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Ecosystem ma.a.ement in tra.sition in Centra. a.d Ea.tern Europe: the need for a.vision

Ecosystem Hea.th a.d Susta.na.ility 2016年第8期2卷 1-3页

作者： Da.id Va.kář a.drás Báldi Globa. Cha.ge Resea.ch Institute(CzechGlobe) The Czech Academy of SciencesBělidla 986/4a60300 BrnoCzech Republic MTa.Centre for Ecologica. Resea.ch Institute of Ecology and BotanyHungarian Academy of SciencesH-2163 Alkotmány u.2-4VácrátótHungary Corresponding a.dress:Depa.tment of Huma. Dimensions of Globa. Cha.ge Global Change Research Institute CASV Jirchářích 149/611000 Prague 1Czech Republic

It is well esta.lished tha. in current huma.-domina.ed world,environmenta. cha.ge is closely coupled with socio-economic fa.tors,a.d this is reflected in conceptua. fra.eworks of importa.t policies(Día. et a..2015).Huma.s a.e a.versely a.fecting biodiversity a.d clima.e cha.ge on a.pla.eta.y sca.e(Rockström et a..2009).a.thropogenic tra.sforma.ion of ecosystems ha. been driven by ra.id socia. a.d economic cha.ges,ma.ifested by direct drivers such a. la.d use cha.ge a.d clima.e cha.ge(Nelson et a..2006).Centra. a.d Ea.tern Europe(CEE)ha. been a.ra.-idly tra.sitioning region in terms of economic growth a.d politica. *** the colla.se of former Ea.tern Bloc a.d revolutions in severa. CEE countries a.ter 1989,CEE countries ha.e been undergoing politica. a.d economic tra.sforma.ion towa.d democra.y a.d free *** a.cession to the Europea. Union a.so brought in cha.ges of politica. environment a.d ecosystem ma.a.ement possibilities a.d *** socioeconomic cha.ges ha.e influenced environmenta. condition a.d ecosystem ma.a.ement in this region,with cha.ging pres-sures on biodiversity a.d ecosystem *** cha.ges in Centra. a.d Ea.tern Europe ha.e been closely linked especia.ly to a.ricultura. *** exa.ple,inorga.ic fertilizer use in severa. CEE countries dropped in a.single yea. to 25%of its former level a.ter the colla.se of ***,in turn,ha. a. enormous impa.t on fa.mla.d biodiversity(Stoa.e et a..2009).

关键词： Ea.tern Centra. fa.mla.d

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Enha.cement of the ‘tra.tor-bea.’ pulling force on a. optica.ly bound structure

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Light(Science & a.plica.ions) 2017年第1期6卷 136-141页

作者： Ja.a.Da.ková Lukáš Chváta. Ja. Ježek Jindřich Oulehla.Oto Brzoboha.ý Pa.el Zemánek Institute of Scientific Instruments of the Ca. v.v.i.Královopolská147Brno 61264Czech Republic

Recently,increa.ing a.tention ha. been devoted to ma.tering a.new technique of optica. delivery of micro-objects tra.torbea.’1–*** bea.s ha.e uniform intensity profiles a.ong their propa.a.ion direction a.d ca. exert a.nega.ive force tha.,in contra.t to the fa.ilia. pushing force a.socia.ed with ra.ia.ion pressure,pulls the sca.terer towa.d the light *** wa. experimenta.ly observed tha. under certa.n circumsta.ces,the pulling force ca. be significa.tly enha.ced6 if a.non-spherica. sca.terer,for exa.ple,a.linea. cha.n of optica.ly bound objects10–12,is optica.ly *** we demonstra.e tha. motion of two optica.ly bound objects in a.tra.tor bea. strongly depends on theirs mutua. dista.ce a.d spa.ia. *** configura.ion-dependent optica. forces a.d extra.flexibility to our a.ility to control ma.ter with *** these intera.tions opens the door to new a.plica.ions involving the forma.ion,sorting or delivery of colloida. self-orga.ized structures.

关键词： bea. sca.ter mutua.

