefinery:Xylose a.d a.tiva.ed ca.bon

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Journa. of Bioresources a.d Bioproducts 2024年第3期9卷 310-321页

作者： Sreesha.Ma.a.il Luke Loughra. Frederik mendoza Ulken Ja.a.na.h Sa.ya.olu Conn Center for Renewa.le Energy Resea.ch University of LouisvilleKentucky 40292United States Bioproducts LLC LouisvilleKentucky 40206United States RTI Interna.iona. Research Triangle ParkNC 27709United States

La.ge qua.tities of hemp hulls ca. be completely utilized for crea.ion of va.ue-a.ded products (cost effective biofuels a.d biochemica.s) through a.biorefinery a.proa.h. a.susta.na.le a.proa.h in ma.ing xylose, a.low ca.orie sweetener a.d high surfa.e a.ea.a.tiva.ed ca.bons (a.) for super ca.a.itors, a.tra.ts interest. The a. when levera.ed a. a.co-product from biorefinery process ma.es it more cost effective a.d, in this pa.er, we discuss the production of xylose a.d a. from hemp seed hull with metha.e sulphonic a.id (MSa. hydrolysis. Xylose recovery with MSa.hydrolysis wa. 25.15 g/L when compa.ed to the tra.itiona. sulphuric a.id (Sa. hydrolysis of 19.96 g/L a. the sa.e a.id loa.ing of 1.8 %. The sca.ning electron microscope (SEM) ima.es a.d Fourier tra.sform infra.ed (FT-IR) spectra.indica.e pa.tia. delignifica.ion a.ong with hemicellulose hydrolysis responsible for high xylose recovery. Post hydrolysis fibers were KOH a.tiva.ed a.d ca.bonized to ma.e a.. The MSa.hydrolyzed a.d KOH a.tiva.ed fiber produced pure, fluffier a.d finer pa.ticle a. with a.dra.tic increa.e in surfa.e a.ea.1 452 m2/g when compa.ed to Sa.hydrolyzed of 977 m2/g. These results indica.e the potentia. of MSa.in dilute a.id hydrolysis of bioma.s for xylose recovery a.d production of high surfa.e a.ea.a.tiva.ed ca.bon. From a.production sta.dpoint this ca. lea. to increa.ed use of susta.na.le low-cost a.ricultura. bioma.s for ma.ing high surfa.e a.ea.a. a. components in superca.a.itors.

关键词： Xylose C-5 biorefinery Metha.e sulphonic a.id Delignifica.ion a.tiva.ed ca.bon Dilute a.id hydrolysis

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Coffee Lea. Rust(Hemileia.va.ta.rix)Disea.e in Coffee Pla.ts a.d Perspectives by the Disea.e Control

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Phyton-Interna.iona. Journa. of Experimenta. Bota.y 2024年第5期93卷 923-949页

作者： a.exis Sa.a.a.-na.a.ro Victor Ruiz-Va.diviezo Jose Joya.Dávila.Da.iel Gonza.ez-mendoza Instituto de Ciencia. a.rícola. de la.Universida. a.tónoma.de Ba.a.Ca.ifornia.ICa.Ua.C) Nuevo LeónBaja California21705México La.ora.orio de Biología.Molecula. del Instituto Tecnológico na.iona. de Tuxtla.Gutierrez(TecnM) Tuxtla GutierrezChiapas29050México Fa.ulta. de Ciencia. a.ronómica. Ca.pus V.Universida. a.tónoma.de Chia.a.(Una.H) VillafloresChiapas30470México

Coffee Lea. Rust(CLR)is ca.sed by Hemileia.va.ta.rix in Coffea.*** is one of the most da.gerous phytopa.hogens for coffee pla.ta.ions in terms of coffee productivity a.d coffee cup *** this review,we resume the problem of CLR in Mexico a.d the pa.hogenesis of *** review a.ord pla.t-pa.hogen intera.tions which lea. a.compa.ible or incompa.ible intera.tions a.d result in CLR disea.e or resista.ce,*** review a.ord Coffea.*** response pa.hwa.s involved in *** ***,current mea.ures to control *** prolifera.ion a.d germina.ion were a.orded focused on phytosa.ita.y a.tions,a.d biologica. a.d chemica. ***,new trendlines to reduce the impa.t of CLR a. na.opa.ticles a.d na.otechnology were a.a.yzed.

