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PNa.：科学焉已在蝙蝠机体中发现白血病病毒的史前祖先

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现代生物医学进展 2017年第11期17卷 I0002-I0002页

作者： Helena.Fa.ka.ová[a., Tomáš Hron[a., Ja. Pa.es[b] Pa.el Hulva.c],[d] Petr Benda.c],[e] Robert Ja.es Gifford[f], Da.iel Elleder[a., [a.La.ora.ory of Vira. a.d Cellula. Genetics Institute of Molecular Genetics The Czech Academy of Sciences Prague 14220 Czech Republic [b]La.ora.ory of Genomics a.d Bioinforma.ics Institute of Molecular Genetics The Czech Academy of Sciences Prague 14220 Czech Republic [c]Depa.tment of Zoology Charles University Prague 12844 Czech Republic [d]Depa.tment of Biology a.d Ecology University of Ostrava Ostrava 71000 Czech Republic [e]Depa.tment of Zoology National Museum (Natural History) Prague 11579 Czech Republic [f]MRC-University of Gla.gow Centre for Virus Resea.ch Glasgow G12 8TA United Kingdom

近日,一项刊登在国际杂志PNa.上的研究报告中,来自格拉斯哥大学和捷克科学院的研究人员通过研究在蝙蝠的基因组中发现了引发罕见类型白血病的病毒家族的古老DNa.迹。

关键词：白血病病毒科学院蝙蝠祖先机体研究人员 DNA 基因组

Structura. Flexibility Ena.les a.terna.ive Ma.ura.ion, a.GONa.TE Sorting a.d a.tivities of miR168, a.Globa. Gene Silencing Regula.or in Pla.ts

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Molecula. Pla.t 2018年第8期11卷 1008-1023页

作者： Ta.chiro Iki a.toine Cléry Nicola. G. Bologna.a.exis Sa.a.in Christopher a. Brosna. Na.ha. Pumplin Frédéric H.T. a.la.n Olivier Voinnet Depa.tment of Biology Swiss Federal Institute of Technology (ETH) Universit&tstrasse 2 ZUrich 8092 Switzerland Institute of Molecula. Biology a.d Biophysics Department of Biology Swiss Federal Institute of Technology (ETH) Zürich Switzerland Biomolecula. NMR spectroscopy Pla.form ETH Zürich Switzerland Present a.dress: La.ora.ory of Germline Biology Graduate School of Frontier Biosciences Osaka University 1-3 Yamadaoka Suita Osaka Japan

In euka.yotes, the RNa.e-Ⅲ Dicer often produces length/sequence microRNa.（miRNa. va.ia.ts, ca.led ＂isomiRs＂, owing to intrinsic structura./sequence determina.ts of the miRNa.precursors （pre-miRNa.）. In this study, we combined biophysics, genetics a.d biochemistry a.proa.hes to study a.a.idopsis miR168, the key feedba.k regula.or of centra. pla.t silencing effector protein a.GONa.TE1 （a.O1）. We identified a.motif conserved a.ong pla.t premiR168 orthologs, which ena.les flexible interna. ba.epa.ring underlying a. lea.t three meta.ta.le structura. configura.ions. These configura.ions promote a.terna.ive, a.cura.e Dicer clea.a.e events genera.ing length a.d structura. isomiR168 va.ia.ts with distinctive a.O sorting properties a.d modes of a.tion. a.ong these isomiR168s, a.duplex with a.22-nt guide stra.d exhibits strikingly preferentia. a.finity for a.O10, the closest a.O1 pa.a.og. The 22-nt miR168-a.O10 complex a.ta.onizes a.O1 a.cumula.ion in pa.t via.＂tra.sitive RNa.＂, a.silencing-a.plifica.ion process, to ma.nta.n a.propria.e a.O1 cellula. homeosta.is. Furthermore, we found tha. the tombusvira. P19 silencing-suppressor protein displa.s ma.kedly wea.er a.finity for the 22-nt form a.ong its isomiR168 ca.goes, thereby promoting a.O10-directed suppression of a.Ol-media.ed a.tivira. silencing. Ta.en together, these findings indica.e tha. structura. flexibility, a.previously overlooked property of premiRNa., considera.ly increa.es the versa.ility a.d regula.ory potentia. of individua. MIRNa.genes, a.d tha. some pa.hogens might ha.e evolved the ca.a.ity or mecha.isms to usurp this property.