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Probiotic effects on intestina. fermenta.ion pa.terns in pa.ients with irrita.le bowel syndrome

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World Journa. of Ga.troenterology 2008年第32期14卷 5020-5024页

作者： Ja.queline S Ba.rett Kim ek Ca.a.e Richa.d B Gea.ry Peter M Irving Peter R Gibson Mona.h University Department of Medicine and Department of Gastroenterology Box Hill Hospital

a.M： To determine whether La.toba.illus ca.ei stra.n Shirota.（Ya.ult） ca. a.ter sma.l intestina. ba.teria. overgrowth （SIBO）, a. tested by the la.tulose brea.h test, a.d whether this is a.socia.ed with cha.ges in symptoms in irrita.le bowel syndrome （IBS）. METHODS： 18 pa.ients with IBS （Rome Ⅱ criteria., who showed a. ea.ly rise in brea.h hydrogen with la.tulose （ERBHa.）, consumed 65 mL of Ya.ult da.ly for 6 wk. La.tulose brea.h test wa. repea.ed a. the end of the trea.ment period. Symptoms were recorded da.ly using a.10 cm visua. a.a.ogue sca.e. RESULTS： 14 pa.ients completed the study, 9 （64%） ha. reversa. of ERBHa., with the media. time of first rise in brea.h hydrogen increa.ing from 45 to 75 min （P = 0.03）. There wa. no significa.t improvement in the symptom score with probiotic thera.y, except for wind （P = 0.04）. Pa.ients commencing with a. lea.t modera.e symptoms a.d who no longer ha. ERBHa. a. the end of trea.ment, showed improvement in the overa.l symptoms scores [media. fina. score 5.3 （IQR 3.9-5.9）, 55% reduction; n = 6] to a.grea.er extent tha. those who ha. ha. persisting ERBHa. [fina. score 6.9 （5.0-7.0）, 12% reduction; n = 5; P = 0.18]. CONCLUSION： Ya.ult is effective in a.tering fermenta.ion pa.terns in the sma.l bowel, consistent with reducing SIBO. The loss of ERBHa. wa. a.socia.ed with reduced symptoms. The true interpreta.ion of these findings a.a.ts a.ra.dornised, controlled tria..

关键词： Probiotics Sma.l intestina. ba.teria. overgrowth Brea.h hydrogen testing Functiona. gut symptoms

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Sex differences in the risk of retinopa.hy of prema.urity:a.systema.ic review,frequentist a.d Ba.esia. meta.a.a.ysis,a.d meta.regression

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World Journa. of Pedia.rics 2024年第4期20卷 340-352页

作者： Ta.a.a.M.Hundscheid Silvia.Gulden Moha.a. F.a.muta.ri Fra.tišek Ba.toš Gia.omo Ca.a.la.o Edua.do Villa.or Division of Neona.ology Department of PediatricsMosaKids Children’s HospitalMaastricht University Medical Center(MUMC+)School for Oncology and Reproduction(GROW)Maastricht UniversityP.Debyelaan 25.P.O.Box 58006202 AZ MaastrichtThe Netherlands Neona.a. Intensive Ca.e Unit Sant’Anna HospitalComoItaly Depa.tment of Psychology University of Amsterdam1001 NK AmsterdamThe Netherlands Neona.a. Intensive Ca.e Unit Fondazione IRCCS Ca’Granda Ospedale Maggiore PoliclinicoMilanItaly

Ba.kground Retinopa.hy of prema.urity(ROP)is genera.ly considered to be more frequent in ma.es tha. in ***,it is not known whether sex differences in ROP a.fect a.l degrees of the condition,a.e globa. a.d ha.e cha.ged a. neona.ology ha. *** a.med to conduct a.systema.ic review a.d meta.a.a.ysis of studies a.dressing sex differences in the risk of developing *** PubMed/MEDLINE a.d Emba.e da.a.a.es were *** frequentist,ra.dom-effects risk ra.io(RR)a.d 95%confidence interva.(CI)were *** model a.era.ed(BMa.meta.a.a.ysis wa. used to ca.cula.e the Ba.es fa.tors(BFs).The BF10 is the ra.io of the proba.ility of the da.a.under the a.terna.ive hypothesis(H1)over the proba.ility of the da.a.under the null hypothesis(H0).Results We included 205 studies(867,252 infa.ts).Frequentist meta.a.a.ysis showed a.positive a.socia.ion between ma.e sex a.d severe ROP(113 studies,RR=1.14,95%CI=1.07–1.22)but no a.socia.ion with a.y ROP(144 studies,RR=1.00,95%CI=0.96–1.03).BMa.showed extreme evidence in fa.or of H1 for severe ROP(BF10=71,174)a.d strong evidence in fa.or of H0 for a.y ROP(BF10=0.05).The a.socia.ion between ma.e sex a.d severe ROP rema.ned sta.le over time a.d wa. present only in cohorts from countries with a.high or high-middle sociodemogra.hic *** Our study confirms the presence of a.ma.e disa.va.ta.e in severe ROP but not in less severe forms of the *** a.e va.ia.ions in the sex differences in ROP,depending on geogra.hica. loca.ion a.d sociodemogra.hic level of the countries.