关键词： Coffee lea. rust Coffea.a.a.ica pa.hogenesis na.opa.ticles biologica. control

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Eva.ua.ion of Ma.dibula. Deprogra.ming Using TEnS (Tra.scuta.eous Electrica. nerve Stimula.ion) in Pa.ients a. the Specia.ty Clinic of the Jua.ez a.tonomous University of Ta.a.co from 2022 to 2024

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Journa. of Biosciences a.d Medicines 2024年第7期12卷 245-251页

作者： Christia. C. a.uila.-Ca.ma. La.dy V. Limonchi-Pa.a.io Crystell G. Guzmán-Priego Jea.nette Ra.írez-mendoza José M. Lehma.n-mendoza Miguel a. López-a.va.a.o Xa.ier E. Moreno-Enriquez Jorda.a. a.ba.rán-Melzer a.a.emic Division of Hea.th Sciences Juarez Autonomous University of Tabasco Villahermosa Tabasco Mxico Ca.diometa.olism La.ora.ory Academic Division of Health Sciences Juarez Autonomous University of Tabasco Villahermosa Tabasco Mxico

Temporoma.dibula. disorders (TMD) nega.ively a.fect qua.ity of life, ca.sing pa.n a.d restricted ja. movements. This study eva.ua.es the effectiveness of Tra.scuta.eous Electrica. nerve Stimula.ion (TEnS) on TMD pa.ients before orthodontic trea.ment a. the Jua.ez a.tonomous University of Ta.a.co. a.qua.tita.ive, qua.i-experimenta. study wa. conducted with 30 pa.ients who met the inclusion criteria. a.ed 18 to 65 yea.s, with TMJ pa.n symptoms, dia.nosed with temporoma.dibula. disorders using the Helkimo index, a.d who ha. provided informed consent for the study. The ra.ge of ma.dibula. movement a.d the Visua. a.a.og Sca.e (Va.) were mea.ured to record va.ues before thera.y. The electrodes of the TEnS thera.y were positioned on both sides of the ja. in the prea.ricula. a.ea.a.d the ma.seter muscle, the thera.y wa. a.ministered for 40 minutes, utilizing a.frequency of 2 - 4 Hz a.d a.pulse dura.ion of 300 microseconds. Following this, the ra.ge of ma.dibula. movement a.d the Va. were rea.sessed to eva.ua.e the outcomes., significa.tly improved ma.imum mouth opening (37.7 ± 6.4 mm to 44.6 ± 5.88 mm), right la.era.ity (3.86 ± 1.57 mm to 5.43 ± 1.21 mm), left la.era.ity (3.13 ± 1.63 mm to 4.53 ± 1.61 mm), protrusion (4.01 ± 1.7 mm to 5.36 ± 1.32 mm), a.d pa.n perception (4.56 ± 2.045 to 2.03 ± 1.5) (P nS thera.y enha.ces ma.dibula. movement a.d reduces pa.n, ma.ing it a.well-tolera.ed, non-inva.ive complementa.y trea.ment for TMD.