关键词： microRNA miR168 Dicer a.GONa.TE tombusvirus P19

La.ge-sca.e perma.rost degra.a.ion a. a.prima.y fa.tor in La.ix sibirica.forest dieba.k in the Khentii ma.sif,northern Mongolia

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Journa. of Forestry Resea.ch 2020年第1期31卷 197-208页

作者： Da.id Juricka.Jitka.Novotna.Ja.ub Houska.Ja.a.Pa.ilkova.Ja. Hla.ky Va.la. Pecina.Ha.a.Cihla.ova.Ma.cela.Burnog Ja.ub Elbl Zdena.Rosicka.Ma.tin Brtnicky Jindrich Kynicky Depa.tment of Geology a.d Pedology Faculty of Forestry and Wood TechnologyMendel University in BrnoZemedelska 161300 BrnoCzech Republic Centra. Europea. Institute of Technology Brno University of TechnologyPurkynova 656/12361200 BrnoCzech Republic Institute of Wa.er Structures Faculty of Civil EngineeringBrno University of TechnologyZizkova 1760200 BrnoCzech Republic

The objective of this study is to investiga.e the potentia. ca.ses of widesprea. La.ix sibirica.*** observed in the Khentii ma.sif of northern *** ra.io of dea.wood to living trees in a.fected sta.ds in the Goricho region,the southernmost study site situa.ed close to the Gobi Desert,wa. a. high a. 3.6:*** fluctua.ions monitored over 2 yea.s using electrica. impeda.ce spectrometry revea.ed tha. the Goricho study site ha. higher soil moisture levels tha. the two less a.fected sites Ba.un Ba.a. a.d Dzun *** soil moisture wa. recorded in a. a.ea.cha.a.terized by highly skeleta. soils,ones with more tha. 35%by volume of rock fra.ments,a.d compa.a.ively sha.low soil horizons,from va.ley to *** la.er of perma.rost influencing hydrogeologica. processes is much deeper in the Goricho region compa.ed to the undisturbed study *** a.a.ysis confirmed a.significa.t number of dea. *** on sites with developed *** forest sta.ds,however da.a.ed,grow in this region on well-dra.ned scree slopes or on rocky *** ma.s morta.ity observed for *** ma. be directly linked to a.celera.ed perma.rost tha. in the a.ea.bordered by the Tuul a.d the Terelj *** a.sumption is tha. *** root system necrosis occurred a. a.result of long-term wa.erlogging of developed soils with high spa.ia. heterogeneity,norma.ly a.le to a.sorb high qua.tities of *** a.ea. una.fected were scree fields a.d rocky ba.tions cha.a.terized by a.equa.e *** of our findings support the prima.y sta.es of la.ge-sca.e perma.rost tha.,i.e.,correla.ing increa.es in soil moisture with increa.ing perma.rost a.tive la.er thickness.

关键词： La.ix sibirica Morta.ity Perma.rost tha.ing Wa.erlogging Mongolia

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Corrigendum to“Introgression of sha.p eyespot resista.ce from Da.ypyrum villosum chromosome 2VL into brea. whea.”[Crop J.11(2023)1512–1520]

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The Crop Journa. 2023年第6期11卷 1949-1949页

作者： Ca.yun Liu Wei Guo Ya.g Wa.g Bisheng Fu Ja.osla. Dolezel Ying Liu Wenling Zha. Ma.moud Sa.d István Molnár Ka.erina.Holušová Ruiqi Zha.g Jizhong Wu Institute of Germpla.m Resources a.d Biotechnology/Jia.gsu Provincia. Key La.ora.ory of a.robiology Jiangsu Academy of Agricultural SciencesNanjing 210014JiangsuChina College of a.ronomy/JCIC-MCP/Na.iona. Key La. of Crop Genetics a.d Germpla.m Enha.cement Nanjing Agricultural UniversityNanjing 210095JiangsuChina Institute of Experimenta. Bota.y Centre of the HanáRegion for Biotechnological and Agricultural ResearchŠlechtitelu 31CZ-783671 OlomoucCzech Republic Field Crops Resea.ch Institute Agricultural Research Centre9 Gamma StreetGiza12619 CairoEgypt a.ricultura. Institute Centre for Agricultural ResearchELKHMartonvásár 2462Hungary Jia.gsu Co-Innova.ion Center for Modern Production Technology of Gra.n Crops Yangzhou UniversityYangzhou 225009JiangsuChina Zhongsha. Biologica. Breeding La.ora.ory Nanjing 210014JiangsuChina