关键词： Oxida.ive stress Retinopa.hy of prema.urity Sex cha.a.teristics

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Compa.ison of the probiotic cha.a.teristics of La.tic a.id Ba.teria.(La.) isola.ed from sourdough a.d infa.t feces

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Food Bioscience 2022年第3期47卷 992-997页

作者： Ya.emin Ka.a.Ta.yibe Erten Melike Vurma. Hümeyra.İspirli Ömer Şimşek Enes Dertli Ba.burt University Central Research LaboratoryBayburtTurkey Ba.burt University Department of Nutrition and DieteticsFaculty of Heath SciencesBayburtTurkey Pa.ukka.e University Department of Food EngineeringFaculty of EngineeringDenizliTurkey Yıldız Technica. University Department of Food EngineeringFaculty of Chemical and Metallurgical EngineeringİstanbulTurkey

Probiotics a.e beneficia. microorga.isms with certa.n cha.a.teristics such a. surviva. under ga.trointestina. conditions,a.hesion to intestina. surfa.e a.d different functions which result in severa. hea.th benefits to *** this rega.ds,this study a.med to isola.e La.tic a.id Ba.teria.(La.) from sourdough a.d huma. feces a. two different environments a.d to test their potentia. probiotic *** tota. nine distinct isola.es were a.sessed with severa. probiotic functions such a. in vitro a.hesion to huma. colon cells,a.timicrobia. a.tivities a.d surviva. under ha.sh ga.trointestina. *** genera.,distinct stra.ns showed strong a.timicrobia. a.tivity a.a.nst the pa.hogenic a.d funga. stra.ns tested in this ***,the a.hesion levels to HT29 cells were determined between 0.29 % a.d 9.54% a.d La.toba.illus pa.a.a.ei F7B showed the highest *** isola.es tolera.ed the bile sa.t a.ter 24 h a.d the infa.t feces isola.es showed good surviva. cha.a.teristics a. pH 4.

关键词： Probiotic Sourdough Infa.t feces a.hesion

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Recurrent ca.pa. tunnel syndrome: Eva.ua.ion a.d trea.ment of the possible ca.ses

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World Journa. of Clinica. Ca.es 2018年第10期6卷 365-372页

作者： a.met Ero?lu Enes Sa.? a.i K?va.? Topuz Ha.a. ?im?ek Serha. Pusa. Depa.tment of Neurosurgery Haydarpa?a Sultan Abdülhamid Education and Research Hospital Depa.tment of Orthopa.dics a.d Tra.ma.ology Near East University Hospital Depa.tment of Neurosurgery Baypark Hospital

a.M To investiga.e the ca.ses of the recurrent ca.pa. tunnel syndrome(CTS) a.d implemented surgica. *** Four hundred a.d eighty-seven pa.ients, who were dia.nosed with CTS a.d underwent surgica. intervention between October 2016 a.d September 2007, were eva.ua.ed in this retrospective study. The a.e, gender, physica. eva.ua.ion findings, electrophysiologica. exa.ina.ion reports a.d implemented surgica. trea.ment methods were *** Thirty-nine of the ca.es were opera.ed due to recurrent CTS. Further exa.ina.ion of the pa.ients with recurrent CTS revea.ed tha. ten ca.es ha. dia.etic polyneuropa.hy, three ca.es ha. hypothyroidism, two ca.es ha. rheuma.oid a.thritis a.d one ca.e ha. systemic a.yloidosis. Postopera.ive electromyogra.hy confirmed the neuropa.hy wa. due to systemic disea.es. The rema.ning 23 pa.ients with recurrent CTS did not ha.e a.y systemic disea.e a.d a.l of them ha. a.plied previously to a.other hea.th center. CONCLUSION We concluded tha. the recurrence ra.es in CTS might be decrea.ed with explora.ion a.d incision of the entire tra.sverse liga.ent. Da.a.e to the motor a.d sensory bra.ches of the media. nerve could be a.oided with a. incision on the ulna. side.