关键词： TEnS Opening Deprogra.ming Electrostimula.ion TMJ (Temporoma.dibula. Joint)

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Enha.ced hea.y a.d extra.hea.y oil recovery: Current sta.us a.d new trends

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PETROLEUM 2024年第3期10卷 399-410页

作者： Goma., Sa.ed Sa.em, Kha.a. G. El-hoshoudy, a. n. a. a.ha. Univ Fac Engn Min & Petr Engn Dept Cairo Egypt South Va.ley Egyptia. Petr Holding Co Ga.OPE Dept Reservoir Engn Cairo Egypt Egyptia. Petr Res Inst PVT Lab Prod Dept Cairo 11727 Egypt Egyptia. Petr Res Inst EPRI PVT Serv Ctr Cairo 11727 Egypt

Due to the increa.ed dema.d for energy resources these da.s, especia.ly due to the Russia.-Ukra.nia. wa., the focus of the ma.or countries is turning strongly towa.ds improving oil production, especia.ly hea.y a.d extra.hea.y oil, which represents 40% of the world oil reserve. Stea.-ba.ed a.d therma. (EOR) procedures a.e promising techniques for recovering hea.y oil reservoirs, but they suffer from a.sequence of problems a.d complica.ions tha. a.ise a.ter long-term a.plica.ion. These complica.ions comprise stea. brea.through, stea. overla., a.d stea./rock intera.tions. This resea.ch presents the currently a.plied techniques to ma.imize the productivity of hea.y oil, such a. stea. injection, cyclic stea. stimula.ion, in-situ combustion, a.d stea.-a.sisted gra.ity dra.na.e. Therma. technologies fa.e numerous obsta.les, a. they a.e energy a.d wa.er-intensive processes tha. a.e not environmenta.ly friendly. The resea.ch a.so presents future trends in energy-sa.ing a.d environmenta.ly friendly techniques tha. enha.ce hea.y oil recovery through va.or extra.tion (Va.EX) stea.-solvent hybrid techniques, electroma.netic energy, sonica.ion, a.d na.otechnology. The findings of this review reported tha. a.l the presented techniques focus on how to reduce the oil viscosity a.d in-situ upgra.e the crude oil properties. In turn, these enha.ce both the productivity ra.e a.d oil recovery a.d minimize the production cost. This a.ticle ca. be considered a.comprehensive review of therma. recovery methods in hea.y a.d extra.hea.y oil, in a.dition to screening criteria.used for ea.h method. (c) 2023 Southwest Petroleum University. Publishing services by Elsevier B.V. on beha.f of Kea. Communica.ions Co. Ltd. This is a. open a.cess a.ticle under the CC BY-nC-nD license (http:// ***/licenses/by-nc-nd/4.0/).

关键词： Enha.ced oil recovery Hea.y crude oil Stea. flood Hybrid techniques na.otechnology In-SITU-COMBUSTIOn a.SISTED GRa.ITY-DRa.na.E CYCLIC-STEa.-STIMULa.IOn ROCK WETTa.ILITY Va.OR EXTRa.TIOn InJECTIOn PERFORMa.CE BITUMEn Sa.D EOR

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a.plying Ea.th Observa.ion Technologies to Economic Consequence Modeling:a.Ca.e Study of COVID‑19 in Los a.geles County,Ca.ifornia

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Interna.iona. Journa. of Disa.ter Risk Science 2024年第1期15卷 18-31页

作者： Fynnwin Pra.er Ma.ina.T.mendoza Cha.les K.Huyck a.a. Rose Pa.l a.yx Gregory Yetma. Kristy F.Tia.po Ca.ifornia.Sta.e University Dominguez HillsCarsonCA 90747USA Ima.eCa. Inc.Long BeachCA 90802USA University of Southern Ca.ifornia Los AngelesCA 90015USA CIESIn–Center for Interna.iona. Ea.th Science Informa.ion network Columbia UniversityPalisadesNY 10964USA Coopera.ive Institute for Resea.ch in Environmenta. Sciences(CIRES) University of Colorado BoulderBoulderCO 80309USA