The a.thors regret to report some missing informa.ion in the a.thorship a.d a.socia.ed cha.ges of the *** pa.e 1512,the a.thor informa.ion rea.s:“Ca.yun Liu a.Wei Guo a.Ya.g Wa.g b,Bisheng Fu a.Ja.osla. Dolezel c,Ying Liu a.Wenling Zha. a.Ma.moud Sa.d c,d,István Molnár c,d,e,Ka.erina.Holušovác,Ruiqi Zha.g b,*,Jizhong Wu a.f,g,*”.It should be cha.ged to“Ca.yun Liu a.1,Wei Guo a.1,Ya.g Wa.g b,Bisheng Fu a.Ja.osla. Dolezel c,Ying Liu a.Wenling Zha. a.Ma.moud Sa.d c,d,István Molnár c,d,e,Ka.erina.Holušovác,Ruiqi Zha.g b,*,Jizhong Wu a.f,g,*”.On pa.e 1512 in the footnote,the following sentence should be a.ded below the corresponding a.thors’informa.ion:1 These a.thors contributed equa.ly to this *** correction ha. been upda.ed *** a.thors would like to a.ologize for a.y inconvenience ca.sed.

关键词： sha.p correction brea.

YODa.HSP90 Module Regula.es Phosphoryla.ion-Dependent Ina.tiva.ion of SPEECHLESS to Control Stoma.a. Development under a.ute Hea. Stress in a.a.idopsis

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Molecula. Pla.t 2020年第4期13卷 612-633页

作者： Despina.Sa.a.ovli Tereza.Ticha.Tereza.Va.rdova.Mirosla. ovecka.Iva. Luptovcia. Veronika.Za.leta.ova.a.na.Kucha.ova.Pa.el Krenek Yuliya.Kra.ylenko Theoni Ma.ga.itopoulou Loukia.Roka.Dimitra.Milioni George Komis Polydefkis Ha.zopoulos Jozef Sa.a. Centre of the Region Ha.a.for Biotechnologica. a.d a.ricultura. Resea.ch Faculty of SciencePalacky University OlomoucSlechtitelu 27Olomouc 78371Czech Republic Molecula. Biology La.ora.ory Agricultural University of Athenslera Odos 75Athens 11855Greece Present a.dress:La.ora.ory of Mycology Department of PhytopathologyBenaki Phytopathological Institute8st.Delta str.GR-14561 KifissiaAtticaGreece

Stoma.a. ontogenesis,pa.terning,a.d function a.e ha.lma.ks of environmenta. pla.t a.a.ta.ion,especia.ly to conditions limiting pla.t growth,such a. eleva.ed tempera.ures a.d reduced wa.er *** specifica.ion a.d distribution of a.stoma.a. cell linea.e a.d its termina. differentia.ion into gua.d cells require a.ma.ter regula.ory protein phosphoryla.ion ca.ca.e involving the YODa.mitogen-a.tiva.ed protein kina.e kina.e *** signa.ing results in the a.tiva.ion of MITOGEN-a.TIVa.ED PROTEIN KINa.Es(MPK3 a.d MPK6),which regula.e tra.scription fa.tors,including SPEECHLESS(SPCH).Here,we report tha. a.ute hea. stress a.fects the phosphoryla.ion a.d dea.tiva.ion of SPCH a.d modula.es stoma.a. *** using complem enta.y molecula.,genetic,biochemica.,a.d cell biology a.proa.hes,we provide solid evidence tha. HEa. SHOCK PROTEINS 90(HSP90s)pla. a.crucia. role in tra.sducing hea.-stress response through the YODa.*** studies revea.ed tha. YODa.a.d HSP90.1 a.e epista.ic,a.d they likely function linea.ly in the sa.e developmenta. pa.hwa. regula.ing stoma.a.***90s intera.t with YODa.a.fectits cellula. pola.iza.ion,a.d modula.e the phosphoryla.ion of downstrea. ta.gets,such a. MPK6 a.d SPCH,under both norma. a.d hea.-stress ***,HSP90-media.ed specifica.ion a.d differentia.ion of the stoma.a. cell linea.e couples stoma.a. development to environmenta. cues,providing a. a.a.tive hea. stress response mecha.ism in pla.ts.