关键词： Ca.pa. tunnel Electromyogra.hy Media. nerve retrospective study Entra.ment neuropa.hies

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Role of ciprofloxa.in in pa.ients with cholesta.is a.ter endoscopic retrogra.e chola.giopa.crea.ogra.hy

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World Journa. of Ga.troenterology 2007年第2期13卷 276-279页

作者： Tha.ee Ra.a.a.hu-ek Pitcha.a.Pra.a.pha.it Ka.in Leela.a. Sucha.t Cha.ta.ibul Sukij Pa.pima.ma. Somboon Subwongcha.oen Jera.a. Wa.na.ra.ert Depa.tment of Surgery Rajavithi Hospital Bangkok 10400 Thailand

a.M： To determine the role of ciprofloxa.in in reducing chola.gitis in cholesta.ic pa.ients with a.equa.e bilia.y dra.na.e a.ter endoscopic retrogra.e chola.giopa.crea.ogra.phy （ERCP）. METHODS： a.ra.domized, controlled tria. wa. performed in 48 cholesta.ic pa.ients a. Ra.a.ithi Hospita. （Tertia.y Referra. Center for ERCP： 600 ca.es per yea.）. a.l the 48 pa.ients received 200 mg ciprofloxa.in intra.enous injection for 30 min before sta.ting a.y procedures, a.d then were ra.domly divided in two groups. Twenty-two pa.ients in study group continua.ly received dprofloxa.in until 48 h a.ter ERCP. Ca.ses of bilia.y obstruction, ba.teriology of bile a.d blood （in chola.gitis） a.d dinica. chola.gitis were recorded. RESULTS： Forty-eight pa.ients were enrolled a.d divided into continuous ciprofloxa.in trea.ment group （/7 = 22） a.d discontinuous ciprofloxa.in trea.ment group （n = 26）. During ERCP, stones were found in 22 pa.ients, ma.igna.t disea.es in 24 pa.ients a.d other pa.hologic lesions in 5 pa.ients. One （4.5%） of the 22 pa.ients who received ciprofloxa.in a.d 2 （6.3%） of the 26 pa.ients who discontinued ciprofloxa.in a.ter ERCP developed chola.gitis （rela.ive risk = 0.71; 95% CI = 0.14-3.65; P = 0.88）. Ba.terobilia.wa. found in 27 （56.3%） out of 48 pa.ients. E. coli a.d Streptococcus virida.s were the most common orga.isms. CONCLUSION： Continua. use of ciprofloxa.in in pa.ients with cholesta.is a.ter a.equa.e bilia.y dra.na.e procedures pla.s no role in reducing chola.gitis.

关键词： a.tibiotic Cholesta.is Chola.gitis Endoscopic retrogra.e chola.giopa.crea.ogra.hy Bilia.y dra.na.e

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Effect of Sola.um sura.tense seed on the oxida.ive potentia. of ca.da.epididyma. sperma.ozoa

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a.ia. Pa.ific Journa. of Tropica. Biomedicine 2012年第1期2卷 21-23页

作者： Thiruma.a. T Da.id E Viviya. Thera.a.S Eluma.a. ek Post Gra.ua.e a.d Resea.ch Depa.tment of Zoology Voorhees CollegePhysiology Wing

Objective:To eva.ua.e the effect of a.ueous seed extra.t of Sola.ium sura.lense(***)on the oxida.ive potentia. of ca.da.cpididyma. ***:*** seed extra.t wa. ora.ly a.ministered a. the dosa.e of 10 mg/kg *** 15 da.s,a.ter which a.pa.ta.e tra.sfera.e(a.T),a.a.ine tra.sfera.e(a.T),gluta.a.e dehydrogena.e(GDH),citric a.id a.d isocitra.e dehydrogena.e(ICDH)were ***:The a.tivity levels of the enzymes a.T a.d a.T,which a.e considered to be the a.drogenicity in the sperm suspension,were depleted in the extra.t fed *** a.tivity level of the enzyme ICDH,wa. reduced significa.tly in the trea.ed group(Pa. be concluded tha. the ora. a.ministra.ion of the a.ueous seed extra.t of *** ca. deplete the oxida.ive stress of ca.da.epididyma. sperma.ozoa.in a.bino ra.s.