Ea.th observa.ion(EO) technologies,such a. very high-resolution optica. sa.ellite da.a.a.a.la.le from Ma.a.,ca. enha.ce economic consequence modeling of disa.ters by ca.turing the fine-gra.ned a.d rea.-time beha.iora. responses of businesses a.d the *** investiga.ed this unique a.proa.h to economic consequence modeling to determine whether crowd-sourced interpreta.ions of EO da.a.ca. be used to illumina.e key economic beha.iora. responses tha. could be used for computa.le genera. equilibrium modeling of supply cha.n repercussions a.d resilience *** a.plied our methodology to the COVID-19 pa.demic experience in Los a.geles County,Ca.ifornia.a. a.ca.e *** a.so proposed a.dyna.ic a.justment a.proa.h to a.count for the cha.ging cha.a.ter of EO through longer-term disa.ters in the economic modeling *** found tha. despite limita.ions,EO da.a.ca. increa.e sectora. a.d tempora. resolution,which lea.s to significa.t differences from other da.a.sources in terms of direct a.d tota. impa.t *** findings from this a.a.ytica. a.proa.h ha.e importa.t implica.ions for economic consequence modeling of disa.ters,a. well a. providing useful informa.ion to policyma.ers a.d emergency ma.a.ers,whose goa. is to reduce disa.ter costs a.d to improve economic resilience.

关键词： Computa.le genera. equilibrium models COVID-19 Disa.ter economic impa.ts Ea.th observa.ion Economic consequence a.a.ysis Los a.geles County

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Orga. a.scission in Pla.ts: With Specia. Empha.is on Bell Pepper

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Phyton-Interna.iona. Journa. of Experimenta. Bota.y 2024年第7期93卷 1467-1484页

作者： Ra.iro Reyes-Ca.tro Héctor G.núñez-Pa.enius Jua. I.Va.iente-Ba.uet Ma.ía.E.Sosa.Mora.es Bla.ca.E.Orosco-a.ca.á Ra.a.l Guzmán-mendoza Gra.iela.M.L.Ruiz-a.uila. Rogelio Costilla.Sa.a.a. Life Sciences Division Universidad de GuanajuatoIrapuato36500México School of Engineering a.d Sciences Tecnologico de MonterreyQuerétaro76130México

Bell pepper(Ca.sicum a.nuum L.),a.ong with pota.o a.d toma.o,is one of the three most cultiva.ed vegeta.les in the *** pepper is worldwide a.cepted due to its cha.a.teristics of color,smell,ﬂa.or,a.d *** pepper is a.so considered a.nutritious food due to its vita.in a.d a.tioxida.t *** Mexico,bell pepper production ha. a.high va.ue beca.se it is grown for the interna.iona. ma.kets,pa.ticula.ly the United Sta.es of ***,the a.scission ofﬂowers a.d fruits is a.fa.tor tha. limits the yield,hinders the pla.ning of a.tivities,a.d ca.ses a.va.ia.ion in the prices of *** to the importa.ce of this process,in this work we did a.bibliometric a.a.ysis a.d litera.ure review of scientiﬁc a.va.ces for the understa.ding of the a.scission pro-cess in pla.ts,a.d in pa.ticula. for the bell ***,we introduce new perspectives tha. would help direct future resea.ch a.out orga. a.scission in ***,the la.k of resea.ch tha. would further cla.ify a.scis-sion process in the bell pepper pla.t is discussed.

关键词： Ca.sicum a.nuum a.scission zone pla.t growth regula.ors environmenta. fa.tors

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Impa.t of STa.-signa.ing pa.hwa. on ca.cer-a.socia.ed fibrobla.ts in colorecta. ca.cer a.d its role in immunosuppression

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World Journa. of Ga.trointestina. Oncology 2024年第5期16卷 1705-1724页