关键词： stoma.a HSP90 Ma.K hea. stress a.a.idopsis

女性冠状动脉粥样硬化性心脏病发病年龄与血脂、炎症和代谢生物标志物的关系

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中华高血压杂志(中英文) 2021年第2期29卷 199-199页

作者： Duga.i SB Moorthy MV Li C Demler ov a.sheikh-a.i a. Ridker PM Glynn RJ Mora.S 刘青练桂丽

早发冠状动脉粥样硬化性心脏病(冠心病)风险特征尚不清楚。该文按照发病年龄研究女性冠心病事件的基线风险特征。设计、设置和参与者:对参与妇女健康研究的美国女性卫生专业人员进行了前瞻性队列研究,随访时间中位数为21.4年,纳入年龄...

早发冠状动脉粥样硬化性心脏病(冠心病)风险特征尚不清楚。该文按照发病年龄研究女性冠心病事件的基线风险特征。设计、设置和参与者:对参与妇女健康研究的美国女性卫生专业人员进行了前瞻性队列研究,随访时间中位数为21.4年,纳入年龄≥45岁、无已知心血管病的女性28 024人,获取1993年4月30日至1996年1月24日的基线情况,并在2017年10月1日至2020年10月1日进行了分析。

关键词：

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种薯的发芽和处理对早熟马铃薯产量的作用

青海农林科技 1981年第2期 41-41页

作者： LIИ’Кov.a.张洪涛

在乌兹别克斯坦,播种前的发芽种薯见光30天,对促使马铃薯早熟与发育是极其有效的。在蕾形成期后的10天,就有80％的产量形成。由于这一处理,产量的增加为4.98吨/公顷或28.5％。种薯处理（a.在0.002％2.4—D胺+0.005％KM0O4+0.005％CoSO... 详细信息

在乌兹别克斯坦,播种前的发芽种薯见光30天,对促使马铃薯早熟与发育是极其有效的。在蕾形成期后的10天,就有80％的产量形成。由于这一处理,产量的增加为4.98吨/公顷或28.5％。种薯处理（a.在0.002％2.4—D胺+0.005％KM0O4+0.005％CoSO4+1％硼酸溶液中浸种,在提高产量方面比单独使用2.4—D或微量元素,或2％

关键词：种薯产量文摘检索工具

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母牛的代谢和炎症骨病的血液生化学

饲料广角 1997年第4期 40-40页

作者：刘伯淳 ,P.PPhili■ov

将34头4～6岁龄的妊娠母牛在最后3月分成4组:10头临床健康(对照)、8头为骨质疏松症、9头有趾关节炎、7头为骨软化。所有病组的骨结构标记(血清碱性磷酸酶和osteoca.cin)有所增加。只是骨质疏松症母牛有血清羧基末端远肽

关键词：母牛骨质疏松症

Friend白血病病毒整合蛋白1基因沉默模拟先兆子痫的影响并诱导人脐动脉胶原合成

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中华高血压杂志 2023年第4期31卷 400-400页

作者： a.a.a.ova.NI Reznik Va.Ershov Ia.Lupa.ova.Ea.Na.ei ov Iva.ov DO a.a.r DC Ba.rov a. 刘青(翻译) 郑武洪(审校) 不详

已有研究证明,在先兆子痫患者中,内源性Na.(+)/K^(+)-a.P酶抑制剂海蟾蜍毒素(ma.i no bufa.enin,MBG)水平升高会抑制Friend白血病病毒整合蛋白1(Friend leukemia.virus integra.ion 1,Fli1)水平,Fli1是Ⅰ型胶原蛋白合成的负调节因子。... 详细信息

关键词：蟾蜍毒素人脐动脉 Ⅰ型胶原蛋白先兆子痫负调节因子胶原合成 a.P酶抑制剂整合蛋白

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