关键词： Sperm Sola.um sura.tense Contra.eption a.tifertility

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应用多重连接探针扩增法简便高效检测Pra.er-Willi综合征的基因缺失(英文)

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北京大学学报（医学版） 2005年第1期37卷 64-67页

作者： Va.LIP Depa.tment of La.ora.ory Medicine

Objective: Pra.er-Willi syndrome (PWS) is cha.a.terized by severe hypotonia.a.d feeding difficulties in ea.ly infa.cy, followed by excessive ea.ing a.d gra.ua. development of morbid obesity in la.er infa.cy or ea.ly childhood. Pa.ients with PWS a.e often too young to ma.ifest sufficient fea.ures or ha.e a.ypica. findings, ma.ing genetic testing importa.t to confirm the dia.nosis of PWS. a.proxima.ely 99% of pa.ients with PWS ha.e a.dia.nostic a.norma.ity in the pa.ent-specific methyla.ion imprint within the Pra.er-Willi critica. region (PWCR) a. chromosome 15q11.2-q12. Of them, 70% ha.e a.pa.erna. deletion; 25% ha.e a.ma.erna. unipa.enta. disomy (UPD); a.d a.e a.muta.ion in the imprinting center. Methods: Current techniques ca. identify a.dia.nostic a.norma.ity, such a. pa.erna. deletion or ma.erna. UPD for most of pa.ients with PWS, but they a.e la.or-intensive a.d cost-expensive. Multiplex liga.ion-dependent probe a.plifica.ion (MLPa. is a.novel, simple, a.d cost-effective technique for a.a.ysis of rela.ive qua.tifica.ion in a.single a.sa., which ha. recently been a.plied for the detection of genomic deletions, duplica.ions, a.d a.plifica.ions in a.va.iety of genes. Results: Six out of 20 pa.ients referred for genetic dia.nosis of PWS were found to ha.e a.deletion by MLPa. confirmed by FISH a.d DNa.methyla.ion a.a.ysis with 100% concorda.ce. Conclusion: MLPa.s high sensitivity a.d specificity for deletion detection is the sa.e a. FISH or Southern blot ba.ed a.a.ysis. a.ditiona. colla.ora.ive effort for developing a.d va.ida.ing the complete MLPa.PWS a.sa., for not only detecting deletion but a.so identifying methyla.ion a.norma.ity, is on going.

关键词： Pra.er-Willi综合征多重连接探针扩增法基因缺失遗传筛查

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Compa.a.ive phytochemica. a.a.ysis of Coffea.bengha.ensis Roxb. Ex Schult, Coffea.a.a.ica.L. a.d Coffea.liberica.Hiern

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a.ia. Pa.ific Journa. of Tropica. Medicine 2018年第8期11卷 480-485页

作者： éva.Brigitta.Pa.a. ágnes a.berti Orsolya.Csernák Szilvia.Stra.czinger Nóra.Pa. Depa.tment of Pha.ma.ognosy Faculty of Pharmacy University of Pécs Depa.tment of Pha.ma.ognosy Faculty of Pharmacy Semmelweis University Depa.tment of Pla.t Biology Faculty of Sciences University of Pécs

Objective: To ma.e phytochemica. studies of the lea., perica.p a.d seed of Coffea.bengha.ensis(C. Bengha.ensis) compa.ed with those of the widely known Coffea.a.a.ica.a.d Coffea.liberica. Methods: The sa.ple extra.ts were prepa.ed by Soxhlet-extra.tion. Polyphenol content wa. a.a.yzed by HPLC-ESI-MS/MS, the identifica.ion wa. ca.ried out ba.ed on the retention time, UV a.d ma.s spectra.of sta.da.ds a.d litera.ure da.a.of the detected compounds. Results: Phenolic a.ids like ca.feoylquinic a.ids, dica.feoylquinic a.ids, feruloylquinic a.ids a.d couma.oylquinic a.id, a. well a. ma.giferin were detected a. ma.n constituents in a.l extra.ts. Procya.idin trimers were present exclusively in the lea.es. In C. bengha.ensis, ma.n constituents were 5-ca.feoylquinic a.id a.d 4-ca.feoylquinic a.id. Fla.a.-3-ols were described in a.l imma.ure a.d ma.ure perica.p a.d lea. extra.ts. Even though 4-feruloylquinic a.id wa. described in both imma.ure a.d ma.ure seed, dica.feoylquinic a.ids were identified only in the ma.ure seed extra.ts. Ma.giferin wa. present in the lea., ma.ure perica.p a.d seed. Conclusions: These a.a.yses provide new chemota.onomica. da.a.for the selected coffees, especia.ly for C. bengha.ensis. Due to its high polyphenol content, our results indica.e its significa.ce of providing new da.a.a. a.possible source for industry.

关键词： Coffee LC-MS Polyphenols Ca.feoylquinic a.ids

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