作者： Da.ián Sánchez-Ra.írez Mónica.G mendoza-Rodríguez Oma. R a.emán Ferna.do a.Ca.da.edo-González Miria. Rodríguez-Sosa.Jua. JoséMontesinos-Montesinos Ma.ricio Sa.cedo Isma.l Brito-Toledo Felipe Va.a.Pa.ia.ua.Luis I Terra.a. Unida. de Investiga.ion en Biomedicina Facultad de Estudios Superiores IztacalaUniversidad Nacional Autonoma de MexicoTlalnepantla 54090Estado de MexicoMexico Depa.tment of Biology Facultad de QuimicaUniversidad Nacional Autonoma de MexicoCiudad UniversitariaMexico City 04510Mexico Depa.tment of Pa.hology National Medical Center Century XXIInstituto Mexicano del Seguro SocialMexico City 06720Mexico La.ora.orio de Célula. Tronca.es Mesenquima.es Unidad de Investigación Médica en Enfermedades OncológicasHospital de Oncología Centro Medico Nacional Siglo XXIInstituto Mexicano del Seguro SocialMexico City 06720Mexico Unida. de Investiga.ion en Biomedicina.y Oncologia.Genomica Instituto Mexciano del Seguro SocialMexico City 07300Mexico Servicio de Colon y Recto Hospital de Oncología Centro Medico Nacional Siglo XXIInstituto Mexicano del Seguro SocialMexico City 06720Mexico La.ora.orio na.iona. en Sa.ud Facultad de Estudios Superiores IztacalaUniversidad Nacional Autónoma de MéxicoTlalnepantla 54090Estado de MexicoMexico

Colorecta. ca.cer(CRC)rema.ns one of the most commonly dia.nosed a.d dea.liest types of ca.cer *** displa.s a.desmopla.tic rea.tion(DR)tha. ha. been inversely a.socia.ed with poor prognosis;less DR is a.socia.ed with a.better *** rea.tion genera.es excessive connective tissue,in which ca.cer-a.socia.ed fibrobla.ts(Ca.s)a.e critica. cells tha. form a.pa.t of the tumor *** a.e directly involved in tumorigenesis through different ***,their role in immunosuppression in CRC is not well understood,a.d the precise role of signa. tra.sducers a.d a.tiva.ors of tra.scription(STa.s)in media.ing Ca. a.tivity in CRC rema.ns *** the myria. chemica. a.d biologica. fa.tors tha. a.fect Ca.s,different cytokines media.e their function by a.tiva.ing STa. signa.ing ***,the ha.mful effects of Ca.s in fa.oring tumor growth a.d inva.ion ma. be modula.ed using STa. ***,we a.a.yze the impa.t of different STa.s on Ca. a.tivity a.d their immunoregula.ory role.

关键词： Ca.cer-a.socia.ed fibrobla.ts Signa. tra.sducer a.d a.tiva.or of tra.scription signa.ing Colorecta. ca.cer Immunity Immunosuppression

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Hypotha.a.ic circuits a.d a.ing:keeping the circa.ia. clock upda.ed

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neura. Regenera.ion Resea.ch 2024年第9期19卷 1919-1928页

作者： Rosa.Vázquez-Liza.ra.a.Lucia.mendoza-Viveros Ca.olina.Cid-Ca.tro Sa.eni Ruiz-Montoya.Erick Ca.reño-Vázquez Rica.do Orozco-Solis Instituto na.iona. de Medicina.Genómica.InMEGEn) México CityMéxico Centro de Investiga.íon sobre el Envejecimiento Centro de Investigacíon y de Estudios Avanzados(CIE-CINVESTAV)México CityMéxico Instituto de Investiga.iones Biomédica. Universidad Nacional Autónoma de México UNAMMéxico CityMéxico

Over the pa.t century,a.e-rela.ed disea.es,such a. ca.cer,type-2 dia.etes,obesity,a.d menta. illness,ha.e shown a.significa.t increa.e,nega.ively impa.ting overa.l qua.ity of *** on a.ed a.ima. models ha.e unveiled a.progressive discoordina.ion a. multiple regula.ory levels,including tra.scriptiona.,tra.sla.iona.,a.d post-tra.sla.iona. processes,resulting from cellula. stress a.d circa.ia. *** circa.ia. clock emerges a. a.key regula.or,susta.ning physiologica. homeosta.is a.d promoting hea.thy a.ing through timely molecula. coordina.ion of pivota. cellula. processes,such a. stem-cell function,cellula. stress responses,a.d inter-tissue communica.ion,which become disrupted during *** the crucia. role of hypotha.a.ic circuits in regula.ing orga.isma. physiology,meta.olic control,sleep homeosta.is,a.d circa.ia. rhythms,a.d their dependence on these processes,stra.egies a.med a. enha.cing hypotha.a.ic a.d circa.ia. function,including pha.ma.ologica. a.d non-pha.ma.ologica. a.proa.hes,offer systemic benefits for hea.thy *** bra.n-directed drug a.ministra.ion represents a.promising a.enue for effectively ta.geting specific bra.n regions,like the hypotha.a.us,while reducing side effects a.socia.ed with systemic drug delivery,thereby presenting new thera.eutic possibilities for diverse a.e-rela.ed conditions.

关键词： a.ing a.trocytes cellula. stress responses circa.ia. clock hypotha.a.us intra.a.a. drug a.ministra.ion meta.olic control nutrient sensor SIRT1 sleep homeosta.is

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Long-term effects of gesta.iona. dia.etes mellitus on the pa.crea. of fema.e mouse offspring

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World Journa. of Dia.etes 2024年第4期15卷 758-768页

作者： Enriqueta.Muñoz-Isla. Edga. Da.id Sa.tia.o-Sa.Ma.tin Edua.do mendoza-Sánchez Héctor Fa.ián Torres-Rodríguez La.ra.Ya.neth Ra.írez-Quinta.illa.Christopher Micha.l Peters Jua. Miguel Jiménez-a.dra.e Unida. a.a.émica.Multidisciplina.ia.Reynosa.a.tlán Universidad Autónoma de TamaulipasReynosa 88740TamaulipasMexico Depa.tment of a.esthesiology Wake Forest University School of MedicineWinston SalemNC 27101United States

Ba.KGROUnD Prolonged feta. exposure to hyperglycemia.ma. increa.e the risk of developing a.norma. glucose meta.olism a.d type-2 dia.etes during childhood,a.olescence,a.d a.ulthood;however,the mecha.isms by which gesta.iona. dia.etes mellitus(GDM)predisposes offspring to meta.olic disorders rema.n *** To qua.tify the nerve a.ons,ma.ropha.es,a.d va.cula.ure in the pa.crea. from a.ult offspring born from mouse da.s with *** GDM wa. induced by *** of streptozotocin(STZ)in ICR mouse *** 12 wk old,fa.ting blood glucose levels were determined in *** 15 wk old,fema.e offspring born from da.s with a.d without GDM were sa.rificed a.d pa.crea.a.were processed for *** qua.tified the density of sensory[ca.citonin gene-rela.ed peptide(CGRP)]a.d tyrosine hydroxyla.e(TH)a.ons,blood vessels(endomucin),a.d ma.ro-pha.es(CD68)in the splenic pa.crea. using confoca. *** Offspring mice born from STZ-trea.ed da.s ha. simila. body weight a.d blood glucose va.ues compa.ed to offspring born from vehicle-trea.ed ***,the density of CGRP+a.d TH+a.ons,endomucin+blood vessels,a.d CD68+ma.ropha.es in the exocrine pa.crea. wa. significa.tly grea.er in offspring from mothers with GDM vs control ***,the microva.cula.ure in the islets wa. significa.tly grea.er,but not the number of ma.ropha.es within the islets of offspring born from da.s with GDM compa.ed to control *** GDM induces neurona.,va.cula.,a.d infla.ma.ory cha.ges in the pa.crea. of a.ult progeny,which ma. pa.tia.ly expla.n the higher propensity for offspring of mothers with GDM to develop meta.olic disea.es.

关键词： Gesta.iona. dia.etes mellitus Immunohistochemistry Confoca. microscopy Pa.crea. Offspring

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